halofantrine has been researched along with pyrimethamine in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.57) | 18.7374 |
| 1990's | 17 (60.71) | 18.2507 |
| 2000's | 8 (28.57) | 29.6817 |
| 2010's | 2 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jomaa, H; Mitsch, A; Schlitzer, M; Wiesner, J; Wissner, P | 1 |
| Masseno, V; Muriithi, S; Nzila, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Chutmongkonkul, M; Maier, WA; Seitz, HM | 2 |
| Bourdeau, EF; Childs, GE; Milhous, WK; Pang, L; Wimonwattratee, T | 1 |
| Childs, GE; Pooyindee, N; Wimonwattrawatee, T | 1 |
| Duong, TH; Igwangou, P; Kombila, M; Ngou-Milama, E; Ozouaki, P | 1 |
| Edwards, G; Ward, SA; Winstanley, PA | 1 |
| Basco, LK; Le Bras, J | 1 |
| Basco, LK; Le Bras, J; Ramiliarisoa, O | 1 |
| Marsh, K; Watkins, WM; Woodrow, C | 1 |
| Mharakurwa, S | 1 |
| Basco, LK; de Pecoulas, PE; Le Bras, J; Wilson, CM | 1 |
| Chunge, C; Luta, M; Mbori-Ngacha, DA; Muga, RO; Oloo, AJ; Onyango, FE | 1 |
| Anabwani, GM; Esamai, FO; Menya, DA | 1 |
| Ezedinachi, E | 1 |
| Hartwell, LH; Sibley, CH; Vasquez, B; Wooden, JM | 1 |
| Falade, CO; Fehintola, FA; Kyle, DE; Makler, MT; Milhous, WK; Oduola, AM; Ogundahunsi, OA; Omitowoju, GO; Piper, RC; Schuster, BG; Sowunmi, A | 1 |
| Bourgeade, A; Delmont, J | 1 |
| Hombhanje, FW | 1 |
| Makonnen, E; Mengesha, T | 1 |
| Adamu, A; Agbonlahor, DE; Dalyop, P; Elesha, SO; Fagbenro-Beyioku, AF; Ogunbanwo, JA | 1 |
| Bedos, JP; Bruneel, F; Danis, M; Gachot, B; Regnier, B; Vachon, F; Wolff, M | 1 |
| Nakajima, Y | 1 |
| Hayton, K; Su, XZ | 1 |
| Brown, ML; Geyer, JA; Terrell, JC; Trotta, RF | 1 |
| Al-Farsi, HM; Al-Hashami, ZS; Al-Qahtani, A; Al-Sheikh, AA; Babiker, HA; Bin Dajem, SM | 1 |
4 review(s) available for halofantrine and pyrimethamine
| Article | Year |
|---|---|
Clinical pharmacokinetics in the treatment of tropical diseases. Some applications and limitations.
Topics: Chloroquine; Diethylcarbamazine; Drug Resistance; Echinococcosis; Filariasis; Humans; Malaria; Mefloquine; Pharmacokinetics; Phenanthrenes; Pyrimethamine; Quinine; Sulfadoxine; Tropical Medicine | 1994 |
Comparative efficacy and safety of chloroquine and alternative antimalarial drugs: a meta-analysis from six African countries.
Topics: Africa, Eastern; Africa, Western; Amodiaquine; Antimalarials; Chloroquine; Drug Combinations; Drug Costs; Humans; Malaria; Mefloquine; Patient Selection; Phenanthrenes; Pyrimethamine; Quinine; Safety; Sulfadoxine; Treatment Outcome | 1999 |
[Antiprotozoal drugs].
Topics: Animals; Antiprotozoal Agents; Drug Combinations; Emetine; Humans; Mefloquine; Metronidazole; Phenanthrenes; Primaquine; Protozoan Infections; Pyrimethamine; Quinine; Sulfadoxine; Tinidazole | 2003 |
Genetic and biochemical aspects of drug resistance in malaria parasites.
Topics: Animals; Antimalarials; Chloroquine; Dihydropteroate Synthase; Drug Resistance; Drug Resistance, Multiple; Humans; Linkage Disequilibrium; Malaria; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Membrane Proteins; Membrane Transport Proteins; Mutation; Phenanthrenes; Plasmodium falciparum; Plasmodium vivax; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2004 |
4 trial(s) available for halofantrine and pyrimethamine
| Article | Year |
|---|---|
Efficacy of halofantrine in the treatment of uncomplicated falciparum malaria.
Topics: Adolescent; Adult; Antimalarials; Child; Child, Preschool; Double-Blind Method; Drug Combinations; Drug Resistance; Female; Humans; Infant; Malaria, Falciparum; Male; Phenanthrenes; Pyrimethamine; Sulfalene; Survival Analysis; Time Factors; Treatment Outcome | 1995 |
A randomised controlled trial to assess the relative efficacy of chloroquine, amodiaquine, halofantrine and Fansidar in the treatment of uncomplicated malaria in children.
Topics: Amodiaquine; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Follow-Up Studies; Humans; Malaria, Falciparum; Male; Phenanthrenes; Pyrimethamine; Sulfadoxine; Treatment Outcome | 1996 |
In vivo efficacy of chloroquine, halofantrine, pyrimethamine-sulfadoxine and qinghaosu (artesunate) in the treatment of malaria in Calabar, Nigeria.
Topics: Adolescent; Antimalarials; Artemisinins; Artesunate; Child; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Nigeria; Phenanthrenes; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Time Factors; Urban Health | 1996 |
Effect of a single oral dose of Fansidar on the pharmacokinetics of halofantrine in healthy volunteers: a preliminary report.
Topics: Adult; Antimalarials; Cross-Over Studies; Drug Combinations; Drug Interactions; Humans; Male; Phenanthrenes; Pyrimethamine; Sulfadoxine | 2000 |
20 other study(ies) available for halofantrine and pyrimethamine
| Article | Year |
|---|---|
Structure-activity relationships of novel anti-malarial agents. Part 2: cinnamic acid derivatives.
Topics: Animals; Antimalarials; Cinnamates; Combinatorial Chemistry Techniques; Inhibitory Concentration 50; Microbial Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship | 2001 |
In vitro chemosensitization of Plasmodium falciparum to antimalarials by verapamil and probenecid.
Topics: Adjuvants, Pharmaceutic; Animals; Antimalarials; Parasitic Sensitivity Tests; Plasmodium falciparum; Probenecid; Verapamil | 2009 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Plasmodium falciparum: effect of chloroquine, halofantrine and pyrimethamine on the infectivity of gametocytes for Anopheles stephensi mosquitoes.
Topics: Animals; Anopheles; Antimalarials; Chloroquine; Insect Vectors; Phenanthrenes; Plasmodium falciparum; Pyrimethamine | 1992 |
A new model for testing gametocytocidal effects of some antimalarial drugs on Plasmodium falciparum in vitro.
Topics: Animals; Anopheles; Antimalarials; Chloroquine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; In Vitro Techniques; Models, Biological; Phenanthrenes; Plasmodium falciparum; Pyrimethamine; Quinine | 1992 |
In vitro and clinical correlates of mefloquine resistance of Plasmodium falciparum in eastern Thailand.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Butylated Hydroxytoluene; Chloroquine; Drug Resistance; Drugs, Chinese Herbal; Mefloquine; Molecular Structure; Phenanthrenes; Plasmodium falciparum; Pyridines; Pyrimethamine; Quinine; Sesquiterpenes; Thailand | 1991 |
Evaluation of an in vitro assay system for drug susceptibility of field isolates of Plasmodium falciparum from southern Thailand.
Topics: Amodiaquine; Animals; Antimalarials; Butylated Hydroxytoluene; Chloroquine; Humans; Mefloquine; Parasitology; Phenanthrenes; Plasmodium falciparum; Pyridines; Pyrimethamine; Quinine; Quinolines; Thailand; Triazines | 1988 |
[Variation of cholostase enzymes (5'-nucleotidase and alkaline phosphatase) during a specific treatment for malaria in the Gabonese child].
Topics: 5'-Nucleotidase; Alkaline Phosphatase; Antimalarials; Child; Child, Preschool; Drug Combinations; Gabon; Humans; Infant; Malaria; Mefloquine; Phenanthrenes; Pyrimethamine; Reference Values; Sulfadoxine | 1995 |
In vitro susceptibility of Cambodian isolates of Plasmodium falciparum to halofantrine, pyronaridine and artemisinin derivatives.
Topics: Adult; Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Humans; In Vitro Techniques; Mefloquine; Naphthyridines; Phenanthrenes; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine; Sesquiterpenes; Triazines | 1994 |
In vitro activity of pyrimethamine, cycloguanil, and other antimalarial drugs against African isolates and clones of Plasmodium falciparum.
Topics: Africa; Animals; Antimalarials; Chloroquine; Drug Resistance; Humans; Mefloquine; Phenanthrenes; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine; Triazines | 1994 |
Falciparum malaria: differential effects of antimalarial drugs on ex vivo parasite viability during the critical early phase of therapy.
Topics: Animals; Antimalarials; Drug Combinations; Drug Therapy, Combination; Humans; Malaria, Falciparum; Phenanthrenes; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine; Time Factors | 1993 |
A case of dual chloroquine and halofantrine treatment failure in Zimbabwe.
Topics: Adult; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Male; Phenanthrenes; Pyrimethamine; Sulfadoxine; Zimbabwe | 1995 |
Plasmodium falciparum: molecular characterization of multidrug-resistant Cambodian isolates.
Topics: Alleles; Animals; Antimalarials; Blotting, Southern; Cambodia; Chloroquine; Codon; DNA Fingerprinting; DNA, Protozoan; Drug Resistance, Multiple; Folic Acid Antagonists; Genes, Protozoan; Genetic Variation; Humans; Mefloquine; Phenanthrenes; Plasmodium falciparum; Polymorphism, Genetic; Proguanil; Pyrimethamine; Triazines | 1996 |
Analysis in yeast of antimalaria drugs that target the dihydrofolate reductase of Plasmodium falciparum.
Topics: Animals; Antimalarials; Chloroquine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Resistance; Folic Acid Antagonists; Genes, Protozoan; Phenanthrenes; Plasmodium falciparum; Pyrimethamine; Recombinant Proteins; Saccharomyces cerevisiae; Tetrahydrofolate Dehydrogenase; Triazines | 1997 |
Plasmodium falciparum: evaluation of lactate dehydrogenase in monitoring therapeutic responses to standard antimalarial drugs in Nigeria.
Topics: Adolescent; Adult; Antimalarials; Artemether; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Humans; Infant; L-Lactate Dehydrogenase; Malaria, Falciparum; Male; Monitoring, Physiologic; Nigeria; Phenanthrenes; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Outcome | 1997 |
[The proper use of antimalarial drugs currently available].
Topics: Animals; Antimalarials; Chemoprevention; Chloroquine; Contraindications; Drug Combinations; Drug Resistance; Endemic Diseases; Humans; Malaria; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Phenanthrenes; Plasmodium; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Proguanil; Pyrimethamine; Quinine; Sulfadoxine; Travel | 1998 |
Effects of anti-protozoal drugs and histopathological studies on trypanosome species.
Topics: Animals; Chloroquine; Female; Humans; Male; Metronidazole; Parasitic Sensitivity Tests; Phenanthrenes; Pyrimethamine; Rats; Trypanosoma; Trypanosomiasis | 2001 |
[Blackwater fever].
Topics: Adolescent; Adult; Aged; Antimalarials; Atovaquone; Blackwater Fever; Critical Care; Diagnosis, Differential; Drug Combinations; Humans; Mefloquine; Middle Aged; Naphthoquinones; Phenanthrenes; Prognosis; Proguanil; Pyrimethamine; Quinine; Sulfadoxine | 2002 |
Defective DNA repair as a potential mechanism for the rapid development of drug resistance in Plasmodium falciparum.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; DNA Damage; DNA Repair; Drug Resistance; Drug Resistance, Multiple; Humans; Malaria, Falciparum; Mefloquine; Parasitic Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Pyrimethamine; Quinine; Sesquiterpenes; Sulfanilamide; Sulfanilamides; Ultraviolet Rays | 2004 |
Distribution of drug resistance genotypes in Plasmodium falciparum in an area of limited parasite diversity in Saudi Arabia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Genotype; Humans; Infant; Male; Mefloquine; Membrane Transport Proteins; Middle Aged; Multidrug Resistance-Associated Proteins; Mutation; Phenanthrenes; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Pyrimethamine; Saudi Arabia; Sulfadoxine; Tetrahydrofolate Dehydrogenase; Young Adult | 2012 |