guanidine and thiourea

guanidine has been researched along with thiourea in 43 studies

Research

Studies (43)

Timeframe	Studies, this research(%)	All Research%
pre-1990	10 (23.26)	18.7374
1990's	2 (4.65)	18.2507
2000's	9 (20.93)	29.6817
2010's	18 (41.86)	24.3611
2020's	4 (9.30)	2.80

Authors

Authors	Studies
Durant, GJ; Emmett, JC; Ganellin, CR; Miles, PD; Parsons, ME; Prain, HD; White, GR	1
Borchers, A; Engler, H; Schunack, W; Szelenyi, I	1
Rao, KN	1
Levy, M; Miller, SL; Robertson, MP	1
Houghten, RA; Nefzi, A; Ostresh, JM	1
BEVAN, JA	1
PANT, R	1
LWOFF, A; LWOFF, M	1
ADAMSON, RH	1
LIKAR, M; SCHAUER, P	1
FASTIER, FN	1
Benito, JM; Bootello, P; García Fernandez, JM; Jiménez Blanco, JL; Mellet, CO	1
Fitzmaurice, RJ; Gaggini, F; Kilburn, JD; Srinivasan, N	1
Iguchi, T; Nagasawa, K; Sohtome, Y; Takada, K; Takagi, R; Takemura, N	1
Cao, LH; Liu, YH	1
Bierbach, U; Kucera, GL; Ma, Z; Saluta, G	1
Flemer, S; Madalengoitia, JS; Mamai, A; Wurthmann, A	1
Kubik, S	1
Boschetti, E; Bruschi, M; Candiano, G; Dimuccio, V; Ghiggeri, GM; Gusmano, R; Righetti, PG; Santucci, L	1
FEARON, WR	1
FASTIER, FN; SMIRK, FH	1
Horitsugi, N; Nagasawa, K; Noguchi, K; Shin, B; Sohtome, Y; Takagi, R	1
Ashiq, MI; Dixon, S; Gaggini, F; Kilburn, JD; Tesfatsion, BF	1
Nagasawa, K; Sohtome, Y; Takada, K; Tanaka, S; Yamaguchi, T	1
Kotera, M; Perche, P; Remy, JS	1
Goss, JM; McDougal, NT; Schaus, SE; Ting, A	1
Horitsugi, N; Nagasawa, K; Noguchi, K; Shin, B; Sohtome, Y	1
Nagasawa, K; Sohtome, Y	1
Nagasawa, K; Sohtome, Y; Tanaka, S; Yamaguchi, T	1
Abernethy, G; Higgs, K	1
Averlant-Petit, MC; Benyhe, S; Bojnik, E; Chung, NN; Hernandez, JF; Legrand, B; Martinez, J; Mauchauffée, E; Schiller, PW; Touati-Jallabe, Y	1
Batra, S; Mishra, A	1
Aranha Potter, R; Bowser, AM; Madalengoitia, JS; Yang, Y; Ziller, JW	1
Crich, D; Mandhapati, AR; Rajender, S; Shaw, J	1
Chen, J; Chen, X; Ding, J; Gao, S; Li, Y; Lin, L; Tian, H	1
Botsios, S; Manuelidis, L; Tittman, S	1
Fottner, M; Kapp, TG; Kessler, H	1
Antunes, S; Corre, JP; Douat, C; Goossens, PL; Guichard, G; Mikaty, G	1
Cini, E; De Santis, R; Giannini, G; Manera, F; Manetti, F; Milazzo, FM; Pace, S; Petricci, E; Stasi, MA; Tallarico, C; Vesci, L	1
Balónová, B; Blight, BA; Cinatl, J; Michaelis, M; Serpell, CJ; Thomas, SJ; Wass, MN	1
Caruso, A; Ceramella, J; Iacopetta, D; Longo, P; Mariconda, A; Rosano, C; Saturnino, C; Sinicropi, MS	1
Huczyński, A; Krzywik, J; Maj, E; Mozga, W; Nasulewicz-Goldeman, A; Wietrzyk, J	1
Minneci, M; Misevicius, M; Rozas, I	1

Reviews

5 review(s) available for guanidine and thiourea

Article	Year
Solid phase synthesis of mixture-based acyclic and heterocyclic small molecule combinatorial libraries from resin-bound polyamides. Biopolymers, 2001, Volume: 60, Issue:3 Topics: Combinatorial Chemistry Techniques; Guanidine; Lysine; Models, Chemical; Peptide Biosynthesis; Peptide Library; Peptides; Thiourea	2001
Amino acid containing anion receptors. Chemical Society reviews, 2009, Volume: 38, Issue:2 Topics: Amides; Amino Acids; Anions; Crystallography, X-Ray; Guanidine; Thiourea	2009
Brønsted base catalysts. Topics in current chemistry, 2010, Volume: 291 Topics: Alkaloids; Amines; Catalysis; Guanidine; Imines; Thiourea	2010
Dynamic asymmetric organocatalysis: cooperative effects of weak interactions and conformational flexibility in asymmetric organocatalysts. Chemical communications (Cambridge, England), 2012, Aug-14, Volume: 48, Issue:63 Topics: Catalysis; Entropy; Guanidine; Hydrogen Bonding; Solvents; Stereoisomerism; Thiourea	2012
Thiourea and guanidine derivatives as antimalarial and antimicrobial agents. Current topics in medicinal chemistry, 2013, Volume: 13, Issue:16 Topics: Anti-Bacterial Agents; Antifungal Agents; Antimalarials; Bacteria; Fungi; Guanidine; Microbial Sensitivity Tests; Molecular Structure; Thiourea	2013

Other Studies

38 other study(ies) available for guanidine and thiourea

Article	Year
Cyanoguanidine-thiourea equivalence in the development of the histamine H2-receptor antagonist, cimetidine. Journal of medicinal chemistry, 1977, Volume: 20, Issue:7 Topics: Chemical Phenomena; Chemistry, Physical; Drug Stability; Guanidines; Histamine H2 Antagonists; Imidazoles; Molecular Conformation; Structure-Activity Relationship; Thiourea	1977
[Synthesis and h2-antihistaminic activity of n,n'-bisimidazole-substituted thioureas, cyanoguanidines and 2-nitro-1,1-ethenediamines 10. C: H2-antihistaminics]. Arzneimittel-Forschung, 1982, Volume: 32, Issue:12 Topics: Animals; Chemical Phenomena; Chemistry; Diamines; Gastric Acid; Guanidine; Guanidines; Guinea Pigs; Histamine H2 Antagonists; Imidazoles; In Vitro Techniques; Muscle, Smooth; Thiourea	1982
Denaturation of pteroylpoly-gamma-glutamyl hydrolase from chicken liver by urea, thiourea and guanidine hydrochloride: altered catalytic properties of the enzyme activated by urea. Indian journal of biochemistry & biophysics, 1995, Volume: 32, Issue:1 Topics: Animals; Catalysis; Chickens; Enzyme Activation; gamma-Glutamyl Hydrolase; Guanidine; Guanidines; Liver; Protein Denaturation; Thiourea; Urea	1995
Prebiotic synthesis of diaminopyrimidine and thiocytosine. Journal of molecular evolution, 1996, Volume: 43, Issue:6 Topics: Acetaldehyde; Cytosine; Evolution, Molecular; Guanidine; Hydrogen-Ion Concentration; Hydrolysis; Pyrimidines; Seawater; Solubility; Temperature; Thiourea; Uracil	1996
Action of drugs on intrathoracic sensory nerve endings. A summary. Proceedings of the Western Pharmacology Society, 1962, Volume: 5 Topics: Guanidine; Guanidines; Lobeline; Nerve Endings; Sensory Receptor Cells; Serotonin; Thiourea; Veratrum; Veratrum Alkaloids	1962
[GUANYLATION OF SEVERAL AMINO COMPOUNDS]. Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1964, Volume: 335 Topics: Amines; Amino Acids; Amino Alcohols; Chromatography; Guanidine; Guanidines; Research; Thiourea	1964
[REMARKS ON ISATIN-BETA-THIOSEMICARBAZONE AND ON SEVERAL INHIBITORS OF VIRAL DEVELOPMENT]. Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1964, Feb-10, Volume: 258 Topics: Antiviral Agents; Arginine; Citrulline; Creatine; Creatinine; Enterovirus C, Human; Glutamine; Glycine; Guanidine; Guanidines; Indoles; Isatin; Mutation; Ornithine; Pharmacology; Poliovirus; Thiosemicarbazones; Thiourea; Uracil; Urea	1964
ACTIVITY OF CONGENERS OF HYDROXYUREA AGAINST ADVANCED LEUKEMIA L1210. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1965, Volume: 119 Topics: Animals; Guanidine; Guanidines; Hydrazines; Hydroxylamines; Hydroxyurea; Leukemia L1210; Mice; Pharmacology; Research; Selenium; Selenium Compounds; Thiourea; Urea; Urethane	1965
STUDIES OF SOME SUBSTANCES WITH ANTIVIRAL ACTIVITY. I. THE INHIBITORY EFFECT OF GUANIDINE ON THE GROWTH OF HERPES SIMPLEX VIRUS IN HUMAN EMBRYONIC KIDNEY CELL CULTURES. Pathologia et microbiologia, 1965, Volume: 28 Topics: Antiviral Agents; Arginine; Creatine; Creatinine; Cytopathogenic Effect, Viral; DNA; DNA, Viral; Guanidine; Guanidines; Pharmacology; Research; Simplexvirus; Thiourea; Tissue Culture Techniques; Urea; Virus Cultivation	1965
Effects of some isothiourea and guanidine salts on various preparations of smooth and striped muscle. British journal of pharmacology and chemotherapy, 1949, Volume: 4, Issue:4 Topics: Guanidine; Guanidines; Muscles; Salts; Thiourea	1949
Urea-, thiourea-, and guanidine-linked glycooligomers as phosphate binders in water. The Journal of organic chemistry, 2006, Jul-07, Volume: 71, Issue:14 Topics: Carbohydrate Conformation; Carbohydrate Sequence; Guanidine; Molecular Sequence Data; Oligosaccharides; Phosphates; Stereoisomerism; Thiourea; Urea; Water	2006
Carboxylate binding in polar solvents using pyridylguanidinium salts. Organic & biomolecular chemistry, 2007, Jun-07, Volume: 5, Issue:11 Topics: Carboxylic Acids; Dimethyl Sulfoxide; Guanidine; Salts; Solvents; Thiourea	2007
Organocatalytic asymmetric nitroaldol reaction: cooperative effects of guanidine and thiourea functional groups. Chemistry, an Asian journal, 2007, Sep-03, Volume: 2, Issue:9 Topics: Aldehydes; Catalysis; Chromatography, Liquid; Guanidine; Magnetic Resonance Spectroscopy; Thiourea	2007
Synthesis and bioactivity of novel methyl 6-deoxy-6-(N'-alkyl/aryl-N''-benzothiazol-2-yl)guanidino-alpha-D-glucopyranosides. Carbohydrate research, 2008, Mar-17, Volume: 343, Issue:4 Topics: Alkylation; Animals; Antiviral Agents; Benzothiazoles; Cell Line; Crystallography, X-Ray; Dogs; Glucosides; Guanidine; Influenza B virus; Methylation; Models, Molecular; Molecular Structure; Oxygen; Thiourea	2008
Effect of linkage geometry on biological activity in thiourea- and guanidine-substituted acridines and platinum-acridines. Bioorganic & medicinal chemistry letters, 2008, Jul-01, Volume: 18, Issue:13 Topics: Acridines; Antineoplastic Agents; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Design; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Guanidine; HL-60 Cells; Humans; Inhibitory Concentration 50; Models, Chemical; Platinum; Structure-Activity Relationship; Thiourea; Urea	2008
Strategies for the solid-phase diversification of poly-L-proline-type II peptide mimic scaffolds and peptide scaffolds through guanidinylation. The Journal of organic chemistry, 2008, Oct-03, Volume: 73, Issue:19 Topics: Guanidine; Molecular Mimicry; Peptides; Thiourea	2008
Combinatorial peptide ligand libraries for urine proteome analysis: investigation of different elution systems. Electrophoresis, 2009, Volume: 30, Issue:14 Topics: Adsorption; Adult; Chemical Precipitation; Cholic Acids; Citric Acid; Combinatorial Chemistry Techniques; Electrophoresis, Gel, Two-Dimensional; Female; Guanidine; Humans; Hydrogen-Ion Concentration; Male; Peptide Library; Proteinuria; Proteome; Sodium Dodecyl Sulfate; Thiourea; Urea	2009
The amidine-pentacyanoferrate reaction; a test for guanidines, urea and thiourea. The Analyst, 1946, Volume: 71, Issue:849 Topics: Acids; Amidines; Guanidine; Guanidines; Thiourea; Urea	1946
Circulatory properties of iso-thioureas, guanidines, iso-ureas and amidines. The Journal of pharmacology and experimental therapeutics, 1947, Volume: 89, Issue:3 Topics: Amidines; Blood Pressure; Guanidine; Guanidines; Thiourea; Urea; Vasomotor System	1947
Entropy-controlled catalytic asymmetric 1,4-type Friedel-Crafts reaction of phenols using conformationally flexible guanidine/bisthiourea organocatalyst. Angewandte Chemie (International ed. in English), 2010, Sep-24, Volume: 49, Issue:40 Topics: Catalysis; Entropy; Guanidine; Models, Biological; Molecular Conformation; Phenols; Thiourea	2010
Dimeric self-assembly of pyridyl guanidinium carboxylates in polar solvents. Chemistry (Weinheim an der Bergstrasse, Germany), 2010, Nov-02, Volume: 16, Issue:41 Topics: Calorimetry; Carboxylic Acids; Crystallography, X-Ray; Dimethyl Sulfoxide; Esters; Guanidine; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; Pyridines; Solubility; Solvents; Thiourea; Water	2010
Solvent-dependent enantiodivergent Mannich-type reaction: utilizing a conformationally flexible guanidine/bisthiourea organocatalyst. Angewandte Chemie (International ed. in English), 2010, Nov-22, Volume: 49, Issue:48 Topics: Catalysis; Guanidine; Imines; Molecular Conformation; Solvents; Stereoisomerism; Thiourea	2010
MMT, Npeoc-protected spermine, a valuable synthon for the solid phase synthesis of oligonucleotide oligospermine conjugates via guanidine linkers. Bioorganic & medicinal chemistry, 2011, Mar-15, Volume: 19, Issue:6 Topics: Guanidine; Oligonucleotides; Spermine; Thiourea; Transition Temperature; Trityl Compounds	2011
Linking conformational flexibility and kinetics: catalytic 1,4-type Friedel-Crafts reactions of phenols utilizing 1,3-diamine-tethered guanidine/bisthiourea organocatalysts. Chemistry, an Asian journal, 2011, Sep-05, Volume: 6, Issue:9 Topics: Catalysis; Diamines; Entropy; Guanidine; Kinetics; Phenols; Stereoisomerism; Thiourea	2011
Sequential enantiodivergent organocatalysis: reversibility in enantioswitching controlled by a conformationally flexible guanidine/bisthiourea organocatalyst. Organic & biomolecular chemistry, 2013, May-07, Volume: 11, Issue:17 Topics: Catalysis; Guanidine; Molecular Conformation; Stereoisomerism; Thiourea	2013
Rapid detection of economic adulterants in fresh milk by liquid chromatography-tandem mass spectrometry. Journal of chromatography. A, 2013, May-03, Volume: 1288 Topics: Animals; Chromatography, Liquid; Dairying; Food Contamination; Guanidine; Lithium; Milk; Nitrogen Compounds; Semicarbazides; Tandem Mass Spectrometry; Thiourea; Triazines	2013
Cyclic enkephalins with a diversely substituted guanidine bridge or a thiourea bridge: synthesis, biological and structural evaluations. Journal of medicinal chemistry, 2013, Jul-25, Volume: 56, Issue:14 Topics: Animals; Enkephalins; Guanidine; Humans; Magnetic Resonance Spectroscopy; Peptides, Cyclic; Rats; Receptors, Opioid, mu; Structure-Activity Relationship; Thiourea	2013
Structure-reactivity relationships of zwitterionic 1,3-diaza-Claisen rearrangements. The Journal of organic chemistry, 2013, Dec-06, Volume: 78, Issue:23 Topics: Guanidine; Molecular Structure; Thiourea; Urea	2013
The isothiocyanato moiety: an ideal protecting group for the stereoselective synthesis of sialic acid glycosides and subsequent diversification. Angewandte Chemie (International ed. in English), 2015, Jan-19, Volume: 54, Issue:4 Topics: Deamination; Glycosides; Guanidine; N-Acetylneuraminic Acid; Silanes; Stereoisomerism; Thiocyanates; Thiourea	2015
Guanidinated Thiourea-Decorated Polyethylenimines for Enhanced Membrane Penetration and Efficient siRNA Delivery. Advanced healthcare materials, 2015, Jun-24, Volume: 4, Issue:9 Topics: Cell Membrane; Drug Delivery Systems; Gene Expression Regulation; Guanidine; HeLa Cells; Humans; Polyethyleneimine; RNA, Small Interfering; Thiourea	2015
Rapid chemical decontamination of infectious CJD and scrapie particles parallels treatments known to disrupt microbes and biofilms. Virulence, 2015, Volume: 6, Issue:8 Topics: Amyloid; Animals; Biofilms; Cell Line; Creutzfeldt-Jakob Syndrome; Decontamination; Detergents; Guanidine; Mice; Neurons; Prions; Protein Denaturation; Scrapie; Sodium Dodecyl Sulfate; Surgical Instruments; Thiourea; Urea	2015
Modification and Functionalization of the Guanidine Group by Tailor-made Precursors. Journal of visualized experiments : JoVE, 2017, 04-27, Issue:122 Topics: Acetylation; Alkylation; Chromatography, High Pressure Liquid; Guanidine; Guanidines; Indicators and Reagents; Integrins; Ligands; Parasympathomimetics; Spectrometry, Mass, Electrospray Ionization; Thiourea	2017
Effect of replacing main-chain ureas with thiourea and guanidinium surrogates on the bactericidal activity of membrane active oligourea foldamers. Bioorganic & medicinal chemistry, 2017, 08-15, Volume: 25, Issue:16 Topics: Animals; Anti-Bacterial Agents; Bacillus anthracis; Cell Survival; Dose-Response Relationship, Drug; Guanidine; Mice; Microbial Sensitivity Tests; Molecular Structure; RAW 264.7 Cells; Structure-Activity Relationship; Thiourea; Urea	2017
Hedgehog pathway inhibitors of the acylthiourea and acylguanidine class show antitumor activity on colon cancer in vitro and in vivo. European journal of medicinal chemistry, 2018, Sep-05, Volume: 157 Topics: Animals; Antineoplastic Agents; Cell Line; Cell Proliferation; Cell Survival; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Guanidine; Hedgehog Proteins; Humans; Mice; Mice, Nude; Molecular Structure; Neoplasms, Experimental; NIH 3T3 Cells; Structure-Activity Relationship; Thiourea	2018
Thiourea and Guanidine Compounds and Their Iridium Complexes in Drug-Resistant Cancer Cell Lines: Structure-Activity Relationships and Direct Luminescent Imaging. ChemMedChem, 2020, 02-17, Volume: 15, Issue:4 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Coordination Complexes; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Guanidine; Humans; Iridium; Microscopy, Confocal; Molecular Structure; Neoplasms; Optical Imaging; Structure-Activity Relationship; Thiourea	2020
α-ω Alkenyl-bis-S-Guanidine Thiourea Dihydrobromide Affects HeLa Cell Growth Hampering Tubulin Polymerization. ChemMedChem, 2020, 12-03, Volume: 15, Issue:23 Topics: Antineoplastic Agents; Cell Proliferation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Guanidine; Humans; Molecular Structure; Polymerization; Thiourea; Tubulin; Tubulin Modulators	2020
Synthesis and antiproliferative screening of novel doubly modified colchicines containing urea, thiourea and guanidine moieties. Bioorganic & medicinal chemistry letters, 2021, 09-01, Volume: 47 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colchicine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Guanidine; Humans; Molecular Structure; Structure-Activity Relationship; Thiourea; Urea	2021
Green synthesis of nitroaryl thioureas: Towards an improved preparation of guanidinium DNA binders. Bioorganic & medicinal chemistry letters, 2023, 06-15, Volume: 90 Topics: Guanidine; Guanidines; Thiourea	2023