gw420867x has been researched along with nevirapine in 2 studies
| Studies (gw420867x) | Trials (gw420867x) | Recent Studies (post-2010) (gw420867x) | Studies (nevirapine) | Trials (nevirapine) | Recent Studies (post-2010) (nevirapine) |
|---|---|---|---|---|---|
| 17 | 5 | 2 | 3,212 | 509 | 1,108 |
| Protein | Taxonomy | gw420867x (IC50) | nevirapine (IC50) |
|---|---|---|---|
| Chain B, Hiv-1 Reverse Transcriptase | Human immunodeficiency virus 1 | 0.08 | |
| Chain A, Hiv-1 Reverse Transcriptase | Human immunodeficiency virus 1 | 0.08 | |
| Chain A, Hiv-1 Reverse Transcriptase | Human immunodeficiency virus 1 | 0.08 | |
| Chain A, Hiv-1 Reverse Transcriptase | Human immunodeficiency virus 1 | 0.08 | |
| Chain B, Hiv-1 Reverse Transcriptase | Human immunodeficiency virus 1 | 0.08 | |
| Chain A, Reverse transcriptase/ribonuclease H | Human immunodeficiency virus 1 | 1.165 | |
| Prothrombin | Bos taurus (cattle) | 1.15 | |
| Gag-Pol polyprotein | Human immunodeficiency virus type 1 BH10 | 1.4504 | |
| Gag-Pol polyprotein | Human immunodeficiency virus type 2 (ISOLATE ROD) | 2.05 | |
| Gag-Pol polyprotein | HIV-1 M:B_HXB2R | 1.4353 | |
| Imidazoleglycerol-phosphate dehydratase | Saccharomyces cerevisiae S288C | 1.7 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.181 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 0.181 | |
| Gag-Pol polyprotein | Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE) | 0.69 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.7 | |
| Microsomal triglyceride transfer protein large subunit | Homo sapiens (human) | 5.75 | |
| Disintegrin and metalloproteinase domain-containing protein 17 | Homo sapiens (human) | 0.18 | |
| Reverse transcriptase/RNaseH | Human immunodeficiency virus 1 | 2.071 | |
| Protease | Human immunodeficiency virus 1 | 0.101 | |
| Reverse transcriptase | Human immunodeficiency virus 1 | 3.995 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jorgensen, WL; Kroeger Smith, MB; Rizzo, RC; Smith, RH; Tirado-Rives, J; Udier-Blagović, M; Wang, DP; Watkins, EK | 1 |
| Balzarini, J; Burt, V; Carbonez, A; De Clercq, E; Kleim, JP | 1 |
2 other study(ies) available for gw420867x and nevirapine
| Article | Year |
|---|---|
Prediction of activity for nonnucleoside inhibitors with HIV-1 reverse transcriptase based on Monte Carlo simulations.
Topics: Alkynes; Anilides; Benzoxazines; Computer Simulation; Cyclopropanes; HIV Reverse Transcriptase; Hydrogen Bonding; Models, Molecular; Monte Carlo Method; Nevirapine; Oxazines; Protein Binding; Quinoxalines; Regression Analysis; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Uracil | 2002 |
Long-term exposure of HIV type 1-infected cell cultures to combinations of the novel quinoxaline GW420867X with lamivudine, abacavir, and a variety of nonnucleoside reverse transcriptase inhibitors.
Topics: Alkynes; Anilides; Anti-HIV Agents; Benzoxazines; Cell Line; Cyclopropanes; Delavirdine; Dideoxynucleosides; Dose-Response Relationship, Drug; Drug Combinations; Drug Resistance, Microbial; Furans; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Microbial Sensitivity Tests; Mutation; Nevirapine; Oxazines; Quinoxalines; Reverse Transcriptase Inhibitors; Thioamides; Uracil | 2000 |