haloperidol and desipramine

haloperidol has been researched along with desipramine in 157 studies

Research

Studies (157)

Timeframe	Studies, this research(%)	All Research%
pre-1990	81 (51.59)	18.7374
1990's	24 (15.29)	18.2507
2000's	30 (19.11)	29.6817
2010's	21 (13.38)	24.3611
2020's	1 (0.64)	2.80

Authors

Authors	Studies
Baldy, WJ; Davis, CB; DiStefano, DL; Elgin, RJ; Fedde, CL; Kesslick, JM; Martin, GE; Mathiasen, JR; Scott, MK; Shank, RP	1
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Costanzo, MJ; Gardocki, JF; Maryanoff, BE; McComsey, DF; Nortey, SO; Schneider, CR; Setler, PE; Shank, RP	1
Andrews, PR; Craik, DJ; Martin, JL	1
Lucas, RA; Smith, RG; Wasley, JW	1
Goodman, MM; Kabalka, GW; Kung, HF; Kung, MP; Switzer, R	1
Bauer, C; Caldwell, L; Kinnier, WJ; Lancaster, J; McMillan, B; Price, CH; Sweetnam, PM	1
Booth, RG; Brown, RL; Bucholtz, EC; Tropsha, A; Wyrick, SD	1
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B	1
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA	1
Keserü, GM	1
Bacsó, Z; Cianfriglia, M; Fenyvesi, F; Goda, K; Kappelmayer, J; Lustyik, G; Nagy, H; Szabó, G; Szilasi, M	1
Caron, G; Ermondi, G	1
Nagashima, R; Nishikawa, T; Tobita, M	1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J	1
Lombardo, F; Obach, RS; Waters, NJ	1
Jia, L; Sun, H	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Bleich, S; Kornhuber, J; Rupprecht, R; Terfloth, L; Wiltfang, J	1
Ahman, M; Holmén, AG; Wan, H	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Giordanetto, F; Leach, AG; Zachariae, U	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Glen, RC; Lowe, R; Mitchell, JB	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Sen, S; Sinha, N	1
Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ	1
Carmody, LC; Dandapani, S; Donckele, E; Feng, Y; Fernandez, C; Germain, AR; Gupta, PB; Lander, ES; Morgan, B; Munoz, B; Nag, PP; Palmer, M; Perez, JR; Schreiber, SL; Verplank, L	1
Dalvie, D; Loi, CM; Smith, DA	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Bandyopadhyaya, A; Rajagopalan, DR; Rajagopalan, P; Rajagopalan, R	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Acevedo, O; Dasararaju, G; Devadasan, V; Halakova, D; Jayaprakash, V; Kovacikova, L; Mohd Siddique, MU; Mondal, SK; Prnova, MS; Shilkar, D; Stefek, M; Thakur, A; Yasmin, S	1
Dawes, P; Redfern, PH	1
Bonta, IL; Dzoljic, MR; Godschalk, M	1
McMillen, BA; Shore, PA	1
Richelson, E	1
Løvstad, RA	1
Lehmann, K; Schmidt, J	1
Buckley, JP; Lokhandwala, MF	1
Keim, KL; Sigg, EB	1
Buckley, JP; Coats, JT; Lokhandwala, MF	1
Anderson, WG; Erhardt, PW; Gorczynski, RJ; Stout, DM	1
Adèr, JP; Korf, J	1
German, DC; Kiser, RS; McMillen, BA; Sanghera, MK; Shore, PA	1
Erinoff, L; Heller, A; Hoffmann, PC; MacPhail, RC; Seiden, LS	1
Colpaert, FC; Janssen, PA; Niemegeers, CJ	1
Finch, L; Hersom, A; Hicks, P	1
Krupp, P; Wesp, M	1
Bissette, G; Levant, B; Myers, B; Nemeroff, CB	1
Briley, M; Moret, C	1
Carboni, E; Di Chiara, G; Frau, R; Tanda, GL	2
Bickel, MH; Jachertz, G; Moor, MJ; Steiner, SH	1
Saltz, BL	1
Kirkby, RD; Kokkinidis, L	1
Kucharik, RF; Moyer, JA; White, SM	1
Hernandez, DE; Jennes, L	1
Borsini, F; Lecci, A; Meli, A; Volterra, G	1
Orthen-Gambill, N; Salomon, M	1
Broadley, KJ; Williamson, KL	1
de Jong, W; van den Buuse, M	1
McElroy, JF; O'Donnell, JM; Stimmel, JJ	1
Cavicchia, S; Dewey, DA; DiJohnson, C; Kimes, I; Kramer, MS; Little, P; Schmidt, R; Sheves, P; Vogel, WH	1
Fu, P; Lesser, IM; Lin, KM; Nuccio, I; Poland, RE	1
Britton, KT; Koob, GF	1
McElroy, JF; O'Donnell, JM	1
Cools, AR; Ellenbroek, BA; Honig, WM; Peeters, BW	1
Bergman, J; Spealman, RD	1
Cools, AR; Ellenbroek, BA; Gispen, WH; Spruijt, BM	1
Anderson, B; Severson, JA	1
Fujiwara, M; Kataoka, Y; Ohta, H; Oishi, R; Ueki, S	1
Balon, R; Berchou, R; Mahr, GC	1
Malek-Ahmadi, P	1
Cagiano, R; Cuomo, V; De Salvia, MA; Maselli, MA; Racagni, G; Renna, G	1
Cubeddu, LX; Hoffmann, IS; Talmaciu, RK	1
Czyrak, A; Klimek, V; Mogilnicka, E; Wedzony, K	1
Jatlow, PI; Nelson, JC; Price, LH	1
Fischer, W; Heydenreich, F; Rabending, G; Streubel, FR	1
Jackson, DM; Jenkins, OF	1
Fibiger, HC; Martin-Iverson, MT; Ortmann, R	1
Feigenbaum, JJ; Yanai, J	1
Baer, L; Jenike, MA; Minichiello, WE	1
Davis, JM; Javaid, JI; Maiorano, M	1
Finch, L	1
Berndt, S; Schwabe, U	1
Bruun, A; Ehinger, B	1
Consolo, S; Garattini, S; Ladinsky, H; Peri, G	1
Hamilton, TC	1
Fuxe, K; Sjöqvist, F	1
Kadzielawa, K	1
Komissarov, IV; Talalaenko, AN; Zin'kovskaia, LIa	1
Lassen, JB	1
Gessa, GL; Tagliamonte, A	1
Gelb, F; Gurfein, L; Kammerer, M; Wartel, R; Weil, J; Wysoki, V	1
Gajda, L; Grabowska, M; Maj, J	1
Garriott, JC; Stolman, A	1
Iversen, LL; Johnston, GA	1
Rohte, O	2
Garattini, S; Morselli, PL; Rizzo, M; Zaccala, M	1
Nybäck, H; Sedvall, G	1
Borzecki, Z; Nybäck, H; Sedvall, G	1
Furlong, FW; Hendrie, H; Luby, ED	1
Heilig, P; Heiss, WD; Hoyer, J	1
Burchinsky, SG	1
Schechter, MD	1
Bergstrom, DA; Walters, JR	1
Borsini, F; Nowakowska, E; Samanin, R	1
Dall'Olio, R; Gaggi, R; Gandolfi, O; Montanaro, N; Vaccheri, A	1
Karoum, F	1
Kurumiya, S; Olds, ME; Takeichi, T; Umemoto, M	1
Buda, M; De Simoni, G; Gonon, F; Pujol, JF	1
Nobrega, JN; Wiener, NI	1
McRae-Degueurce, A; Milon, H	1
Jones, RS; Olpe, HR; Steinmann, MW	1
Hirschmann, N; Nir, I	1
Blavet, N; DeFeudis, FV	1
Corbett, R; Cornfeldt, M; Dunn, RW; Smith, C; Szewczak, M; Woods, A	1
Angel, J; Barbella, Y; Israel, A; Orfila, GL; Torres, M	1
Kulkarni, SK; Sharma, A	2
Van den Buuse, M	1
Amore, M; Giordani, L; Giorgetti, G; Zazzeri, N	1
Inoue, Y; Ishida, M; Kaneko, S; Kondo, T; Mihara, K; Otani, K; Suzuki, A; Yasui, N	1
Bizot, JC	1
Fujiseki, Y; Inagaki, C; Kinoshita, T; Okugawa, G; Omori, K; Suzukawa, J	1
Besson, A; Eschalier, A; Fialip, J; Privat, AM	1
Abe, K; Hara, K; Izumi, F; Kaneko, S; Kawamura, M; Nakamura, J; Terao, T; Toyohira, Y; Ueno, S; Uezono, Y; Yanagihara, N; Yoshimura, R	1
Duman, RS; Impey, S; Sakai, N; Shin, K; Steffen, C; Storm, D; Thome, J; Zhang, YJ	1
Cassella, JV; Coverdale, S; Hoffman, DC; Kehne, JH; McCloskey, TC	1
Mitsunaga, H; Ukai, M	1
FUKUCHI, G	1
Cohen, LH; Hollembaek, J; Li, W; Penn, LD; Yu, C	1
Kahn, RS; Kemner, C; Oranje, B; Verbaten, MN	1
Hashimoto, S; Khotib, J; Miyatake, M; Nagumo, Y; Nakamachi, T; Narita, M; Sakurai, T; Shioda, S; Suzuki, T; Yanagisawa, M	1
Gerak, LR; Moerschbaecher, JM; Quinton, MS; Winsauer, PJ	1
Birkenhager, TK; Bruijn, JA; Moleman, P; Mulder, PG; van den Broek, WW	1
Lin, Y; Quartermain, D; Stone, EA	1
Balci, F; Campbell, U; Hanania, T; Olivier, BE; Paterson, NE	1
Akagawa, K; Fujiwara, T; Kofuji, T; Snada, M; Yoshikawa, T	1
Avissar, S; Golan, M; Schreiber, G	1
Chau, DT; Dawson, R; Green, AI; Khokhar, JY	1
Collins, SL; Contreras-Mora, HM; Correa, M; Errante, EL; Rowland, MA; Salamone, JD; Yohn, SE	1

Reviews

4 review(s) available for haloperidol and desipramine

Article	Year
The role of receptor binding in drug discovery. Journal of natural products, 1993, Volume: 56, Issue:4 Topics: Animals; Drug Design; Humans; Receptors, Drug	1993
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Neurotransmitter receptors in the central nervous system and aging: pharmacological aspect (review). Experimental gerontology, 1984, Volume: 19, Issue:4 Topics: Adenylyl Cyclases; Aging; Animals; Brain; Desipramine; Dopamine; Dopamine Antagonists; Female; Fluphenazine; Haloperidol; Humans; Male; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Cholinergic; Receptors, Dopamine; Receptors, GABA-A; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Serotonin; Reserpine; Scopolamine; Spiperone; Tetrahydronaphthalenes; Tissue Distribution; Tritium	1984
[Pharmacological treatment of delusional depression]. Minerva psichiatrica, 1996, Volume: 37, Issue:1 Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Delusions; Depressive Disorder; Desipramine; Drug Therapy, Combination; Haloperidol; Humans; Perphenazine; Psychotic Disorders	1996

Trials

5 trial(s) available for haloperidol and desipramine

Article	Year
Antidepressants in 'depressed' schizophrenic inpatients. A controlled trial. Archives of general psychiatry, 1989, Volume: 46, Issue:10 Topics: Adolescent; Adult; Amitriptyline; Benztropine; Clinical Trials as Topic; Depressive Disorder; Desipramine; Double-Blind Method; Drug Therapy, Combination; Female; Haloperidol; Hospitalization; Humans; Male; Middle Aged; Placebos; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology	1989
[Quantitative EEG analysis of a single dose of psychotropic drugs in healthy probands]. Psychiatrie, Neurologie, und medizinische Psychologie, 1986, Volume: 38, Issue:8 Topics: Adult; Arousal; Brain; Carbamazepine; Clomipramine; Desipramine; Diazepam; Electroencephalography; Evoked Potentials; Female; Haloperidol; Humans; Imipramine; Male; Psychotropic Drugs	1986
[Clinical experimentation with desipramine with statistical control]. Annales medico-psychologiques, 1968, Volume: 1, Issue:1 Topics: Adult; Aged; Anorexia Nervosa; Barbiturates; Bipolar Disorder; Chlordiazepoxide; Chlorpromazine; Clinical Trials as Topic; Depression; Desipramine; Diazepam; Haloperidol; Humans; Methotrimeprazine; Middle Aged; Schizophrenia	1968
No interaction between desipramine and bromperidol. Progress in neuro-psychopharmacology & biological psychiatry, 1996, Volume: 20, Issue:7 Topics: Adult; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2D6; Desipramine; Drug Interactions; Female; Haloperidol; Humans; Male; Oxidation-Reduction; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology	1996
Modulating sensorimotor gating in healthy volunteers: the effects of desipramine and haloperidol. Psychiatry research, 2004, Jul-15, Volume: 127, Issue:3 Topics: Adrenergic Uptake Inhibitors; Adult; Antipsychotic Agents; Cross-Over Studies; Desipramine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Electromyography; Habituation, Psychophysiologic; Haloperidol; Heart Rate; Humans; Inhibition, Psychological; Male; Psychomotor Performance; Reflex, Startle; Time Factors	2004

Other Studies

148 other study(ies) available for haloperidol and desipramine

Article	Year
Activity of aromatic substituted phenylpiperazines lacking affinity for dopamine binding sites in a preclinical test of antipsychotic efficacy. Journal of medicinal chemistry, 1989, Volume: 32, Issue:5 Topics: Animals; Antipsychotic Agents; Avoidance Learning; Dose-Response Relationship, Drug; Piperazines; Rats; Receptors, Dopamine; Receptors, Serotonin; Structure-Activity Relationship	1989
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
Pyrroloisoquinoline antidepressants. 2. In-depth exploration of structure-activity relationships. Journal of medicinal chemistry, 1987, Volume: 30, Issue:8 Topics: Animals; Antidepressive Agents; Blepharoptosis; Brain; Catecholamines; Chemical Phenomena; Chemistry; Dopamine; Isoquinolines; Male; Molecular Conformation; Motor Activity; Norepinephrine; Pyrroles; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Dopamine; Receptors, Serotonin; Serotonin; Structure-Activity Relationship; Synaptosomes; Tetrabenazine	1987
Functional group contributions to drug-receptor interactions. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship	1984
Synthesis and anxiolytic activity of a series of pyrazino[1,2-a][1,4]benzodiazepine derivatives. Journal of medicinal chemistry, 1980, Volume: 23, Issue:8 Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Apomorphine; Benzodiazepines; Diazepam; Guinea Pigs; Histamine Antagonists; In Vitro Techniques; Male; Norepinephrine; Pyrazines; Rats; Receptors, Drug; Serotonin	1980
Synthesis and characterization of radioiodinated N-(3-iodopropen-1-yl)-2 beta-carbomethoxy-3 beta-(4-chlorophenyl)tropanes: potential dopamine reuptake site imaging agents. Journal of medicinal chemistry, 1994, May-13, Volume: 37, Issue:10 Topics: Animals; Binding, Competitive; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Iodine Radioisotopes; Isotope Labeling; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Protein Binding; Rats; Rats, Sprague-Dawley; Stereoisomerism; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Tropanes	1994
Synthesis, evaluation, and comparative molecular field analysis of 1-phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes as ligands for histamine H(1) receptors. Journal of medicinal chemistry, 1999, Aug-12, Volume: 42, Issue:16 Topics: Animals; Binding Sites; Binding, Competitive; Brain; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ligands; Models, Molecular; Pyrilamine; Radioligand Assay; Structure-Activity Relationship; Tetrahydronaphthalenes	1999
Predicting blood-brain barrier permeation from three-dimensional molecular structure. Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11 Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs. The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:3 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations	2002
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship	2003
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies. Biochemical and biophysical research communications, 2004, Mar-19, Volume: 315, Issue:4 Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Detergents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Humans; Ivermectin; Mice; NIH 3T3 Cells; Substrate Specificity	2004
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9 Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water	2005
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors. Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11 Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated	2005
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Support vector machines classification of hERG liabilities based on atom types. Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11 Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Molecular properties of psychopharmacological drugs determining non-competitive inhibition of 5-HT3A receptors. European journal of medicinal chemistry, 2009, Volume: 44, Issue:6 Topics: Binding Sites; Computer Simulation; Databases, Factual; Models, Chemical; Models, Molecular; Molecular Structure; Molecular Weight; Psychotropic Drugs; Serotonin 5-HT3 Receptor Antagonists; Structure-Activity Relationship	2009
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs. Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Side chain flexibilities in the human ether-a-go-go related gene potassium channel (hERG) together with matched-pair binding studies suggest a new binding mode for channel blockers. Journal of medicinal chemistry, 2009, Jul-23, Volume: 52, Issue:14 Topics: Binding Sites; Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Potassium Channel Blockers; Protein Binding; Protein Conformation	2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model. European journal of medicinal chemistry, 2011, Volume: 46, Issue:2 Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship	2011
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk. Cardiovascular research, 2011, Jul-01, Volume: 91, Issue:1 Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1 Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity	2013
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells. Bioorganic & medicinal chemistry letters, 2013, Mar-15, Volume: 23, Issue:6 Topics: Amides; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Neoplastic Stem Cells; Small Molecule Libraries; Structure-Activity Relationship	2013
Which metabolites circulate? Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:5 Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
The synthesis and comparative receptor binding affinities of novel, isomeric pyridoindolobenzazepine scaffolds. Bioorganic & medicinal chemistry letters, 2014, Jan-15, Volume: 24, Issue:2 Topics: Benzodiazepinones; Isomerism; Protein Binding; Protein Structure, Tertiary; Receptors, Cell Surface	2014
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
Non-carboxylic acid inhibitors of aldose reductase based on N-substituted thiazolidinedione derivatives. European journal of medicinal chemistry, 2021, Nov-05, Volume: 223 Topics: Aldehyde Reductase; Animals; Caco-2 Cells; Catalytic Domain; Dogs; Enzyme Inhibitors; Humans; Hypoglycemic Agents; Madin Darby Canine Kidney Cells; Male; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Protein Binding; Rats, Wistar; Structure-Activity Relationship; Thiazolidinediones	2021
Changes in the conditiond avoidance behaviour of rats following the administration of drugs to the amygdala [proceedings]. The Journal of pharmacy and pharmacology, 1976, Volume: 28 Suppl Topics: Amygdala; Animals; Apomorphine; Avoidance Learning; Benztropine; Conditioning, Psychological; Desipramine; Dextroamphetamine; Haloperidol; Male; Rats	1976
The role of dopaminergic systems in gamma-hydroxybutyrate-induced electrocorticogram hypersynchronization in the rat. The Journal of pharmacy and pharmacology, 1977, Volume: 29, Issue:10 Topics: Amphetamine; Animals; Behavior, Animal; Cortical Synchronization; Desipramine; Dopamine; Electroencephalography; Haloperidol; Hydroxybutyrates; Male; Piribedil; Rats; Receptors, Dopamine	1977
Amfonelic acid, a non-amphetamine stimulant, has marked effects on brain dopamine metabolism but not noradrenaline metabolism: association with differences in neuronal storage systems. The Journal of pharmacy and pharmacology, 1978, Volume: 30, Issue:7 Topics: Animals; Brain; Central Nervous System; Desipramine; Dopamine; Female; Haloperidol; Methyltyrosines; Nalidixic Acid; Naphthyridines; Neurons; Norepinephrine; Phenoxybenzamine; Propranolol; Rats; Tyrosine 3-Monooxygenase	1978
Tricyclic antidepressants and histamine H1 receptors. Mayo Clinic proceedings, 1979, Volume: 54, Issue:10 Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Atropine; Benztropine; Cells, Cultured; Clozapine; Cyproheptadine; Desipramine; Doxepin; Haloperidol; Histamine H1 Antagonists; Hydroxyzine; Imipramine; Mice; Neoplasms, Experimental; Neuroblastoma; Nortriptyline; Protriptyline; Receptors, Histamine; Receptors, Histamine H1; Receptors, Muscarinic	1979
Effect of centrally active drugs on dopamine oxidation by rat brain catecholamine oxidase. Experientia, 1979, Dec-15, Volume: 35, Issue:12 Topics: Animals; Antipsychotic Agents; Brain; Chlorpromazine; Desipramine; Dopamine; Dopamine beta-Hydroxylase; Female; Haloperidol; Imipramine; Kinetics; Promazine; Rats; Thioridazine; Trifluoperazine; Trifluperidol	1979
[Effect of psychotropic drugs on somatosensory evoked cortical potentials]. Acta biologica et medica Germanica, 1979, Volume: 38, Issue:4 Topics: Animals; Anti-Anxiety Agents; Desipramine; Diazepam; Evoked Potentials; Female; Haloperidol; Hexobarbital; Medazepam; Piperidines; Rats; Somatosensory Cortex	1979
Analysis of presynaptic inhibitory actions of various dopamine analogs on sympathetic neurotransmission in mongrel dogs. Life sciences, 1977, Feb-01, Volume: 20, Issue:3 Topics: Animals; Blood Pressure; Deoxyepinephrine; Desipramine; Dogs; Dopamine; Female; Haloperidol; Heart; Heart Rate; Male; Neural Inhibition; Phentolamine; Propranolol; Receptors, Adrenergic, alpha; Receptors, Dopamine; Sympathetic Nervous System; Synaptic Transmission	1977
Plasma corticosterone and brain catecholamines in stress: effect of psychotropic drugs. Pharmacology, biochemistry, and behavior, 1977, Volume: 6, Issue:1 Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Brain Chemistry; Catecholamines; Chlorpromazine; Corticosterone; Desipramine; Diazepam; Dopamine; Haloperidol; Hypothalamus; In Vitro Techniques; Male; Norepinephrine; Pargyline; Phenobarbital; Prohibitins; Psychotropic Drugs; Rats; Stress, Physiological; Telencephalon	1977
Effects of several catecholamines on sympathetic transmission to the myocardium: role of presynaptic alpha-adrenoceptors. European journal of pharmacology, 1977, Apr-07, Volume: 42, Issue:3 Topics: Animals; Catecholamines; Desipramine; Dogs; Drug Interactions; Electric Stimulation; Female; Haloperidol; Heart; Heart Rate; Male; Phentolamine; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Synaptic Transmission	1977
Analysis of the cardiac stimulant properties of (3,4-dihydroxyphenyl)-cyclopropylamine (ASL-7003) and 2-amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene (A6,7DTN). The Journal of pharmacology and experimental therapeutics, 1979, Volume: 210, Issue:2 Topics: Animals; Cyclopropanes; Desipramine; Dogs; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Female; Guinea Pigs; Haloperidol; Heart; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Naphthols; Phentolamine; Receptors, Adrenergic, beta; Tetrahydronaphthalenes	1979
Free 3-methoxy-4-hydroxyphenylethyleneglycol in the central nervous system of the rat: semi-automated fluorometric assay, turnover and effects of drugs. Journal of neurochemistry, 1979, Volume: 32, Issue:6 Topics: 3-Methoxy-4-hydroxyphenylethanol; Animals; Autoanalysis; Brain; Catechols; Chromatography, Gas; Desipramine; Female; Haloperidol; Hydroxydopamines; Male; Mass Spectrometry; Phenoxybenzamine; Rats; Reserpine; Spectrometry, Fluorescence; Spinal Cord; Structure-Activity Relationship	1979
Electrophysiological and biochemical responses of noradrenergic neurons to a non-amphetamine CNS stimulant. Brain research, 1979, Apr-27, Volume: 166, Issue:2 Topics: Animals; Desipramine; Dextroamphetamine; Evoked Potentials; Female; Haloperidol; Hindlimb; Locus Coeruleus; Mechanoreceptors; Methoxyhydroxyphenylglycol; Naphthyridines; Neurons; Norepinephrine; Rats; Receptors, Adrenergic; Receptors, Dopamine	1979
Effects of embryonic and neonatal disruption of developing central dopaminergic systems. Applied neurophysiology, 1979, Volume: 42, Issue:1-2 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Corpus Striatum; Desipramine; Dopamine; Haloperidol; Hydroxydopamines; Locomotion; Methyltyrosines; Rats	1979
Theoretical and methodological considerations on drug discrimination learning. Psychopharmacologia, 1976, Mar-16, Volume: 46, Issue:2 Topics: Amphetamine; Animals; Chlordiazepoxide; Cues; Desipramine; Discrimination Learning; Generalization, Stimulus; Haloperidol; Male; Psychotropic Drugs; Rats; Rats, Inbred Strains; Reinforcement Schedule	1976
Studies on the hypotensive action of alpha-methyldopamine. British journal of pharmacology, 1975, Volume: 54, Issue:4 Topics: Animals; Blood Pressure; Cats; Deoxyepinephrine; Depression, Chemical; Desipramine; Dopamine; Drug Interactions; Electric Stimulation; Female; Haloperidol; Hypertension; Male; Nordefrin; Norepinephrine; Phentolamine; Rats; Reticular Formation; Time Factors	1975
Inhibition of prostaglandin synthetase by psychotropic drugs. Experientia, 1975, Mar-15, Volume: 31, Issue:3 Topics: Amitriptyline; Animals; Anthracenes; Antidepressive Agents; Arachidonic Acids; Cattle; Chlorpromazine; Clomipramine; Desipramine; Enzyme Inhibitors; Haloperidol; Imipramine; Male; Mixed Function Oxygenases; Prostaglandins; Psychotropic Drugs; Seminal Vesicles	1975
Pharmacological specificity of the increase in neurotensin concentrations after antipsychotic drug treatment. Brain research, 1992, Mar-20, Volume: 575, Issue:2 Topics: Animals; Antipsychotic Agents; Brain Chemistry; Chlordiazepoxide; Desipramine; Diphenhydramine; Haloperidol; Male; Neurotensin; Rats; Rats, Inbred Strains	1992
Effect of antidepressant drugs on monoamine synthesis in brain in vivo. Neuropharmacology, 1992, Volume: 31, Issue:7 Topics: Animals; Antidepressive Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Citalopram; Clorgyline; Cyclopropanes; Desipramine; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Haloperidol; Hydrazines; Imipramine; Male; Milnacipran; Norepinephrine; Organ Specificity; Parietal Lobe; Rats; Rats, Wistar; Serotonin; Tyrosine 3-Monooxygenase	1992
Heterologous monoamine reuptake: lack of transmitter specificity of neuron-specific carriers. Neurochemistry international, 1992, Volume: 20 Suppl Topics: Animals; Biogenic Monoamines; Carrier Proteins; Caudate Nucleus; Desipramine; Dopamine; Haloperidol; Male; Neurons; Neurotransmitter Agents; Neurotransmitter Uptake Inhibitors; Piperazines; Prefrontal Cortex; Rats; Rats, Sprague-Dawley	1992
Adipose tissue distribution and chemical structure of basic lipophilic drugs: desipramine, N-acetyl desipramine, and haloperidol. Pharmacology & toxicology, 1992, Volume: 70, Issue:2 Topics: Adipose Tissue; Administration, Oral; Animals; Desipramine; Haloperidol; Injections, Intravenous; Male; Rats; Rats, Inbred Strains; Tissue Distribution	1992
Tardive dyskinesia in the elderly patient. Hospital practice (Office ed.), 1992, Apr-15, Volume: 27, Issue:4 Topics: Aged; Chlorpromazine; Chronic Disease; Clonazepam; Clozapine; Depressive Disorder; Desipramine; Diphenhydramine; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Neurologic Examination	1992
Amphetamine sensitization and amygdala kindling: pharmacological evaluation of catecholaminergic and cholinergic mechanisms. Brain research bulletin, 1991, Volume: 26, Issue:3 Topics: Acetylcholine; Adenylyl Cyclase Inhibitors; Amphetamine; Amygdala; Animals; Behavior, Animal; Catecholamines; Desipramine; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Kindling, Neurologic; Male; Norepinephrine; Parasympathetic Nervous System; Rats; Rats, Inbred Strains; Scopolamine; Stereotaxic Techniques; Synaptic Transmission	1991
Effects of serotonergic agents on isolation-induced aggression. Pharmacology, biochemistry, and behavior, 1991, Volume: 39, Issue:3 Topics: Aggression; Animals; Anti-Anxiety Agents; Benzamides; Benzodiazepines; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Desipramine; Haloperidol; Male; Mice; Postural Balance; Ritanserin; Serotonin; Serotonin Antagonists; Social Isolation	1991
Inhibition of neurotensin-induced miosis by blockade of ocular dopamine pathways. Journal of ocular pharmacology, 1990,Spring, Volume: 6, Issue:1 Topics: Animals; Atropine; Autonomic Nervous System; Desipramine; Dopamine; Dopamine Antagonists; Eye; Haloperidol; Hydroxydopamines; Iris; Miosis; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Nerve Endings; Neurotensin; Neurotransmitter Agents; Oxidopamine; Rabbits; Receptors, Opioid, mu	1990
Desipramine and nortriptyline antagonize apomorphine and reserpine hypothermia by a different mechanism. The Journal of pharmacy and pharmacology, 1990, Volume: 42, Issue:8 Topics: Animals; Apomorphine; Body Temperature; Desipramine; Haloperidol; Hypothermia; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Nortriptyline; Reserpine	1990
Blockade of the noradrenaline carrier increases extracellular dopamine concentrations in the prefrontal cortex: evidence that dopamine is taken up in vivo by noradrenergic terminals. Journal of neurochemistry, 1990, Volume: 55, Issue:3 Topics: Animals; Caudate Nucleus; Desipramine; Dopamine; Drug Synergism; Extracellular Space; Frontal Lobe; Haloperidol; Hydroxydopamines; Male; Maprotiline; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Strains	1990
Differential effects of psychotropic drugs on feeding in rats: is histamine blockade involved? Pharmacology, biochemistry, and behavior, 1990, Volume: 36, Issue:4 Topics: Animals; Desipramine; Diet; Doxepin; Drinking; Eating; Haloperidol; Histamine Antagonists; Male; Promazine; Psychotropic Drugs; Rats; Rats, Inbred Strains	1990
Do both adrenaline and noradrenaline stimulate cardiac alpha-adrenoceptors to induce positive inotropy of rat atria? British journal of pharmacology, 1989, Volume: 98, Issue:2 Topics: Animals; Cocaine; Desipramine; Dibenzylchlorethamine; Epinephrine; Haloperidol; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Norepinephrine; Pindolol; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stimulation, Chemical; Timolol	1989
Differential effects of dopaminergic drugs on open-field behavior of spontaneously hypertensive rats and normotensive Wistar-Kyoto rats. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:3 Topics: Amphetamine; Animals; Apomorphine; Benzazepines; Clonidine; Desipramine; Dopamine; Dopamine Agents; Haloperidol; Hypertension; Male; Motor Activity; Piperazines; Rats; Rats, Inbred SHR; Rats, Inbred WKY	1989
Effects of centrally acting beta adrenergic agonists on discrete trial conditioned avoidance behavior in rats. Psychopharmacology, 1989, Volume: 97, Issue:1 Topics: Adrenergic beta-Agonists; Animals; Avoidance Learning; Desipramine; Haloperidol; Male; Propranolol; Rats; Rats, Inbred Strains	1989
Serum haloperidol and desipramine concentrations and the treatment of psychotic depression: two case reports. The Journal of nervous and mental disease, 1989, Volume: 177, Issue:7 Topics: Adult; Depressive Disorder; Desipramine; Female; Haloperidol; Humans	1989
Effects of corticotropin releasing factor, desipramine and haloperidol on a DRL schedule of reinforcement. Pharmacology, biochemistry, and behavior, 1989, Volume: 32, Issue:4 Topics: Amphetamine; Animals; Behavior, Animal; Conditioning, Operant; Corticotropin-Releasing Hormone; Desipramine; Dose-Response Relationship, Drug; Evaluation Studies as Topic; Haloperidol; Male; Rats; Rats, Inbred Strains; Reinforcement Schedule	1989
Discriminative stimulus properties of clenbuterol: evidence for beta adrenergic involvement. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:1 Topics: Albuterol; Amphetamine; Animals; Chlorpromazine; Clenbuterol; Desipramine; Discrimination Learning; Dose-Response Relationship, Drug; Ethanolamines; Haloperidol; Isomerism; Male; Pentylenetetrazole; Prenalterol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta	1988
The paw test: a behavioural paradigm for differentiating between classical and atypical neuroleptic drugs. Psychopharmacology, 1987, Volume: 93, Issue:3 Topics: Animals; Antipsychotic Agents; Chlorpromazine; Clozapine; Desipramine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Forelimb; Haloperidol; Hindlimb; Male; Metoclopramide; Morphine; Motor Activity; Rats; Rats, Inbred Strains; Thioridazine	1987
Behavioral effects of histamine H1 antagonists: comparison with other drugs and modification by haloperidol. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:2 Topics: Animals; Bupropion; Cocaine; Conditioning, Operant; Cyproheptadine; Desipramine; Diazepam; Dose-Response Relationship, Drug; Electroshock; Haloperidol; Histamine H1 Antagonists; Male; Propiophenones; Saimiri	1988
Dopaminergic modulation of ACTH-induced grooming. European journal of pharmacology, 1986, Jan-29, Volume: 120, Issue:3 Topics: Adrenocorticotropic Hormone; Animals; Apomorphine; Catheterization; Desipramine; Ergotamine; Grooming; Haloperidol; Male; Nucleus Accumbens; Oxymetazoline; Periaqueductal Gray; Phentolamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Substantia Nigra	1986
Chronic antidepressant treatment and mouse brain 3H-imipramine binding. Journal of neuroscience research, 1986, Volume: 16, Issue:2 Topics: Animals; Antidepressive Agents; Binding Sites; Cerebral Cortex; Desipramine; Haloperidol; Imipramine; Male; Mice; Mice, Inbred C57BL; Receptors, Adrenergic, beta; Receptors, Dopamine; Receptors, Dopamine D2; Selegiline	1986
Noradrenergic involvement in catalepsy induced by delta 9-tetrahydrocannabinol. Neuropharmacology, 1987, Volume: 26, Issue:1 Topics: Animals; Brain; Catalepsy; Desipramine; Dopamine; Dronabinol; Haloperidol; Hydroxydopamines; Locus Coeruleus; Male; Norepinephrine; Oxidopamine; Rats; Serotonin	1987
A grand mal seizure associated with desipramine and haloperidol. Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1987, Volume: 32, Issue:6 Topics: Adult; Desipramine; Drug Interactions; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Female; Haloperidol; Humans	1987
A grand mal seizure associated with desipramine and haloperidol. Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1988, Volume: 33, Issue:1 Topics: Desipramine; Drug Synergism; Electrocardiography; Epilepsy, Tonic-Clonic; Haloperidol; Humans	1988
Ultrasonic vocalization in response to unavoidable aversive stimuli in rats: effects of benzodiazepines. Life sciences, 1988, Volume: 43, Issue:6 Topics: Alprazolam; Animals; Benzodiazepines; Desipramine; Diazepam; Electroshock; Flumazenil; Haloperidol; Male; Rats; Rats, Inbred Strains; Ultrasonics; Vocalization, Animal	1988
Dopamine autoreceptors modulate dopamine release from the prefrontal cortex. Journal of neurochemistry, 1986, Volume: 47, Issue:3 Topics: Animals; Apomorphine; Calcium; Desipramine; Dopamine; Electric Stimulation; Ergolines; Female; Frontal Lobe; Haloperidol; Male; Nomifensine; Quinpirole; Rabbits; Receptors, Dopamine	1986
Desipramine induces yawning behaviour in rats. Neuropharmacology, 1986, Volume: 25, Issue:7 Topics: Animals; Antidepressive Agents; Desipramine; Drug Interactions; Haloperidol; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reflex; Scopolamine	1986
Neuroleptic dose and desipramine concentrations during combined treatment of unipolar delusional depression. The American journal of psychiatry, 1986, Volume: 143, Issue:9 Topics: Administration, Oral; Adult; Aged; Delusions; Depressive Disorder; Desipramine; Drug Administration Schedule; Drug Therapy, Combination; Female; Haloperidol; Humans; Male; Middle Aged; Outcome and Process Assessment, Health Care; Perphenazine; Psychiatric Status Rating Scales	1986
Bromocriptine potentiates the behavioural effects of directly and indirectly acting dopamine receptor agonists in mice. Naunyn-Schmiedeberg's archives of pharmacology, 1985, Volume: 331, Issue:1 Topics: alpha-Methyltyrosine; Animals; Bromocriptine; Desipramine; Drug Synergism; Fluoxetine; Haloperidol; Levodopa; Male; Methyltyrosines; Mice; Motor Activity; Nomifensine; Receptors, Dopamine; Reserpine	1985
Place preference conditioning with methylphenidate and nomifensine. Brain research, 1985, Apr-15, Volume: 332, Issue:1 Topics: Animals; Catecholamines; Central Nervous System; Desipramine; Dopamine; Drug Interactions; Haloperidol; Hydroxydopamines; Isoquinolines; Male; Methylphenidate; Motor Activity; Nomifensine; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Strains; Spatial Behavior	1985
Implications of dopamine agonist-induced hypothermia following increased density of dopamine receptors in the mouse. Neuropharmacology, 1985, Volume: 24, Issue:8 Topics: Animals; Apomorphine; Body Temperature; Desipramine; Dopamine; Haloperidol; Hydroxydopamines; Kinetics; Mice; Motor Activity; Oxidopamine; Receptors, Dopamine	1985
Behavioral treatment in two cases of obsessive-compulsive disorder with concomitant bipolar affective disorder. The American journal of psychiatry, 1985, Volume: 142, Issue:3 Topics: Adult; Behavior Therapy; Bipolar Disorder; Desipramine; Female; Haloperidol; Humans; Lithium; Male; Middle Aged; Obsessive-Compulsive Disorder	1985
Uptake and/or binding of tricyclic antidepressants in human red cells. Life sciences, 1985, May-06, Volume: 36, Issue:18 Topics: Buffers; Cations, Monovalent; Desipramine; Erythrocyte Membrane; Erythrocytes; Haloperidol; Humans; Hydrogen-Ion Concentration; Imipramine; In Vitro Techniques; Kinetics; Orosomucoid; Osmolar Concentration; Plasma; Protein Binding; Serum Albumin; Trifluoperazine	1985
The cardiovascular effects of intraventricular clonidine and Bay 1470 in conscious hypertensive cats. British journal of pharmacology, 1974, Volume: 52, Issue:3 Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cats; Clonidine; Desipramine; Dioxanes; Dopamine Antagonists; Haloperidol; Heart Rate; Hemodynamics; Hypertension, Renal; Phentolamine; Piperidines; Thiazines; Time Factors; Xylazine	1974
Effect of psychotropic drugs on phosphodiesterase and cyclic AMP level in rat brain in vivo. Brain research, 1973, Dec-07, Volume: 63 Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Chlorpromazine; Chlorprothixene; Cyclic AMP; Desipramine; Haloperidol; Imipramine; Male; Phosphoric Diester Hydrolases; Rats; Theophylline; Tranquilizing Agents; Triflupromazine; Tritium	1973
Uptake of the putative neurotransmitter, glycine, into the rabbit retina. Investigative ophthalmology, 1972, Volume: 11, Issue:4 Topics: Alanine; Aminobutyrates; Animals; Aspartic Acid; Desipramine; Diazepam; Dinitrophenols; Glutamates; Glutethimide; Glycine; Haloperidol; Lysine; Meprobamate; Neurons; Neurotransmitter Agents; Ouabain; Phenytoin; Rabbits; Retina; Synaptic Transmission; Temperature	1972
Effect of central stimulants and depressants on mouse brain acetylcholine and choline levels. European journal of pharmacology, 1972, Volume: 18, Issue:2 Topics: Acetylcholine; Amphetamine; Animals; Atropine; Brain Chemistry; Central Nervous System Stimulants; Chlorpromazine; Choline; Depression, Chemical; Desipramine; Diazepam; Haloperidol; Ketones; Male; Mice; Pentobarbital; Pentylenetetrazole; Physostigmine; Reserpine; Stimulation, Chemical; Tranquilizing Agents; Tremorine	1972
Effects of dopamine on the conductance of perfused vascular beds of the chloralosed cat. British journal of pharmacology, 1972, Volume: 44, Issue:3 Topics: Animals; Atropine; Blood Pressure; Blood Vessels; Cats; Cocaine; Constriction; Desipramine; Dilatation; Dopamine; Dopamine Antagonists; Drug Synergism; Female; Haloperidol; Heart Rate; Hindlimb; Histamine H1 Antagonists; Isoproterenol; Male; Perfusion; Phenoxybenzamine; Propranolol; Receptors, Adrenergic; Vascular Resistance	1972
Hypothermic effect of apomorphine in the mouse. The Journal of pharmacy and pharmacology, 1972, Volume: 24, Issue:9 Topics: Amines; Animals; Apomorphine; Atropine; Body Temperature; Depression, Chemical; Desipramine; Dibenzazepines; Dibenzocycloheptenes; Haloperidol; Male; Mice; Phenoxybenzamine; Pimozide; Receptors, Drug	1972
Dopamine receptor in the reward system of the rat. Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 209, Issue:2 Topics: Amantadine; Animals; Apomorphine; Benzyl Compounds; Cortical Synchronization; Desipramine; Dihydroxyphenylalanine; Dopamine; Electrodes, Implanted; Electroencephalography; Haloperidol; Hydrazines; Hypothalamus; Levodopa; Male; Rats; Receptors, Drug; Reward; Self Stimulation; Time Factors	1974
[Analysis of the monoaminergic mechanisms of the dorsal hippocampus actualizing conditioned avoidance reactions in rats]. Biulleten' eksperimental'noi biologii i meditsiny, 1974, Volume: 78, Issue:11 Topics: Animals; Avoidance Learning; Chlorpromazine; Conditioning, Classical; Depression, Chemical; Desipramine; Dihydroergotamine; Dopamine; Drug Interactions; Haloperidol; Hippocampus; Imipramine; Male; Motor Activity; Muscle Tonus; Norepinephrine; Perphenazine; Phentolamine; Rats; Reaction Time; Serotonin	1974
The effect of p-chloroamphetamine on motility in rats after inhibition of monoamine synthesis, storage, uptake and receptor interaction. Psychopharmacologia, 1974, Jan-14, Volume: 34, Issue:3 Topics: Amitriptyline; Amphetamine; Animals; Biogenic Amines; Catecholamines; Chlorine; Chlorpheniramine; Chlorpromazine; Desipramine; Dibenzazepines; Dose-Response Relationship, Drug; Doxepin; Female; Haloperidol; Imipramine; Methyltyrosines; Motor Activity; Rats; Receptors, Cholinergic; Serotonin Antagonists; Spiro Compounds; Time Factors	1974
Possible role of free serum tryptophan in the control of brain tryptophan level and serotonin synthesis. Advances in biochemical psychopharmacology, 1974, Volume: 11, Issue:0 Topics: Amino Acids; Animals; Apomorphine; Blood-Brain Barrier; Brain; Chlorpromazine; Cold Temperature; Desipramine; Fenfluramine; Haloperidol; Hydroxyindoleacetic Acid; Kinetics; Methyltyrosines; Morphine; Neurons; Phenelzine; Protein Binding; Rats; Serotonin; Stimulation, Chemical; Tryptophan; Tryptophan Hydroxylase	1974
Effect of apomorphine on motility in rats. European journal of pharmacology, 1972, Volume: 17, Issue:2 Topics: Animals; Apomorphine; Behavior, Animal; Benzoates; Benzyl Compounds; Brain Chemistry; Catecholamines; Cocaine; Desipramine; Dihydroxyphenylalanine; Disulfiram; Drug Antagonism; Esters; Fluorine; Haloperidol; Hydrazines; Male; Motor Activity; Nialamide; Nortriptyline; Phenoxybenzamine; Rats; Rats, Inbred Strains; Reserpine; Serine; Spiro Compounds; Stimulation, Chemical; Thiocarbamates; Tranquilizing Agents; Tyrosine	1972
Detection of some psychotherapeutic drugs and their metabolites in urine. Clinical toxicology, 1971, Volume: 4, Issue:2 Topics: Amitriptyline; Amphetamine; Analgesics; Antidepressive Agents; Chlordiazepoxide; Chlorpromazine; Chromatography, Thin Layer; Desipramine; Diazepam; Fluphenazine; Haloperidol; Humans; Imipramine; Indicators and Reagents; Methadone; Perphenazine; Solvents; Thioridazine; Tranquilizing Agents; Trifluoperazine	1971
GABA uptake in rat central nervous system: comparison of uptake in slices and homogenates and the effects of some inhibitors. Journal of neurochemistry, 1971, Volume: 18, Issue:10 Topics: Aminobutyrates; Animals; Caproates; Carnitine; Centrifugation, Density Gradient; Cerebellum; Cerebral Cortex; Chlorpromazine; Cysteamine; Desipramine; Dithiothreitol; Ethylmaleimide; Haloperidol; Hippocampus; Imipramine; Ornithine; Pimelic Acids; Propionates; Rats; Spinal Cord; Sulfanilamides; Synaptic Vesicles; Taurine; Tritium; Valerates	1971
Studies of the influence of some psychotropic substances on the grooming behaviour of white mice. Psychopharmacologia, 1969, Volume: 14, Issue:1 Topics: Amitriptyline; Animals; Aspirin; Charcoal; Chlordiazepoxide; Chlorpromazine; Desipramine; Dextroamphetamine; Female; Grooming; Haloperidol; Imipramine; Iproniazid; Metronidazole; Mice; Nortriptyline; Psychopharmacology	1969
Haloperidol-desipramine interaction in mice, rats and man. Chemico-biological interactions, 1970, Volume: 2, Issue:2 Topics: Animals; Basal Ganglia Diseases; Benperidol; Butyrophenones; Chronic Disease; Desipramine; Drug Antagonism; Female; Haloperidol; Humans; Kinetics; Male; Mice; Middle Aged; Motor Activity; Muscles; Orphenadrine; Psychotic Disorders; Rats; Tremor	1970
Influence of drugs on catecholamine metabolism in brain as studied by 14C-tyrosine. British journal of pharmacology, 1968, Volume: 34, Issue:1 Topics: Animals; Brain; Carbon Isotopes; Catecholamines; Chlorpromazine; Desipramine; Dopamine; Haloperidol; Mice; Norepinephrine; Promethazine; Rats; Stimulation, Chemical; Tyrosine	1968
Studies of the influence of some psychotropic substances on the grooming behaviour of white mice. British journal of pharmacology, 1968, Volume: 34, Issue:1 Topics: Amitriptyline; Animals; Aspirin; Charcoal; Chlordiazepoxide; Chlorpromazine; Desipramine; Dextroamphetamine; Grooming; Haloperidol; Imipramine; Iproniazid; Metronidazole; Mice; Nortriptyline; Sodium Chloride; Solvents; Tranquilizing Agents	1968
Accumulation and disappearance of catecholamines formed from tyrosine-14C in mouse brain; effect of some psychotropic drugs. European journal of pharmacology, 1968, Volume: 4, Issue:4 Topics: Animals; Brain Chemistry; Carbon Isotopes; Catecholamines; Chlorpromazine; Desipramine; Dopamine; Haloperidol; Injections, Intravenous; Mice; Norepinephrine; Promethazine; Tyrosine	1968
A two-year clinical experience with lithium. Canadian Psychiatric Association journal, 1968, Volume: 13, Issue:6 Topics: Adult; Bipolar Disorder; Desipramine; Female; Follow-Up Studies; Haloperidol; Humans; Lithium; Male; Middle Aged; Outpatient Clinics, Hospital; Residential Treatment	1968
[The influence of psychopharmacologic agents on visual evoked potentials in the cat]. Vision research, 1969, Volume: 9, Issue:4 Topics: Amitriptyline; Animals; Cats; Cerebral Cortex; Chlorpromazine; Chlorprothixene; Desipramine; Diazepam; Evoked Potentials; Haloperidol; Tranquilizing Agents; Vision, Ocular; Visual Cortex	1969
Effect of neuroleptics and tricyclic antidepressants upon d-amphetamine discrimination. Pharmacology, biochemistry, and behavior, 1980, Volume: 12, Issue:1 Topics: Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Chlorpromazine; Clozapine; Desipramine; Dextroamphetamine; Discrimination, Psychological; Dose-Response Relationship, Drug; Fluphenazine; Haloperidol; Imipramine; Male; Nortriptyline; Promethazine; Rats; Sodium Chloride; Thioridazine; Trifluoperazine	1980
Neuronal responses of the globus pallidus to systemic administration of d-amphetamine: investigation of the involvement of dopamine, norepinephrine, and serotonin. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1981, Volume: 1, Issue:3 Topics: alpha-Methyltyrosine; Animals; Clonidine; Desipramine; Dextroamphetamine; Dopamine; Dose-Response Relationship, Drug; Drug Antagonism; Globus Pallidus; Haloperidol; Male; Methyltyrosines; Neurons; Norepinephrine; Rats; Serotonin; Tyrosine 3-Monooxygenase	1981
Effect of repeated treatment with desipramine in the behavioral "despair" test in rats: antagonism by "atypical" but not "classical" neuroleptics or antiadrenergic drugs. Life sciences, 1984, Mar-19, Volume: 34, Issue:12 Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Butyrophenones; Chlorpromazine; Clonidine; Clozapine; Depressive Disorder; Desipramine; Dibenzazepines; Haloperidol; Humans; Male; Metoclopramide; Phentolamine; Prazosin; Propranolol; Rats; Sulpiride	1984
Antidepressant versus neuroleptic activities of sulpiride isomers on four animal models of depression. Psychopharmacology, 1984, Volume: 83, Issue:1 Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Apomorphine; Behavior, Animal; Body Temperature; Depressive Disorder; Desipramine; Haloperidol; Helplessness, Learned; Humans; Hypnotics and Sedatives; Male; Rats; Rats, Inbred Strains; Stereoisomerism; Sulpiride	1984
Presence, distribution and pharmacology of conjugated catecholamines in the rat spinal cord. Brain research, 1983, Jan-24, Volume: 259, Issue:2 Topics: Animals; Biotransformation; Desipramine; Dextroamphetamine; Dopamine; Ganglia, Spinal; Haloperidol; Hypothalamus; Male; Norepinephrine; Rats; Rats, Inbred Strains; Spinal Cord; Synaptic Transmission	1983
Selective neonatal depletion of dopamine has no effect on medial prefrontal cortex self-stimulation in the rat. Neuroscience research, 1984, Volume: 1, Issue:5 Topics: Animals; Animals, Newborn; Apomorphine; Brain Chemistry; Catecholamines; Cerebral Cortex; Desipramine; Dopamine; Electric Stimulation; Haloperidol; Histocytochemistry; Hydroxydopamines; Injections, Intraventricular; Male; Oxidopamine; Rats; Rats, Inbred Strains; Self Stimulation	1984
Catecholamine metabolism in the rat locus coeruleus as studied by in vivo differential pulse voltammetry. II. Pharmacological and behavioral study. Brain research, 1983, Aug-29, Volume: 273, Issue:2 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catecholamines; Clonidine; Desipramine; Haloperidol; Locus Coeruleus; Male; Methoxyhydroxyphenylglycol; Piperoxan; Rats; Reserpine; Stress, Physiological	1983
Effects of catecholamine agonist and antagonist drugs on acute stomach ulceration induced by medial hypothalamic lesions in rats. Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:5 Topics: Amphetamine; Animals; Catecholamines; Chlorpromazine; Clozapine; Desipramine; Haloperidol; Hypothalamus, Middle; Isoproterenol; Male; Pargyline; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Stomach Ulcer	1983
Pharmacological investigation on the role of dopamine in the rat locus coeruleus. Neuroscience letters, 1982, Jun-30, Volume: 30, Issue:3 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Desipramine; Dopamine; Haloperidol; Hydroxydopamines; Locus Coeruleus; Male; Norepinephrine; Oxidopamine; Pargyline; Phenylacetates; Rats; Rats, Inbred Strains	1982
The locus coeruleus: actions of psychoactive drugs. Experientia, 1983, Mar-15, Volume: 39, Issue:3 Topics: Action Potentials; Animals; Atropine; Caffeine; Chlorpromazine; Desipramine; Haloperidol; Locus Coeruleus; Male; Neurons; Nicotine; Norepinephrine; Physostigmine; Psychotropic Drugs; Rats; Scopolamine	1983
Effect of psychotrophic drugs on [14C]tryptophan metabolism in cultured rat pineal gland. Biochemical pharmacology, 1983, Jul-15, Volume: 32, Issue:14 Topics: Animals; Cells, Cultured; Chlorpromazine; Desipramine; Haloperidol; Male; Melatonin; Norepinephrine; Phenothiazines; Pineal Gland; Psychotropic Drugs; Rats; Serotonin; Tryptophan	1983
Clinical conferences: Management of depression in older people. Journal of the American Geriatrics Society, 1982, Volume: 30, Issue:3 Topics: Aged; Antidepressive Agents; Dementia; Depressive Disorder; Desipramine; Diagnosis, Differential; Dose-Response Relationship, Drug; Female; Haloperidol; Hospitalization; Humans; Male; Middle Aged; Psychotic Disorders	1982
Inhibition of foot intake in the rat. Neurochemical research, 1982, Volume: 7, Issue:3 Topics: Animals; Antidepressive Agents; Appetite Depressants; Desipramine; Diazepam; Eating; Haloperidol; Imipramine; Male; Nomifensine; Rats; Rats, Inbred Strains	1982
Selective serotonin re-uptake inhibitors decrease schedule-induced polydipsia in rats: a potential model for obsessive compulsive disorder. Psychopharmacology, 1993, Volume: 112, Issue:2-3 Topics: Animals; Clomipramine; Conditioning, Operant; Desipramine; Diazepam; Disease Models, Animal; Drinking Behavior; Fluoxetine; Haloperidol; Male; Obsessive-Compulsive Disorder; Rats; Rats, Wistar; Reinforcement Schedule; Selective Serotonin Reuptake Inhibitors	1993
Evidence for a dopaminergic involvement in the renal action of centrally administered JA116a, a novel compound with possible dopaminergic activity, in rats. The Journal of pharmacy and pharmacology, 1994, Volume: 46, Issue:5 Topics: Acenaphthenes; Animals; Brain; Desipramine; Diuretics; Dopamine Agents; Haloperidol; Injections, Intraventricular; Kidney; Male; Molecular Structure; Natriuresis; Neurons; Oxidopamine; Potassium; Rats; Rats, Sprague-Dawley; Receptors, Dopamine	1994
Dopamine receptor mediated antidepressant action of B-HT 920 in mice. Indian journal of experimental biology, 1994, Volume: 32, Issue:3 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antidepressive Agents; Azepines; Desipramine; Drug Interactions; Escape Reaction; Female; Haloperidol; Male; Mice; Motor Activity; Receptors, Dopamine; Reserpine; Sulpiride; Swimming; Yohimbine	1994
On the characterization of dopamine-induced contractile response of rat anococcygeus muscle preparation. Indian journal of experimental biology, 1994, Volume: 32, Issue:3 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Azepines; Benzazepines; Desipramine; Dioxanes; Dopamine; Female; Haloperidol; Idazoxan; Male; Muscle Contraction; Prazosin; Rats; Receptors, Adrenergic; Receptors, Dopamine; Reserpine; Sulpiride; Yohimbine	1994
Effects of 7-hydroxy-N,N-di-n-propylaminotetralin on behaviour and blood pressure of spontaneously hypertensive rats. European journal of pharmacology, 1993, Oct-19, Volume: 243, Issue:2 Topics: Animals; Behavior, Animal; Blood Pressure; Body Temperature; Desipramine; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Heart Rate; Injections, Subcutaneous; Male; Motor Activity; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D3; Stereotyped Behavior; Tetrahydronaphthalenes; Yawning	1993
Effects of psychoactive drugs on temporal discrimination in rats. Behavioural pharmacology, 1997, Volume: 8, Issue:4 Topics: Animals; Atropine; Clomipramine; Desipramine; Diazepam; Discrimination Learning; Discrimination, Psychological; Haloperidol; Male; Nicotine; Psychotropic Drugs; Rats; Rats, Wistar; Scopolamine	1997
Long-term treatment with antidepressants increases glucocorticoid receptor binding and gene expression in cultured rat hippocampal neurones. Journal of neuroendocrinology, 1999, Volume: 11, Issue:11 Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Cells, Cultured; Desipramine; Dexamethasone; Gene Expression Regulation; Haloperidol; Hippocampus; Ketanserin; Mianserin; Neurons; Paroxetine; Phentolamine; Propranolol; Radioligand Assay; Rats; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; RNA, Messenger; Sulpiride; Transcription, Genetic; Tritium	1999
Dopaminergic and opioidergic mediations of tricyclic antidepressants in the learned helplessness paradigm. Pharmacology, biochemistry, and behavior, 1999, Volume: 64, Issue:3 Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents, Tricyclic; Desipramine; Dibenzocycloheptenes; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Drug Interactions; Escape Reaction; Haloperidol; Helplessness, Learned; Imipramine; Male; Motor Activity; Naloxone; Narcotic Antagonists; Opioid Peptides; Rats; Rats, Wistar	1999
Inhibitory effects of clozapine and other antipsychotic drugs on noradrenaline transporter in cultured bovine adrenal medullary cells. Psychopharmacology, 2000, Volume: 149, Issue:1 Topics: Adrenal Medulla; Animals; Antipsychotic Agents; Binding, Competitive; Carrier Proteins; Cattle; Cells, Cultured; Clozapine; Desipramine; Dose-Response Relationship, Drug; Female; Haloperidol; Kinetics; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Oocytes; Symporters; Tritium; Xenopus	2000
cAMP response element-mediated gene transcription is upregulated by chronic antidepressant treatment. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Jun-01, Volume: 20, Issue:11 Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antipsychotic Agents; beta-Galactosidase; Brain Chemistry; Cocaine; Coloring Agents; Cyclic AMP Response Element-Binding Protein; Desipramine; Dopamine Uptake Inhibitors; Fluoxetine; Haloperidol; Lac Operon; Mice; Mice, Transgenic; Monoamine Oxidase Inhibitors; Phosphorylation; Transcription, Genetic; Tranylcypromine; Up-Regulation	2000
Effects of the CRF(1) receptor antagonist, CP 154,526, in the separation-induced vocalization anxiolytic test in rat pups. Neuropharmacology, 2000, Jun-08, Volume: 39, Issue:8 Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Antipsychotic Agents; Anxiety; Behavior, Animal; Buspirone; Clozapine; Desipramine; Diazepam; Dose-Response Relationship, Drug; Female; Haloperidol; Injections, Intraperitoneal; Male; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Social Isolation; Stress, Psychological; Vocalization, Animal; Zimeldine	2000
Tail-swing behavior: a novel animal model for anxiety. Methods and findings in experimental and clinical pharmacology, 2003, Volume: 25, Issue:5 Topics: Animals; Anxiety; Behavior, Animal; Desipramine; Diazepam; Disease Models, Animal; Haloperidol; Immobilization; Male; Mice; Muscle Tonus; Muscle, Skeletal; Nitrazepam; Psychotropic Drugs; Tail	2003
[DRUGS ACTING ON THE NERVOUS SYSTEM. (2). WITH SPECIAL REFERENCE TO TRANQUILIZERS AND ANTIDEPRESSIVE AGENTS]. [Chiryo] [Therapy], 1963, Volume: 45 Topics: Amides; Amitriptyline; Antidepressive Agents; Benactyzine; Chemical Phenomena; Chemistry; Chlordiazepoxide; Desipramine; Diazepam; Haloperidol; Humans; Hydroxyzine; Hypnotics and Sedatives; Imipramine; Isocarboxazid; Meprobamate; Methylphenidate; Monoamine Oxidase Inhibitors; Nervous System; Nialamide; Pharmacology; Phenelzine; Piperidines; Tranquilizing Agents; Tranylcypromine; Tryptamines	1963
Enzymatic tissue digestion as an alternative sample preparation approach for quantitative analysis using liquid chromatography-tandem mass spectrometry. Analytical chemistry, 2004, Mar-15, Volume: 76, Issue:6 Topics: Animals; Antidepressive Agents; Brain; Chromatography, Liquid; Collagenases; Desipramine; Dogs; Dose-Response Relationship, Drug; Endopeptidase K; Esterases; Feasibility Studies; Female; Fluoxetine; Haloperidol; In Vitro Techniques; Mass Spectrometry; Rats; Rats, Sprague-Dawley; Time Factors	2004
Direct involvement of orexinergic systems in the activation of the mesolimbic dopamine pathway and related behaviors induced by morphine. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Jan-11, Volume: 26, Issue:2 Topics: Animals; Benzoxazoles; Conditioning, Operant; Desipramine; Dopamine; Female; Haloperidol; Injections, Intraventricular; Injections, Subcutaneous; Intracellular Signaling Peptides and Proteins; Limbic System; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Microdialysis; Microinjections; Morphine; Motor Activity; Naphthyridines; Neuropeptides; Nucleus Accumbens; Orexins; Oxidopamine; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Reward; RNA, Messenger; Tyrosine 3-Monooxygenase; Urea; Ventral Tegmental Area	2006
Effects of pregnanolone in rats discriminating cocaine. Pharmacology, biochemistry, and behavior, 2006, Volume: 85, Issue:2 Topics: Animals; Bupropion; Cocaine; Desipramine; Dextroamphetamine; Discrimination Learning; Dose-Response Relationship, Drug; Haloperidol; Male; Pregnanolone; Rats; Rats, Long-Evans; Receptors, GABA-A	2006
Efficacy of imipramine in psychotic versus nonpsychotic depression. Journal of clinical psychopharmacology, 2008, Volume: 28, Issue:2 Topics: Adult; Affective Disorders, Psychotic; Aged; Antidepressive Agents; Data Interpretation, Statistical; Depressive Disorder; Desipramine; Diagnostic and Statistical Manual of Mental Disorders; Drug Administration Schedule; Drug Therapy, Combination; Female; Haloperidol; Humans; Imipramine; Logistic Models; Lorazepam; Male; Middle Aged; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Time Factors; Treatment Outcome	2008
Evaluation of the repeated open-space swim model of depression in the mouse. Pharmacology, biochemistry, and behavior, 2008, Volume: 91, Issue:1 Topics: Adaptation, Psychological; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Cell Proliferation; Chronic Disease; Depression; Desipramine; Diazepam; Disease Models, Animal; Fluoxetine; Food Preferences; Haloperidol; Hindlimb Suspension; Hypnotics and Sedatives; Male; Mice; Motor Activity; Neurons; Swimming	2008
The triple reuptake inhibitor DOV216,303 exhibits limited antidepressant-like properties in the differential reinforcement of low-rate 72-second responding assay, likely due to dopamine reuptake inhibition. Journal of psychopharmacology (Oxford, England), 2011, Volume: 25, Issue:10 Topics: Animals; Antidepressive Agents; Aza Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bupropion; Desipramine; Diazepam; Dopamine Uptake Inhibitors; Fluvoxamine; Haloperidol; Imipramine; Male; Piperazines; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology	2011
HPC-1/syntaxin 1A gene knockout mice show abnormal behavior possibly related to a disruption in 5-HTergic systems. The European journal of neuroscience, 2010, Volume: 32, Issue:1 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Uptake Inhibitors; Amphetamines; Animals; Behavior, Animal; Desipramine; Dopamine Agonists; Dopamine Antagonists; Fluoxetine; Haloperidol; Hippocampus; Humans; Hypothalamus; Inhibition, Psychological; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenotype; Piperazines; Quinpirole; Receptor, Serotonin, 5-HT2A; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Social Behavior; Syntaxin 1	2010
Antidepressants elevate GDNF expression and release from C₆ glioma cells in a β-arrestin1-dependent, CREB interactive pathway. The international journal of neuropsychopharmacology, 2011, Volume: 14, Issue:10 Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Arrestins; beta-Arrestins; Brain Neoplasms; Cell Line, Tumor; Citalopram; Cyclic AMP Response Element-Binding Protein; Desipramine; Dose-Response Relationship, Drug; Glial Cell Line-Derived Neurotrophic Factor; Glioblastoma; Haloperidol; Imipramine; Neurotransmitter Uptake Inhibitors; Phosphorylation; Rats; RNA Interference; Selective Serotonin Reuptake Inhibitors; Signal Transduction; Transcription, Genetic; Transfection; Up-Regulation; Valproic Acid	2011
Clozapine reconstructed: Haloperidol's ability to reduce alcohol intake in the Syrian golden hamster can be enhanced through noradrenergic modulation by desipramine and idazoxan. Drug and alcohol dependence, 2015, Jul-01, Volume: 152 Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic Uptake Inhibitors; Adult; Alcohol Drinking; Animals; Clozapine; Desipramine; Dose-Response Relationship, Drug; Drug Synergism; Eating; Female; Haloperidol; Humans; Idazoxan; Male; Mesocricetus; Receptors, Dopamine D2	2015
Not All Antidepressants Are Created Equal: Differential Effects of Monoamine Uptake Inhibitors on Effort-Related Choice Behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2016, Volume: 41, Issue:3 Topics: Animals; Antidepressive Agents; Benzazepines; Bupropion; Choice Behavior; Desipramine; Dopamine Antagonists; Dose-Response Relationship, Drug; Fluoxetine; Haloperidol; Male; Motivation; Neurotransmitter Uptake Inhibitors; Piperazines; Rats, Sprague-Dawley; Tetrabenazine; Vesicular Monoamine Transport Proteins	2016