Compounds > gusperimus
Page last updated: 2024-08-23

gusperimus and tacrolimus

gusperimus has been researched along with tacrolimus in 71 studies

Research

Studies (71)

TimeframeStudies, this research(%)All Research%
pre-19905 (7.04)18.7374
1990's57 (80.28)18.2507
2000's9 (12.68)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
First, MR1
Araneda, D; Carobbi, A; Quarantillo, P; Thomas, FT; Thomas, JM1
Hisanaga, M; Nakajima, Y; Nakano, H; Segawa, M; Ueno, M; Yabuuchi, H; Yoshimura, A1
Hisanaga, M; Nakajima, Y; Nakano, H; Yabuuchi, H1
Thomson, AW1
Morris, RE1
Iga, C; Okajima, K; Takeda, Y; Tezuka, K1
Hiraiwa, T; Katayama, Y; Kusagawa, M; Namikawa, S; Onoda, K; Takao, M; Yada, I1
Hisanaga, M; Kanehiro, H; Murao, Y; Nakagawa, K; Nakajima, Y; Nakano, H; Segawa, M; Wada, T; Yabuuchi, H; Yoshimura, A1
Simmons, RL; Wang, SC1
Gunji, Y; Isono, K; Nagata, M; Ochiai, T1
Kawashima, H; Mochizuki, M1
Chan, CC; Mochizuki, M; Ni, M; Nussenblatt, RB1
Morris, PJ1
Ishibashi, M; Jiang, H; Kokado, Y; Kyo, M; Sonoda, T; Takahara, S1
Asano, T; Isono, K; Nagata, M; Nakajima, K; Ochiai, T; Sakamoto, K1
Dohi, K; Fukuda, Y; Inagaki, K; Ito, H; Matsuno, K; Sumimoto, K; Takahashi, M1
Asano, T; Isono, K; Nakajima, K; Ochiai, T; Sakamoto, K1
Asano, T; Gunji, Y; Hamaguchi, K; Isono, K; Nagata, M; Nakajima, K; Ochiai, T; Sakamaki, T; Sakamoto, K1
Ishibashi, M; Jiang, S; Kokado, Y; Sonoda, T; Takahara, S1
Beer, E; Cho, SI; Jindal, RM; Soltys, K; Tepper, MA; Yost, F1
Fukuzaki, T; Gotoh, M; Hasuike, Y; Kanai, T; Monden, M; Mori, T; Nagano, H; Tanigawa, T; Umeshita, K1
Engelbrecht, ME; Myburgh, JA; Oosthuizen, MM1
Ishibashi, M; Jiang, H; Li, D; Namiki, M; Okuyama, A; Sonoda, T; Takahara, S2
Suzuki, S1
Surdacka, E; Surdacki, A; Sułowicz, W1
Groth, CG; Karlsson-Parra, A; Korsgren, O; Kozlowski, T; Sundberg, B; Tibell, A; Wallgren, AC; Wennberg, L1
Arita, S; Asano, T; Enomoto, K; Isono, K; Kenmochi, T; Ochiai, T1
Holmes, JA; Twentyman, PR1
Kahan, BD1
Demetris, AJ; Miyazawa, H; Murase, N; Nakamura, K; Starzl, TE; Tanabe, M; Valdivia, LA1
Billingham, ME; Dzau, VJ; Gregory, CR; Huie, P; Morris, RE; Pratt, RE; Shorthouse, R1
Hirao, A; Kawano, Y; Takaue, Y1
Aono, T; Koyama, S; Muto, T; Ohtake, M; Okamura, N; Sakaguchi, T; Tsukada, K; Yoshida, K1
Bumgardner, GL; Roberts, JP1
Kanehiro, H; Nakajima, Y; Nakano, H; Ueno, M; Yoshimura, A1
Ericzon, BG; Gannedahl, G; Groth, CG; Ohlman, S1
Groth, CG1
Bersztel, A; Ekberg, H; Gannedahl, G; Olausson, M; Tufveson, G; Wadström, J; Wanders, A1
Bailey, LL; Bouchart, F; Fukushima, N; Gundry, SR; Matsumiya, G; Zuppan, C1
Andereggen, E; Bubloz, C; Bühler, L; Deng, S; Fournier, B; Morel, P1
Fiedor, PS; Goodman, ER; Hardy, MA; Quadracci, KM; Sung, RS; Yaron, I; Zakheim, AR1
Akiyama, T; Amemiya, H; Fukunishi, T; Hanafusa, T; Ichikawa, Y; Ihara, H; Ito, K; Kokado, Y; Kurita, T; Kyo, M; Nagano, S; Okuyama, A; Sagawa, S; Sonoda, T; Suzuki, S; Takahara, S1
Gruessner, AC; Gruessner, RW; Matas, AJ; Moon, C; Nakhleh, RE; Papalois, BE; Sehgal, SN; Troppmann, C1
Borg, AJ; Kumagai-Braesch, M; Möller, E1
Mignat, C1
Katoh, H; Ohi, R; Ohkohchi, N; Satomi, S; Shimaoka, S1
Abo, T; Hatakeyama, K; Iiai, T; Kawachi, Y; Moroda, T; Suzuki, S; Tada, T; Tsukahara, A; Watanabe, H1
Maeda, T1
Waer, M1
Akino, T; Doi, K; Kawai, S; Muramatsu, K; Shigetomi, M1
Cichon, G; Strauss, M1
Katagiri, A; Nakagawa, Y; Saito, K; Sonda, K; Takahashi, K; Takeda, M; Tanigawa, T; Tomita, Y1
Bonham, CA; Gerber, DA; Thomson, AW1
Asakura, T; Doi, H; Fujimori, K; Katoh, H; Kawagishi, N; Kikuchi, H; Koyamada, N; Ohkohchi, N; Oikawa, K; Orii, T; Sakurada, M; Satake, M; Satomi, S; Takayama, J1
Chatzipetrou, M; Kenyon, NS; Masetti, M; Ranuncoli, A; Ricordi, C1
Doi, K; Kawai, S; Muramatsu, K1
Bonkohara, Y; Hachida, M; Koyanagi, H; Maeda, T; Niinami, H; Nonoyama, M1
Amemiya, H; Enosawa, S; Funeshima, N; Kakefuda, T; Kanashiro, M; Kitajima, M; Li, XK; Suzuki, S; Tamura, A1
Korsgren, O; Tibell, A; Wennberg, L; Wu, GS1
Fuchinoue, S; Harano, M; Ichikura, H; Inui, M; Ishikawa, N; Ito, S; Manu, M; Okuda, H; Shimmura, H; Shimuzu, T; Tanabe, K; Tokumoto, T; Toma, H; Yagisawa, T1
Ebisui, C; Fukunishi, T; Hanafusa, T; Ichikawa, Y; Kyo, M; Nagano, S; Nojima, M; Tsubakihara, Y; Yazawa, K1
Chubachi, S; Doi, H; Haga, I; Kawagishi, N; Kikuchi, H; Koyamada, N; Nakajima, N; Oguma, S; Ohkohchi, N; Orii, T; Satomi, S; Sekiguchi, S1
Diaz-Romero, J; Vogt, G; Weckbecker, G1
Dumont, FJ1
Simpson, D1
Groth, CG; Hagberg, A; Korsgren, O; Krook, H; Song, Z; Wennberg, L1
Amada, N; Kikuchi, H; Ohashi, Y; Okazaki, H; Sato, T1
Matl, I1

Reviews

18 review(s) available for gusperimus and tacrolimus

ArticleYear
The spectrum of action of new immunosuppressive drugs.
    Clinical and experimental immunology, 1992, Volume: 89, Issue:2

    Topics: Animals; Biphenyl Compounds; Cyclosporine; Guanidines; Humans; Immunosuppressive Agents; Polyenes; Sirolimus; Tacrolimus

1992
Immunopharmacology of new xenobiotic immunosuppressive molecules.
    Seminars in nephrology, 1992, Volume: 12, Issue:4

    Topics: Animals; Biphenyl Compounds; Cyclosporine; Graft Rejection; Guanidines; Humans; Immunosuppressive Agents; Mycophenolic Acid; Polyenes; Ribonucleosides; Sirolimus; Tacrolimus; Xenobiotics

1992
New horizons in immunosuppression.
    Transplantation proceedings, 1991, Volume: 23, Issue:4

    Topics: Anti-Bacterial Agents; Cyclosporins; Guanidines; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Molecular Structure; Mycophenolic Acid; Polyenes; Sirolimus; Tacrolimus; Transplantation Immunology

1991
[Immunosuppressive agents--advances of the developmental studies and the mode of action].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Cyclosporins; Graft Survival; Guanidines; Humans; Immunosuppressive Agents; Mycophenolic Acid; Polyenes; Sirolimus; Tacrolimus; Transplantation

1991
Cyclosporine, FK-506 and other drugs in organ transplantation.
    Current opinion in immunology, 1991, Volume: 3, Issue:5

    Topics: Cyclosporine; Guanidines; Humans; Mycophenolic Acid; Polyenes; Signal Transduction; Sirolimus; T-Lymphocytes; Tacrolimus; Transplantation Immunology

1991
FK506 and deoxyspergualin: experimental studies and clinical applications.
    Transplant immunology, 1994, Volume: 2, Issue:3

    Topics: Adult; Animals; B-Lymphocytes; Child; Guanidines; Heart Transplantation; Humans; Immunosuppressive Agents; Liver Transplantation; Randomized Controlled Trials as Topic; T-Lymphocytes; Tacrolimus

1994
[New immunosuppressive drugs in transplantation].
    Przeglad lekarski, 1994, Volume: 51, Issue:8

    Topics: Biphenyl Compounds; Cyclosporine; Guanidines; Humans; Immunosuppressive Agents; Mycophenolic Acid; Polyenes; Ribonucleosides; Sirolimus; Spiro Compounds; Tacrolimus; Transplantation Immunology

1994
New immunosuppressive drugs--pharmacologic approaches to alter immunoregulation.
    Therapeutic immunology, 1994, Volume: 1, Issue:1

    Topics: Animals; Antimetabolites; Azathioprine; Biphenyl Compounds; Cell Differentiation; Cyclosporine; Guanidines; Humans; Immunosuppressive Agents; Isoxazoles; Leflunomide; Lymphocytes; Lymphokines; Oligonucleotides, Antisense; Polyenes; Receptors, Cytokine; Ribonucleosides; Signal Transduction; Sirolimus; Tacrolimus

1994
New immunosuppressive agents.
    Gastroenterology clinics of North America, 1993, Volume: 22, Issue:2

    Topics: Alprostadil; Animals; Antibodies, Monoclonal; Biphenyl Compounds; Child; Disease Models, Animal; Dogs; Guanidines; Humans; Immunosuppressive Agents; Liver Transplantation; Mycophenolic Acid; Polyenes; Rats; Sirolimus; Tacrolimus

1993
New immunosuppressive drugs in transplantation.
    Transplantation proceedings, 1993, Volume: 25, Issue:4

    Topics: Biphenyl Compounds; Cyclosporins; Guanidines; Humans; Immunosuppressive Agents; Kidney; Mycophenolic Acid; Polyenes; Sirolimus; T-Lymphocytes; Tacrolimus; Transplantation Immunology

1993
Immunosuppressive regimens of tomorrow.
    Transplantation proceedings, 1995, Volume: 27, Issue:6

    Topics: Animals; Clinical Trials as Topic; Guanidines; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Mycophenolic Acid; Polyenes; Sirolimus; Tacrolimus; Transplantation Immunology

1995
Clinically significant drug interactions with new immunosuppressive agents.
    Drug safety, 1997, Volume: 16, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Cytochrome P-450 Enzyme System; Drug Design; Drug Interactions; Guanidines; Humans; Immunosuppressive Agents; Kidney; Liver; Mycophenolic Acid; Polyenes; Sirolimus; Tacrolimus

1997
New immunosuppressive agents for organ transplantation.
    Acta clinica Belgica, 1997, Volume: 52, Issue:4

    Topics: Graft Rejection; Guanidines; Humans; Immunosuppressive Agents; Isoxazoles; Leflunomide; Mycophenolic Acid; Nitriles; Organ Transplantation; Polyenes; Sirolimus; Tacrolimus

1997
Immunosuppressive agents: recent developments in molecular action and clinical application.
    Transplantation proceedings, 1998, Volume: 30, Issue:4

    Topics: Cyclosporine; Guanidines; Humans; Immunosuppressive Agents; Isoxazoles; Leflunomide; Models, Biological; Mycophenolic Acid; Polyenes; Ribonucleosides; Sirolimus; T-Lymphocytes; Tacrolimus; Transplantation Immunology

1998
Islet transplantation: present and future perspectives.
    Diabetes/metabolism reviews, 1998, Volume: 14, Issue:4

    Topics: Clinical Trials as Topic; Cyclosporine; Diabetes Mellitus, Type 1; Graft Rejection; Guanidines; Humans; Immunosuppressive Agents; Islets of Langerhans Transplantation; Tacrolimus; Tissue Donors

1998
Treatment of transplant rejection: are the traditional immunosuppressants good enough?
    Current opinion in investigational drugs (London, England : 2000), 2001, Volume: 2, Issue:3

    Topics: Antibodies, Monoclonal; Antimetabolites; Calcineurin Inhibitors; Cyclosporine; Cytokines; Drug Design; Fingolimod Hydrochloride; Graft Rejection; Guanidines; Humans; Immunosuppressive Agents; Lymphocyte Activation; Molecular Structure; Organ Transplantation; Propylene Glycols; Signal Transduction; Sirolimus; Sphingosine; T-Lymphocytes; Tacrolimus; Triterpenes

2001
New developments in the prophylaxis and treatment of graft versus host disease.
    Expert opinion on pharmacotherapy, 2001, Volume: 2, Issue:7

    Topics: Abatacept; Alemtuzumab; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antigens, CD; Antigens, Differentiation; Antimetabolites; Bone Marrow Transplantation; CD40 Ligand; Clinical Trials as Topic; CTLA-4 Antigen; Cyclosporine; Drug Design; Graft vs Host Disease; Guanidines; Guidelines as Topic; Humans; Immunoconjugates; Immunosuppression Therapy; Immunosuppressive Agents; Kidney Transplantation; Methotrexate; Mycophenolic Acid; Sirolimus; T-Lymphocytes; Tacrolimus

2001
[Newer immunosuppressive agents and their place in current practice].
    Casopis lekaru ceskych, 2000, Aug-02, Volume: 139, Issue:15

    Topics: Antibodies, Monoclonal; Guanidines; Humans; Immunosuppressive Agents; Mycophenolic Acid; Receptors, Interleukin-2; Sirolimus; Tacrolimus

2000

Trials

3 trial(s) available for gusperimus and tacrolimus

ArticleYear
Living related partial liver transplantation in biliary atresia: 11 cases of experience.
    The Tohoku journal of experimental medicine, 1997, Volume: 181, Issue:1

    Topics: ABO Blood-Group System; Biliary Atresia; Child, Preschool; Female; Graft Rejection; Guanidines; Histocompatibility; Humans; Immunosuppressive Agents; Infant; Japan; Liver Transplantation; Living Donors; Male; Postoperative Complications; Survival Rate; T-Lymphocytes; Tacrolimus

1997
Tacrolimus therapy for ABO-incompatible kidney transplantation.
    Transplantation proceedings, 1998, Volume: 30, Issue:4

    Topics: ABO Blood-Group System; Adult; Antilymphocyte Serum; Azathioprine; Blood Group Incompatibility; Drug Therapy, Combination; Graft Rejection; Graft Survival; Guanidines; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Methylprednisolone; Middle Aged; Survival Rate; Tacrolimus

1998
Deoxyspergualin prophylaxis with tacrolimus further improves long-term graft survival in living-related renal-transplant recipients transfused with donor-specific blood.
    Transplantation proceedings, 2005, Volume: 37, Issue:2

    Topics: Acute Disease; Blood Transfusion; Creatinine; Drug Therapy, Combination; Follow-Up Studies; Graft Rejection; Graft Survival; Guanidines; Humans; Immunosuppressive Agents; Incidence; Kidney Transplantation; Living Donors; Tacrolimus; Time Factors; Transplantation Conditioning

2005

Other Studies

50 other study(ies) available for gusperimus and tacrolimus

ArticleYear
Renal transplantation for the nephrologist: new immunosuppressive drugs.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1992, Volume: 19, Issue:1

    Topics: Animals; Guanidines; Humans; Immunosuppressive Agents; Kidney Transplantation; Mycophenolic Acid; Polyenes; Ribonucleosides; Sirolimus; Spiro Compounds; Tacrolimus

1992
Synergism of splenectomy and immunosuppressive drugs in prolongation of cardiac xenograft survival.
    Transplantation proceedings, 1992, Volume: 24, Issue:2

    Topics: Animals; Combined Modality Therapy; Cricetinae; Cyclosporine; Graft Survival; Guanidines; Heart Transplantation; Immunosuppressive Agents; Male; Mesocricetus; Rats; Rats, Inbred Lew; Splenectomy; Tacrolimus; Transplantation, Heterologous

1992
Immunosuppressive effect in combination therapy of cyclosporine A, FK 506, and 15-deoxyspergualin on pancreatic islet xenotransplantation.
    Transplantation proceedings, 1992, Volume: 24, Issue:2

    Topics: Animals; Cricetinae; Cyclosporine; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Graft Rejection; Graft Survival; Guanidines; Immunosuppression Therapy; Immunosuppressive Agents; Islets of Langerhans Transplantation; Male; Mesocricetus; Rats; Rats, Inbred Strains; T-Lymphocytes; Tacrolimus; Thymus Gland; Transplantation, Heterologous

1992
Successful combination therapy with FK 506 and 15-deoxyspergualin in pancreatic islet xenografting.
    Transplantation proceedings, 1992, Volume: 24, Issue:3

    Topics: Animals; Antilymphocyte Serum; Blood Glucose; Cricetinae; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Graft Rejection; Graft Survival; Guanidines; Immunosuppressive Agents; Islets of Langerhans Transplantation; Male; Mesocricetus; Rats; Rats, Inbred Strains; Tacrolimus; Time Factors; Transplantation, Heterologous

1992
Prolonged survival of small intestinal allograft in the rat with cyclosporine A, FK 506, and 15-deoxyspergualin.
    Transplantation proceedings, 1990, Volume: 22, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Cyclosporins; Graft Survival; Guanidines; Immunosuppressive Agents; Intestine, Small; Rats; Rats, Inbred F344; Rats, Inbred Lew; Tacrolimus; Transplantation, Heterotopic

1990
Immunosuppressive effects of FK 506 and 15-deoxyspergualin in rat lung transplantation.
    Transplantation proceedings, 1991, Volume: 23, Issue:1 Pt 1

    Topics: Animals; Anti-Bacterial Agents; Graft Rejection; Guanidines; Immunosuppressive Agents; Lung Transplantation; Male; Rats; Rats, Inbred F344; Rats, Inbred Strains; Tacrolimus; Transplantation, Homologous

1991
Prominent prolongation of islet xenograft survival in combination therapy with FK 506 and 15-deoxyspergualin.
    Transplantation proceedings, 1991, Volume: 23, Issue:1 Pt 1

    Topics: Animals; Anti-Bacterial Agents; Cricetinae; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Graft Survival; Guanidines; Immunosuppressive Agents; Mesocricetus; Rats; Rats, Inbred Strains; Tacrolimus; Thymus Gland; Transplantation, Heterologous

1991
Effects of FK506, 15-deoxyspergualin, and cyclosporine on experimental autoimmune uveoretinitis in the rat.
    Autoimmunity, 1990, Volume: 8, Issue:1

    Topics: Animals; Antibodies; Antigens; Arrestin; Autoimmune Diseases; Body Weight; Cyclosporine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation, Preclinical; Enzyme-Linked Immunosorbent Assay; Eye; Eye Proteins; Guanidines; Immunosuppressive Agents; Male; Rats; Rats, Inbred Lew; Tacrolimus; Uveitis

1990
FR900506 (FK506) and 15-deoxyspergualin (15-DSG) modulate the kinetics of infiltrating cells in eyes with experimental autoimmune uveoretinitis.
    Autoimmunity, 1990, Volume: 8, Issue:1

    Topics: Animals; Antigens; Arrestin; Autoimmune Diseases; Cyclosporine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Eye Proteins; Guanidines; Immunoenzyme Techniques; Immunosuppressive Agents; Macrophages; Male; Rats; Rats, Inbred Lew; Retina; T-Lymphocyte Subsets; Tacrolimus; Uveitis

1990
Effect of FK-506 on heart allograft survival in the highly sensitized recipient rats as compared with ciclosporin and 15-deoxyspergualin.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1991, Volume: 23, Issue:3-4

    Topics: Animals; Cyclosporins; Graft Survival; Guanidines; Heart Transplantation; Immunization; Immunosuppressive Agents; Male; Rats; Rats, Inbred Lew; Tacrolimus; Transplantation, Homologous

1991
Prolongation of cardiac xenograft survival in rats treated with 15-deoxyspergualin alone and in combination with FK506.
    Transplantation, 1988, Volume: 45, Issue:6

    Topics: Animals; Cricetinae; Drug Therapy, Combination; Graft Survival; Guanidines; Heart Transplantation; Immunosuppressive Agents; Male; Mesocricetus; Pyridines; Rats; Rats, Inbred F344; Tacrolimus; Transplantation, Heterologous

1988
Effects of FK506 and 15-deoxyspergualin in rat orthotopic liver transplantation.
    Transplantation proceedings, 1989, Volume: 21, Issue:1 Pt 1

    Topics: Animals; Cyclosporins; Graft Survival; Guanidines; Immunosuppressive Agents; Liver Transplantation; Male; Pyridines; Rats; Rats, Inbred Lew; Rats, Inbred Strains; Tacrolimus; Transplantation, Homologous

1989
Effects of 15-deoxyspergualin and FK506 on the histology and survival of hamster-to-rat cardiac xenotransplantation.
    Transplantation proceedings, 1989, Volume: 21, Issue:1 Pt 1

    Topics: Animals; Cricetinae; Graft Survival; Guanidines; Heart; Heart Transplantation; Immunosuppressive Agents; Male; Mesocricetus; Myocardium; Pyridines; Rats; Rats, Inbred F344; Tacrolimus

1989
Comparative studies on the immunosuppressive activity of FK506, 15-deoxyspergualin, and cyclosporine.
    Transplantation proceedings, 1989, Volume: 21, Issue:1 Pt 1

    Topics: Animals; Cells, Cultured; Cyclosporins; Graft Rejection; Graft Survival; Guanidines; Heart Transplantation; Humans; Immunosuppressive Agents; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Male; Mice; Mice, Inbred C3H; Pyridines; Rats; Rats, Inbred Strains; Tacrolimus; Transplantation, Heterologous; Transplantation, Homologous

1989
Immunopharmacologic effects of immunosuppressive agents explored by a new effector monocyte generation assay.
    Transplantation proceedings, 1989, Volume: 21, Issue:1 Pt 2

    Topics: Azathioprine; Cells, Cultured; Colony-Forming Units Assay; Cyclosporins; Drug Therapy, Combination; Graft Rejection; Graft Survival; Guanidines; Humans; Immunosuppressive Agents; Kidney Transplantation; Monocytes; Prednisolone; Pyridines; Ribonucleosides; Tacrolimus; Transplantation, Homologous

1989
Effect of deoxyspergualin on the endocrine function of the rat pancreas.
    Transplantation, 1993, Volume: 56, Issue:5

    Topics: Animals; Blood Glucose; Glucose Tolerance Test; Graft Rejection; Guanidines; Immunosuppressive Agents; Islets of Langerhans; Male; Pancreas Transplantation; Rats; Rats, Wistar; Tacrolimus

1993
Nonvascularized islet xenograft rejection in a mouse-to-rat combination where the vascularized heart is rapidly rejected.
    Transplantation proceedings, 1994, Volume: 26, Issue:2

    Topics: Animals; Coronary Vessels; Graft Rejection; Guanidines; Heart Transplantation; Immunosuppressive Agents; Islets of Langerhans Transplantation; Mice; Mice, Inbred BALB C; Rats; Rats, Inbred Strains; T-Lymphocytes; Tacrolimus; Time Factors; Transplantation, Heterologous

1994
The effect of immunosuppressants on human leukocyte NADPH oxidase.
    Annals of the New York Academy of Sciences, 1994, Jun-17, Volume: 723

    Topics: Antigen-Presenting Cells; Azathioprine; Cyclosporine; Guanidines; Humans; Immunosuppressive Agents; In Vitro Techniques; Monocytes; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Polyenes; Sirolimus; Tacrolimus

1994
FK 506 and deoxyspergualin: additive immunosuppressive effect on rat cardiac allograft rejection in vivo and mitogen-stimulated human lymphocyte responses in vitro.
    Transplantation proceedings, 1994, Volume: 26, Issue:4

    Topics: Animals; Cells, Cultured; Drug Therapy, Combination; Graft Rejection; Graft Survival; Guanidines; Heart Transplantation; Humans; Immunosuppressive Agents; Lymphocyte Activation; Lymphocytes; Male; Mitogens; Muromonab-CD3; Rats; Rats, Inbred ACI; Rats, Inbred Lew; Tacrolimus; Transplantation, Homologous; Transplantation, Isogeneic

1994
The superior effect of the combination of FK 506 and deoxyspergualin on rat cardiac allograft survival.
    Transplant international : official journal of the European Society for Organ Transplantation, 1994, Volume: 7, Issue:5

    Topics: Animals; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Graft Survival; Guanidines; Heart; Heart Transplantation; Immunosuppressive Agents; Injections, Intramuscular; Injections, Intraperitoneal; Male; Rats; Rats, Inbred ACI; Rats, Inbred Lew; Tacrolimus; Transplantation, Homologous

1994
Efficacy of various immunosuppressive drugs in preventing pig-to-rat islet xenograft rejection.
    Transplantation proceedings, 1995, Volume: 27, Issue:1

    Topics: Animals; Cyclophosphamide; Cyclosporine; Fetal Tissue Transplantation; Graft Rejection; Graft Survival; Guanidines; Immunosuppressive Agents; Islets of Langerhans Transplantation; Killer Cells, Natural; Macrophages; Male; Mycophenolic Acid; Polyenes; Prednisolone; Rats; Rats, Inbred Lew; Sirolimus; Swine; T-Lymphocytes; Tacrolimus; Transplantation, Heterologous

1995
Effect of FK 506 in experimental pancreas transplantation.
    Transplantation proceedings, 1995, Volume: 27, Issue:2

    Topics: Animals; Dogs; Dose-Response Relationship, Drug; Graft Survival; Guanidines; Immunosuppression Therapy; Immunosuppressive Agents; Pancreas Transplantation; Pancreatectomy; Tacrolimus; Transplantation, Homologous

1995
The activity of deoxyspergualin in multidrug-resistant cells.
    Cancer chemotherapy and pharmacology, 1995, Volume: 36, Issue:6

    Topics: Animals; Antibiotics, Antineoplastic; Cattle; Cyclosporine; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Guanidines; Horses; Humans; Membrane Proteins; Mice; Spermidine; Spermine; Tacrolimus; Tumor Cells, Cultured

1995
[Experimental and clinical studies on the effectiveness of new immunosuppressive agents used in heart transplantation and transplantation-related complications].
    [Zasshi] [Journal]. Nihon Kyobu Geka Gakkai, 1995, Volume: 43, Issue:5

    Topics: Animals; Coronary Disease; Graft Rejection; Guanidines; Heart Transplantation; Humans; Immunosuppressive Agents; Rats; Tacrolimus

1995
Effect of FK 506 and antiproliferative agents for heart and liver xenotransplantation from hamster to rat.
    Transplantation proceedings, 1993, Volume: 25, Issue:1 Pt 1

    Topics: Animals; Antibodies; Antineoplastic Agents; Azathioprine; Biphenyl Compounds; Cricetinae; Cyclophosphamide; Graft Survival; Guanidines; Heart Transplantation; Immunosuppressive Agents; Liver Transplantation; Male; Mesocricetus; Methotrexate; Mycophenolic Acid; Rats; Rats, Inbred Lew; Ribonucleosides; Tacrolimus; Transplantation, Heterologous

1993
Effects of treatment with cyclosporine, FK 506, rapamycin, mycophenolic acid, or deoxyspergualin on vascular muscle proliferation in vitro and in vivo.
    Transplantation proceedings, 1993, Volume: 25, Issue:1 Pt 1

    Topics: Animals; Aorta; Carotid Arteries; Carotid Artery Injuries; Cell Division; Cells, Cultured; Cyclosporine; Guanidines; Immunosuppressive Agents; Male; Muscle, Smooth, Vascular; Mycophenolic Acid; Polyenes; Rats; Rats, Sprague-Dawley; Sirolimus; Tacrolimus

1993
Effects of immunosuppressants, FK506, deoxyspergualin, and cyclosporine A on immature human hematopoiesis.
    Blood, 1993, Mar-01, Volume: 81, Issue:5

    Topics: Antigens, CD; Antigens, CD34; Child; Cyclosporine; Guanidines; Hematopoiesis; Hematopoietic Stem Cells; Humans; Immunosuppressive Agents; Interleukin-3; Tacrolimus

1993
Enhanced liver regeneration in rats treated with 15-deoxyspergualin alone and in combination with FK 506.
    Gastroenterologia Japonica, 1993, Volume: 28, Issue:2

    Topics: Animals; Drug Synergism; Drug Therapy, Combination; Guanidines; Hepatectomy; Immunosuppressive Agents; Liver Regeneration; Lymphocyte Activation; Male; Rats; Rats, Wistar; T-Lymphocytes; Tacrolimus; Time Factors

1993
[Immunosuppressive effect in combination therapy of cyclosporine A, FK506 and 15-deoxyspergualin on a pancreatic islet xenotransplantation].
    Nihon Geka Gakkai zasshi, 1993, Volume: 94, Issue:4

    Topics: Animals; Antilymphocyte Serum; Cricetinae; Cyclosporine; Drug Therapy, Combination; Graft Survival; Guanidines; Immunosuppressive Agents; Islets of Langerhans Transplantation; Male; Mesocricetus; Rats; Rats, Wistar; Tacrolimus; Thymus Gland; Transplantation, Heterologous

1993
Deoxyspergualin is synergistic with cyclosporin A, but not with FK506 in a rat heart allograft transplantation model.
    Transplantation proceedings, 1995, Volume: 27, Issue:6

    Topics: Animals; Cyclosporine; Drug Interactions; Drug Synergism; Guanidines; Heart Transplantation; Immunosuppressive Agents; Male; Rats; Rats, Inbred WKY; Tacrolimus; Transplantation, Homologous

1995
Histological findings in heart grafts after orthotopic pig to baboon cardiac transplantation.
    Transplantation proceedings, 1996, Volume: 28, Issue:2

    Topics: Animals; Animals, Newborn; Cyclosporine; Edema; Female; Graft Rejection; Graft Survival; Guanidines; Heart Transplantation; Hemorrhage; Immunosuppressive Agents; Male; Methotrexate; Necrosis; Papio; Splenectomy; Swine; Tacrolimus; Time Factors; Transplantation, Heterologous

1996
Immunohistological study of islet xenograft rejection in immunosuppressed recipients.
    Transplantation proceedings, 1996, Volume: 28, Issue:2

    Topics: Animals; CD3 Complex; CD4 Antigens; CD8 Antigens; Cyclosporine; Diabetes Mellitus, Experimental; Graft Rejection; Graft Survival; Guanidines; Immunoglobulins; Immunohistochemistry; Immunosuppressive Agents; Islets of Langerhans Transplantation; Macrophage-1 Antigen; Mice; Mice, Inbred C57BL; Rats; Rats, Sprague-Dawley; Receptors, Interleukin-2; Tacrolimus; Transplantation, Heterologous

1996
Survival of human islet xenografts irradiated with ultraviolet B in diabetic rats.
    Transplantation proceedings, 1996, Volume: 28, Issue:2

    Topics: Animals; Antilymphocyte Serum; Cells, Cultured; Diabetes Mellitus, Experimental; Graft Rejection; Graft Survival; Guanidines; Humans; Immunosuppressive Agents; Insulin; Insulin Secretion; Islets of Langerhans; Islets of Langerhans Transplantation; Rats; Rats, Inbred Lew; Tacrolimus; Transplantation, Heterologous; Ultraviolet Rays

1996
Results with histological diagnosis in kidney transplant rejections treated with 15-deoxyspergualin.
    Transplantation proceedings, 1996, Volume: 28, Issue:2

    Topics: Adult; Azathioprine; Cyclosporine; Drug Therapy, Combination; Female; Follow-Up Studies; Graft Rejection; Graft Survival; Guanidines; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Methylprednisolone; Retrospective Studies; Ribonucleosides; Tacrolimus; Time Factors

1996
Perioperative immunosuppression as a critical determinant of early outcome after discordant xenoislet transplantation: a comparative study.
    Transplantation proceedings, 1996, Volume: 28, Issue:2

    Topics: Animals; Blood Glucose; Cyclosporine; Diabetes Mellitus, Experimental; Dogs; Drug Administration Schedule; Drug Therapy, Combination; Graft Survival; Guanidines; Immunosuppression Therapy; Immunosuppressive Agents; Islets of Langerhans Transplantation; Polyenes; Rats; Rats, Inbred Lew; Sirolimus; Tacrolimus; Transplantation, Heterologous

1996
15-Deoxyspergualin inhibits interleukin 6 production in in vitro stimulated human lymphocytes.
    Transplant immunology, 1996, Volume: 4, Issue:2

    Topics: Antibodies, Monoclonal; Antigens, CD; B-Lymphocytes; CD3 Complex; CD4-CD8 Ratio; Cells, Cultured; Concanavalin A; Guanidines; Humans; Immunosuppressive Agents; Interleukin-2; Interleukin-6; Lipopolysaccharides; Lymphocyte Activation; Phytohemagglutinins; Receptors, Interleukin; Receptors, Interleukin-6; Staphylococcus aureus; T-Lymphocytes, Cytotoxic; Tacrolimus

1996
Self-reactive forbidden clones are confined to pathways of intermediate T-cell receptor cell differentiation even under immunosuppressive conditions.
    Immunology, 1997, Volume: 91, Issue:1

    Topics: Animals; CD3 Complex; Cell Differentiation; Cyclosporine; Cytotoxicity, Immunologic; Guanidines; Immunophenotyping; Immunosuppressive Agents; Liver; Mice; Mice, Inbred C3H; Receptors, Antigen, T-Cell; Self Tolerance; Spleen; T-Lymphocyte Subsets; Tacrolimus; Thymus Gland

1997
[Experimental study of the effectiveness of immunosuppression therapy using FK506 and 15-deoxyspergualin in concordant xenotransplantation].
    [Zasshi] [Journal]. Nihon Kyobu Geka Gakkai, 1997, Volume: 45, Issue:6

    Topics: Animals; Cricetinae; Drug Therapy, Combination; Graft Survival; Guanidines; Heart Transplantation; Immunosuppressive Agents; Mesocricetus; Rats; Rats, Inbred Lew; Tacrolimus; Transplantation, Heterologous; Transplantation, Heterotopic

1997
Longer survival of rat limb allograft. Combined immunosuppression of FK-506 and 15-deoxyspergualin.
    Acta orthopaedica Scandinavica, 1997, Volume: 68, Issue:6

    Topics: Animals; Cyclosporine; Drug Synergism; Graft Survival; Guanidines; Hindlimb; Immunosuppressive Agents; Rats; Rats, Inbred Lew; Rats, Inbred Strains; Tacrolimus; Transplantation, Homologous

1997
Transient immunosuppression with 15-deoxyspergualin prolongs reporter gene expression and reduces humoral immune response after adenoviral gene transfer.
    Gene therapy, 1998, Volume: 5, Issue:1

    Topics: Adenoviridae; alpha 1-Antitrypsin; Animals; Antibodies, Viral; beta-Galactosidase; Cyclosporine; Female; Gene Expression; Gene Transfer Techniques; Guanidines; Immunosuppressive Agents; Mice; Mice, Inbred Strains; Statistics, Nonparametric; Tacrolimus; Time Factors

1998
Living related liver transplantation in patients with ABO incompatibility.
    Transplantation proceedings, 1998, Volume: 30, Issue:7

    Topics: ABO Blood-Group System; Biliary Atresia; Blood Group Incompatibility; Child; Child, Preschool; Cyclosporine; Drug Administration Schedule; Female; Guanidines; Humans; Immunosuppressive Agents; Infant; Liver Transplantation; Living Donors; Male; Muromonab-CD3; Parents; Plasma Exchange; Plasmapheresis; Tacrolimus

1998
Limb allotransplantation in rats: combined immunosuppression by FK-506 and 15-deoxyspergualin.
    The Journal of hand surgery, 1999, Volume: 24, Issue:3

    Topics: Animals; Drug Therapy, Combination; Femur; Graft Survival; Guanidines; Hindlimb; Immunosuppressive Agents; Muscle, Skeletal; Rats; Rats, Inbred Lew; Skin; Tacrolimus; Transplantation, Homologous

1999
Combined use of deoxyspergualin and FK 506 for temporary circulatory assist.
    Transplantation proceedings, 1999, Volume: 31, Issue:5

    Topics: Animals; Cricetinae; Graft Rejection; Graft Survival; Guanidines; Heart Transplantation; Immunosuppressive Agents; Mesocricetus; Rats; Rats, Inbred Lew; Rats, Inbred Strains; Tacrolimus; Transplantation, Heterologous

1999
Nitrosyl hemoglobin detected by near-infrared spectroscopy in rat liver allografts.
    Transplant international : official journal of the European Society for Organ Transplantation, 1999, Volume: 12, Issue:5

    Topics: Animals; Graft Rejection; Guanidines; Hemoglobins; Liver Transplantation; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Inbred Lew; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spectroscopy, Near-Infrared; Tacrolimus; Transplantation, Homologous

1999
Deoxyspergualin delays xenograft rejection in the guinea pig-to-C6-deficient rat heart transplantation model.
    Transplant international : official journal of the European Society for Organ Transplantation, 1999, Volume: 12, Issue:6

    Topics: Animals; Antibodies, Heterophile; Combined Modality Therapy; Complement C3; Complement C6; Cyclosporine; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Graft Rejection; Guanidines; Guinea Pigs; Heart Transplantation; Immunity, Cellular; Immunoglobulin G; Immunoglobulin M; Immunosuppressive Agents; Macrophages; Myocardium; Rats; Spleen; Splenectomy; Tacrolimus; Transplantation, Heterologous; Transplantation, Heterotopic

1999
Conversion of renal transplant immunosuppression from tacrolimus (FK 506) to cyclosporine: a single center experience.
    Transplantation proceedings, 2000, Volume: 32, Issue:7

    Topics: Adult; Azathioprine; Cyclosporine; Drug Therapy, Combination; Female; Graft Rejection; Graft Survival; Guanidines; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Methylprednisolone; Middle Aged; Muromonab-CD3; Retrospective Studies; Ribonucleosides; Tacrolimus; Treatment Outcome

2000
Acute rejection and the therapeutic choice of drug.
    Transplantation proceedings, 2000, Volume: 32, Issue:7

    Topics: Acute Disease; Adult; Cyclosporine; Disease Progression; Drug Therapy, Combination; Female; Follow-Up Studies; Graft Rejection; Graft Survival; Guanidines; Histocompatibility Testing; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Muromonab-CD3; Retrospective Studies; Tacrolimus; Time Factors; Treatment Outcome

2000
Strategy for chronic rejection in recipient of living-related liver transplantation.
    Transplantation proceedings, 2000, Volume: 32, Issue:7

    Topics: Alanine Transaminase; Aspartate Aminotransferases; Child, Preschool; Chronic Disease; Cyclosporine; Drug Therapy, Combination; Family; Female; Graft Rejection; Guanidines; Humans; Immunosuppressive Agents; Liver Transplantation; Living Donors; Lymphocytes; Male; Methylprednisolone; Reoperation; Tacrolimus

2000
Coexpression of CD4 and CD8alpha on rat T-cells in whole blood: a sensitive marker for monitoring T-cell immunosuppressive drugs.
    Journal of immunological methods, 2001, Aug-01, Volume: 254, Issue:1-2

    Topics: Animals; Biomarkers; CD4 Antigens; CD4-Positive T-Lymphocytes; CD8 Antigens; Concanavalin A; Cyclosporine; Everolimus; Fingolimod Hydrochloride; Flow Cytometry; Guanidines; Immunosuppressive Agents; Mitogens; Propylene Glycols; Rats; Rats, Inbred Lew; Sirolimus; Sphingosine; Tacrolimus

2001
Immunosuppressive drugs in islet xenotransplantation: a tool for gaining further insights in the mechanisms of the rejection process.
    Transplantation, 2002, Oct-27, Volume: 74, Issue:8

    Topics: Actins; Animals; Anti-Inflammatory Agents; Antibodies, Heterophile; Cyclosporine; Female; Fetal Tissue Transplantation; Graft Rejection; Guanidines; Immunosuppressive Agents; Interleukins; Islets of Langerhans Transplantation; Isoxazoles; Leflunomide; Male; Prednisolone; Pregnancy; Rats; Rats, Inbred Lew; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Swine; Tacrolimus; Transplantation, Heterologous

2002