haloperidol has been researched along with 1-methyl-4-phenylpyridinium in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (16.67) | 18.7374 |
| 1990's | 9 (50.00) | 18.2507 |
| 2000's | 3 (16.67) | 29.6817 |
| 2010's | 3 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Fang, J; Gorrod, JW | 1 |
| De Vries, JB; Duran, R; Westerink, BH | 1 |
| de Vries, JB; Hofsteede, RM; Tuntler, J; Westerink, BH | 1 |
| Autelitano, DJ; Funder, JW; Lolait, SJ; Smith, AI | 1 |
| Damsma, G; de Vries, JB; Rollema, H; Tuntler, J; Westerink, BH | 1 |
| Himori, N; Mishima, K | 1 |
| Bloomquist, J; Castagnoli, K; Castagnoli, N; Kimura, K; King, E; Mytilineou, C; Wright, A | 1 |
| Ablordeppey, SY; Borne, RF | 1 |
| Castagnoli, N; D'Engelbronner, J; Igarashi, K; Rollema, H; Skolnik, M; Usuki, E | 1 |
| Fang, J; Yu, PH; Zuo, D | 1 |
| Castagnoli, N; Fukui, M; Idzu, T; Igarashi, K; Kasuya, F; Matsubara, K | 1 |
| Ohta, S; Yamakawa, T | 1 |
| Gibson, K; Li, XM; Qing, H; Wei, Z; Xu, H | 1 |
| Kalgutkar, AS; Nguyen, HT | 1 |
| Kim, LW; Kim, YH; Lee, BJ; Lee, CH; Lee, JG; Park, SW; Shin, BS | 1 |
| de Pablos, RM; Espinosa-Oliva, AM; Santiago, M | 1 |
| Chen, KP; Lung, FW; Yang, MC | 1 |
18 other study(ies) available for haloperidol and 1-methyl-4-phenylpyridinium
| Article | Year |
|---|---|
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Dehydration is the first step in the bioactivation of haloperidol to its pyridinium metabolite.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Biotransformation; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Haloperidol; Male; Mice; Microsomes, Liver; Parkinson Disease, Secondary | 1991 |
Use of microdialysis for monitoring tyrosine hydroxylase activity in the brain of conscious rats.
Topics: 1-Methyl-4-phenylpyridinium; 4-Butyrolactone; alpha-Methyltyrosine; Animals; Apomorphine; Brain; Chromatography, High Pressure Liquid; Consciousness; Dialysis; Dihydroxyphenylalanine; Haloperidol; Male; Methyltyrosines; Monitoring, Physiologic; Rats; Rats, Inbred Strains; Tyrosine 3-Monooxygenase | 1990 |
Use of calcium antagonism for the characterization of drug-evoked dopamine release from the brain of conscious rats determined by microdialysis.
Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Calcium; Corpus Striatum; Dialysis; Dopamine; Glutamates; Glutamic Acid; Haloperidol; Magnesium; Male; Nomifensine; Ouabain; Piperazines; Potassium; Pyridinium Compounds; Rats; Rats, Inbred Strains; Tetrodotoxin | 1989 |
Dopaminergic agents differentially alter beta-endorphin processing patterns in the rat pituitary neurointermediate lobe.
Topics: 1-Methyl-4-phenylpyridinium; Animals; beta-Endorphin; Bromocriptine; Chromatography, High Pressure Liquid; Dopamine; Endorphins; Female; Haloperidol; Pituitary Gland, Anterior; Pyridinium Compounds; Radioimmunoassay; Rats; Rats, Inbred Strains | 1985 |
The use of tetrodotoxin for the characterization of drug-enhanced dopamine release in conscious rats studied by brain dialysis.
Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Corpus Striatum; Dialysis; Dopamine; Haloperidol; Homovanillic Acid; Male; Morphine; Neurotoxins; Nucleus Accumbens; Piperazines; Pyridinium Compounds; Rats; Rats, Inbred Strains; Septal Nuclei; Tetrodotoxin | 1987 |
The COMT inhibitor tolcapone potentiates the anticataleptic effect of Madopar in MPP(+)-lesioned mice.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Benserazide; Benzophenones; Catalepsy; Catechol O-Methyltransferase Inhibitors; Drug Combinations; Drug Synergism; Haloperidol; Kinetics; Levodopa; Male; Mice; Mice, Inbred C57BL; Nitrophenols; Tolcapone; Tyrosine | 1994 |
1-Methyl-4-phenylpyridinium-like neurotoxicity of a pyridinium metabolite derived from haloperidol: cell culture and neurotransmitter uptake studies.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Cells, Cultured; Dopamine; Female; Haloperidol; Pregnancy; Rats; Rats, Sprague-Dawley; Serotonin; Synaptosomes | 1994 |
Detection of a neurotoxic quaternary pyridinium metabolite in the liver of haloperidol-treated rats.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Haloperidol; Indicators and Reagents; Liver; Male; Oxalates; Pyridinium Compounds; Rana pipiens; Rats; Rats, Wistar | 1993 |
MPP(+)-like neurotoxicity of a pyridinium metabolite derived from haloperidol: in vivo microdialysis and in vitro mitochondrial studies.
Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dopamine; Haloperidol; Lactates; Lactic Acid; Male; Mice; Microdialysis; Mitochondria, Liver; Nervous System; Pyridinium Compounds; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, Serotonin; Serotonin | 1994 |
Comparison of cytotoxicity of a quaternary pyridinium metabolite of haloperidol (HP+) with neurotoxin N-methyl-4-phenylpyridinium (MPP+) towards cultured dopaminergic neuroblastoma cells.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Cell Line; Dose-Response Relationship, Drug; Haloperidol; MPTP Poisoning; Neuroblastoma; Neurotoxins; Parkinson Disease; Time Factors | 1995 |
Effect of a pyridinium metabolite derived from haloperidol on the activities of striatal tyrosine hydroxylase in freely moving rats.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Dihydroxyphenylalanine; Dopamine Agents; Enzyme Inhibitors; Haloperidol; Hydrazines; Hydroxyindoleacetic Acid; Male; Microdialysis; Neostriatum; Rats; Rats, Wistar; Tyrosine 3-Monooxygenase | 1996 |
Biosynthesis of a parkinsonism-preventing substance, 1-methyl-1,2,3,4-tetrahydroisoquinoline, is inhibited by parkinsonism-inducing compounds in rat brain mitochondrial fraction.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Antipsychotic Agents; Biogenic Amines; Carbolines; Haloperidol; Harmine; Isoquinolines; Male; Mitochondria; Neurotoxins; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Tetrahydroisoquinolines | 1999 |
The ability of atypical antipsychotic drugs vs. haloperidol to protect PC12 cells against MPP+-induced apoptosis.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Antipsychotic Agents; Apoptosis; Blotting, Northern; DNA Fragmentation; Enzyme Activation; Glycosylation; Haloperidol; Herbicides; Neurons; Neuroprotective Agents; PC12 Cells; Rats; RNA, Messenger; Superoxide Dismutase | 2003 |
Identification of an N-methyl-4-phenylpyridinium-like metabolite of the antidiarrheal agent loperamide in human liver microsomes: underlying reason(s) for the lack of neurotoxicity despite the bioactivation event.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Antidiarrheals; Bupropion; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dealkylation; Haloperidol; Humans; Hydroxylation; Ketoconazole; Loperamide; Male; Microsomes, Liver; NADP; Neurons; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Time Factors | 2004 |
Protective effects of atypical antipsychotic drugs against MPP(+)-induced oxidative stress in PC12 cells.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Antipsychotic Agents; Aripiprazole; bcl-2-Associated X Protein; Benzodiazepines; Blotting, Western; Cell Survival; Haloperidol; Herbicides; Olanzapine; Oxidative Stress; PC12 Cells; Piperazines; Quinolones; Rats; Reactive Oxygen Species; Superoxide Dismutase; Thiazoles | 2011 |
In vivo effect of apomorphine and haloperidol on MPP neurotoxicity.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Apomorphine; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine Antagonists; Haloperidol; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Microdialysis; Neuroprotective Agents; Neurotoxicity Syndromes; Rats; Rats, Wistar | 2014 |
Generalized estimating equation model and long-term exposure effect of antipsychotics on SH-SY5Y cells against oxidative stressors.
Topics: 1-Methyl-4-phenylpyridinium; Amyloid beta-Peptides; Antipsychotic Agents; Benzodiazepines; Cell Line, Tumor; Cell Survival; Glutathione; Haloperidol; Humans; Hydrogen Peroxide; Models, Biological; Neuroprotective Agents; Olanzapine; Oxidative Stress; Paliperidone Palmitate; Peptide Fragments; Protein Carbonylation; Risperidone | 2014 |