guanosine-triphosphate and azauracil

guanosine-triphosphate has been researched along with azauracil* in 1 studies

Other Studies

1 other study(ies) available for guanosine-triphosphate and azauracil

ArticleYear
6-Azauracil inhibition of GTP biosynthesis in Saccharomyces cerevisiae.
    Current genetics, 1992, Volume: 22, Issue:1

    The addition of 6-azauracil to the growth medium causes a strong reduction of the GTP level in the nucleotide pool of Saccharomyces cerevisiae. In-vitro experiments show a strong inhibition of IMP dehydrogenase activity by 6-azaUMP explaining the preceding effect. PPR2 mutants, previously characterized by an increased sensitivity to 6-azauracil compared to the wild-type, are specifically susceptible to the lowering of the GTP pool, and are able to grow in presence of 6-azauracil when guanine is added to the medium.

    Topics: Antimetabolites; Guanosine Triphosphate; Saccharomyces cerevisiae; Uracil

1992