haloperidol has been researched along with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (24.24) | 18.7374 |
| 1990's | 12 (36.36) | 18.2507 |
| 2000's | 6 (18.18) | 29.6817 |
| 2010's | 6 (18.18) | 24.3611 |
| 2020's | 1 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Wesemann, W | 1 |
| Ablordeppey, SY; Borne, RF; Davis, WM | 1 |
| Fang, J; Gorrod, JW | 1 |
| Bruno, JP; Hadjiconstantinou, M; Weihmuller, FB | 3 |
| Gibb, JW; Hanson, GR; Matsuda, LA; Schmidt, CJ | 1 |
| Bruno, JP; Hadjiconstantinou, M; Neff, NH; Weihmuller, FB | 1 |
| Barnes, JC; Barnes, NJ; Barnes, NM; Costall, B; Domeney, AM; Naylor, RJ | 1 |
| Fuller, RW; Hemrick-Luecke, SK | 1 |
| Cohen, O; Globus, M; Melamed, E; Rosenthal, J; Uzzan, A | 1 |
| Sirinathsinghji, DJ | 1 |
| Hanani, M; Haskel, Y | 1 |
| Aosaki, T; Graybiel, AM; Kimura, M | 1 |
| Hadjiconstantinou, M; Hubble, JP; Neff, NH; Sylvia, CP; Wemlinger, TA | 1 |
| Fang, J; Yu, PH; Zuo, D | 1 |
| Castagnol, N; Parkinson, A; Pearce, R; Usuki, E | 1 |
| Schneider, JS | 1 |
| Cheng, JT; Lin, YS; Tsao, CW | 1 |
| Wu, WR; Zhu, XZ | 1 |
| Chambers, LK; Greenamyre, JT; Jaw-Tsai, SS; Menniti, FS; Steece-Collier, K | 1 |
| Bergh, JJ; Castagnoli, N; Mienie, LJ; Petzer, JP; Van der Schyf, CJ | 1 |
| D'Souza, UM; Eisch, AJ; Hwang, CK; Kim, YM; Lammers, CH; Lee, SH; Mouradian, MM; Nestler, EJ; Yajima, S; Yang, Y | 1 |
| Kalgutkar, AS; Nguyen, HT | 1 |
| Al-Barghouthy, G; Hagan, JJ; Jackson, MJ; Jenner, P; Pearce, RK; Smith, L | 1 |
| Billinton, A; Brown, M; Chapman, H; Quinn, LP; Stean, TO; Upton, N; Vidgeon-Hart, M; Virley, DJ | 1 |
| Ardashov, OV; Il'ina, IV; Karpova, EV; Korchagina, DV; Morozova, EA; Pavlova, AV; Salakhutdinov, NF; Tolstikova, TG; Volcho, KP | 1 |
| Bondarenko, NA; Gudasheva, TA; Povarnina, PY; Seredenin, SB; Vorontsova, ON | 1 |
| Battaglia, G; Bruno, V; Bucci, D; Cannella, M; Gradini, R; Molinaro, G; Motolese, M; Nicoletti, F | 1 |
| Jain, R; Meena, CL; Pant, AB; Rajput, SK; Sharma, AK; Sharma, SS | 1 |
| Aymerich, MS; Celorrio, M; Estella-Hermoso de Mendoza, A; Fernández-Suárez, D; Franco, R; Müller, CE; Oyarzábal, J; Ramírez, MJ; Rojo-Bustamante, E; Sáez, E | 1 |
| Adekenov, SM; Arystan, LI; Haydargalieva, LS; Muldaeva, GM; Nurmaganbetov, ZS | 1 |
| Kadiri, SK; Karkar, VV; Pal Roy, S; Rao Konijeti, S | 1 |
33 other study(ies) available for haloperidol and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
| Article | Year |
|---|---|
Therapy of Morbus Parkinson and radical-induced neurotoxicity in the rat--in vivo voltammetric studies.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Apomorphine; Corpus Striatum; Dopamine; Electrochemistry; Free Radicals; Haloperidol; Hydroxyindoleacetic Acid; Male; Memantine; Neurotoxins; Parkinson Disease; Rats; Rats, Wistar; Rotenone; Serotonin; Substantia Nigra | 1992 |
Freezing action of a metabolite of haloperidol in frogs.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Freezing; Haloperidol; Liver; Models, Biological; Oxidation-Reduction; Rana pipiens | 1992 |
Dehydration is the first step in the bioactivation of haloperidol to its pyridinium metabolite.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Biotransformation; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Haloperidol; Male; Mice; Microsomes, Liver; Parkinson Disease, Secondary | 1991 |
Dopamine receptors and sensorimotor behavior in MPTP-treated mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Arousal; Benzazepines; Discrimination Learning; Dopamine Agents; Dopamine Antagonists; Dose-Response Relationship, Drug; Ergolines; Haloperidol; Male; Mice; Mice, Inbred Strains; Motor Activity; Orientation; Quinpirole; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Sulpiride | 1990 |
Dissociation between biochemical and behavioral recovery in MPTP-treated mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Benzazepines; Corpus Striatum; Dopamine; Dopamine Antagonists; Drug Interactions; Haloperidol; Male; Mice; Phenylacetates; Psychomotor Performance; Sulpiride; Time Factors | 1989 |
Effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on striatal tyrosine hydroxylase and tryptophan hydroxylase in rat.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Haloperidol; Homovanillic Acid; Kinetics; Male; Neurotoxins; Pyridines; Rats; Rats, Inbred Strains; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase | 1986 |
Administration of GM1 ganglioside eliminates neuroleptic-induced sensorimotor deficits in MPTP-treated mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antipsychotic Agents; Behavior, Animal; Corpus Striatum; Dopamine; G(M1) Ganglioside; Haloperidol; Male; Mice; Movement Disorders; Pyridines | 1988 |
Ketotifen can antagonise changes in sensitivity of cerebral dopamine receptors: behavioural correlates in rodent and primate.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Behavior, Animal; Brain; Callitrichinae; Catalepsy; Dopamine; Dopamine Antagonists; Haloperidol; Injections; Ketotifen; Levodopa; Male; Motor Activity; Nucleus Accumbens; Pyridines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior | 1987 |
Acute stress or neuroleptics elicit sensorimotor deficits in MPTP-treated mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Cold Temperature; Corpus Striatum; Dopamine; Haloperidol; Injections, Intraperitoneal; Male; Mice; Psychomotor Disorders; Pyridines; Stress, Physiological | 1988 |
Effects of amfonelic acid, alpha-methyltyrosine, Ro 4-1284 and haloperidol pretreatment on the depletion of striatal dopamine by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-; alpha-Methyltyrosine; Animals; Corpus Striatum; Dopamine; Haloperidol; Male; Methyltyrosines; Mice; Mice, Inbred Strains; Nalidixic Acid; Naphthyridines; Pyridines | 1985 |
Suppression of MPTP-induced dopaminergic neurotoxicity in mice by nomifensine and L-DOPA.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Bromocriptine; Corpus Striatum; Dopamine; Haloperidol; Levodopa; Male; Mice; Mice, Inbred C57BL; Nomifensine; Pyridines | 1985 |
Behavioural effects in the rat after acute unilateral intranigral infusions of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Dextroamphetamine; Drug Interactions; Female; Haloperidol; Hydroxydopamines; Motor Activity; Oxidopamine; Pargyline; Picrotoxin; Pyridines; Rats; Rotation; Substantia Nigra | 1985 |
Inhibition of gastrointestinal motility by MPTP via adrenergic and dopaminergic mechanisms.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Dopamine; Gastrointestinal Motility; Haloperidol; Isoproterenol; Male; Mice; Mice, Inbred BALB C; Pargyline; Phentolamine; Propranolol; Receptors, Adrenergic | 1994 |
Effect of the nigrostriatal dopamine system on acquired neural responses in the striatum of behaving monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Action Potentials; Animals; Apomorphine; Behavior, Animal; Conditioning, Classical; Corpus Striatum; Dopamine; Haloperidol; Macaca; Male; Neuronal Plasticity; Neurons; Substantia Nigra | 1994 |
Aromatic L-amino acid decarboxylase activity of mouse striatum is modulated via dopamine receptors.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Aromatic-L-Amino-Acid Decarboxylases; Benzazepines; Bromocriptine; Corpus Striatum; Cycloheximide; Dopamine Antagonists; Haloperidol; Kinetics; Levodopa; Male; Mice; Pyridoxal Phosphate; Receptors, Dopamine; Reserpine; Sulpiride; Time Factors | 1993 |
Comparison of cytotoxicity of a quaternary pyridinium metabolite of haloperidol (HP+) with neurotoxin N-methyl-4-phenylpyridinium (MPP+) towards cultured dopaminergic neuroblastoma cells.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Cell Line; Dose-Response Relationship, Drug; Haloperidol; MPTP Poisoning; Neuroblastoma; Neurotoxins; Parkinson Disease; Time Factors | 1995 |
Studies on the conversion of haloperidol and its tetrahydropyridine dehydration product to potentially neurotoxic pyridinium metabolites by human liver microsomes.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antibodies; Antipsychotic Agents; Calibration; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Haloperidol; Humans; Kinetics; Microsomes, Liver; Oxidation-Reduction; Pyridinium Compounds; Rats; Spectrometry, Fluorescence; Steroid Hydroxylases | 1996 |
Preservation of autoreceptor-mediated increases in dopamine synthesis in aged mice with experimentally-induced parkinsonism.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Autoreceptors; Dihydroxyphenylalanine; Dopamine; Dopamine Antagonists; Haloperidol; Male; Mice; Mice, Inbred C57BL; Neurons; Parkinson Disease, Secondary; Tyrosine 3-Monooxygenase | 1997 |
Inhibition of immune cell proliferation with haloperidol and relationship of tyrosine hydroxylase expression to immune cell growth.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Methyltyrosine; Animals; Cell Division; Dopamine Agents; Dopamine Antagonists; Enzyme Inhibitors; Flow Cytometry; Gene Expression; Haloperidol; Humans; Hybridomas; Mice; PC12 Cells; Rats; T-Lymphocytes; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase | 1998 |
The amphetamine-like reinforcing effect and mechanism of L-deprenyl on conditioned place preference in mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amphetamine; Animals; Conditioning, Operant; Corpus Striatum; Dopamine; Dopamine Agents; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Haloperidol; Mice; Mice, Inbred C57BL; Monoamine Oxidase Inhibitors; Reinforcement, Psychology; Selegiline | 1999 |
Antiparkinsonian actions of CP-101,606, an antagonist of NR2B subunit-containing N-methyl-d-aspartate receptors.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Behavior, Animal; Catalepsy; Dopamine Agents; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Female; Haloperidol; Levodopa; Macaca mulatta; Male; Parkinson Disease, Secondary; Piperidines; Rats; Rats, Inbred F344; Reaction Time; Receptors, N-Methyl-D-Aspartate | 2000 |
Metabolic defects caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and by HPTP (the tetrahydropyridinyl analog of haloperidol), in rats.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antipsychotic Agents; Haloperidol; Lactic Acid; Male; Metabolism, Inborn Errors; Mitochondria; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Valerates | 2000 |
Dopamine receptor regulating factor, DRRF: a zinc finger transcription factor.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amino Acid Sequence; Animals; Autoradiography; Brain; Cell Line; Cocaine; Conserved Sequence; Corpus Striatum; Dopamine; Dopamine Antagonists; Down-Regulation; Gene Expression Regulation; Haloperidol; In Situ Hybridization; Kruppel-Like Transcription Factors; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Neuroblastoma; Neurons; Receptors, Dopamine; RNA, Messenger; Sequence Alignment; Sequence Homology, Amino Acid; Transcription Factors; Transfection; Tumor Cells, Cultured; Zinc Fingers | 2001 |
Identification of an N-methyl-4-phenylpyridinium-like metabolite of the antidiarrheal agent loperamide in human liver microsomes: underlying reason(s) for the lack of neurotoxicity despite the bioactivation event.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Antidiarrheals; Bupropion; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dealkylation; Haloperidol; Humans; Hydroxylation; Ketoconazole; Loperamide; Male; Microsomes, Liver; NADP; Neurons; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Time Factors | 2004 |
Effect of 5-HT1B/D receptor agonist and antagonist administration on motor function in haloperidol and MPTP-treated common marmosets.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Callithrix; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Female; Haloperidol; Male; Motor Activity; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2004 |
Further validation of LABORAS using various dopaminergic manipulations in mice including MPTP-induced nigro-striatal degeneration.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amphetamine; Animals; Apomorphine; Automation; Behavior, Animal; Benzazepines; Brain Chemistry; Chromatography, High Pressure Liquid; Dopamine Agents; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Electrochemistry; Haloperidol; Hyperkinesis; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Motor Activity; Neostriatum; Nerve Degeneration; Psychology, Experimental; Reproducibility of Results; Substantia Nigra | 2006 |
Highly potent activity of (1R,2R,6S)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol in animal models of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Cyclohexanols; Disease Models, Animal; Dopamine Antagonists; Drug Synergism; Haloperidol; Levodopa; Mice; Mice, Inbred C57BL; Molecular Conformation; Motor Activity; Neurotoxins; Parkinson Disease; Parkinsonian Disorders; Rats; Rats, Wistar; Receptors, Neurotransmitter; Stereoisomerism | 2011 |
Antiparkinsonian properties of a nerve growth factor dipeptide mimetic GK-2 in in vivo experiments.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Catalepsy; Dipeptides; Haloperidol; Male; Mice; Mice, Inbred C57BL; Oxidopamine; Parkinsonian Disorders; Rats | 2011 |
Changes in the expression of genes encoding for mGlu4 and mGlu5 receptors and other regulators of the indirect pathway in acute mouse models of drug-induced parkinsonism.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Acute Disease; Animals; Catalepsy; Corpus Striatum; Enkephalins; Haloperidol; Mice, Inbred C57BL; Mice, Knockout; Neurons; Parkinsonian Disorders; Protein Precursors; Proto-Oncogene Proteins c-fos; Receptor, Cannabinoid, CB1; Receptor, Metabotropic Glutamate 5; Receptors, Adenosine A2; Receptors, Metabotropic Glutamate; Time Factors; Ventral Thalamic Nuclei | 2015 |
Effect of L-pGlu-(1-benzyl)-l-His-l-Pro-NH
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain Ischemia; Catalepsy; Cell Death; Disease Models, Animal; Glucose; Glutamic Acid; Haloperidol; Hippocampus; Inflammation Mediators; Lipid Peroxidation; Male; Memory Disorders; Mice; Models, Biological; Motor Activity; Neurons; Oxygen; PC12 Cells; Rats; Scopolamine; Thyrotropin-Releasing Hormone | 2016 |
GPR55: A therapeutic target for Parkinson's disease?
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Basal Ganglia; Calcium-Binding Proteins; Cannabidiol; Cannabinoid Receptor Agonists; Catalepsy; Corpus Striatum; Dopamine; Haloperidol; Homovanillic Acid; Male; Mice, Inbred C57BL; Microfilament Proteins; Neurons; Parkinsonian Disorders; Receptors, Cannabinoid; RNA, Messenger | 2017 |
Experimental study of antiparkinsonian action of the harmine hydrochloride original compound.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Catalepsy; Haloperidol; Harmine; Levodopa; Male; Mice; Mice, Inbred C57BL; Parkinsonian Disorders; Rats | 2019 |
Antiparkinsonian activity of Tabebuia impetiginosa bark and biochemical analysis of dopamine in rat brain homogenates.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adjuvants, Immunologic; Animals; Antioxidants; Antiparkinson Agents; Antipsychotic Agents; Apomorphine; Brain; Catalepsy; Catatonia; Dopamine; Haloperidol; Hypokinesia; Muscle Rigidity; Plant Bark; Rats; Reserpine; Tabebuia; Tremor; Water | 2022 |