guvacoline has been researched along with carbachol in 3 studies
| Studies (guvacoline) | Trials (guvacoline) | Recent Studies (post-2010) (guvacoline) | Studies (carbachol) | Trials (carbachol) | Recent Studies (post-2010) (carbachol) |
|---|---|---|---|---|---|
| 11 | 0 | 7 | 13,918 | 81 | 968 |
| Protein | Taxonomy | guvacoline (IC50) | carbachol (IC50) |
|---|---|---|---|
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 0.7849 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 2.0626 | |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | 3.4134 | |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | 2.9961 | |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | 2.535 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 2.9961 | |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | 2.6638 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 4.849 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 4.99 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baker, R; Freedman, SB; Gibbons, TL; Kneen, CO; MacLeod, AM; Merchant, K; Patel, S; Saunders, J; Showell, GA | 1 |
| Baker, R; Freedman, SB; MacLeod, AM; Merchant, KJ; Patel, S; Roe, M; Saunders, J | 1 |
| Falch, E; Krogsgaard-Larsen, P; Larsen, JJ; Sauerberg, P | 1 |
3 other study(ies) available for guvacoline and carbachol
| Article | Year |
|---|---|
Tetrahydropyridyloxadiazoles: semirigid muscarinic ligands.
Topics: Animals; Binding Sites; Chemical Phenomena; Chemistry; Crystallization; Hydrogen Bonding; Male; Molecular Conformation; Molecular Structure; Oxadiazoles; Parasympathomimetics; Pyridines; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Structure-Activity Relationship; Thermodynamics; X-Ray Diffraction | 1991 |
Synthesis and muscarinic activities of 1,2,4-thiadiazoles.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Indicators and Reagents; Kinetics; Ligands; Models, Molecular; Molecular Structure; N-Methylscopolamine; Oxotremorine; Parasympathomimetics; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Structure-Activity Relationship; Thiadiazoles; X-Ray Diffraction | 1990 |
A novel class of conformationally restricted heterocyclic muscarinic agonists.
Topics: Animals; Brain; Guinea Pigs; Ileum; In Vitro Techniques; Molecular Conformation; Parasympathomimetics; Propylbenzilylcholine Mustard; Rats; Receptors, Muscarinic; Structure-Activity Relationship; Tritium | 1986 |