Page last updated: 2024-09-03

gyki 53655 and 6-methyl-2-(phenylethynyl)pyridine

gyki 53655 has been researched along with 6-methyl-2-(phenylethynyl)pyridine in 2 studies

Compound Research Comparison

Studies (gyki 53655)	Trials (gyki 53655)	Recent Studies (post-2010) (gyki 53655)	Studies (6-methyl-2-(phenylethynyl)pyridine)	Trials (6-methyl-2-(phenylethynyl)pyridine)	Recent Studies (post-2010) (6-methyl-2-(phenylethynyl)pyridine)
111	0	22	543	0	185

Protein Interaction Comparison

Protein	Taxonomy	6-methyl-2-(phenylethynyl)pyridine (IC50)
Luciferin 4-monooxygenase	Photinus pyralis (common eastern firefly)	6.2333
Metabotropic glutamate receptor 5	Rattus norvegicus (Norway rat)	0.0129
Metabotropic glutamate receptor 5	Homo sapiens (human)	0.0199
Amine oxidase [flavin-containing] A	Mus musculus (house mouse)	8

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ	1
Adamcio, B; Belozertseva, I; Bespalov, A; Dravolina, O; Zvartau, E	1

Other Studies

2 other study(ies) available for gyki 53655 and 6-methyl-2-(phenylethynyl)pyridine

Article	Year
Identification of potent Yes1 kinase inhibitors using a library screening approach. Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15 Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship	2013
Lowered brain stimulation reward thresholds in rats treated with a combination of caffeine and N-methyl-D-aspartate but not alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate or metabotropic glutamate receptor-5 receptor antagonists. Behavioural pharmacology, 2006, Volume: 17, Issue:4 Topics: Animals; Benzodiazepines; Brain; Caffeine; Central Nervous System Stimulants; Conditioning, Operant; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Piperazines; Pyridines; Quinolones; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptor, Metabotropic Glutamate 5; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Reward; Self Stimulation; Ventral Tegmental Area	2006

Article

Year

Identification of potent Yes1 kinase inhibitors using a library screening approach.

Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013

Lowered brain stimulation reward thresholds in rats treated with a combination of caffeine and N-methyl-D-aspartate but not alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate or metabotropic glutamate receptor-5 receptor antagonists.

Behavioural pharmacology, 2006, Volume: 17, Issue:4

Topics: Animals; Benzodiazepines; Brain; Caffeine; Central Nervous System Stimulants; Conditioning, Operant; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Piperazines; Pyridines; Quinolones; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptor, Metabotropic Glutamate 5; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Reward; Self Stimulation; Ventral Tegmental Area

2006