h-d-phe-pip-arg-pna has been researched along with hirudin in 12 studies
| Studies (h-d-phe-pip-arg-pna) | Trials (h-d-phe-pip-arg-pna) | Recent Studies (post-2010) (h-d-phe-pip-arg-pna) | Studies (hirudin) | Trials (hirudin) | Recent Studies (post-2010) (hirudin) |
|---|---|---|---|---|---|
| 95 | 1 | 5 | 21 | 0 | 2 |
| 95 | 1 | 5 | 3,658 | 378 | 995 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (16.67) | 18.7374 |
| 1990's | 8 (66.67) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| De Cristofaro, R; Landolfi, R | 1 |
| Broersma, RJ; Krstenansky, JL; Mao, SJ; Owen, TJ; Payne, MH; Yates, MT | 1 |
| Firkin, BG; Sloan, IG | 1 |
| Kaminski, M; McDonagh, J | 1 |
| Gast, A; Tschopp, TB | 1 |
| Berry, CN; Girardot, C; Lecoffre, C; Lunven, C | 1 |
| Dang, QD; Di Cera, E | 1 |
| Johnstone, MT; LoGerfo, FW; Loza, JP; Ozaki, CK; Phaneuf, MD; Quist, WC | 1 |
| Angliker, H; Duffy, EJ; Le Bonniec, BF; Stone, SR | 1 |
| Francischetti, B; Francischetti, IM; Guimarães, JA; Monteiro, RQ | 1 |
| Betz, A; Le Bonniec, BF; Myles, T; Stone, SR | 1 |
| Hoffmann, JJ; Janssen, WC | 1 |
12 other study(ies) available for h-d-phe-pip-arg-pna and hirudin
| Article | Year |
|---|---|
Allosteric modulation of BPTI interaction with human alpha- and zeta-thrombin.
Topics: Allosteric Regulation; Aprotinin; Binding Sites; Dipeptides; Enzyme Activation; Hirudins; Humans; Kinetics; Peptide Fragments; Protein Binding; Protein C; Recombinant Proteins; Sodium; Thermodynamics; Thrombin; Thrombomodulin | 1999 |
Development of MDL 28,050, a small stable antithrombin agent based on a functional domain of the leech protein, hirudin.
Topics: Amino Acid Sequence; Animals; Antithrombins; Blood Coagulation Tests; Chromogenic Compounds; Dipeptides; Hirudins; Molecular Sequence Data; Oligopeptides; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Thrombin | 1990 |
Effects of EACA on thrombin generation as measured by the chromagen S2238.
Topics: alpha-Macroglobulins; Aminocaproates; Aminocaproic Acid; Chromogenic Compounds; Dipeptides; Enzyme Activation; Hirudins; Humans; Kinetics; Molecular Weight; Thrombin; Time Factors | 1986 |
Inhibited thrombins. Interactions with fibrinogen and fibrin.
Topics: Amino Acid Chloromethyl Ketones; Arginine; Binding Sites; Chromatography, Affinity; Dansyl Compounds; Dipeptides; Fibrin; Fibrinogen; Fluorescent Dyes; Hirudins; Phenylmethylsulfonyl Fluoride; Protein Binding; Pyridoxal Phosphate; Thrombin | 1987 |
Inhibition of extrinsic and intrinsic thrombin generation by a novel synthetic thrombin inhibitor (Ro 46-6240), recombinant hirudin and heparin in human plasma.
Topics: Antithrombins; Binding Sites; Chromogenic Compounds; Dipeptides; Heparin; Hirudins; Humans; Hydrolysis; Kinetics; Naphthalenes; Piperidines; Recombinant Proteins; Thrombin | 1995 |
Effects of the synthetic thrombin inhibitor argatroban on fibrin- or clot-incorporated thrombin: comparison with heparin and recombinant Hirudin.
Topics: Antithrombins; Arginine; Blood Coagulation; Dipeptides; Dose-Response Relationship, Drug; Fibrin; Heparin; Hirudins; Humans; Pipecolic Acids; Recombinant Proteins; Sulfonamides; Thrombin | 1994 |
A simple activity assay for thrombin and hirudin.
Topics: Binding Sites; Chromogenic Compounds; Cloning, Molecular; Dipeptides; Hirudins; Kinetics; Models, Theoretical; Mutagenesis, Site-Directed; Protein Binding; Recombinant Proteins; Sensitivity and Specificity; Spectrophotometry; Thrombin | 1994 |
Covalent linkage of streptokinase to recombinant hirudin: a novel thrombolytic agent with antithrombotic properties.
Topics: Binding Sites; Chromogenic Compounds; Cross-Linking Reagents; Dipeptides; Fibrinolytic Agents; Hirudins; Humans; Oligopeptides; Plasminogen; Protein Binding; Substrate Specificity; Thrombin | 1994 |
Allosteric modulation of the activity of thrombin.
Topics: Allosteric Regulation; Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Chromogenic Compounds; Dipeptides; Enzyme Activation; Glutamic Acid; Glutamine; Hirudins; Kinetics; Mutation; Peptide Fragments; Receptors, Thrombin; Substrate Specificity; Thrombin | 1997 |
Identification of glycyrrhizin as a thrombin inhibitor.
Topics: Animals; Anticoagulants; Antithrombins; Binding Sites; Blood Coagulation; Dipeptides; Fibrinogen; Fluorescence; Glycyrrhetinic Acid; Glycyrrhiza; Glycyrrhizic Acid; Hirudins; Oligosaccharides; Plants, Medicinal; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Sialyl Lewis X Antigen; Thrombin | 1997 |
Electrostatic steering and ionic tethering in the formation of thrombin-hirudin complexes: the role of the thrombin anion-binding exosite-I.
Topics: Amino Acid Substitution; Amino Acids; Anions; Antithrombins; Binding, Competitive; Chromogenic Compounds; Dipeptides; Hirudins; Humans; Hydrolysis; Kinetics; Macromolecular Substances; Protein Binding; Recombinant Proteins; Static Electricity; Thermodynamics; Thrombin | 2001 |
Comparison of three methods for measuring PEG-hirudin in blood.
Topics: Antithrombins; Autoanalysis; Blood Coagulation Tests; Chromogenic Compounds; Costs and Cost Analysis; Dipeptides; Hirudins; Humans; Indicators and Reagents; Point-of-Care Systems; Quality Control; Reference Values; Sensitivity and Specificity; Thrombin | 2001 |