gyki 52466 and kainic acid

gyki 52466 has been researched along with kainic acid in 59 studies

Research

Studies (59)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	33 (55.93)	18.2507
2000's	20 (33.90)	29.6817
2010's	6 (10.17)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cagnotto, A; Colleoni, S; Diana, V; Grasso, S; Lazzaro, J; Mennini, T; Micale, N; Pellicanò, A; Postorino, G; Zappalà, M	1
Arvin, B; Le Peillet, E; Meldrum, BS; Moncada, C	1
Durand, J; Ouardouz, M	1
Meldrum, BS; Smith, SE	1
Burnett, JP; May, PC; Mayne, NG; Sharp, RL; Snyder, YM	1
Gyevai, A; Mike, A; Osipenko, O; Vizi, ES	1
Gruner, R; Parsons, CG; Rozental, J	1
Fattman, CL; Hoyt, KR; Rajdev, S; Reynolds, IJ	1
Audinat, E; Crépel, F; Renard, A	1
Balázs, R; Hack, N	1
Donevan, SD; Rogawski, MA	2
Donevan, SD; Rogawski, MA; Yamaguchi, S	1
Huettner, JE; Wilding, TJ	1
Croucher, MJ; Patel, DR; Sturt, NJ	1
Lerma, J; Morales, M; Paternain, AV	1
Arvin, B; Chapman, AG; Graham, JL; Lekieffre, D; Meldrum, BS; Moncada, C	1
May, PC; Robison, PM	1
Olney, JW; Price, MT; Yamada, KA; Zorumski, CF	1
De Bernardi, R; Ferro, F; Fontana, G; Gemignani, A; Raiteri, M	1
McCaslin, PP; Oh, S	1
Regan, RF	1
Croucher, MJ; Patel, DR	1
Herrmann, A; Weiser, T; Wienrich, M	1
Chen, SC; Wu, FS	1
Fontana, G; Gemignani, A; Marchese, S; Raiteri, M	1
Ohno-Shosaku, T; Sawada, S; Yamamoto, C	1
Kamiya, H; Ozawa, S	1
Liachenko, S; Melick, JA; Tang, P; Xu, Y	1
Bleuel, Z; Clifford, MM; Ellis, GJ; Humbel, U; Klingelschmidt, A; Messer, J; Mutel, V; Richards, JG; Trube, G	1
Blanco, R; de la Villa, P	1
Gao, XB; Liu, QS; Patrylo, PR; van den Pol, AN	1
Chen, Q; Reiner, A; Surmeier, DJ	1
Kim, P; Price, CJ; Raymond, LA	1
Fincher, A; Frye, GD	1
Kohda, K; Wang, Y; Yuzaki, M	1
Durkin, JP; Gendron, TF; MacLean, S; Mealing, G; Morley, P; Small, DL; Tremblay, R	1
Abrahám, G; Andrási, F; Berzsenyi, P; Csuzdi, E; Hámori, T; Hársing, LG; Horváth, G; Horváth, K; Kapus, G; Király, I; Ling, I; Pallagi, I; Patthy, M; Sólyom, S; Tarnawa, I	1
Caicedo, A; Jafri, MS; Roper, SD	1
Lees, GJ; Leong, W	1
Kristensen, BW; Noraberg, J; Zimmer, J	1
Kelland, EE; Toms, NJ	1
Endo, T; Isa, T	1
Shen, W; Slaughter, MM	1
Frye, GD; Hsiao, SH	1
Camins, A; Canudas, AM; Folch, J; Jiménez, A; Jordà, EG; Pallàs, M; Rimbau, V; Verdaguer, E	1
Boehrer, A; Depaulis, A; Heinrich, C; Kurokawa, K; Matsuda, M; Mitsuya, K; Suzuki, F	1
Bennett, SA; Cheung, EC; Cregan, SP; Ferguson, KL; McIntosh, WC; Melanson-Drapeau, L; Park, DS; Slack, RS; Vanderluit, JL	1
Gudz, TI; Komuro, H; Macklin, WB	1
Blasco-Ibáñez, JM; Crespo, C; Domínguez, MI; Marqués-Marí, AI; Martínez-Guijarro, FJ; Nacher, J	1
Erdélyi, F; Fiszman, ML; Szabó, G; Vicini, S	1
DeSilva, TM; Goldhoff, PE; Kabakov, AY; Rosenberg, PA; Volpe, JJ	1
Fritsch, B; Joelle Donofrio, J; Rogawski, MA; Stott, JJ	1
Bhatt, D; Chung, WY; Cooper, RL; Lee, JY	1
Bhattarai, JP; Han, SK; Kim, CJ; Lee, JC; Park, SA; Park, SJ; Yin, H	1
Borbély, S; Czégé, D; Dobó, E; Mihály, A; Molnár, E; Világi, I	1
Berretta, N; Cecconi, F; Cervelli, M; Cervetto, C; D'Amelio, M; Marcoli, M; Mariottini, P; Maura, G; Mercuri, N; Passalacqua, M; Ragazzoni, M; Venturini, A; Vergani, L; Voci, A	1
Barygin, OI	1
Gray, WP; Pringle, A; Sadek, AR; Seifert, G; Shtaya, A; Steinhäuser, C; Zaben, M	1

Other Studies

59 other study(ies) available for gyki 52466 and kainic acid

Article	Year
Structure-activity study of 2,3-benzodiazepin-4-ones noncompetitive AMPAR antagonists: identification of the 1-(4-amino-3-methylphenyl)-3,5-dihydro-7,8-ethylenedioxy-4H-2,3-benzodiazepin-4-one as neuroprotective agent. Bioorganic & medicinal chemistry, 2008, Mar-01, Volume: 16, Issue:5 Topics: Animals; Benzodiazepines; Benzodiazepinones; Calcium; Cells, Cultured; Hippocampus; Inhibitory Concentration 50; Kainic Acid; Ligands; Mice; Molecular Structure; Neurons; Neuroprotective Agents; Protein Binding; Receptors, AMPA; Structure-Activity Relationship	2008
Non-NMDA antagonists protect against kainate more than AMPA toxicity in the rat hippocampus. Neuroscience letters, 1991, Dec-09, Volume: 133, Issue:2 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Hippocampus; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Neurons; Neurotoxins; Pyramidal Tracts; Quinoxalines; Rats; Rats, Inbred Strains	1991
GYKI 52466 antagonizes glutamate responses but not NMDA and kainate responses in rat abducens motoneurones. Neuroscience letters, 1991, Apr-15, Volume: 125, Issue:1 Topics: Abducens Nerve; Animals; Anti-Anxiety Agents; Benzodiazepines; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamates; Kainic Acid; Male; Motor Neurons; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate	1991
Receptor site specificity for the acute effects of beta-N-methylamino-alanine in mice. European journal of pharmacology, 1990, Oct-02, Volume: 187, Issue:1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Benzodiazepines; Cyanobacteria Toxins; Glutamine; Ibotenic Acid; Injections, Intraventricular; Kainic Acid; Kinetics; Male; Mice; N-Methylaspartate; Organophosphorus Compounds; Piperazines; Receptors, Drug; Receptors, N-Methyl-D-Aspartate	1990
Cyclothiazide potentiates agonist responses at human AMPA/kainate receptors expressed in oocytes. European journal of pharmacology, 1994, Jan-01, Volume: 266, Issue:1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Benzothiadiazines; Cloning, Molecular; Humans; Kainic Acid; Oocytes; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Xenopus laevis	1994
Evidence that GYKI 52466, a novel non-NMDA antagonist enhances the decay of kainate-induced current in cultured chicken cortical neurons. Brain research. Developmental brain research, 1994, Feb-18, Volume: 77, Issue:2 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Cerebral Cortex; Chick Embryo; Electrophysiology; Excitatory Amino Acid Antagonists; Ion Channels; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Neurotoxins; Quinoxalines	1994
Comparative patch clamp studies on the kinetics and selectivity of glutamate receptor antagonism by 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline (NBQX) and 1-(4-amino-phenyl)-4-methyl-7,8-methyl-endioxyl-5H-2,3-benzodiaze pine (GYKI 52466). Neuropharmacology, 1994, Volume: 33, Issue:5 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Cells, Cultured; Excitatory Amino Acid Antagonists; Hippocampus; Kainic Acid; Kinetics; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Receptors, AMPA; Superior Colliculi	1994
Cyclothiazide modulates AMPA receptor-mediated increases in intracellular free Ca2+ and Mg2+ in cultured neurons from rat brain. Journal of neurochemistry, 1995, Volume: 64, Issue:5 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Benzothiadiazines; Calcium; Cells, Cultured; Drug Synergism; Glutamic Acid; Kainic Acid; Magnesium; Neurons; Prosencephalon; Rats; Receptors, AMPA	1995
Evidence for two types of non-NMDA receptors in rat cerebellar Purkinje cells maintained in slice cultures. Neuropharmacology, 1995, Volume: 34, Issue:3 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Cerebellum; Electrophysiology; Kainic Acid; Kinetics; Membrane Potentials; Neurotoxins; Organ Culture Techniques; Patch-Clamp Techniques; Purkinje Cells; Rats; Receptors, N-Methyl-D-Aspartate	1995
Properties of AMPA receptors expressed in rat cerebellar granule cell cultures: Ca2+ influx studies. Journal of neurochemistry, 1995, Volume: 65, Issue:3 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Benzothiadiazines; Calcium; Calcium Radioisotopes; Cell Survival; Cells, Cultured; Cerebellum; Cobalt; Concanavalin A; Excitatory Amino Acids; Kainic Acid; N-Methylaspartate; Quinoxalines; Rats; Receptors, AMPA; Wheat Germ Agglutinins	1995
GYKI 52466, a 2,3-benzodiazepine, is a highly selective, noncompetitive antagonist of AMPA/kainate receptor responses. Neuron, 1993, Volume: 10, Issue:1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Cells, Cultured; Electric Conductivity; Excitatory Amino Acid Antagonists; Hippocampus; Ibotenic Acid; Kainic Acid; Kinetics; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Synapses	1993
Anticonvulsant activity of AMPA/kainate antagonists: comparison of GYKI 52466 and NBOX in maximal electroshock and chemoconvulsant seizure models. Epilepsy research, 1993, Volume: 15, Issue:3 Topics: 4-Aminopyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Binding, Competitive; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Hindlimb; Kainic Acid; Male; Mice; Pentylenetetrazole; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; Seizures	1993
Differential antagonism of alpha-amino-3-hydroxy-5-methyl-4- isoxazolepropionic acid-preferring and kainate-preferring receptors by 2,3-benzodiazepines. Molecular pharmacology, 1995, Volume: 47, Issue:3 Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzothiadiazines; Binding, Competitive; Cerebral Cortex; Concanavalin A; Electrophysiology; Ganglia, Spinal; Kainic Acid; Membrane Potentials; Neurons; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Kainic Acid; Substrate Specificity	1995
Modulation of D-[2,3 3H]aspartate release from rat forebrain slices by non-NMDA receptor agonists and antagonists. Biochemical Society transactions, 1995, Volume: 23, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Animals; Anti-Anxiety Agents; Aspartic Acid; Benzodiazepines; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Kainic Acid; Kinetics; Kynurenic Acid; Male; Prosencephalon; Quinoxalines; Rats; Rats, Wistar; Tritium	1995
Selective antagonism of AMPA receptors unmasks kainate receptor-mediated responses in hippocampal neurons. Neuron, 1995, Volume: 14, Issue:1 Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Cells, Cultured; Electric Conductivity; Hippocampus; Kainic Acid; Neuronal Plasticity; Neurons; Rats; Receptors, AMPA; Receptors, Kainic Acid; Synaptic Transmission	1995
Effect of the non-NMDA receptor antagonist GYKI 52466 on the microdialysate and tissue concentrations of amino acids following transient forebrain ischaemia. Journal of neurochemistry, 1994, Volume: 62, Issue:4 Topics: Amino Acids; Animals; Anti-Anxiety Agents; Aspartic Acid; Benzodiazepines; Cerebral Cortex; Corpus Striatum; Dialysis; Dopamine; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; Ischemic Attack, Transient; Kainic Acid; Male; Neurotoxins; Prosencephalon; Rats; Rats, Wistar; Receptors, Neurotransmitter	1994
GYKI 52466 protects against non-NMDA receptor-mediated excitotoxicity in primary rat hippocampal cultures. Neuroscience letters, 1993, Apr-02, Volume: 152, Issue:1-2 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anti-Anxiety Agents; Benzodiazepines; Cells, Cultured; Dose-Response Relationship, Drug; Hippocampus; Kainic Acid; Neurotoxins; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Kainic Acid	1993
A benzodiazepine recognition site associated with the non-NMDA glutamate receptor. Neuron, 1993, Volume: 10, Issue:1 Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzothiadiazines; Binding Sites; Binding, Competitive; Cells, Cultured; Chick Embryo; Electric Conductivity; Excitatory Amino Acid Antagonists; Hippocampus; Kainic Acid; Nerve Degeneration; Neurons; Quisqualic Acid; Rats; Receptors, Glutamate; Retina	1993
Characterization of the glutamate receptors mediating release of somatostatin from cultured hippocampal neurons. Journal of neurochemistry, 1996, Volume: 66, Issue:1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Calcium; Cells, Cultured; Cycloleucine; Dizocilpine Maleate; Drug Synergism; Glutamic Acid; Hippocampus; Kainic Acid; N-Methylaspartate; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Somatostatin; Tetrodotoxin	1996
Kainate produces concentration-dependent elevation of glutamate release but not cGMP levels in cultured neuron. General pharmacology, 1996, Volume: 27, Issue:1 Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Kainic Acid; N-Methylaspartate; Neurons; Neurotoxins; Piperazines; Quinoxalines	1996
The vulnerability of spinal cord neurons to excitotoxic injury: comparison with cortical neurons. Neuroscience letters, 1996, Jul-26, Volume: 213, Issue:1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Cerebral Cortex; Cobalt; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Mice; N-Methylaspartate; Neurons; Neurotoxins; Spinal Cord; Staining and Labeling; Time Factors	1996
A role for presynaptic AMPA receptors in the enhancement of neuronal glutamate release by kainic acid. Biochemical Society transactions, 1996, Volume: 24, Issue:3 Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Kainic Acid; Neurons; Prosencephalon; Quinoxalines; Rats; Receptors, AMPA; Receptors, Presynaptic	1996
Interactions of the dye Evans Blue and GYKI 52466, a 2,3-benzodiazepine, with (S)- alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors in cultured rat cortical neurons: electrophysiological evidence for at least two different binding sites Neuroscience letters, 1996, Sep-20, Volume: 216, Issue:1 Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Binding Sites; Cells, Cultured; Cerebral Cortex; Coloring Agents; Electrophysiology; Evans Blue; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Kinetics; Neurons; Patch-Clamp Techniques; Rats; Receptors, AMPA	1996
Mechanism underlying the effect of pregnenolone sulfate on the kainate-induced current in cultured chick spinal cord neurons. Neuroscience letters, 1997, Jan-31, Volume: 222, Issue:2 Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Cells, Cultured; Chick Embryo; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Ion Channel Gating; Kainic Acid; Neurons; Patch-Clamp Techniques; Pregnenolone; Receptors, Kainic Acid; Spinal Cord	1997
Neuropeptide Y release from cultured hippocampal neurons: stimulation by glutamate acting at N-methyl-D-aspartate and AMPA receptors. Neuroscience, 1997, Volume: 81, Issue:1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Antibody Specificity; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Calcium; Cells, Cultured; Chromatography, High Pressure Liquid; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Kainic Acid; Magnesium; Neurons; Neuropeptide Y; Quinoxalines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin	1997
Distribution and properties of kainate receptors distinct in the CA3 region of the hippocampus of the guinea pig. Brain research, 1998, Feb-09, Volume: 783, Issue:2 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Anti-Anxiety Agents; Benzodiazepines; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Guinea Pigs; Hippocampus; Kainic Acid; Microinjections; Pressure; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; Time Factors	1998
Kainate receptor-mediated inhibition of presynaptic Ca2+ influx and EPSP in area CA1 of the rat hippocampus. The Journal of physiology, 1998, Jun-15, Volume: 509 ( Pt 3) Topics: Action Potentials; Animals; Anti-Anxiety Agents; Benzodiazepines; Calcium; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Indoles; Kainic Acid; Neuromuscular Depolarizing Agents; Oximes; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Rhodamines; Synaptic Transmission	1998
[31P]/[1H] nuclear magnetic resonance study of mitigating effects of GYKI 52466 on kainate-induced metabolic impairment in perfused rat cerebrocortical slices. Epilepsia, 1998, Volume: 39, Issue:6 Topics: Adenosine Triphosphate; Animals; Anti-Anxiety Agents; Anticonvulsants; Aspartic Acid; Benzodiazepines; Cerebral Cortex; Cerebrospinal Fluid; Energy Metabolism; Excitatory Amino Acid Antagonists; Hydrogen-Ion Concentration; Kainic Acid; Lactates; Magnesium; Magnetic Resonance Spectroscopy; Neuroprotective Agents; Phosphorus Isotopes; Protons; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Status Epilepticus	1998
Binding characteristics of a potent AMPA receptor antagonist [3H]Ro 48-8587 in rat brain. Journal of neurochemistry, 1998, Volume: 71, Issue:1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Brain Chemistry; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Imidazoles; In Situ Hybridization; Kainic Acid; Kinetics; Male; N-Methylaspartate; Quinazolines; Quinoxalines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, AMPA; RNA, Messenger; Tritium	1998
Allosteric regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionate receptors by thiocyanate and cyclothiazide at a common modulatory site distinct from that of 2,3-benzodiazepines. Neuroscience, 1998, Volume: 87, Issue:3 Topics: Allosteric Regulation; Animals; Anti-Anxiety Agents; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Binding Sites; Cells, Cultured; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Hippocampus; Ion Channel Gating; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Oocytes; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Thiocyanates; Xenopus	1998
Ionotropic glutamate receptors in isolated horizontal cells of the rabbit retina. The European journal of neuroscience, 1999, Volume: 11, Issue:3 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Ion Channel Gating; Kainic Acid; Membrane Potentials; N-Methylaspartate; Patch-Clamp Techniques; Quinoxalines; Rabbits; Receptors, AMPA; Receptors, Kainic Acid; Retina	1999
Kainate acts at presynaptic receptors to increase GABA release from hypothalamic neurons. Journal of neurophysiology, 1999, Volume: 82, Issue:2 Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Cells, Cultured; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Hypothalamus; In Vitro Techniques; Kainic Acid; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Presynaptic	1999
NMDA and non-NMDA receptor-mediated excitotoxicity are potentiated in cultured striatal neurons by prior chronic depolarization. Experimental neurology, 1999, Volume: 159, Issue:1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Calcium; Cells, Cultured; Corpus Striatum; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Female; Fetus; GluK2 Kainate Receptor; GluK3 Kainate Receptor; Kainic Acid; Membrane Potentials; N-Methylaspartate; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Potassium Chloride; Pregnancy; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate	1999
D1 dopamine receptor-induced cyclic AMP-dependent protein kinase phosphorylation and potentiation of striatal glutamate receptors. Journal of neurochemistry, 1999, Volume: 73, Issue:6 Topics: Action Potentials; Animals; Anti-Anxiety Agents; Benzazepines; Benzodiazepines; Cells, Cultured; Corpus Striatum; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dopamine Agonists; Dopamine Antagonists; Excitatory Amino Acid Agonists; Kainic Acid; Nerve Tissue Proteins; Patch-Clamp Techniques; Phosphorylation; Protein Processing, Post-Translational; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Dopamine D1; Second Messenger Systems; Synaptic Transmission	1999
Sustained ethanol inhibition of native AMPA receptors on medial septum/diagonal band (MS/DB) neurons. British journal of pharmacology, 2000, Volume: 129, Issue:1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Central Nervous System Depressants; Diagonal Band of Broca; Ethanol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Male; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Septum of Brain; Up-Regulation	2000
Mutation of a glutamate receptor motif reveals its role in gating and delta2 receptor channel properties. Nature neuroscience, 2000, Volume: 3, Issue:4 Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Anti-Anxiety Agents; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Cell Line; Conserved Sequence; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Ion Channel Gating; Kainic Acid; Kidney; Mice; Mice, Neurologic Mutants; Molecular Sequence Data; Mutagenesis; Neuromuscular Depolarizing Agents; Patch-Clamp Techniques; Purkinje Cells; Quinoxalines; Receptors, Glutamate; Transfection	2000
Pharmacological and molecular characterization of glutamate receptors in the MIN6 pancreatic beta-cell line. Neurological research, 2000, Volume: 22, Issue:4 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Biological Transport; Calcium; Cell Survival; DNA Primers; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Islets of Langerhans; Kainic Acid; Protein Kinase C; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spider Venoms; Tumor Cells, Cultured	2000
New non competitive AMPA antagonists. Bioorganic & medicinal chemistry, 2000, Volume: 8, Issue:8 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Disease Models, Animal; Drug Design; Humans; Kainic Acid; Male; Mice; Molecular Structure; Muscarinic Agonists; Oxotremorine; Patch-Clamp Techniques; Purkinje Cells; Rats; Receptors, AMPA; Retina; Seizures; Structure-Activity Relationship	2000
In situ Ca2+ imaging reveals neurotransmitter receptors for glutamate in taste receptor cells. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Nov-01, Volume: 20, Issue:21 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Calcium; Cells, Cultured; Dextrans; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Fluorescent Dyes; Glutamic Acid; In Vitro Techniques; Kainic Acid; Male; Microscopy, Confocal; N-Methylaspartate; Neurotransmitter Agents; Organic Chemicals; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Taste Buds	2000
In vivo, the direct and seizure-induced neuronal cytotoxicity of kainate and AMPA is modified by the non-competitive antagonist, GYKI 52466. Brain research, 2001, Jan-26, Volume: 890, Issue:1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Cell Death; Epilepsy; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Nerve Degeneration; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Seizures	2001
Comparison of excitotoxic profiles of ATPA, AMPA, KA and NMDA in organotypic hippocampal slice cultures. Brain research, 2001, Oct-26, Volume: 917, Issue:1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hippocampus; In Vitro Techniques; Isoxazoles; Kainic Acid; Microtubule-Associated Proteins; N-Methylaspartate; Neuroprotective Agents; Neurotoxins; Nissl Bodies; Nuclear Proteins; Propidium; Propionates; Quinoxalines; Rats; Rats, Wistar	2001
Group I metabotropic glutamate receptors limit AMPA receptor-mediated oligodendrocyte progenitor cell death. European journal of pharmacology, 2001, Jul-27, Volume: 424, Issue:3 Topics: Animals; Anti-Anxiety Agents; Benzoates; Benzodiazepines; Cell Death; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Kainic Acid; Oligodendroglia; Rats; Receptors, AMPA; Receptors, Metabotropic Glutamate; Resorcinols; Stem Cells	2001
Functionally different AMPA-type glutamate receptors in morphologically identified neurons in rat superficial superior colliculus. Neuroscience, 2001, Volume: 108, Issue:1 Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Calcium; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Extracellular Space; In Vitro Techniques; Kainic Acid; Neurons; Rats; Rats, Wistar; Receptors, AMPA; Spermine; Superior Colliculi	2001
A non-excitatory paradigm of glutamate toxicity. Journal of neurophysiology, 2002, Volume: 87, Issue:3 Topics: Action Potentials; Ambystoma; Animals; Anti-Anxiety Agents; Benzodiazepines; Calcium; Cell Death; Excitatory Amino Acid Agonists; Glutamates; Glutamic Acid; Kainic Acid; Neuroprotective Agents; Patch-Clamp Techniques; Receptors, Kainic Acid; Retinal Ganglion Cells	2002
AMPA receptors on developing medial septum/diagonal band neurons are sensitive to early postnatal binge-like ethanol exposure. Brain research. Developmental brain research, 2003, Apr-14, Volume: 142, Issue:1 Topics: Alcohol-Induced Disorders, Nervous System; Alcoholic Intoxication; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Blotting, Western; Cells, Cultured; Central Nervous System Depressants; Diagonal Band of Broca; Ethanol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Kainic Acid; Male; Membrane Potentials; Models, Animal; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA	2003
p21(WAF1/Cip1) is not involved in kainic acid-induced apoptosis in murine cerebellar granule cells. Brain research, 2004, Dec-31, Volume: 1030, Issue:2 Topics: Animals; Apoptosis; Benzodiazepines; Cell Cycle; Cell Cycle Proteins; Cells, Cultured; Cerebellum; Cyclin-Dependent Kinase Inhibitor p21; Excitatory Amino Acid Antagonists; Kainic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Degeneration; Neurons; Quinoxalines; Receptors, AMPA	2004
Glutamate receptor antagonists and benzodiazepine inhibit the progression of granule cell dispersion in a mouse model of mesial temporal lobe epilepsy. Epilepsia, 2005, Volume: 46, Issue:2 Topics: Animals; Benzodiazepines; Cell Count; Dentate Gyrus; Disease Models, Animal; Dizocilpine Maleate; Epilepsy, Temporal Lobe; Excitatory Amino Acid Antagonists; GABA Modulators; Hippocampus; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Midazolam; Mossy Fibers, Hippocampal; Neurons; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate	2005
Apoptosis-inducing factor is a key factor in neuronal cell death propagated by BAX-dependent and BAX-independent mechanisms. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Feb-09, Volume: 25, Issue:6 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Apoptosis Inducing Factor; Apoptotic Protease-Activating Factor 1; bcl-2-Associated X Protein; Benzodiazepines; Benzothiadiazines; Camptothecin; Caspase Inhibitors; Cells, Cultured; Cerebellum; Cerebral Cortex; Convulsants; Dizocilpine Maleate; Drug Resistance; Flavoproteins; Glutamic Acid; Glycine; Hippocampus; Kainic Acid; Male; Membrane Proteins; Mice; Mice, Knockout; Mice, Mutant Strains; N-Methylaspartate; Neurons; Neurotoxins; Proteins; Proto-Oncogene Proteins c-bcl-2; Recombinant Fusion Proteins; Seizures	2005
Glutamate stimulates oligodendrocyte progenitor migration mediated via an alphav integrin/myelin proteolipid protein complex. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Mar-01, Volume: 26, Issue:9 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Genetically Modified; Animals, Newborn; Benzodiazepines; Blotting, Western; Calcium; Carbachol; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Movement; Cells, Cultured; Chelating Agents; Cholinergic Agonists; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fibronectins; Glutamic Acid; Immunohistochemistry; Immunoprecipitation; Integrin alphaV; Ionophores; Kainic Acid; Models, Biological; Myelin Proteolipid Protein; Myelin Sheath; Oligodendroglia; Pertussis Toxin; Quinoxalines; Rats; Receptor, Platelet-Derived Growth Factor alpha; Receptors, AMPA; Ruthenium Red; Stem Cells; Thapsigargin	2006
Neural overexcitation and implication of NMDA and AMPA receptors in a mouse model of temporal lobe epilepsy implying zinc chelation. Epilepsia, 2006, Volume: 47, Issue:5 Topics: Animals; Benzodiazepines; Cell Death; Chelating Agents; Disease Models, Animal; Ditiocarb; Dizocilpine Maleate; Epilepsy, Temporal Lobe; Hippocampus; HSP72 Heat-Shock Proteins; Kainic Acid; Male; Mice; Neuroprotective Agents; Proto-Oncogene Proteins c-fos; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Zinc	2006
Presynaptic AMPA and kainate receptors increase the size of GABAergic terminals and enhance GABA release. Neuropharmacology, 2007, Volume: 52, Issue:8 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Benzodiazepines; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Green Fluorescent Proteins; Inhibitory Postsynaptic Potentials; Interneurons; Kainic Acid; Membrane Potentials; Mice; Mice, Transgenic; Presynaptic Terminals; Receptors, AMPA; Receptors, Kainic Acid	2007
Regulation of glutamate transport in developing rat oligodendrocytes. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, Jun-17, Volume: 29, Issue:24 Topics: Animals; Animals, Newborn; Aspartic Acid; Benzodiazepines; Bicuculline; Brain; Cells, Cultured; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Female; Fibroblast Growth Factors; GABA Antagonists; Gangliosides; Gene Expression Regulation, Developmental; Glutamic Acid; Kainic Acid; Membrane Potentials; Neurons; O Antigens; Oligodendroglia; Patch-Clamp Techniques; Platelet-Derived Growth Factor; Pregnancy; Quinoxalines; Rats; Rats, Long-Evans; Sodium Channel Blockers; Tetrodotoxin; Tritium	2009
Treatment of early and late kainic acid-induced status epilepticus with the noncompetitive AMPA receptor antagonist GYKI 52466. Epilepsia, 2010, Volume: 51, Issue:1 Topics: Animals; Anticonvulsants; Behavior, Animal; Benzodiazepines; Blood Pressure; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance; Electrodes, Implanted; Electroencephalography; Frontal Lobe; Kainic Acid; Male; Mice; Receptors, AMPA; Status Epilepticus	2010
Furthering pharmacological and physiological assessment of the glutamatergic receptors at the Drosophila neuromuscular junction. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2009, Volume: 150, Issue:4 Topics: Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Cycloleucine; Dose-Response Relationship, Drug; Drosophila; Electrophysiology; Excitatory Postsynaptic Potentials; Glutamates; Kainic Acid; Larva; Neuromuscular Junction; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Synaptic Transmission	2009
Postnatal change of GluR5 kainate receptor expression in the substantia gelatinosa neuron of the trigeminal subnucleus caudalis in mice. Brain research, 2010, Jul-30, Volume: 1346 Topics: Aging; Animals; Benzodiazepines; Blotting, Western; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Immunohistochemistry; Kainic Acid; Male; Mice; Neurons; Patch-Clamp Techniques; Receptors, Kainic Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substantia Gelatinosa; Tetrodotoxin; Trigeminal Nuclei	2010
Repeated application of 4-aminopyridine provoke an increase in entorhinal cortex excitability and rearrange AMPA and kainate receptors. Neurotoxicity research, 2015, Volume: 27, Issue:4 Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Animals; Benzodiazepines; Entorhinal Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Male; Protein Subunits; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Seizures	2015
Astrocyte-Dependent Vulnerability to Excitotoxicity in Spermine Oxidase-Overexpressing Mouse. Neuromolecular medicine, 2016, Volume: 18, Issue:1 Topics: Animals; Aspartic Acid; Astrocytes; Benzodiazepines; Biogenic Polyamines; Calcium; Cerebral Cortex; Enzyme Induction; Genetic Predisposition to Disease; Gliosis; Hippocampus; Kainic Acid; Male; Metallothionein; Mice; Mice, Neurologic Mutants; Mice, Transgenic; Nerve Tissue Proteins; Neurons; Neurotoxins; Oxidative Stress; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Receptors, AMPA; Recombinant Fusion Proteins; Seizures; Synaptosomes; Up-Regulation	2016
Inhibition of calcium-permeable and calcium-impermeable AMPA receptors by perampanel in rat brain neurons. Neuroscience letters, 2016, 10-28, Volume: 633 Topics: Animals; Anticonvulsants; Benzodiazepines; Benzothiadiazines; Binding Sites; Brain; CA1 Region, Hippocampal; Calcium; Corpus Striatum; Drug Interactions; Glutamic Acid; Interneurons; Kainic Acid; Neurons; Nitriles; Pyramidal Cells; Pyridones; Rats, Wistar; Receptors, AMPA	2016
AMPA receptors and seizures mediate hippocampal radial glia-like stem cell proliferation. Glia, 2018, Volume: 66, Issue:11 Topics: Animals; Animals, Newborn; Benzodiazepines; Cell Death; Cell Proliferation; Cells, Cultured; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Kainic Acid; Ki-67 Antigen; Male; Membrane Potentials; Nerve Tissue Proteins; Neuroglia; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Seizures; Stem Cells	2018