guvacoline has been researched along with arecoline in 10 studies
| Studies (guvacoline) | Trials (guvacoline) | Recent Studies (post-2010) (guvacoline) | Studies (arecoline) | Trials (arecoline) | Recent Studies (post-2010) (arecoline) |
|---|---|---|---|---|---|
| 11 | 0 | 7 | 1,110 | 20 | 271 |
| Protein | Taxonomy | guvacoline (IC50) | arecoline (IC50) |
|---|---|---|---|
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 3.6 | |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | 1.011 | |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | 0.963 | |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | 0.963 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 0.963 | |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | 0.9163 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 0.115 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (60.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baker, R; Freedman, SB; Gibbons, TL; Kneen, CO; MacLeod, AM; Merchant, K; Patel, S; Saunders, J; Showell, GA | 1 |
| Baker, R; Freedman, SB; MacLeod, AM; Merchant, KJ; Patel, S; Roe, M; Saunders, J | 1 |
| Falch, E; Krogsgaard-Larsen, P; Larsen, JJ; Sauerberg, P | 1 |
| Attwa, MW; Kadi, AA; Rahman, AF | 1 |
| Lu, TL; Mao, CQ; Mao, SH; Tang, LJ; Wu, H; Yu, HL | 1 |
| Chandrakumar, N; George, C; Naik, HR; Pinto, DG; Pradeep, T; Srimany, A | 1 |
| Cai, B; Tang, L; Wang, K; Wu, H; Yin, Y; Yu, H; Zhang, C; Zhang, X | 1 |
| Horenstein, NA; Papke, RL; Quadri, M; Shoaib, M; Stokes, C | 1 |
| Grünhofer, P; Schreiber, L; Wan, Y; Wang, S; Wu, J; Yuan, L; Zhang, H | 1 |
| Chong, KW; Chua, NQE; Cirillo, N; Dang, S; Davis, A; Prime, SS; Zhang, P | 1 |
1 review(s) available for guvacoline and arecoline
| Article | Year |
|---|---|
Molecular Mechanisms of Malignant Transformation of Oral Submucous Fibrosis by Different Betel Quid Constituents-Does Fibroblast Senescence Play a Role?
Topics: Areca; Arecoline; Carcinoma, Squamous Cell; Disease Progression; Humans; Mouth Neoplasms; Nicotinic Acids; Oral Submucous Fibrosis; Plant Extracts | 2022 |
9 other study(ies) available for guvacoline and arecoline
| Article | Year |
|---|---|
Tetrahydropyridyloxadiazoles: semirigid muscarinic ligands.
Topics: Animals; Binding Sites; Chemical Phenomena; Chemistry; Crystallization; Hydrogen Bonding; Male; Molecular Conformation; Molecular Structure; Oxadiazoles; Parasympathomimetics; Pyridines; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Structure-Activity Relationship; Thermodynamics; X-Ray Diffraction | 1991 |
Synthesis and muscarinic activities of 1,2,4-thiadiazoles.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Indicators and Reagents; Kinetics; Ligands; Models, Molecular; Molecular Structure; N-Methylscopolamine; Oxotremorine; Parasympathomimetics; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Structure-Activity Relationship; Thiadiazoles; X-Ray Diffraction | 1990 |
A novel class of conformationally restricted heterocyclic muscarinic agonists.
Topics: Animals; Brain; Guinea Pigs; Ileum; In Vitro Techniques; Molecular Conformation; Parasympathomimetics; Propylbenzilylcholine Mustard; Rats; Receptors, Muscarinic; Structure-Activity Relationship; Tritium | 1986 |
A preliminary study of arecoline and guvacoline presence in the saliva of a "betel-quid" chewer using liquid-chromatography ion trap mass spectrometry.
Topics: Adult; Areca; Arecoline; Chromatography, High Pressure Liquid; Humans; Male; Mass Spectrometry; Mastication; Nicotinic Acids; Saliva; Stereoisomerism | 2013 |
[Optimization of Preparation of Cutting-processed Arecae Pericarpium with Multi-index Orthogonal Method].
Topics: Alkaloids; Areca; Arecoline; Drugs, Chinese Herbal; Nicotinic Acids | 2014 |
Developmental patterning and segregation of alkaloids in areca nut (seed of Areca catechu) revealed by magnetic resonance and mass spectrometry imaging.
Topics: Alkaloids; Areca; Arecoline; Humans; India; Magnetic Resonance Imaging; Molecular Structure; Nicotinic Acids; Nuclear Magnetic Resonance, Biomolecular; Nuts | 2016 |
Determination of contents of four alkaloids in Pericarpium arecae by quantitative analysis of multi-components by single-marker.
Topics: Alkaloids; Areca; Arecoline; Chromatography, High Pressure Liquid; Limit of Detection; Nicotinic Acids; Reproducibility of Results | 2016 |
Cracking the Betel Nut: Cholinergic Activity of Areca Alkaloids and Related Compounds.
Topics: Alkaloids; Animals; Areca; Arecoline; Behavior, Addictive; Cells, Cultured; Cholinergic Agents; Humans; Nicotinic Acids; Oocytes; Receptors, Muscarinic; Receptors, Nicotinic; Tobacco Use Disorder; Xenopus laevis | 2019 |
Tissue-specific and maturity-dependent distribution of pyridine alkaloids in Areca triandra.
Topics: Alkaloids; Areca; Arecoline; Chromatography, High Pressure Liquid; Flowers; Fruit; Mass Spectrometry; Nicotinic Acids; Plant Leaves; Pyridines | 2019 |