Page last updated: 2024-08-23

halofantrine and quinine

halofantrine has been researched along with quinine in 80 studies

Research

Studies (80)

Timeframe	Studies, this research(%)	All Research%
pre-1990	7 (8.75)	18.7374
1990's	49 (61.25)	18.2507
2000's	18 (22.50)	29.6817
2010's	6 (7.50)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Craig, PN; Fukunaga, JY; Hansch, C; Jow, PY; Kim, KH; Page, J; Steller, EE	1
Jomaa, H; Mitsch, A; Schlitzer, M; Wiesner, J; Wissner, P	1
Egan, TJ; Hoppe, HC; Joiner, KA; Roberts, L	1
Bambal, RB; Bates, M; Berry, N; Biagini, GA; Bonar-Law, R; Bray, PG; Brigandi, RA; Davis, CB; Gargallo, DV; Gibbons, P; Gomez-delas-Heras, FM; Gresham, SL; Hart, TK; Hindley, S; Lawrence, RM; Maggs, JL; Mukhtar, A; O'Neill, PM; Park, BK; Roberts, P; Shone, AE; Stocks, PA; Ward, SA; Winstanley, PA	1
Masseno, V; Muriithi, S; Nzila, A	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Badoual, J	1
Chutmongkonkul, M; Maier, WA; Seitz, HM	1
Baziomo, JM; Gendrel, C; Gendrel, D; Kombila, M; Lecointre, C; Martz, M; Nardou, M; Richard-Lenoble, D	1
Fadat, G; Gardon, J; Gazin, P; Hengy, C; Jambou, R; Louis, FJ; Louis, JP; Trebucq, A	1
Bustos, MD; Ciceron, L; Danis, M; Gay, F; Gentilini, M; Pichet, C; Rojas-Rivero, L	1
Basco, LK; Bouchaud, O; Coulaud, JP; Farinotti, R; Gillotin, C; Gimenez, F; Le Bras, J; Rabenjarson, E; Ringwald, P	1
Baudon, D; Cordoliani, G; Da Conceicao, S; Delolme, H; Doury, JC; Hovette, P; Lecamus, JL; Martet, G; Raphenon, G; Touze, JE	1
Trigg, PI	1
Bourdeau, EF; Childs, GE; Milhous, WK; Pang, L; Wimonwattratee, T	1
Le Bras, M; Mazaudier, E; Raccurt, CP; Ripert, C; Schmitt, A	1
Jeandel, P; Touze, JE	1
Childs, GE; Pooyindee, N; Wimonwattrawatee, T	1
Boudreau, EF; Pang, LW; Pavanand, K; Webster, HK; Yongvanitchit, K	1
Canfield, CJ; Cosgriff, TM; Pamplin, CL; Willet, GP	1
Coulanges, P; Deloron, P; Le Bras, J; Ramanamirija, JA	1
Biaud, JM; Coulanges, P; Deloron, P; Le Bras, J; Ramanamirija, JA	1
Coulanges, P; Coulaud, JP; Deloron, P; Le Bras, J	1
Eichenlaub, D; Jelinek, T; Löscher, T; Schelbert, P	1
Ager, A; Andersen, SL; Berman, J; Ellis, W; Kuschner, R; McGreevy, P; Ohrt, C; Rossan, R; Schuster, BG; Wesche, D	1
Basco, LK; Le Bras, J; Makler, MM; Marquet, F	1
Edwards, G; Ward, SA; Winstanley, PA	1
Baric, RS; Bright, P; Handy, J; Peel, SA; Yount, B	1
Basco, LK; Le Bras, J	2
Fleckenstein, L; Jongsakul, K; Karnasuta, C; Loesuttiviboon, L; Ohrt, CK; Schuster, B; Shanks, GD; Watt, G	1
Basco, LK; Le Bras, J; Ramiliarisoa, O	1
Cowman, AF; Galatis, D; Thompson, JK	1
Marsh, K; Watkins, WM; Woodrow, C	1
Go, ML; Lee, HS; Ngiam, TL	1
Baric, RS; Handy, J; Merritt, SC; Peel, SA	1
Touze, JE	1
Angus, B; Bates, I; Krishna, S; Kyle, DE; Pipitaporn, B; Pukrittayakamee, S; Suputtamongkol, Y; Udomsangpetch, R; White, NJ	1
Abecassis, L; Adam, MN; Baledent, F; Caillet, R; Giacomini, T; Le Bras, J; Poupin, F	1
Brault, M; Delling, U; Gros, P; Ruetz, S; Schurr, E	1
Bray, PG; Green, JE; Hawley, SR; Mungthin, M; Ritchie, GY; Ward, SA	1
Karle, JM	1
Gorge, O; Nicolas, F; Nicolas, X; Perret, JL; Touze, JE	1
Pillans, PI; Tish, KN	1
Doury, JC; Fusai, T; Pradines, B; Rogier, C; Tall, A; Trape, JF	1
Kremsner, PG; Philipps, J; Radloff, PD; Wernsdorfer, W	1
Coulibaly, SO; Dutheil, Y; Guiguemdé, TR; Ouédraogo, JB; Tall, F; Tinto, H; Traoré, B; Zampa, H	1
Clerinx, J; Colebunders, R; Coppens, G; Depraetere, K; Peetermans, WE; Schroyens, W; Van den Ende, J; Van den Enden, E; Van Gompel, A; Van Haegenborgh, T; Verstraeten, T	1
Graffin, B; Kraemer, P; Molinier, S; Perret, JL; Sane, M	1
Doury, JC; Kombila, M; Lebeau, C; Mabika Mamfoumbi, M; Mourou Mbina, JR; Owono Medang, M; Parzy, D; Pradines, B	2
Backmund, M; Eichenlaub, D; Hartmann, WJ; Hesse, J; von Zielonka, M	1
Bourgeade, A; Delmont, J	1
Burgel, PR; Camara, P; Hovette, P; Klotz, F; Mbaye, PS; Sane, M	1
Chongsuphajaisiddhi, T; Luxemburger, C; Nosten, F; Phaipun, L; Price, R; Simpson, JA; ter Kuile, F; van Vugt, M; White, NJ	1
Bray, PG; Mungthin, M; Ward, SA	1
Lial, JP	1
Danis, M; Delhaes, L; Gay, F; Lazaro, JE; Thellier, M	1
Duraisingh, MT; Jones, P; Pinder, M; Sambou, I; von Seidlein, L; Warhurst, DC	1
Caruana, SR; Cowman, AF; Kirk, K; Reed, MB; Saliba, KJ	1
Makonnen, E; Mengesha, T	1
Danis, M; Gay, F; Khusmith, S; Looareesuwan, S; Muanza, K; Supavej, S; Traoré, B; Viriyavejakul, P	1
Hombhanje, FW	1
Bockarie, MJ; Gbakima, AA; Sahr, F; Willoughby, VR	1
Beytout, J; Caumon, L; Chouaki, M; Cueto, T; Delort, P; Dufraise, S; Monchard, F; Philippe, JM; Rimeize, H	1
Bedos, JP; Bruneel, F; Danis, M; Gachot, B; Regnier, B; Vachon, F; Wolff, M	1
Alberti, C; Bédos, JP; Bruneel, F; Chevret, S; Durand, R; Hocqueloux, L; Le Bras, J; Régnier, B; Vachon, F; Wolff, M	1
Atteke, C; Aubouy, A; Bakary, M; Deloron, P; Lébibi, J; Ndong, JM	1
Jambou, R; Randrianarijaona, A; Randrianarivelojosia, M; Randrianasolo, L; Ratsimbasoa, A	1
Nakajima, Y	1
Brown, ML; Geyer, JA; Terrell, JC; Trotta, RF	1
Beg, MA; Khan, MA; Razi, ST; Smego, RA	1
Fidock, DA; Sidhu, AB; Valderramos, SG	1
Fidock, DA; Krishna, S; Sidhu, AB; Uhlemann, AC; Valderramos, JC; Valderramos, SG	1
Abuaku, B; Duah, NO; Koram, KA; Quashie, NB	1
Borrmann, S; Kiara, SM; Mwai, L; Nzila, A; Ochola, LI; Ohuma, E; Okombo, J; Pole, L; Rono, J	1
Kimura, M; Kinoshita, A; Kotaki, H; Yamada, H	1
Assi, SB; Basco, LK; Bla, KB; Djaman, AJ; Koné, M; Mazabraud, A; Yavo, W	1
Berger, F; Bertani, S; Bouchier, C; Ekala, MT; Legrand, E; Mercereau-Puijalon, O; Meynard, JB; Musset, L; Péneau, J; Volney, B; Yrinesi, J	1
Abdel-Aal Sabra, AN; El-Lakkany, NM; Hammam, OA; Seif El-Din, SH	1

Reviews

5 review(s) available for halofantrine and quinine

Article	Year
Clinical pharmacokinetics in the treatment of tropical diseases. Some applications and limitations. Clinical pharmacokinetics, 1994, Volume: 27, Issue:2 Topics: Chloroquine; Diethylcarbamazine; Drug Resistance; Echinococcosis; Filariasis; Humans; Malaria; Mefloquine; Pharmacokinetics; Phenanthrenes; Pyrimethamine; Quinine; Sulfadoxine; Tropical Medicine	1994
[Correct usage of amino alcohols]. Medecine tropicale : revue du Corps de sante colonial, 1995, Volume: 55, Issue:3 Suppl Topics: Antimalarials; Clinical Protocols; Drug Administration Schedule; Drug Resistance; Humans; Malaria; Mefloquine; Phenanthrenes; Quinine	1995
Comparative efficacy and safety of chloroquine and alternative antimalarial drugs: a meta-analysis from six African countries. East African medical journal, 1999, Volume: 76, Issue:6 Topics: Africa, Eastern; Africa, Western; Amodiaquine; Antimalarials; Chloroquine; Drug Combinations; Drug Costs; Humans; Malaria; Mefloquine; Patient Selection; Phenanthrenes; Pyrimethamine; Quinine; Safety; Sulfadoxine; Treatment Outcome	1999
[Antiprotozoal drugs]. Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 2 Topics: Animals; Antiprotozoal Agents; Drug Combinations; Emetine; Humans; Mefloquine; Metronidazole; Phenanthrenes; Primaquine; Protozoan Infections; Pyrimethamine; Quinine; Sulfadoxine; Tinidazole	2003
Emerging drug--resistance and guidelines for treatment of malaria. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2004, Volume: 14, Issue:5 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance, Multiple; Drug Therapy, Combination; Follow-Up Studies; Humans; Malaria, Falciparum; Pakistan; Phenanthrenes; Plasmodium falciparum; Quinidine; Quinine; Sesquiterpenes; Time Factors	2004

Trials

1 trial(s) available for halofantrine and quinine

Article	Year
Efficacy and tolerance of extended-dose halofantrine for drug-resistant falciparum malaria in Thailand. The American journal of tropical medicine and hygiene, 1994, Volume: 50, Issue:2 Topics: Adult; Animals; Chi-Square Distribution; Diarrhea; Dizziness; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Male; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Tetracycline; Thailand; Vomiting	1994

Article

Year

Efficacy and tolerance of extended-dose halofantrine for drug-resistant falciparum malaria in Thailand.

The American journal of tropical medicine and hygiene, 1994, Volume: 50, Issue:2

Topics: Adult; Animals; Chi-Square Distribution; Diarrhea; Dizziness; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Male; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Tetracycline; Thailand; Vomiting

1994

Other Studies

74 other study(ies) available for halofantrine and quinine

Article	Year
Quantitative structure-activity relationships in 1-aryl-2-(alkylamino)ethanol antimalarials. Journal of medicinal chemistry, 1979, Volume: 22, Issue:4 Topics: Animals; Antimalarials; Ethanolamines; Malaria; Mice; Models, Biological; Phenanthrenes; Plasmodium berghei; Pyridines; Quinolines; Structure-Activity Relationship	1979
Structure-activity relationships of novel anti-malarial agents. Part 2: cinnamic acid derivatives. Bioorganic & medicinal chemistry letters, 2001, Feb-12, Volume: 11, Issue:3 Topics: Animals; Antimalarials; Cinnamates; Combinatorial Chemistry Techniques; Inhibitory Concentration 50; Microbial Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship	2001
Differential effects of quinoline antimalarials on endocytosis in Plasmodium falciparum. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:5 Topics: Amodiaquine; Animals; Antimalarials; Blotting, Western; Chloroquine; Endocytosis; Erythrocytes; Hemoglobins; Humans; Mefloquine; Peroxidase; Phenanthrenes; Plasmodium falciparum; Protein Binding; Protozoan Proteins; Quinolines	2008
Candidate selection and preclinical evaluation of N-tert-butyl isoquine (GSK369796), an affordable and effective 4-aminoquinoline antimalarial for the 21st century. Journal of medicinal chemistry, 2009, Mar-12, Volume: 52, Issue:5 Topics: Aminoquinolines; Amodiaquine; Animals; Antimalarials; Benzylamines; Cytochrome P-450 Enzyme Inhibitors; Dogs; Drug Evaluation, Preclinical; Drug Resistance; Female; Haplorhini; Heme; Humans; Malaria; Mice; Models, Molecular; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Rats; Structure-Activity Relationship	2009
In vitro chemosensitization of Plasmodium falciparum to antimalarials by verapamil and probenecid. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:7 Topics: Adjuvants, Pharmaceutic; Animals; Antimalarials; Parasitic Sensitivity Tests; Plasmodium falciparum; Probenecid; Verapamil	2009
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
[Treatment of malaria in children in France]. Pediatrie, 1992, Volume: 47, Issue:5 Topics: Antimalarials; Child; Chloroquine; France; Humans; Malaria, Cerebral; Malaria, Falciparum; Mefloquine; Phenanthrenes; Quinine	1992
A new model for testing gametocytocidal effects of some antimalarial drugs on Plasmodium falciparum in vitro. Annals of tropical medicine and parasitology, 1992, Volume: 86, Issue:3 Topics: Animals; Anopheles; Antimalarials; Chloroquine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; In Vitro Techniques; Models, Biological; Phenanthrenes; Plasmodium falciparum; Pyrimethamine; Quinine	1992
[Parasitemia in Plasmodium falciparum malarial attacks in children]. Presse medicale (Paris, France : 1983), 1992, Nov-14, Volume: 21, Issue:38 Topics: Adolescent; Antimalarials; Carrier State; Child; Child, Preschool; Gabon; Humans; Malaria, Falciparum; Phenanthrenes; Quinine; Seizures, Febrile	1992
Proposals for a new therapeutic strategy for simple Plasmodium falciparum malaria attacks in Cameroon. Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1992, Volume: 43, Issue:2 Topics: Administration, Oral; Aminoquinolines; Amodiaquine; Animals; Antimalarials; Cameroon; Child; Child, Preschool; Chloroquine; Drug Resistance; Humans; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine	1992
Mefloquine-halofantrine cross-resistance in Plasmodium falciparum induced by intermittent mefloquine pressure. The American journal of tropical medicine and hygiene, 1992, Volume: 47, Issue:3 Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Humans; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine	1992
Type RI resistance to halofantrine in West Africa. Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1991, Volume: 42, Issue:4 Topics: Animals; Antimalarials; Biological Availability; Chloroquine; Cote d'Ivoire; Drug Resistance; Follow-Up Studies; France; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Phenanthrenes; Plasmodium falciparum; Quinine; Recurrence; Travel	1991
[Malaria in the republic of São Tomé and Principe. Epidemiologic evaluation and chemoresistance of P. falciparum]. Bulletin de la Societe de pathologie exotique (1990), 1991, Volume: 84, Issue:3 Topics: Age Factors; Animals; Antimalarials; Atlantic Islands; Child; Child, Preschool; Chloroquine; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Seasons; Sex Factors; Splenomegaly	1991
Drug use and design in the nineties. Acta Leidensia, 1991, Volume: 60, Issue:1 Topics: Aminoquinolines; Amodiaquine; Antimalarials; Artemisinins; Calcium Channel Blockers; Chloroquine; Humans; Malaria; Mefloquine; Naphthoquinones; Phenanthrenes; Primaquine; Quinine; Sesquiterpenes; Sulfadoxine	1991
In vitro and clinical correlates of mefloquine resistance of Plasmodium falciparum in eastern Thailand. The American journal of tropical medicine and hygiene, 1991, Volume: 44, Issue:5 Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Butylated Hydroxytoluene; Chloroquine; Drug Resistance; Drugs, Chinese Herbal; Mefloquine; Molecular Structure; Phenanthrenes; Plasmodium falciparum; Pyridines; Pyrimethamine; Quinine; Sesquiterpenes; Thailand	1991
[Imported malaria in Bordeaux in 1989. Epidemiologic, clinical and therapeutic study of 71 cases]. Bulletin de la Societe de pathologie exotique (1990), 1990, Volume: 83, Issue:5 Topics: Animals; Antimalarials; Chloroquine; Female; France; Humans; Malaria; Male; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Travel	1990
[Clinical and therapeutic approach in Plasmodium falciparum malaria in non-immune patients]. Presse medicale (Paris, France : 1983), 1990, Apr-14, Volume: 19, Issue:15 Topics: Animals; Drug Resistance, Microbial; Humans; Malaria; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine	1990
Evaluation of an in vitro assay system for drug susceptibility of field isolates of Plasmodium falciparum from southern Thailand. The American journal of tropical medicine and hygiene, 1988, Volume: 38, Issue:1 Topics: Amodiaquine; Animals; Antimalarials; Butylated Hydroxytoluene; Chloroquine; Humans; Mefloquine; Parasitology; Phenanthrenes; Plasmodium falciparum; Pyridines; Pyrimethamine; Quinine; Quinolines; Thailand; Triazines	1988
Antimalarial drug susceptibility testing of Plasmodium falciparum in Thailand using a microdilution radioisotope method. The American journal of tropical medicine and hygiene, 1985, Volume: 34, Issue:2 Topics: Adult; Animals; Antimalarials; Chloroquine; Drug Resistance, Microbial; Humans; Lethal Dose 50; Malaria; Male; Mefloquine; Microbial Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Quinine; Quinolines; Thailand	1985
Mefloquine failure in a case of falciparum malaria induced with a multidrug-resistant isolate in a non-immune subject. The American journal of tropical medicine and hygiene, 1985, Volume: 34, Issue:4 Topics: Adult; Antimalarials; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Male; Mefloquine; Phenanthrenes; Plasmodium falciparum; Pyridines; Quinine; Quinolines	1985
Plasmodium falciparum in Madagascar: in vivo and in vitro sensitivity to seven drugs. Annals of tropical medicine and parasitology, 1985, Volume: 79, Issue:4 Topics: Adolescent; Adult; Aged; Amodiaquine; Antimalarials; Child; Child, Preschool; Chloroquine; Humans; Infant; Madagascar; Malaria; Mefloquine; Microbial Sensitivity Tests; Middle Aged; Phenanthrenes; Piperazines; Plasmodium falciparum; Quinine; Quinolines	1985
[In vivo and in vitro sensitivity to 4-aminoquinolines of Plasmodium falciparum in Madagascar: results of 2 years' study]. Bulletin de la Societe de pathologie exotique et de ses filiales, 1985, Volume: 78, Issue:5 Topics: Aminoquinolines; Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Resistance, Microbial; Humans; In Vitro Techniques; Madagascar; Malaria; Phenanthrenes; Piperazines; Plasmodium falciparum; Quinine; Quinolines	1985
[Drug sensitivity of Plasmodium falciparum in Madagascar. V. Study of the in vitro activity of quinine, mefloquine and halofantrine]. Archives de l'Institut Pasteur de Madagascar, 1984, Volume: 51, Issue:1 Topics: Antimalarials; Chloroquine; Humans; Mefloquine; Microbial Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Quinine; Quinolines	1984
Quinine resistant falciparum malaria acquired in east Africa. Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1995, Volume: 46, Issue:1 Topics: Adult; Africa, Eastern; Animals; Antimalarials; Chloroquine; Drug Resistance; Humans; Malaria, Falciparum; Male; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Tetracycline	1995
Activity of azithromycin as a blood schizonticide against rodent and human plasmodia in vivo. The American journal of tropical medicine and hygiene, 1995, Volume: 52, Issue:2 Topics: Administration, Oral; Animals; Antimalarials; Aotus trivirgatus; Artemisinins; Azithromycin; Disease Models, Animal; Doxycycline; Drug Therapy, Combination; Humans; Injections, Subcutaneous; Malaria; Malaria, Falciparum; Mice; Parasitemia; Phenanthrenes; Plasmodium berghei; Quinine; Sesquiterpenes	1995
Plasmodium falciparum and Plasmodium vivax: lactate dehydrogenase activity and its application for in vitro drug susceptibility assay. Experimental parasitology, 1995, Volume: 80, Issue:2 Topics: Animals; Antimalarials; Chloroquine; Colorimetry; Erythrocytes; Humans; L-Lactate Dehydrogenase; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Parasitemia; Phenanthrenes; Plasmodium falciparum; Plasmodium vivax; Quinine	1995
A strong association between mefloquine and halofantrine resistance and amplification, overexpression, and mutation in the P-glycoprotein gene homolog (pfmdr) of Plasmodium falciparum in vitro. The American journal of tropical medicine and hygiene, 1994, Volume: 51, Issue:5 Topics: Animals; Antimalarials; Artemisinins; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Blotting, Northern; Blotting, Southern; Chloroquine; DNA Primers; DNA, Protozoan; Drug Resistance; Gene Amplification; Gene Expression; Genes, Protozoan; Mefloquine; Molecular Sequence Data; Phenanthrenes; Plasmodium falciparum; Point Mutation; Polymerase Chain Reaction; Quinine; RNA, Messenger; Selection, Genetic; Sequence Homology, Nucleic Acid; Sesquiterpenes	1994
In vitro susceptibility of Cambodian isolates of Plasmodium falciparum to halofantrine, pyronaridine and artemisinin derivatives. Annals of tropical medicine and parasitology, 1994, Volume: 88, Issue:2 Topics: Adult; Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Humans; In Vitro Techniques; Mefloquine; Naphthyridines; Phenanthrenes; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine; Sesquiterpenes; Triazines	1994
In vitro activity of pyrimethamine, cycloguanil, and other antimalarial drugs against African isolates and clones of Plasmodium falciparum. The American journal of tropical medicine and hygiene, 1994, Volume: 50, Issue:2 Topics: Africa; Animals; Antimalarials; Chloroquine; Drug Resistance; Humans; Mefloquine; Phenanthrenes; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine; Triazines	1994
Selection for mefloquine resistance in Plasmodium falciparum is linked to amplification of the pfmdr1 gene and cross-resistance to halofantrine and quinine. Proceedings of the National Academy of Sciences of the United States of America, 1994, Feb-01, Volume: 91, Issue:3 Topics: Animals; Chromosome Mapping; Drug Resistance; Gene Amplification; Gene Expression; Genes, Protozoan; Humans; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine	1994
Falciparum malaria: differential effects of antimalarial drugs on ex vivo parasite viability during the critical early phase of therapy. The American journal of tropical medicine and hygiene, 1993, Volume: 49, Issue:1 Topics: Animals; Antimalarials; Drug Combinations; Drug Therapy, Combination; Humans; Malaria, Falciparum; Phenanthrenes; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine; Time Factors	1993
In vitro activity of artemisinin derivatives against African isolates and clones of Plasmodium falciparum. The American journal of tropical medicine and hygiene, 1993, Volume: 49, Issue:3 Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Drug Resistance; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Sesquiterpenes	1993
Pharmacological activity and structure-activity relationship of (+/-)-erythro-mefloquine and related compounds on the isolated mouse phrenic nerve diaphragm preparation. Biological & pharmaceutical bulletin, 1993, Volume: 16, Issue:7 Topics: Animals; Antimalarials; Bungarotoxins; Electric Stimulation; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Mefloquine; Mice; Models, Molecular; Molecular Conformation; Muscle Contraction; Neuromuscular Junction; Phenanthrenes; Phrenic Nerve; Quinine; Quinolines; Structure-Activity Relationship	1993
Derivation of highly mefloquine-resistant lines from Plasmodium falciparum in vitro. The American journal of tropical medicine and hygiene, 1993, Volume: 48, Issue:3 Topics: Animals; Antimalarials; Chloroquine; Dose-Response Relationship, Drug; Drug Resistance; Erythrocytes; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Serial Passage; Vacuoles	1993
Antimalarial drugs reduce cytoadherence and rosetting Plasmodium falciparum. The Journal of infectious diseases, 1996, Volume: 173, Issue:3 Topics: Adolescent; Adult; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Cell Adhesion; Erythrocytes; Humans; In Vitro Techniques; Malaria, Falciparum; Middle Aged; Phenanthrenes; Plasmodium falciparum; Quinine; Rosette Formation; Sesquiterpenes	1996
[Diagnostic and prognostic importance of laboratory tests in malaria in airports. Study of six recent cases]. Pathologie-biologie, 1996, Volume: 44, Issue:4 Topics: Adult; Aerospace Medicine; Antimalarials; Chloroquine; Female; France; Humans; Malaria, Falciparum; Male; Microbiological Techniques; Middle Aged; Phenanthrenes; Platelet Count; Prognosis; Quinine	1996
The pfmdr1 gene of Plasmodium falciparum confers cellular resistance to antimalarial drugs in yeast cells. Proceedings of the National Academy of Sciences of the United States of America, 1996, Sep-03, Volume: 93, Issue:18 Topics: Alleles; Animals; Antimalarials; ATP-Binding Cassette Transporters; Dose-Response Relationship, Drug; Drug Resistance; Mefloquine; Mice; Phenanthrenes; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinacrine; Quinine	1996
In vitro selection of halofantrine resistance in Plasmodium falciparum is not associated with increased expression of Pgh1. Molecular and biochemical parasitology, 1996, Dec-02, Volume: 83, Issue:1 Topics: Animals; Antimalarials; ATP-Binding Cassette Transporters; Biological Transport; Chloroquine; DNA Fingerprinting; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance, Multiple; Gene Dosage; Gene Expression; Immunoblotting; Mefloquine; Phenanthrenes; Plasmodium falciparum; Protozoan Proteins; Quinine; Selection, Genetic; Sequence Analysis, DNA; Verapamil	1996
X-ray crystal structure of the antimalarial agent (-)-halofantrine hydrochloride supports stereospecificity for cardiotoxicity. Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:4 Topics: Antimalarials; Crystallography, X-Ray; Heart Diseases; Hydrogen Bonding; Molecular Conformation; Phenanthrenes; Quinidine; Quinine; Stereoisomerism	1997
[Malaria in expatriates in Africa. 154 cases. Clinical problems and therapeutic difficulties]. Presse medicale (Paris, France : 1983), 1997, Feb-15, Volume: 26, Issue:4 Topics: Adult; Antimalarials; Female; France; Gabon; Humans; Malaria, Falciparum; Male; Military Personnel; Phenanthrenes; Quinine; Transients and Migrants	1997
Recrudescence of Plasmodium falciparum malaria contracted in Lombok, Indonesia after quinine/doxycycline and mefloquine: case report. The New Zealand medical journal, 1997, Jul-11, Volume: 110, Issue:1047 Topics: Adult; Animals; Anti-Bacterial Agents; Antimalarials; Doxycycline; Drug Combinations; Drug Resistance, Multiple; Humans; Indonesia; Malaria, Cerebral; Malaria, Falciparum; Male; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Recurrence	1997
In vitro activity of artemether against African isolates (Senegal) of Plasmodium falciparum in comparison with standard antimalarial drugs. The American journal of tropical medicine and hygiene, 1998, Volume: 58, Issue:3 Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance; Erythrocytes; Humans; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Senegal; Sesquiterpenes	1998
Follow-up of the susceptibility of Plasmodium falciparum to antimalarials in Gabon. The American journal of tropical medicine and hygiene, 1998, Volume: 58, Issue:5 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Dose-Response Relationship, Drug; Drug Resistance; Follow-Up Studies; Gabon; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Sesquiterpenes; Sulfadoxine	1998
In vitro sensitivity of Plasmodium falciparum to halofantrine compared with chloroquine, quinine and mefloquine in the region of Bobo-Dioulasso, Burkina Faso (West Africa). Tropical medicine & international health : TM & IH, 1998, Volume: 3, Issue:5 Topics: Animals; Antimalarials; Burkina Faso; Chloroquine; Drug Resistance; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine	1998
Recurrence of blackwater fever: triggering of relapses by different antimalarials. Tropical medicine & international health : TM & IH, 1998, Volume: 3, Issue:8 Topics: Adult; Aged; Antimalarials; Belgium; Blackwater Fever; Diagnosis, Differential; Female; Humans; Male; Mefloquine; Middle Aged; Phenanthrenes; Quinine; Recurrence	1998
[Treatment of malaria: let us be sensible!]. Presse medicale (Paris, France : 1983), 1998, Jan-24, Volume: 27, Issue:3 Topics: Antimalarials; Humans; Malaria, Falciparum; Phenanthrenes; Quinine; Severity of Illness Index	1998
In vitro susceptibility of Gabonese wild isolates of Plasmodium falciparum to artemether, and comparison with chloroquine, quinine, halofantrine and amodiaquine. Parasitology, 1998, Volume: 117 ( Pt 6) Topics: Adolescent; Amodiaquine; Animals; Antimalarials; Artemether; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Resistance, Microbial; Gabon; Humans; Infant; Malaria, Falciparum; Phenanthrenes; Plasmodium falciparum; Quinine; Sesquiterpenes	1998
In vitro susceptibility of African isolates of Plasmodium falciparum from Gabon to pyronaridine. The American journal of tropical medicine and hygiene, 1999, Volume: 60, Issue:1 Topics: Adolescent; Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Gabon; Humans; Infant; Malaria, Falciparum; Naphthyridines; Phenanthrenes; Plasmodium falciparum; Quinine	1999
[Malaria--state of the art. 2: Therapy and prevention of malaria]. Fortschritte der Medizin, 1999, Jan-20, Volume: 117, Issue:1-2 Topics: Adolescent; Adult; Animals; Antimalarials; Child; Child, Preschool; Emergencies; Humans; Infant; Malaria; Phenanthrenes; Plasmodium falciparum; Quinine; Travel; Tropical Climate	1999
[The proper use of antimalarial drugs currently available]. Bulletin de la Societe de pathologie exotique (1990), 1998, Volume: 91, Issue:5 Pt 1-2 Topics: Animals; Antimalarials; Chemoprevention; Chloroquine; Contraindications; Drug Combinations; Drug Resistance; Endemic Diseases; Humans; Malaria; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Phenanthrenes; Plasmodium; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Proguanil; Pyrimethamine; Quinine; Sulfadoxine; Travel	1998
[Pulmonary manifestations associated with malaria]. Revue de pneumologie clinique, 1998, Volume: 54, Issue:6 Topics: Adult; Anti-Bacterial Agents; Antimalarials; Bronchitis; Child; Chloroquine; Female; Humans; Infant, Newborn; Lung Diseases; Malaria, Falciparum; Male; Mefloquine; Oxygen Inhalation Therapy; Phenanthrenes; Pleurisy; Pregnancy; Pregnancy Complications, Parasitic; Pulmonary Edema; Quinidine; Quinine; Respiratory Distress Syndrome, Newborn; Travel	1998
Risk factors for gametocyte carriage in uncomplicated falciparum malaria. The American journal of tropical medicine and hygiene, 1999, Volume: 60, Issue:6 Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Carrier State; Child; Child, Preschool; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Multivariate Analysis; Parasitemia; Phenanthrenes; Plasmodium falciparum; Prospective Studies; Quinine; Regression Analysis; Risk Factors; Seroepidemiologic Studies; Sesquiterpenes; Thailand	1999
Phenotypic and genotypic characteristics of recently adapted isolates of Plasmodium falciparum from Thailand. The American journal of tropical medicine and hygiene, 1999, Volume: 60, Issue:3 Topics: Animals; Antimalarials; Blotting, Western; Chloroquine; DNA Fingerprinting; DNA, Protozoan; Drug Resistance; Electrophoresis, Agar Gel; Gene Dosage; Genotype; Humans; Malaria, Falciparum; Mefloquine; Penfluridol; Phenanthrenes; Phenotype; Plasmodium falciparum; Polymerase Chain Reaction; Quinine; Thailand; Verapamil	1999
[Health assessments of a military company stationed on the Maroni River in French Guiana]. Medecine tropicale : revue du Corps de sante colonial, 1999, Volume: 59, Issue:1 Topics: Acclimatization; Animals; Anti-Bacterial Agents; Antimalarials; Chloroquine; Condoms; Crotalid Venoms; Crotalus; Dermatomycoses; Doxycycline; France; French Guiana; Health Education; HIV Infections; Humans; Leishmaniasis, Cutaneous; Malaria, Falciparum; Military Personnel; Phenanthrenes; Quinine; Risk Factors; Sexual Abstinence; Snake Bites; Staphylococcal Skin Infections; Tropical Medicine	1999
The microculture tetrazolium assay (MTA): another colorimetric method of testing Plasmodium falciparum chemosensitivity. Annals of tropical medicine and parasitology, 1999, Volume: 93, Issue:1 Topics: Animals; Antimalarials; Chloroquine; Colorimetry; Dose-Response Relationship, Drug; Drug Resistance; L-Lactate Dehydrogenase; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Tetrazolium Salts	1999
Inoculum effect leads to overestimation of in vitro resistance for artemisinin derivatives and standard antimalarials: a Gambian field study. Parasitology, 1999, Volume: 119 ( Pt 5) Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Gambia; Hematocrit; Humans; Malaria, Falciparum; Mefloquine; Parasitemia; Phenanthrenes; Plasmodium falciparum; Quinine; Scintillation Counting; Sensitivity and Specificity; Sesquiterpenes	1999
Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum. Nature, 2000, Feb-24, Volume: 403, Issue:6772 Topics: Amino Acid Substitution; Animals; Antimalarials; Artemisinins; ATP-Binding Cassette Transporters; Chloroquine; Cloning, Molecular; Drug Resistance; Mefloquine; Mutation; Phenanthrenes; Plasmodium falciparum; Protozoan Proteins; Quinine; Sesquiterpenes; Verapamil	2000
Cytoadherence characteristics of Plasmodium falciparum isolates in Thailand using an in vitro human lung endothelial cells model. The American journal of tropical medicine and hygiene, 2000, Volume: 62, Issue:1 Topics: Adolescent; Adult; Animals; Antibodies, Monoclonal; Antimalarials; Binding, Competitive; Cell Adhesion; Cells, Cultured; Chondroitin Sulfates; Endothelium; Female; Humans; Intercellular Adhesion Molecule-1; Lung; Malaria, Falciparum; Male; Middle Aged; Parasitemia; Phenanthrenes; Plasmodium falciparum; Quinine; Rosette Formation; Thailand	2000
In vitro susceptibility of Plasmodium falciparum to four antimalarial drugs in the Central Province of Papua New Guinea. Papua and New Guinea medical journal, 1998, Volume: 41, Issue:2 Topics: Animals; Antimalarials; Chloroquine; Drug Resistance, Microbial; Humans; Mefloquine; Microbial Sensitivity Tests; Papua New Guinea; Phenanthrenes; Plasmodium falciparum; Quinine	1998
Apparent drug failure following artesunate treatment of Plasmodium falciparum malaria in Freetown, Sierra Leone: four case reports. Annals of tropical medicine and parasitology, 2001, Volume: 95, Issue:5 Topics: Adult; Antimalarials; Artemisinins; Artesunate; Child; Drug Administration Schedule; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Phenanthrenes; Quinine; Sesquiterpenes; Sierra Leone; Treatment Failure	2001
[A collective malarial infestation during a humanitarian mission in west Africa]. Bulletin de la Societe de pathologie exotique (1990), 2002, Volume: 95, Issue:2 Topics: Adult; Altruism; Animals; Antimalarials; Body Weight; Chemoprevention; Chloroquine; Drug Resistance; Humans; Malaria, Falciparum; Male; Mali; Mauritania; Middle Aged; Morocco; Phenanthrenes; Plasmodium falciparum; Proguanil; Quinine; Travel	2002
[Blackwater fever]. Presse medicale (Paris, France : 1983), 2002, Sep-07, Volume: 31, Issue:28 Topics: Adolescent; Adult; Aged; Antimalarials; Atovaquone; Blackwater Fever; Critical Care; Diagnosis, Differential; Drug Combinations; Humans; Mefloquine; Middle Aged; Naphthoquinones; Phenanthrenes; Prognosis; Proguanil; Pyrimethamine; Quinine; Sulfadoxine	2002
The clinical spectrum of severe imported falciparum malaria in the intensive care unit: report of 188 cases in adults. American journal of respiratory and critical care medicine, 2003, Mar-01, Volume: 167, Issue:5 Topics: Adolescent; Adult; Aged; Antimalarials; Community-Acquired Infections; Comorbidity; Cross Infection; Data Interpretation, Statistical; Exchange Transfusion, Whole Blood; Female; France; Glasgow Coma Scale; Humans; Injections, Intravenous; Intensive Care Units; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Phenanthrenes; Quinine; Retrospective Studies; Travel; World Health Organization	2003
In vitro activity of chloroquine, quinine, mefloquine and halofantrine against Gabonese isolates of Plasmodium falciparum. Tropical medicine & international health : TM & IH, 2003, Volume: 8, Issue:1 Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Gabon; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Mefloquine; Parasitic Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Quinine	2003
In-vitro sensitivity of Plasmodium falciparum to chloroquine, halofantrine, mefloquine and quinine in Madagascar. East African medical journal, 2002, Volume: 79, Issue:5 Topics: Animals; Antimalarials; Chloroquine; Drug Evaluation, Preclinical; Drug Resistance; Hospitals, Public; Hospitals, Urban; Humans; Madagascar; Malaria, Falciparum; Mefloquine; Microbial Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Quinine; Rural Health	2002
Defective DNA repair as a potential mechanism for the rapid development of drug resistance in Plasmodium falciparum. Biochemistry, 2004, May-04, Volume: 43, Issue:17 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; DNA Damage; DNA Repair; Drug Resistance; Drug Resistance, Multiple; Humans; Malaria, Falciparum; Mefloquine; Parasitic Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Pyrimethamine; Quinine; Sesquiterpenes; Sulfanilamide; Sulfanilamides; Ultraviolet Rays	2004
pfmdr1 mutations contribute to quinine resistance and enhance mefloquine and artemisinin sensitivity in Plasmodium falciparum. Molecular microbiology, 2005, Volume: 57, Issue:4 Topics: Alleles; Animals; Antimalarials; Artemisinins; Asparagine; Aspartic Acid; ATP-Binding Cassette Transporters; Drug Resistance; Mefloquine; Phenanthrenes; Plasmodium falciparum; Point Mutation; Protozoan Proteins; Quinine; Sesquiterpenes	2005
Decreasing pfmdr1 copy number in plasmodium falciparum malaria heightens susceptibility to mefloquine, lumefantrine, halofantrine, quinine, and artemisinin. The Journal of infectious diseases, 2006, Aug-15, Volume: 194, Issue:4 Topics: Animals; Antimalarials; Artemisinins; ATP-Binding Cassette Transporters; DNA, Protozoan; Drug Resistance, Multiple; Ethanolamines; Fluorenes; Genes, MDR; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Mefloquine; Parasitic Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Polymerase Chain Reaction; Protozoan Proteins; Quinine; Sesquiterpenes	2006
The in-vitro susceptibilities of Ghanaian Plasmodium falciparum to antimalarial drugs. Annals of tropical medicine and parasitology, 2007, Volume: 101, Issue:5 Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Chloroquine; Drug Resistance; Ghana; Humans; Infant; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Sesquiterpenes	2007
In vitro activities of quinine and other antimalarials and pfnhe polymorphisms in Plasmodium isolates from Kenya. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:8 Topics: Amino Acid Sequence; Animals; Antimalarials; Drug Resistance; Humans; Kenya; Mefloquine; Membrane Transport Proteins; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinine; Sequence Analysis, DNA; Sodium-Hydrogen Exchangers	2010
Effects of anti-malarial drugs on the electrocardiographic QT interval modelled in the isolated perfused guinea pig heart system. Malaria journal, 2010, Nov-10, Volume: 9 Topics: Animals; Antimalarials; Arrhythmias, Cardiac; Guinea Pigs; Heart; Heart Conduction System; Mefloquine; Phenanthrenes; Quinidine; Quinine; Time Factors	2010
In vitro susceptibility of Plasmodium falciparum to monodesethylamodiaquine, quinine, mefloquine and halofantrine in Abidjan (Côte d'Ivoire). African health sciences, 2010, Volume: 10, Issue:2 Topics: Adolescent; Adult; Amodiaquine; Antimalarials; Child; Child, Preschool; Cote d'Ivoire; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Microbial Sensitivity Tests; Middle Aged; Phenanthrenes; Plasmodium falciparum; Quinine; Young Adult	2010
Discordant temporal evolution of Pfcrt and Pfmdr1 genotypes and Plasmodium falciparum in vitro drug susceptibility to 4-aminoquinolines after drug policy change in French Guiana. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:3 Topics: Aminoquinolines; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance; Ethanolamines; Evolution, Molecular; Fluorenes; French Guiana; Gene Dosage; Haplotypes; Humans; Inhibitory Concentration 50; Longitudinal Studies; Malaria, Falciparum; Mefloquine; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Practice Guidelines as Topic; Protozoan Proteins; Quinine	2012
Effect of ketoconazole, a cytochrome P450 inhibitor, on the efficacy of quinine and halofantrine against Schistosoma mansoni in mice. The Korean journal of parasitology, 2013, Volume: 51, Issue:2 Topics: Animals; Anthelmintics; Disease Models, Animal; Drug Synergism; Female; Humans; Intestines; Ketoconazole; Liver; Male; Mice; Parasite Load; Phenanthrenes; Quinine; Schistosoma mansoni; Schistosomiasis mansoni; Treatment Outcome	2013