ha 1004 has been researched along with n-(2-(methylamino)ethyl)-5-isoquinolinesulfonamide in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (16.67) | 18.7374 |
| 1990's | 13 (72.22) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gerena, L; Geyer, JA; Keenan, SM; Waters, NC; Welsh, WJ; Woodard, CL | 1 |
| Amano, S; Hanazawa, S; Kitami, H; Kitano, S; Murakami, Y; Ohta, K; Takeshita, A | 1 |
| Citi, S | 1 |
| Kumegawa, M; Oshima, T; Tanabe, T; Yamamoto, S; Yokoyama, C; Yoshimoto, T | 1 |
| Chipkin, SR; Goodman, HM; Tai, LR | 1 |
| Autieri, MV; Coffman, FD; Cohen, S; Fresa, KL; Katz, ME | 1 |
| Berg, KL; Foster, DA; Joseph, C; Qureshi, SA; Spangler, R | 1 |
| Adamo, S; Cavallo, G; Frati, L; Gismondi, A; Paolini, R; Piccoli, M; Procopio, AD; Santoni, A | 1 |
| Cosgrove, JM; Howcroft, TK; Lindquist, RR; Tatum, SM | 1 |
| Evans, DL; Jaso-Friedmann, L; Leary, JH | 1 |
| Walters, JD; Wojcik, MS | 1 |
| Aloyo, VJ | 1 |
| Hanazawa, S; Iwasaka, H; Kawakami, K; Kitano, S; Murakami, Y; Naganuma, K; Watanabe, A | 1 |
| Burighel, P; Citi, S; Denisenko, N | 1 |
| Berns, CM; Corry, PM; Erdos, G; Lee, YJ | 1 |
| Beezhold, DH; Chang, ZL; Personius, CD; Shen, ZL | 1 |
| Adler, MR; Botsford, SA; Gronau, RT; Light, DB; Ter Beest, JK | 1 |
| Johnson, SW; Shen, KZ | 1 |
18 other study(ies) available for ha 1004 and n-(2-(methylamino)ethyl)-5-isoquinolinesulfonamide
| Article | Year |
|---|---|
Evaluation of broad spectrum protein kinase inhibitors to probe the architecture of the malarial cyclin dependent protein kinase Pfmrk.
Topics: Animals; Binding Sites; Crystallography, X-Ray; Cyclic AMP-Dependent Protein Kinases; Cyclin-Dependent Kinases; Drug Evaluation, Preclinical; Enzyme Inhibitors; Inhibitory Concentration 50; Ligands; Malaria; Molecular Conformation; Naphthalenes; Plasmodium falciparum; Sulfonamides | 2007 |
Porphyromonas gingivalis fimbriae induce expression of the neutrophil chemotactic factor KC gene of mouse peritoneal macrophages: role of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blotting, Northern; Bucladesine; Chemotaxis, Leukocyte; Colforsin; Dose-Response Relationship, Drug; Fimbriae, Bacterial; Gene Expression Regulation, Bacterial; Interleukin-8; Isoquinolines; Macrophages; Mice; Mice, Inbred BALB C; Neutrophils; Piperazines; Porphyromonas gingivalis; Protein Kinase C; RNA; Sulfonamides; Tetradecanoylphorbol Acetate | 1992 |
Protein kinase inhibitors prevent junction dissociation induced by low extracellular calcium in MDCK epithelial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Azepines; Calcium; Cell Communication; Cell Line; Dogs; Egtazic Acid; Epithelium; Fluorescent Antibody Technique; Intercellular Junctions; Isoquinolines; Kidney; Kinetics; Naphthalenes; Piperazines; Protein Kinase Inhibitors; Staurosporine; Sulfonamides | 1992 |
cAMP-dependent induction of fatty acid cyclooxygenase mRNA in mouse osteoblastic cells (MC3T3-E1).
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blotting, Northern; Blotting, Western; Cell Line; Cyclic AMP; Cycloheximide; Dactinomycin; Dinoprostone; Enzyme Induction; Epinephrine; Gene Expression; Isoquinolines; Mice; Osteoblasts; Piperazines; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Sulfonamides | 1991 |
The isoquinoline sulfonamide inhibitors of protein phosphorylation, H-7, H-8, and HA-1004, also inhibit RNA synthesis: studies on responses of adipose tissue to growth hormone.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adipose Tissue; Animals; Growth Hormone; Insulin; Isoquinolines; Lipolysis; Male; Phosphorylation; Piperazines; Protein Kinase C; Proteins; Rats; Rats, Inbred Strains; RNA; Sulfonamides | 1990 |
Induction of a cytoplasmic activator of DNA synthesis in lymphocytes is mediated through a membrane-associated protein kinase.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaline Phosphatase; Amino Acid Sequence; Aprotinin; Cell Nucleus; Gene Expression Regulation, Enzymologic; Humans; Isoquinolines; Leukemia, Lymphoid; Lymphocytes; Membrane Proteins; Membranes; Peptides; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Protein Precursors; Serine Endopeptidases; Signal Transduction; Subcellular Fractions; Sulfonamides | 1990 |
Evidence that v-src and v-fps gene products use a protein kinase C-mediated pathway to induce expression of a transformation-related gene.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Calcium Channel Blockers; Cell Transformation, Neoplastic; Chick Embryo; Gene Products, gag; Isoquinolines; Kinetics; Oncogene Protein pp60(v-src); Oncogenes; Phorbol Esters; Phosphorylation; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Retroviridae Proteins; RNA, Messenger; Signal Transduction; Sulfonamides; Transcription, Genetic | 1989 |
Effects of protein kinase C (PK-C) activators and inhibitors on human large granular lymphocytes (LGL): role of PK-C on natural killer (NK) activity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Diglycerides; Enzyme Activation; Ethers; Humans; Immunity, Innate; Ionomycin; Isoquinolines; Killer Cells, Natural; Molecular Weight; Phosphoproteins; Piperazines; Protein Kinase C; Sulfonamides; Tetradecanoylphorbol Acetate | 1989 |
Protein kinase C (PKC) inhibitors inhibit primary (1-0) but not secondary (1-1) or cloned cytotoxic T lymphocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Clone Cells; Cytotoxicity, Immunologic; Isoquinolines; Mice; Piperazines; Protein Kinase C; Sulfonamides; T-Lymphocytes, Cytotoxic | 1988 |
Pathways of signaling in nonspecific cytotoxic cells: effects of protein kinase and phosphatase inhibitors and evidence for membrane tyrosine phosphorylation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Catfishes; Cell Membrane; Cytotoxicity, Immunologic; Female; Immunity, Cellular; Isoquinolines; Male; Phosphoprotein Phosphatases; Phosphotyrosine; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Signal Transduction; Sulfonamides; Tyrosine | 1994 |
Polyamine transport in human promyelocytic leukemia cells and polymorphonuclear leukocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Biological Transport; Cell Line; Genistein; Gramicidin; Humans; In Vitro Techniques; Ionomycin; Isoflavones; Isoquinolines; Kinetics; Leukemia, Promyelocytic, Acute; Neutrophils; Piperazines; Protein Kinase Inhibitors; Putrescine; Spermidine; Spermine; Sulfonamides; Temperature; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Modulation of mu opioid binding by protein kinase inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Analgesics; Animals; Binding, Competitive; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; Isoquinolines; Kinetics; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Rabbits; Receptors, Opioid, mu; Sulfonamides; Tritium | 1995 |
Porphyromonas gingivalis fimbriae induce a 68-kilodalton phosphorylated protein in macrophages.
Topics: Alkaloids; Animals; Cell Compartmentation; Chemokine CXCL1; Chemokines; Chemokines, CXC; Chemotaxis, Leukocyte; Cyclic AMP-Dependent Protein Kinases; Cytokines; Cytosol; Fimbriae, Bacterial; Humans; Isoquinolines; Macrophages, Peritoneal; Mice; Monocytes; Phosphoproteins; Porphyromonas gingivalis; Protein Kinase C; Signal Transduction; Staurosporine; Sulfonamides | 1994 |
Different effects of protein kinase inhibitors on the localization of junctional proteins at cell-cell contact sites.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actin Cytoskeleton; Actins; Alkaloids; Animals; Cadherins; Calcium; Cell Line; Cytoskeletal Proteins; Cytoskeleton; Desmoplakins; Dogs; Epithelium; Intercellular Junctions; Isoquinolines; Kidney; Membrane Proteins; Phosphoproteins; Piperazines; Protein Kinase Inhibitors; Staurosporine; Sulfonamides; Zonula Occludens-1 Protein | 1994 |
Effect of isoquinolinesulfonamides on heat shock gene expression during heating at 41 degrees C in human carcinoma cell lines.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Blotting, Northern; Breast Neoplasms; Cyclic AMP-Dependent Protein Kinases; Female; Gene Expression Regulation, Neoplastic; Heat-Shock Proteins; Hot Temperature; Humans; Isoquinolines; Kinetics; Leucine; Male; Piperazines; Prostatic Neoplasms; Protein Kinase C; RNA, Messenger; Sulfonamides; Tumor Cells, Cultured | 1994 |
Fibronectin cell-binding domain triggered transmembrane signal transduction in human monocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Cell Division; Cells, Cultured; Chymotrypsin; Dactinomycin; Fibronectins; Humans; Isoquinolines; Kinetics; L Cells; Lipopolysaccharides; Mice; Monocytes; Peptide Fragments; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Signal Transduction; Sulfonamides; Time Factors; Tumor Necrosis Factor-alpha | 1993 |
Protein kinase C and regulatory volume decrease in mudpuppy red blood cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Benzophenanthridines; Calcium; Cell Size; Enzyme Inhibitors; Erythrocytes; Gramicidin; Hematocrit; Hypotonic Solutions; Indoles; Ion Channel Gating; Ion Transport; Isoquinolines; Maleimides; Models, Biological; Necturus; Osmotic Fragility; Osmotic Pressure; Patch-Clamp Techniques; Phenanthridines; Potassium Channels; Protein Kinase C; Sulfonamides | 1998 |
Group II metabotropic glutamate receptor modulation of excitatory transmission in rat subthalamic nucleus.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenylyl Cyclase Inhibitors; Amino Acids; Amino Acids, Dicarboxylic; Animals; Colforsin; Cyclopropanes; Electric Stimulation; Electrophysiology; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Glycine; Imines; In Vitro Techniques; Isoquinolines; Male; Picrotoxin; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Subthalamic Nucleus; Sulfonamides; Synaptic Transmission; Tetradecanoylphorbol Acetate; Xanthenes | 2003 |