haloperidol and alprazolam

haloperidol has been researched along with alprazolam in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19903 (11.11)18.7374
1990's5 (18.52)18.2507
2000's12 (44.44)29.6817
2010's6 (22.22)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Li, Y; Li, YH; Wang, YH; Yang, L; Yang, SL1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Abraham, MH; Acree, WE; Ibrahim, A1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Artursson, P; Mateus, A; Matsson, P1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jadhav, A; Kerns, E; Nguyen, K; Shah, P; Sun, H; Xu, X; Yan, Z; Yu, KR1
Kabir, M; Kerns, E; Nguyen, K; Shah, P; Sun, H; Wang, Y; Xu, X; Yu, KR1
Kabir, M; Kerns, E; Neyra, J; Nguyen, K; Nguyễn, ÐT; Shah, P; Siramshetty, VB; Southall, N; Williams, J; Xu, X; Yu, KR1
Barbee, JG; Freed, CR; Mancuso, DM; Todorov, AA1
Angrist, B; Cooper, T; Douyon, R; Peselow, E; Rotrosen, J1
Cagiano, R; Cuomo, V; De Salvia, MA; Maselli, MA; Racagni, G; Renna, G1
Kahn, JP; Klein, DF; Puertollano, M; Schane, MD1
Jordan, J1
Monfort, JC1
Benfield, WR; Christensen, DB1
Hijzen, TH; Joordens, RJ; Olivier, B1
Greenberg, MI; Hendrickson, RG; Morocco, AP1
Krzek, J; Maślanka, A; Szlósarczyk, M; Wach, K; Żmudzki, P1

Reviews

1 review(s) available for haloperidol and alprazolam

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for haloperidol and alprazolam

ArticleYear
Alprazolam as a neuroleptic adjunct in the emergency treatment of schizophrenia.
    The American journal of psychiatry, 1992, Volume: 149, Issue:4

    Topics: Adult; Alprazolam; Antipsychotic Agents; Double-Blind Method; Drug Therapy, Combination; Emergencies; Emergency Services, Psychiatric; Female; Haloperidol; Humans; Male; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology

1992
Alprazolam as an alternative to low-dose haloperidol in older, cognitively impaired nursing facility patients.
    Journal of the American Geriatrics Society, 1998, Volume: 46, Issue:5

    Topics: Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Antipsychotic Agents; Behavioral Symptoms; Cognition Disorders; Cross-Over Studies; Double-Blind Method; Female; Haloperidol; Humans; Male; Nursing Homes

1998

Other Studies

24 other study(ies) available for haloperidol and alprazolam

ArticleYear
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
    Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11

    Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism.
    Bioorganic & medicinal chemistry letters, 2005, Sep-15, Volume: 15, Issue:18

    Topics: Computational Biology; Cyclohexanols; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Molecular Structure; Principal Component Analysis; Pyrrolizidine Alkaloids; Quantitative Structure-Activity Relationship; Reproducibility of Results; Substrate Specificity; Venlafaxine Hydrochloride

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:3

    Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
Highly predictive and interpretable models for PAMPA permeability.
    Bioorganic & medicinal chemistry, 2017, 02-01, Volume: 25, Issue:3

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Humans; Models, Biological; Organic Chemicals; Regression Analysis; Support Vector Machine

2017
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
    Bioorganic & medicinal chemistry, 2019, 07-15, Volume: 27, Issue:14

    Topics: Drug Discovery; Organic Chemicals; Pharmaceutical Preparations; Solubility

2019
Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models.
    Scientific reports, 2020, 11-26, Volume: 10, Issue:1

    Topics: Animals; Computer Simulation; Databases, Factual; Drug Discovery; High-Throughput Screening Assays; Liver; Machine Learning; Male; Microsomes, Liver; National Center for Advancing Translational Sciences (U.S.); Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Retrospective Studies; United States

2020
Neuroleptic augmentation with alprazolam: clinical effects and pharmacokinetic correlates.
    The American journal of psychiatry, 1989, Volume: 146, Issue:2

    Topics: Adult; Alprazolam; Antipsychotic Agents; Basal Ganglia Diseases; Drug Synergism; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Fluphenazine; Haloperidol; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology

1989
Ultrasonic vocalization in response to unavoidable aversive stimuli in rats: effects of benzodiazepines.
    Life sciences, 1988, Volume: 43, Issue:6

    Topics: Alprazolam; Animals; Benzodiazepines; Desipramine; Diazepam; Electroshock; Flumazenil; Haloperidol; Male; Rats; Rats, Inbred Strains; Ultrasonics; Vocalization, Animal

1988
Schizophrenia, panic anxiety, and alprazolam.
    The American journal of psychiatry, 1987, Volume: 144, Issue:4

    Topics: Adult; Alprazolam; Anxiety Disorders; Drug Therapy, Combination; Fear; Haloperidol; Humans; Male; Panic; Schizophrenia

1987
Use of a revised version of the psychotropic medication efficacy graph.
    Mental retardation, 1994, Volume: 32, Issue:2

    Topics: Adult; Alprazolam; Haloperidol; Humans; Intellectual Disability; Male; Neurocognitive Disorders; Personality Disorders; Treatment Outcome

1994
Alprazolam in the emergency treatment of schizophrenia.
    The American journal of psychiatry, 1993, Volume: 150, Issue:2

    Topics: Alprazolam; Drug Therapy, Combination; Emergencies; Haloperidol; Humans; Schizophrenia

1993
The anxiolytic effect on the fear-potentiated startle is not due to a non-specific disruption.
    Life sciences, 1998, Volume: 63, Issue:25

    Topics: Alprazolam; Animals; Anti-Anxiety Agents; Antipsychotic Agents; Central Nervous System Depressants; Chlordiazepoxide; Ethanol; Fear; GABA-A Receptor Agonists; Haloperidol; Male; Rats; Rats, Wistar; Reflex, Startle; Sensitivity and Specificity; Strychnine

1998
Acute dystonic reactions to "street Xanax".
    The New England journal of medicine, 2002, May-30, Volume: 346, Issue:22

    Topics: Adolescent; Adult; Alprazolam; Child; Dystonia; Female; Haloperidol; Humans; Illicit Drugs; Male

2002
Dependence of the kinetic and thermodynamic parameters on hydrophilic-lipophilic character of alprazolam, clonazepam, diazepam, doxepin and haloperidol in alkaline environment.
    International journal of pharmaceutics, 2013, Oct-15, Volume: 455, Issue:1-2

    Topics: Alprazolam; Clonazepam; Diazepam; Doxepin; Drug Stability; Haloperidol; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kinetics; Thermodynamics

2013