haloperidol and bromperidol

haloperidol has been researched along with bromperidol in 87 studies

Research

Studies (87)

TimeframeStudies, this research(%)All Research%
pre-199028 (32.18)18.7374
1990's23 (26.44)18.2507
2000's27 (31.03)29.6817
2010's8 (9.20)24.3611
2020's1 (1.15)2.80

Authors

AuthorsStudies
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Garneau-Tsodikova, S; Garzan, A; Green, KD; Holbrook, SYL; Hou, C; Krieger, K; Pang, AH; Parish, T; Posey, JE; Punetha, A; Thamban Chandrika, N; Tsodikov, OV; Willby, MJ1
Angst, J; Woggon, B1
Baeyens, W; De Moerloose, P1
Bures, E; Haage, H; Pöldinger, W1
Cookson, JC; McLaren, S; Silverstone, T1
Cassano, GB; Nisita, C; Nuccorini, A; Perretta, P; Santa, MD; Scasso, A; Zaccagnini, E1
Morimoto, T; Tadokoro, S; Uchihashi, Y1
Inaba, T; Someya, T; Takahashi, S; Tang, SW; Tyndale, RF1
Asano, M; Kumazawa, T; Seno, H; Suzuki, O1
Hariharan, M; Kindt, EK; Tandon, R; VanNoord, T1
Hikida, K; Inoue, Y; Kojima, N; Miyazaki, T; Ohkura, Y1
Applemans, A; Peuskens, J; Van Bellinghen, M1
Suárez Richards, M1
Heiss, WD; Laufer, P; Moerlein, SM; Pawlik, G; Stöcklin, G; Wienhard, K1
Ellerman, LA1
Benfield, P; Clark, BG; Jue, SG; Ward, A1
Bellomo, LE; Forconesi, N; Rosset, N; Tellarini, L1
Itoh, H1
Bonomo, V; Parisi, R; Rapisarda, V1
Moerlein, SM; Stöcklin, GL1
Digenis, GA; Kook, CS; Reiman, RE; Russ, GA; Tilbury, RS; Vincent, SH1
Ban, TA; Berney, SA; Brannen, JO; McEvoy, JP; Petrie, WM; Schaffer, JD; Wilson, WH1
Biggs, SR; Brodie, RR; Chasseaud, LF; Hawkins, DR; Midgley, I1
Dubinsky, B; Janssen, PA; McGuire, JL; McKenzie, BE; Niemegeers, CJ; Weintraub, HS1
Huang, KJ; Imai, S; Sudo, T; Takeshima, T; Tauchi, K1
Fujii, Y; Itoh, H; Kamisada, M; Nakajima, S; Takamiya, M; Tanoue, A; Tateyama, M1
Azibi, M; Bouche, R; Draguet-Brughmans, M1
Hetyei, N; Patrick, J; Tischio, J1
Denijs, EL1
Gubler, HR; Lum, SW; Martin, RP; McGonigle, EJ1
Ban, TA; Berney, S; Brannen, JO; McEvoy, JP; Wilson, WH1
Digenis, GA; Shambhu, MB; Vincent, SH1
Belpaire, FM; Bogaert, MG; De Moerloose, P; Van Den Eeckhout, E1
König, F; Straub, R; Wolfersdorf, M1
Kimura, T; Yoshida, H1
Ishii, A; Kumazawa, T; Sato, K; Seno, H; Suzuki, O1
Asai, M; Kanba, S; Koshikawa, H; Nibuya, M; Suzuki, E; Yagi, G1
Inoue, Y; Ishida, M; Kaneko, S; Kondo, T; Mihara, K; Otani, K; Suzuki, A; Yasui, N2
Inoue, Y; Ishida, M; Kaneko, S; Otani, K; Yasui, N1
Ikeda, K; Inoue, Y; Ishida, M; Kaneko, S; Kondo, T; Mihara, K; Otani, K; Shibata, M; Suzuki, A; Yasui, N2
Furukori, H; Inoue, Y; Ishida, M; Kaneko, S; Kondo, T; Mihara, K; Otani, K; Suzuki, A; Yasui, N1
Araki, T; Hongo, T; Kosaka, K; Miura, M; Ohkubo, T; Oshima, Y; Sugawara, K; Takeshita, M; Takeshita, Y1
Furukori, H; Hayashi, K; Inoue, Y; Kaneko, S; Kondo, T; Mihara, K; Otani, K; Suzuki, A; Tokinaga, N; Yasui, N1
Furukori, H1
Furukori, H; Inoue, Y; Kaneko, S; Kondo, T; Otani, K; Suzuki, A; Yasui, N1
Furukori, H; Inoue, Y; Ishida, M; Kaneko, S; Kondo, T; Mihara, K; Nagashima, U; Otani, K; Suzuki, A; Yasui, N1
Furukori, H; Inoue, Y; Kaneko, S; Kondo, T; Nagashima, U; Otani, K; Tokinaga, N; Yasui, N1
Kawano, J; Matunaka, S; Sakamoto, N; Sakamoto, Y1
Kobayashi, S; Kumai, T; Tanaka, M; Tateishi, T; Watanabe, M1
Kurita, H1
Inoue, Y; Koitabashi, T; Sato, S; Shioiri, O; Someya, T1
Hirokane, G; Muratake, T; Shibasaki, M; Shimoda, K; Someya, T; Takahashi, S1
Miura, M; Ohkubo, T; Sugawara, K; Takeshita, M1
Kaneko, S; Kondo, T; Mihara, K; Nagashima, U; Ono, S; Otani, K; Suzuki, A1
Kobayashi, S; Kumai, T; Moriya, H; Satoh, T; Tanaka, M; Tateishi, T; Watanabe, M; Yamaguchi, S1
Kaneko, S; Kondo, T; Mihara, K; Ono, S; Otani, K; Suzuki, A; Yasui, N1
Inoue, Y; Kaneko, S; Kondo, T; Mihara, K; Ono, S; Otani, K; Suzuki, A; Yasui-Furukori, N1
Furukori, H; Inoue, Y; Kaneko, S; Kondo, T; Mihara, K; Otani, K; Suzuki, A; Yasui-Furukori, N1
Furukori, H; Inoue, Y; Ishida, M; Kaneko, S; Kondo, T; Mihara, K; Otani, K; Suzuki, A; Yasui-Furukori, N1
Iwado, H; Morita, Y; Shinjo, H; Ueki, A1
Furukori, H; Inoue, M; Ishida, M; Kaneko, S; Kondo, T; Otani, K; Suzuki, A; Yasui-Furukori, N1
Ishida, M; Kaneko, S; Kondo, T; Mihara, K; Otani, K; Tanaka, O; Yasui-Furukori, N1
Kaneko, S; Kondo, T; Mihara, K; Otani, K; Suzuki, A; Yasui-Furukori, N1
Haasen, C; Krausz, M; Naber, D; Nika, E; Yagdiran, O1
Ohye, C; Shibazaki, T1
Furukori, H; Inoue, Y; Kaneko, S; Saito, M; Tateishi, T; Yasui-Furukori, N1
Chiba, M; Inoue, Y; Tateishi, T; Yasui-Furukori, N1
Furukori, H; Inoue, Y; Kaneko, S; Saito, M; Someya, T; Tateishi, T; Yasui-Furukori, N1
Abe, T; Kajii, E; Kato, S; Konno, T; Matsumoto, M; Tamba, K1
Hirokane, G; Shimoda, K1
Perquin, LN1
Kaneda, A; Kaneko, S; Nakagami, T; Saito, M; Tateishi, T; Yasui-Furukori, N1
Kim, HG; Kim, JW; Kim, YG; Lee, SY1
Fujii, Y; Higashi, Y; Nakamura, S1
Kondo, T; Mihara, K; Sakumoto, N; Suzuki, A; Yasui-Furukori, N1
Kashima, H; Suzuki, T; Uchida, H; Watanabe, K1
Goto, M; Kawabe, M; Kimura, S; Kon, K; Muneoka, K; Shirayama, Y1
Di Cosimo, D; Girardi, N; Kotzalidis, GD; Lazanio, S; Manfredi, G; Savoja, V; Talamo, A; Tatarelli, R; Vento, A1
Anderson, H; Av-Gay, Y; Chao, JD; Ng, C; Pfeifer, T; Ramón-García, S; Roberge, M; Thompson, CJ; Zheng, X1
Abe, R; Fujita, K; Futsukaichi, K; Matsumoto, K; Noguchi, T1
Gen, K; Inoue, Y; Suzuki, H1
Dold, M; Leucht, S; Li, C; Samara, MT; Tardy, M1
Dennis, EK; Garneau-Tsodikova, S; Garzan, A; Holbrook, SYL; Shrestha, SK1
Chowdhury, S; Kumar, S1

Reviews

5 review(s) available for haloperidol and bromperidol

ArticleYear
Bromperidol. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in psychoses.
    Drugs, 1988, Volume: 35, Issue:6

    Topics: Clinical Trials as Topic; Haloperidol; Humans; Psychotic Disorders

1988
[Clinical study of neuroleptic malignant syndrome in demented patients--examination of our case and reported cases].
    No to shinkei = Brain and nerve, 1994, Volume: 46, Issue:9

    Topics: Aged; Aged, 80 and over; Dementia; Dementia, Vascular; Female; Haloperidol; Humans; Male; Middle Aged; Neuroleptic Malignant Syndrome

1994
[Butyrophenone derivatives].
    Nihon rinsho. Japanese journal of clinical medicine, 1999, Volume: 57 Suppl

    Topics: Antipsychotic Agents; Drug Monitoring; Haloperidol; Humans

1999
[Butyrophenone derivatives].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 12

    Topics: Antipsychotic Agents; Biomarkers; Drug Interactions; Drug Monitoring; Haloperidol; Humans; Immunoenzyme Techniques; Treatment Refusal

2004
Haloperidol versus first-generation antipsychotics for the treatment of schizophrenia and other psychotic disorders.
    The Cochrane database of systematic reviews, 2015, Jan-16, Volume: 1

    Topics: Administration, Oral; Antipsychotic Agents; Haloperidol; Humans; Loxapine; Psychotic Disorders; Randomized Controlled Trials as Topic; Schizophrenia; Trifluoperazine

2015

Trials

22 trial(s) available for haloperidol and bromperidol

ArticleYear
Double-blind comparison of bromperidol and perphenazine.
    International pharmacopsychiatry, 1978, Volume: 13, Issue:3

    Topics: Adult; Aged; Behavior; Clinical Trials as Topic; Double-Blind Method; Female; Haloperidol; Humans; Male; Middle Aged; Perphenazine; Psychiatric Status Rating Scales; Schizophrenia; Time Factors

1978
Positive and negative symptoms, depression and social disability in chronic schizophrenia: a comparative trial of bromperidol and fluphenazine decanoates.
    International clinical psychopharmacology, 1992, Volume: 7, Issue:2

    Topics: Adult; Aged; Chronic Disease; Depression; Double-Blind Method; Female; Fluphenazine; Haloperidol; Humans; Male; Middle Aged; Schizophrenia; Schizophrenic Psychology; Social Behavior

1992
Diagnosis and clinical use of bromperidol in HIV-related psychoses in a sample of seropositive patients with brain damage.
    International clinical psychopharmacology, 1992, Volume: 7, Issue:2

    Topics: Adult; AIDS Dementia Complex; Female; Haloperidol; HIV Seropositivity; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Substance Abuse, Intravenous

1992
[Chronic treatment of schizophrenia with injectable bromperidol decanoate].
    Acta psiquiatrica y psicologica de America latina, 1985, Volume: 31, Issue:3

    Topics: Adult; Brief Psychiatric Rating Scale; Chronic Disease; Clinical Trials as Topic; Female; Haloperidol; Humans; Injections, Intramuscular; Male; Middle Aged; Schizophrenia

1985
[Treatment with bromperidol in schizophrenic patients].
    Acta psiquiatrica y psicologica de America latina, 1988, Volume: 34, Issue:4

    Topics: Brief Psychiatric Rating Scale; Clinical Trials as Topic; Female; Haloperidol; Humans; Male; Schizophrenia

1988
Bromperidol. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in psychoses.
    Drugs, 1988, Volume: 35, Issue:6

    Topics: Clinical Trials as Topic; Haloperidol; Humans; Psychotic Disorders

1988
[Clinical experience with bromperidol in chronic psychoses].
    Acta psiquiatrica y psicologica de America latina, 1988, Volume: 34, Issue:3

    Topics: Adolescent; Adult; Aged; Chronic Disease; Clinical Trials as Topic; Female; Haloperidol; Humans; Inpatients; Middle Aged; Paranoid Disorders; Psychotic Disorders; Schizophrenia

1988
A comparison of the clinical effects of bromperidol, a new butyrophenone derivative, and haloperidol on schizophrenia using a double-blind technique.
    Psychopharmacology bulletin, 1985, Volume: 21, Issue:1

    Topics: Clinical Trials as Topic; Double-Blind Method; Haloperidol; Humans; Schizophrenia

1985
A double-blind comparison of bromperidol and haloperidol in newly admitted schizophrenic patients.
    Pharmacopsychiatria, 1981, Volume: 14, Issue:4

    Topics: Antipsychotic Agents; Double-Blind Method; Drug Evaluation; Haloperidol; Humans; Psychiatric Status Rating Scales; Schizophrenia

1981
Clinical evaluation of bromperidol versus haloperidol in psychotic patients.
    International pharmacopsychiatry, 1980, Volume: 15, Issue:5

    Topics: Adult; Aged; Akathisia, Drug-Induced; Clinical Trials as Topic; Double-Blind Method; Drug Tolerance; Female; Haloperidol; Humans; Male; Middle Aged; Parkinson Disease, Secondary; Psychotic Disorders; Salivation; Tremor

1980
Bromperidol maintenance in schizophrenia.
    Pharmacopsychiatria, 1982, Volume: 15, Issue:3

    Topics: Double-Blind Method; Haloperidol; Humans; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology

1982
No interaction between desipramine and bromperidol.
    Progress in neuro-psychopharmacology & biological psychiatry, 1996, Volume: 20, Issue:7

    Topics: Adult; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2D6; Desipramine; Drug Interactions; Female; Haloperidol; Humans; Male; Oxidation-Reduction; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology

1996
No effect of the anticholinergic drugs trihexyphenidyl and biperiden on the plasma concentrations of bromperidol and its reduced metabolite.
    Therapeutic drug monitoring, 1997, Volume: 19, Issue:2

    Topics: Adult; Biperiden; Drug Interactions; Female; Haloperidol; Humans; Male; Middle Aged; Schizophrenia; Trihexyphenidyl

1997
Increased plasma concentrations of bromperidol and its reduced metabolite with levomepromazine, but not with thioridazine.
    Therapeutic drug monitoring, 1997, Volume: 19, Issue:3

    Topics: Adult; Anti-Dyskinesia Agents; Antipsychotic Agents; Cytochrome P-450 CYP2D6; Haloperidol; Humans; Methotrimeprazine; Middle Aged; Schizophrenia; Thioridazine

1997
Effects of various factors including the CYP2D6 genotype and coadministration of flunitrazepam on the steady-state plasma concentrations of bromperidol and its reduced metabolite.
    Psychopharmacology, 1998, Volume: 135, Issue:4

    Topics: Adolescent; Adult; Aged; Aging; Anti-Anxiety Agents; Antipsychotic Agents; Biotransformation; Cytochrome P-450 CYP2D6; Female; Flunitrazepam; Genotype; Half-Life; Haloperidol; Humans; Male; Middle Aged; Oxidation-Reduction; Schizophrenia; Sex Characteristics; Smoking

1998
No pharmacokinetic but pharmacodynamic interactions between cisapride and bromperidol or haloperidol.
    Therapeutic drug monitoring, 1999, Volume: 21, Issue:3

    Topics: Antipsychotic Agents; Cisapride; Drug Interactions; Female; Gastrointestinal Agents; Haloperidol; Humans; Male; Middle Aged

1999
No relationship between Taq1 a polymorphism of dopamine D(2) receptor gene and extrapyramidal adverse effects of selective dopamine D(2) antagonists, bromperidol, and nemonapride in schizophrenia: a preliminary study.
    American journal of medical genetics, 2000, Jun-12, Volume: 96, Issue:3

    Topics: Acute Disease; Alleles; Antipsychotic Agents; Benzamides; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Extrapyramidal Tracts; Female; Haloperidol; Humans; Male; Pilot Projects; Polymorphism, Restriction Fragment Length; Receptors, Dopamine D2; Reproducibility of Results; Schizophrenia

2000
No relationship between--141C Ins/Del polymorphism in the promoter region of dopamine D2 receptor and extrapyramidal adverse effects of selective dopamine D2 antagonists in schizophrenic patients: a preliminary study.
    Psychiatry research, 2001, Feb-14, Volume: 101, Issue:1

    Topics: Adult; Benzamides; Dopamine Antagonists; Female; Haloperidol; Humans; Male; Polymorphism, Genetic; Receptors, Dopamine D2; Schizophrenia

2001
Association between TaqI A dopamine D2 receptor polymorphism and therapeutic response to bromperidol: a preliminary report.
    European archives of psychiatry and clinical neuroscience, 2001, Volume: 251, Issue:2

    Topics: Adult; Antipsychotic Agents; Dopamine Antagonists; Female; Haloperidol; Humans; Male; Polymorphism, Genetic; Psychiatric Status Rating Scales; Receptors, Dopamine D2; Schizophrenia; Taq Polymerase

2001
Therapeutic effects of bromperidol on the five dimensions of schizophrenic symptoms.
    Progress in neuro-psychopharmacology & biological psychiatry, 2002, Volume: 26, Issue:1

    Topics: Adult; Antipsychotic Agents; Female; Haloperidol; Humans; Male; Middle Aged; Patient Compliance; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology

2002
Establishment of new cloned enzyme donor immunoassays (CEDIA) for haloperidol and bromperidol.
    Therapeutic drug monitoring, 2004, Volume: 26, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Autoanalysis; Cross Reactions; Drug Monitoring; Female; Haloperidol; Humans; Immunoenzyme Techniques; Male; Middle Aged; Reproducibility of Results; Schizophrenia

2004
Pharmacokinetic parameters of bromperidol in Korean subjects.
    Human psychopharmacology, 2006, Volume: 21, Issue:6

    Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Dystonia; Female; Genotype; Haloperidol; Humans; Korea; Male; Reference Values

2006

Other Studies

61 other study(ies) available for haloperidol and bromperidol

ArticleYear
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from
    RSC medicinal chemistry, 2021, Nov-17, Volume: 12, Issue:11

    Topics:

2021
Fluorometric determination of some butyrophenones after permanganate treatment.
    Die Pharmazie, 1977, Volume: 32, Issue:12

    Topics: Azaperone; Butyrophenones; Chromatography, Thin Layer; Fluorometry; Haloperidol; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methods; Potassium Permanganate; Spectrophotometry, Atomic; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet

1977
Clinical study with bromperidol, a new butyrophenone derivative.
    International pharmacopsychiatry, 1977, Volume: 12, Issue:1

    Topics: Adult; Bromine; Female; Haloperidol; Humans; Male; Middle Aged; Schizophrenia

1977
[Effects of mosapramine (Y-516), a new dopamine D2 antagonist, on reverse tolerance after repeated administration of methamphetamine by means of the ambulation-increasing effect in mice].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1992, Volume: 99, Issue:3

    Topics: Animals; Benzazepines; Chlorpromazine; Dibenzazepines; Dopamine Antagonists; Drug Tolerance; Drugs, Chinese Herbal; Haloperidol; Locomotion; Male; Methamphetamine; Mice; Mice, Inbred Strains; Tranquilizing Agents

1992
Conversion of bromperidol to reduced bromperidol in human liver.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1991, Volume: 5, Issue:3

    Topics: Alcohol Oxidoreductases; Chromatography, High Pressure Liquid; Haloperidol; Humans; In Vitro Techniques; Kinetics; Liver; Oxidation-Reduction

1991
Rapid isolation with Sep-Pak C18 cartridges and wide-bore capillary gas chromatography of some butyrophenones.
    Zeitschrift fur Rechtsmedizin. Journal of legal medicine, 1989, Volume: 102, Issue:2-3

    Topics: Antipsychotic Agents; Butyrophenones; Chromatography, Gas; Haloperidol; Humans; Spiperone

1989
An improved sensitive assay for simultaneous determination of plasma haloperidol and reduced haloperidol levels by liquid chromatography using a coulometric detector.
    Therapeutic drug monitoring, 1989, Volume: 11, Issue:6

    Topics: Chromatography, High Pressure Liquid; Chromatography, Liquid; Electrochemistry; Haloperidol; Humans; Hydrogen-Ion Concentration; Oxidation-Reduction; Psychotropic Drugs; Spectrophotometry, Ultraviolet

1989
Determination of bromperidol in serum by automated column-switching high-performance liquid chromatography.
    Journal of chromatography, 1989, Oct-27, Volume: 495

    Topics: Adult; Animals; Chromatography, High Pressure Liquid; Dogs; Haloperidol; Humans; Male; Spectrophotometry, Ultraviolet

1989
Hepatotoxicity following treatment with bromperidol.
    Journal of clinical psychopharmacology, 1989, Volume: 9, Issue:5

    Topics: Adult; Bipolar Disorder; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Female; Haloperidol; Humans; Liver Function Tests

1989
Evaluation of 75Br-labelled butyrophenone neuroleptics for imaging cerebral dopaminergic receptor areas using positron emission tomography.
    European journal of nuclear medicine, 1986, Volume: 12, Issue:4

    Topics: Animals; Antipsychotic Agents; Benperidol; Brain; Bromine; Cerebellum; Female; Haloperidol; Radioisotopes; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Tomography, Emission-Computed

1986
Long-acting therapy of schizophrenia.
    Advances in biochemical psychopharmacology, 1985, Volume: 40

    Topics: Adolescent; Adult; Antiparkinson Agents; Benzodiazepines; Biofeedback, Psychology; Bromocriptine; Dyskinesia, Drug-Induced; Female; Fluphenazine; Haloperidol; Humans; Male; Middle Aged; Pimozide; Schizophrenia; Trimeprazine

1985
Synthesis of high specific activity [75Br]- and [77Br]bromperidol and tissue distribution studies in the rat.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:9

    Topics: Animals; Brain; Bromine; Chemical Phenomena; Chemistry; Female; Haloperidol; Isotope Labeling; Kidney; Kinetics; Liver; Lung; Radioisotopes; Rats; Rats, Inbred Strains; Tissue Distribution; Trimethyltin Compounds

1985
Tissue distribution studies of [18F]haloperidol, [18F]-beta-(4-fluorobenzoyl)propionic acid, and [82Br]bromperidol by external scintigraphy.
    Journal of pharmaceutical sciences, 1981, Volume: 70, Issue:9

    Topics: Animals; Bromine Radioisotopes; Fluorine Radioisotopes; Haloperidol; Macaca mulatta; Male; Propionates; Rats; Rats, Sprague-Dawley; Tissue Distribution

1981
A novel conjugate as a major metabolite of bromperidol in man.
    The Journal of pharmacy and pharmacology, 1982, Volume: 34, Issue:5

    Topics: Biotransformation; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Haloperidol; Humans; Hydrolysis; Mass Spectrometry

1982
Bromperidol, a new butyrophenone neuroleptic: a review.
    Psychopharmacology, 1982, Volume: 78, Issue:1

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Binding, Competitive; Biotransformation; Brain; Chlorpromazine; Dogs; Female; Half-Life; Haloperidol; Male; Mice; Naloxone; Rats; Receptors, Dopamine; Receptors, Opioid

1982
[Teratogenicity study on bromperidol in rats].
    The Journal of toxicological sciences, 1984, Volume: 9 Suppl 1

    Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Antipsychotic Agents; Behavior, Animal; Body Weight; Embryonic and Fetal Development; Female; Fetus; Haloperidol; Organ Size; Pregnancy; Rats; Rats, Inbred Strains; Reproduction

1984
Clinical efficacy, extrapyramidal symptoms and serum levels: influence of administration schedules and concomitant drugs on serum bromperidol concentrations.
    Folia psychiatrica et neurologica japonica, 1984, Volume: 38, Issue:2

    Topics: Adult; Biperiden; Brief Psychiatric Rating Scale; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Kinetics; Male; Methotrimeprazine; Middle Aged; Schizophrenia

1984
Polymorphism of butyrophenones related to haloperidol.
    Journal of pharmaceutical sciences, 1984, Volume: 73, Issue:4

    Topics: Butyrophenones; Calorimetry, Differential Scanning; Chemical Phenomena; Chemistry, Physical; Crystallization; Haloperidol; Spectrophotometry, Infrared; Thermodynamics; X-Ray Diffraction

1984
Bromperidol radioimmunoassay: human plasma levels.
    Journal of pharmaceutical sciences, 1984, Volume: 73, Issue:4

    Topics: Antibody Specificity; Biological Availability; Biotransformation; Cross Reactions; Haloperidol; Humans; Kinetics; Quality Control; Radioimmunoassay; Schizophrenia

1984
GLC determination of bromperidol in tablets.
    Journal of pharmaceutical sciences, 1982, Volume: 71, Issue:1

    Topics: Chromatography, Gas; Drug Stability; Haloperidol; Spectrophotometry, Ultraviolet; Tablets

1982
Synthesis of [82Br]bromperidol and preliminary tissue distribution studies in the rat.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:1

    Topics: Animals; Bromine; Haloperidol; Isotope Labeling; Kinetics; Male; Radioisotopes; Rats; Tissue Distribution

1980
Radioimmunoassay of bromperidol and haloperidol in human and canine plasma.
    European journal of drug metabolism and pharmacokinetics, 1980, Volume: 5, Issue:1

    Topics: Animals; Dogs; Haloperidol; Humans; Rabbits; Radioimmunoassay; Time Factors

1980
Pharmacotherapy of delusional depression: experience with combinations of antidepressants with the neuroleptics zotepine and haloperidol.
    Neuropsychobiology, 1994, Volume: 29, Issue:4

    Topics: Adult; Amitriptyline; Antipsychotic Agents; Delusions; Depressive Disorder; Dibenzothiepins; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Haloperidol; Humans; Male; Maprotiline; Middle Aged; Psychiatric Status Rating Scales

1994
Determination of some butyrophenones in body fluids by gas chromatography with surface ionization detection.
    Nihon hoigaku zasshi = The Japanese journal of legal medicine, 1993, Volume: 47, Issue:5

    Topics: Butyrophenones; Chromatography, Gas; Haloperidol; Humans; Schizophrenia; Sensitivity and Specificity; Surface Properties

1993
Negative symptoms in nondeficit syndrome respond to neuroleptic treatment with changes in plasma homovanillic acid concentrations.
    Journal of psychiatry & neuroscience : JPN, 1996, Volume: 21, Issue:3

    Topics: Adult; Aged; Antipsychotic Agents; Depression; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Haloperidol; Homovanillic Acid; Humans; Middle Aged; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Treatment Outcome

1996
Possible interaction between cisapride and bromperidol.
    Progress in neuro-psychopharmacology & biological psychiatry, 1997, Volume: 21, Issue:1

    Topics: Adult; Cisapride; Drug Interactions; Haloperidol; Humans; Male; Piperidines; Schizophrenia; Sympathomimetics

1997
Interaction between carbamazepine and bromperidol.
    European journal of clinical pharmacology, 1997, Volume: 52, Issue:3

    Topics: Adult; Analgesics, Non-Narcotic; Antipsychotic Agents; Carbamazepine; Chromatography, High Pressure Liquid; Drug Interactions; Female; Haloperidol; Humans; Male; Middle Aged; Schizophrenia

1997
Synthesis and cataleptic effects of optically active dihydrohaloperidols and dihydrobromoperidols.
    Chirality, 1997, Volume: 9, Issue:5-6

    Topics: Animals; Catalepsy; Haloperidol; Male; Mice; Mice, Inbred Strains; Molecular Structure; Motor Activity; Stereoisomerism; Structure-Activity Relationship

1997
Prolactin response to bromperidol treatment in schizophrenic patients.
    Pharmacology & toxicology, 1998, Volume: 82, Issue:3

    Topics: Adult; Antipsychotic Agents; Female; Haloperidol; Humans; Male; Middle Aged; Prolactin; Schizophrenia

1998
[Involvement of cytochromeP4503A4 in the metabolism of haloperidol and bromperidol].
    Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 1998, Volume: 18, Issue:1

    Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Haloperidol; Humans; Inactivation, Metabolic; Itraconazole; Male; Middle Aged; Mixed Function Oxygenases; Schizophrenia

1998
Correlation between steady-state plasma concentrations (Css) of bromperidol and haloperidol.
    Progress in neuro-psychopharmacology & biological psychiatry, 1998, Volume: 22, Issue:3

    Topics: Adult; Aged; Antipsychotic Agents; Female; Haloperidol; Humans; Male; Middle Aged; Schizophrenia

1998
Effects of itraconazole on the steady-state plasma concentrations of bromperidol and reduced bromperidol in schizophrenic patients.
    Psychopharmacology, 1999, Volume: 145, Issue:2

    Topics: Adult; Aged; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Enzyme Inhibitors; Female; Haloperidol; Humans; Itraconazole; Middle Aged; Mixed Function Oxygenases; Schizophrenia

1999
Role of CYP3A in bromperidol metabolism in rat in vitro and in vivo.
    Xenobiotica; the fate of foreign compounds in biological systems, 1999, Volume: 29, Issue:8

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Inhibitors; Erythromycin; Half-Life; Haloperidol; Immune Sera; Male; Microsomes, Liver; Oxidoreductases, N-Demethylating; Propionates; Quinine; Rats; Rats, Sprague-Dawley; Steroid Hydroxylases; Theophylline; Troleandomycin

1999
Brief report: delusional disorder in a male adolescent with high-functioning PDDNOS.
    Journal of autism and developmental disorders, 1999, Volume: 29, Issue:5

    Topics: Adolescent; Adult; Antipsychotic Agents; Autistic Disorder; Child Development Disorders, Pervasive; Comorbidity; Delusions; Diagnosis, Differential; Follow-Up Studies; Haloperidol; Humans; Intelligence; Male; Psychiatric Status Rating Scales

1999
Involvement of CYP3A4 in the metabolism of bromperidol in vitro.
    Pharmacology & toxicology, 2000, Volume: 86, Issue:3

    Topics: Aryl Hydrocarbon Hydroxylases; Cell Fractionation; Cell Line; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Haloperidol; Humans; Microsomes; Mixed Function Oxygenases

2000
Interindividual variation in bromperidol metabolism and relationship to therapeutic effects.
    Journal of clinical psychopharmacology, 2000, Volume: 20, Issue:2

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Biotransformation; Dose-Response Relationship, Drug; Female; Haloperidol; Humans; Individuality; Male; Metabolic Clearance Rate; Middle Aged; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology

2000
Asymmetric redox reactions in human liver stereoselective oxidation of optically active dihydrohaloperidols, dihydrobromoperidols and stereospecific reduction of haloperidol and bromoperidol.
    Enantiomer, 2000, Volume: 5, Issue:2

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Cytosol; Haloperidol; Humans; Microsomes, Liver; Mixed Function Oxygenases; Oxidation-Reduction; Stereoisomerism

2000
CYP3A is responsible for N-dealkylation of haloperidol and bromperidol and oxidation of their reduced forms by human liver microsomes.
    Life sciences, 2000, Nov-03, Volume: 67, Issue:24

    Topics: Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Haloperidol; Humans; In Vitro Techniques; Microsomes, Liver; Mixed Function Oxygenases; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Propionates; Troleandomycin

2000
Relationship between Taq1 A dopamine D2 receptor (DRD2) polymorphism and prolactin response to bromperidol.
    American journal of medical genetics, 2001, Apr-08, Volume: 105, Issue:3

    Topics: Adult; Alleles; Deoxyribonucleases, Type II Site-Specific; Dopamine Antagonists; Female; Genotype; Haloperidol; Humans; Hyperprolactinemia; Japan; Male; Middle Aged; Polymorphism, Genetic; Prolactin; Receptors, Dopamine D2; Schizophrenia; Sex Factors

2001
The -141C Ins/Del polymorphism in the dopamine D2 receptor gene promoter region is associated with anxiolytic and antidepressive effects during treatment with dopamine antagonists in schizophrenic patients.
    Pharmacogenetics, 2001, Volume: 11, Issue:6

    Topics: Adult; Antipsychotic Agents; Anxiety; Benzamides; Depression; Dopamine Antagonists; Female; Haloperidol; Humans; Male; Middle Aged; Polymorphism, Genetic; Receptors, Dopamine D2; Schizophrenia

2001
[Malignant syndrome caused by a combination of bromperidol and donepezil hydrochloride in a patient with probable dementia with Lewy bodies].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 2001, Volume: 38, Issue:6

    Topics: Aged; Donepezil; Drug Therapy, Combination; Hallucinations; Haloperidol; Humans; Indans; Lewy Body Disease; Male; Neuroleptic Malignant Syndrome; Nootropic Agents; Piperidines

2001
The characteristics of side-effects of bromperidol in schizophrenic patients.
    Psychiatry and clinical neurosciences, 2002, Volume: 56, Issue:1

    Topics: Adult; Antipsychotic Agents; Dystonia; Female; Haloperidol; Humans; Hypokinesia; Male; Schizophrenia; Schizophrenic Psychology; Tremor

2002
Comparison of prolactin concentrations between haloperidol and bromperidol treatments in schizophrenic patients.
    Progress in neuro-psychopharmacology & biological psychiatry, 2002, Volume: 26, Issue:3

    Topics: Adult; Female; Haloperidol; Humans; Male; Middle Aged; Prolactin; Schizophrenia; Statistics, Nonparametric

2002
Switching to amisulpride due to hepatic complications.
    European psychiatry : the journal of the Association of European Psychiatrists, 2002, Volume: 17, Issue:3

    Topics: Adult; Amisulpride; Antipsychotic Agents; Chemical and Drug Induced Liver Injury; Flupenthixol; Haloperidol; Humans; Male; Perazine; Schizophrenia; Sulpiride

2002
Lesioning the thalamus for dyskinesia.
    Stereotactic and functional neurosurgery, 2001, Volume: 77, Issue:1-4

    Topics: Antiparkinson Agents; Antipsychotic Agents; Dyskinesia, Drug-Induced; Dyskinesias; Electrocoagulation; Haloperidol; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Parkinsonian Disorders; Reoperation; Retrospective Studies; Schizophrenia; Stereotaxic Techniques; Sulpiride; Torticollis; Treatment Outcome; Tremor; Ventral Thalamic Nuclei

2001
Poor reliability of therapeutic drug monitoring data for haloperidol and bromperidol using enzyme immunoassay.
    Therapeutic drug monitoring, 2003, Volume: 25, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Chromatography, High Pressure Liquid; Drug Monitoring; Female; Haloperidol; Humans; Immunoenzyme Techniques; Male; Middle Aged; Reagent Kits, Diagnostic

2003
Simultaneous determination of haloperidol and bromperidol and their reduced metabolites by liquid-liquid extraction and automated column-switching high-performance liquid chromatography.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2004, Jun-05, Volume: 805, Issue:1

    Topics: Antipsychotic Agents; Automation; Chromatography, High Pressure Liquid; Haloperidol; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet

2004
Two cases of deep vein thrombosis associated with antipsychotic drug use.
    Psychiatry and clinical neurosciences, 2004, Volume: 58, Issue:4

    Topics: Aged; Antipsychotic Agents; Chlorpromazine; Depressive Disorder, Major; Dose-Response Relationship, Drug; Drug Overdose; Drug Therapy, Combination; Female; Flunitrazepam; Haloperidol; Humans; Middle Aged; Pulmonary Embolism; Risk; Schizophrenia; Venous Thrombosis

2004
Treatment with the new antipsychotic sertindole for late-occurring undesirable movement effects.
    International clinical psychopharmacology, 2005, Volume: 20, Issue:6

    Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Clopenthixol; Female; Haloperidol; Humans; Imidazoles; Indoles; Male; Middle Aged; Schizophrenia; Time Factors

2005
Association between multidrug resistance 1 (MDR1) gene polymorphisms and therapeutic response to bromperidol in schizophrenic patients: a preliminary study.
    Progress in neuro-psychopharmacology & biological psychiatry, 2006, Volume: 30, Issue:2

    Topics: Adult; Antipsychotic Agents; Female; Genes, MDR; Genotype; Haloperidol; Humans; Male; Middle Aged; Pharmacogenetics; Polymorphism, Genetic; Psychiatric Status Rating Scales; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Schizophrenia

2006
Sensitive determination of 4-(4-bromophenyl)-4-hydroxypiperidine, a metabolite of bromperidol, in rat plasma by HPLC with fluorescence detection after pre-column derivatization using 4-fluoro-7-nitro-2,1,3-benzoxadiazole.
    Biological & pharmaceutical bulletin, 2006, Volume: 29, Issue:12

    Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Area Under Curve; Chromatography, High Pressure Liquid; Haloperidol; Male; Piperidines; Rats; Rats, Wistar; Sensitivity and Specificity; Spectrometry, Fluorescence

2006
Dopamine D2 receptor gene polymorphisms predict well the response to dopamine antagonists at therapeutic dosages in patients with schizophrenia.
    Psychiatry and clinical neurosciences, 2007, Volume: 61, Issue:2

    Topics: Adult; Antipsychotic Agents; Biomarkers; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Genotype; Haloperidol; Humans; Male; Polymorphism, Genetic; Predictive Value of Tests; Psychiatric Status Rating Scales; Receptors, Dopamine D2; Reverse Transcriptase Polymerase Chain Reaction; Schizophrenia; Schizophrenic Psychology

2007
Minimizing antipsychotic medication obviated the need for enema against severe constipation leading to paralytic ileus: a case report.
    Journal of clinical pharmacy and therapeutics, 2007, Volume: 32, Issue:5

    Topics: Aged; Antipsychotic Agents; Constipation; Dementia; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enema; Haloperidol; Humans; Intestinal Pseudo-Obstruction; Male; Schizophrenia

2007
Improvement of mutism in a catatonic schizophrenia case by add-on treatment with amantadine.
    Pharmacopsychiatry, 2010, Volume: 43, Issue:4

    Topics: Amantadine; Antiparkinson Agents; Drug Therapy, Combination; Female; Haloperidol; Humans; Middle Aged; Mutism; Schizophrenia, Catatonic

2010
Folie à deux: double case-report of shared delusions with a fatal outcome.
    La Clinica terapeutica, 2011, Volume: 162, Issue:1

    Topics: Adult; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Clozapine; Combined Modality Therapy; Epilepsy; Fatal Outcome; Female; Haloperidol; Humans; Nordazepam; Olanzapine; Patient Compliance; Psychotherapy; Psychotic Disorders; Schizophrenia, Paranoid; Shared Paranoid Disorder; Sibling Relations; Suicide; Valproic Acid

2011
Synergistic drug combinations for tuberculosis therapy identified by a novel high-throughput screen.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:8

    Topics: Antitubercular Agents; Drug Synergism; Drug Therapy, Combination; Haloperidol; High-Throughput Screening Assays; Humans; Macrophages; Mycobacterium smegmatis; Mycobacterium tuberculosis; Spectinomycin; Tuberculosis

2011
[Severe hypotension and ventricular fibrillation during combined general and epidural anesthesia in a patient on major tranquilizers].
    Masui. The Japanese journal of anesthesiology, 2012, Volume: 61, Issue:10

    Topics: Anesthesia, Epidural; Anesthesia, General; Antipsychotic Agents; Haloperidol; Humans; Hypotension; Intraoperative Complications; Male; Middle Aged; Nephrectomy; Phenothiazines; Schizophrenia; Severity of Illness Index; Time Factors; Ventricular Fibrillation

2012
Comparison of the anti-dopamine D₂ and anti-serotonin 5-HT(2A) activities of chlorpromazine, bromperidol, haloperidol and second-generation antipsychotics parent compounds and metabolites thereof.
    Journal of psychopharmacology (Oxford, England), 2013, Volume: 27, Issue:4

    Topics: Adult; Algorithms; Antipsychotic Agents; Biotransformation; Brain; Chlorpromazine; Diagnostic and Statistical Manual of Mental Disorders; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Female; Haloperidol; Humans; Male; Middle Aged; Neurons; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Schizophrenia; Serotonin 5-HT2 Receptor Antagonists; Young Adult

2013
Repurposing antipsychotic drugs into antifungal agents: Synergistic combinations of azoles and bromperidol derivatives in the treatment of various fungal infections.
    European journal of medicinal chemistry, 2017, Oct-20, Volume: 139

    Topics: Animals; Antifungal Agents; Antipsychotic Agents; Azoles; Biofilms; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Fungi; Haloperidol; HEK293 Cells; Humans; Mice; Microbial Sensitivity Tests; Molecular Structure; Mycoses; Structure-Activity Relationship

2017
In silico repurposing of antipsychotic drugs for Alzheimer's disease.
    BMC neuroscience, 2017, 10-27, Volume: 18, Issue:1

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid Precursor Protein Secretases; Antipsychotic Agents; Aspartic Acid Endopeptidases; Butyrophenones; Butyrylcholinesterase; Drug Repositioning; Glucosides; Haloperidol; Humans; Molecular Docking Simulation; Molecular Structure; Monoamine Oxidase; Norisoprenoids; Pimozide; Psychotropic Drugs; Receptors, N-Methyl-D-Aspartate

2017