guanidine and leucine

guanidine has been researched along with leucine in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19903 (13.04)18.7374
1990's4 (17.39)18.2507
2000's16 (69.57)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hodges, RS; Kay, CM; Zhou, NE1
Brems, DN; Havel, HA; Plaisted, SM; Tomich, CS1
elMasry, N; Fersht, AR; Jackson, SE; Johnson, CM; Moracci, M1
Abrahamson, M; Ekiel, I1
Cigic, B; Pain, RH1
Clarke, AR; Lorch, M; Mason, JM; Sessions, RB1
Steensma, E; van den Oever, JM; van Mierlo, CP1
Cho, HY; Hong, BS; Kim, HK; Kim, HY; Shin, DH; Yang, SW; Yoon, HG1
Bennett, AF; Byrne, MP; Chen, J; Holder, JB; Spencer, DS; Stites, WE1
Sode, K; Witarto, AB1
Carlsson, U; Karlsson, M; MÃ¥rtensson, LG1
SETO, Y; TAKADA, A; TOYOSHIMA, S; UEDA, T1
BENGTSSON, S; DINTER, Z1
Andreotti, G; Motta, A1
Kaumaya, PT; Kazanji, M; Lynch, MP; Rawale, SV; Sun, Y; Sundaram, R1
Chen, J; Lu, Z; Sakon, J; Stites, WE1
Anderson, JT; Lee, HY; Lee, KH; Marsh, EN; Slutsky, MM1
Bowler, BE; Kristinsson, R1
Carlsson, U; Karlsson, C; Karlsson, M; MÃ¥rtensson, LG1
Brown, C; Liao, J; Wittung-Stafshede, P1
Disadee, W; Ishikawa, T1
Cheng, C; Lim, BL; Wong, KB1
Freeman, JO; Sherman, JC; Wallhorn, D1

Other Studies

23 other study(ies) available for guanidine and leucine

ArticleYear
Synthetic model proteins: the relative contribution of leucine residues at the nonequivalent positions of the 3-4 hydrophobic repeat to the stability of the two-stranded alpha-helical coiled-coil.
    Biochemistry, 1992, Jun-30, Volume: 31, Issue:25

    Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Circular Dichroism; Computer Simulation; Disulfides; Guanidine; Guanidines; Leucine; Models, Molecular; Molecular Sequence Data; Protein Conformation; Proteins; Repetitive Sequences, Nucleic Acid; Structure-Activity Relationship; Thermodynamics

1992
Stabilization of an associated folding intermediate of bovine growth hormone by site-directed mutagenesis.
    Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:10

    Topics: Animals; Cattle; Circular Dichroism; Escherichia coli; Growth Hormone; Guanidine; Guanidines; Leucine; Lysine; Mutation; Protein Conformation

1988
Effect of cavity-creating mutations in the hydrophobic core of chymotrypsin inhibitor 2.
    Biochemistry, 1993, Oct-26, Volume: 32, Issue:42

    Topics: Amino Acid Sequence; Calorimetry, Differential Scanning; Cloning, Molecular; Escherichia coli; Guanidine; Guanidines; Isoleucine; Leucine; Models, Molecular; Models, Structural; Mutagenesis, Site-Directed; Peptides; Plant Proteins; Protein Denaturation; Protein Structure, Secondary; Recombinant Proteins; Restriction Mapping; Serine Proteinase Inhibitors; Solvents; Spectrometry, Fluorescence; Valine

1993
Folding-related dimerization of human cystatin C.
    The Journal of biological chemistry, 1996, Jan-19, Volume: 271, Issue:3

    Topics: Amino Acid Sequence; Amyloid; Cerebral Hemorrhage; Cloning, Molecular; Cystatin C; Cystatins; Escherichia coli; Genetic Variation; Glutamine; Guanidine; Guanidines; Humans; Hydrogen-Ion Concentration; Leucine; Macromolecular Substances; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Protein Conformation; Protein Denaturation; Protein Folding; Recombinant Proteins; Thermodynamics

1996
Location of the binding site for chloride ion activation of cathepsin C.
    European journal of biochemistry, 1999, Volume: 264, Issue:3

    Topics: Binding Sites; Cathepsin C; Chlorides; Cysteine Proteinase Inhibitors; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Enzyme Activation; Guanidine; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Iodoacetates; Kinetics; Leucine; Models, Biological; Substrate Specificity

1999
Effects of mutations on the thermodynamics of a protein folding reaction: implications for the mechanism of formation of the intermediate and transition states.
    Biochemistry, 2000, Mar-28, Volume: 39, Issue:12

    Topics: Animals; CD2 Antigens; Guanidine; Isoleucine; Kinetics; Leucine; Models, Chemical; Mutagenesis, Site-Directed; Protein Denaturation; Protein Folding; Rats; Recombinant Fusion Proteins; Sulfates; Temperature; Thermodynamics; Valine

2000
Apoflavodoxin (un)folding followed at the residue level by NMR.
    Protein science : a publication of the Protein Society, 2000, Volume: 9, Issue:1

    Topics: Apoproteins; Flavodoxin; Guanidine; Leucine; Magnetic Resonance Spectroscopy; Models, Molecular; Protein Denaturation; Protein Folding

2000
Analysis of essential leucine residue for catalytic activity of novel thermostable chitosanase by site-directed mutagenesis.
    Journal of protein chemistry, 2000, Volume: 19, Issue:7

    Topics: Amino Acid Sequence; Bacillus; Chitin; Chitosan; Conserved Sequence; Drug Stability; Glycoside Hydrolases; Guanidine; Hydrolysis; Kinetics; Leucine; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Denaturation; Protein Structure, Secondary; Sequence Alignment; Temperature

2000
Energetics of side chain packing in staphylococcal nuclease assessed by exchange of valines, isoleucines, and leucines.
    Biochemistry, 2001, Nov-20, Volume: 40, Issue:46

    Topics: Amino Acid Substitution; Enzyme Stability; Guanidine; Isoleucine; Leucine; Methionine; Micrococcal Nuclease; Mutagenesis, Site-Directed; Protein Denaturation; Solvents; Spectrometry, Fluorescence; Thermodynamics; Valine

2001
Increasing the hydrophobic interaction between terminal W-motifs enhances the stability of Salmonella typhimurium sialidase. A general strategy for the stabilization of beta-propeller protein fold.
    Protein engineering, 2001, Volume: 14, Issue:11

    Topics: Alanine; Amino Acid Motifs; Circular Dichroism; Cloning, Molecular; Guanidine; Kinetics; Leucine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Neuraminidase; Protein Conformation; Protein Folding; Protein Structure, Tertiary; Salmonella typhimurium; Thermodynamics

2001
Dramatic stabilization of the native state of human carbonic anhydrase II by an engineered disulfide bond.
    Biochemistry, 2002, Dec-31, Volume: 41, Issue:52

    Topics: Alanine; Amino Acid Substitution; Carbonic Anhydrase II; Circular Dichroism; Cysteine; Disulfides; Enzyme Activation; Enzyme Stability; Genetic Variation; Guanidine; Humans; Leucine; Mutagenesis, Site-Directed; Neisseria gonorrhoeae; Protein Denaturation; Protein Folding

2002
POTENTIATION OF AMINO ACID ANTAGONISTS ON ANTIVIRAL EFFECT OF GUANIDINE.
    The Keio journal of medicine, 1963, Volume: 12

    Topics: Amino Acids; Antiviral Agents; Canavanine; Enterovirus C, Human; Ethionine; Guanidine; Guanidines; Leucine; Poliovirus; Tissue Culture Techniques

1963
SUPPRESSION OF THE INHIBITORY ACTION OF GUANIDINE ON VIRUS MULTIPLICATION BY SOME AMINO ACIDS.
    Virology, 1964, Volume: 24

    Topics: Alanine; Albumins; Amino Acids; Animals; Cattle; Enterovirus; Foot-and-Mouth Disease Virus; Guanidine; Guanidines; Kidney; Leucine; Methionine; Pharmacology; Protein Hydrolysates; Research; Serine; Threonine; Valine

1964
Modulating calcitonin fibrillogenesis: an antiparallel alpha-helical dimer inhibits fibrillation of salmon calcitonin.
    The Journal of biological chemistry, 2004, Feb-20, Volume: 279, Issue:8

    Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Animals; Arginine; Calcitonin; Chromatography, Gel; Circular Dichroism; Dimerization; Dose-Response Relationship, Drug; Guanidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Leucine; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Peptides; Proline; Protein Folding; Protein Structure, Secondary; Salmon; Sequence Homology, Amino Acid

2004
De novo design of peptide immunogens that mimic the coiled coil region of human T-cell leukemia virus type-1 glycoprotein 21 transmembrane subunit for induction of native protein reactive neutralizing antibodies.
    The Journal of biological chemistry, 2004, Jun-04, Volume: 279, Issue:23

    Topics: Amino Acid Sequence; Animals; beta-Galactosidase; Binding, Competitive; Cell Line; Cells, Cultured; Circular Dichroism; COS Cells; Crystallography, X-Ray; Dose-Response Relationship, Drug; Dose-Response Relationship, Immunologic; env Gene Products, Human Immunodeficiency Virus; Enzyme-Linked Immunosorbent Assay; Epitopes; Female; Flow Cytometry; Gene Products, env; Guanidine; HeLa Cells; HTLV-I Antibodies; Human T-lymphotropic virus 1; Humans; Leucine; Mice; Mice, Inbred ICR; Molecular Sequence Data; Peptides; Protein Conformation; Protein Structure, Tertiary; Recombinant Proteins; Retroviridae Proteins, Oncogenic; Temperature; Vaccines, Subunit

2004
Proteins with simplified hydrophobic cores compared to other packing mutants.
    Biophysical chemistry, 2004, Aug-01, Volume: 110, Issue:3

    Topics: Crystallization; Enzyme Stability; Guanidine; Hydrophobic and Hydrophilic Interactions; Leucine; Micrococcal Nuclease; Models, Molecular; Mutation; Protein Conformation; Protein Denaturation; Proteins; Thermodynamics

2004
Fluorous effect in proteins: de novo design and characterization of a four-alpha-helix bundle protein containing hexafluoroleucine.
    Biochemistry, 2004, Dec-28, Volume: 43, Issue:51

    Topics: Circular Dichroism; Guanidine; Leucine; Magnetic Resonance Spectroscopy; Protein Denaturation; Protein Engineering; Protein Structure, Secondary; Staining and Labeling

2004
Communication of stabilizing energy between substructures of a protein.
    Biochemistry, 2005, Feb-22, Volume: 44, Issue:7

    Topics: Amino Acid Substitution; Asparagine; Cytochromes c; Enzyme Stability; Genetic Variation; Guanidine; Hydrogen-Ion Concentration; Isoenzymes; Leucine; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Protein Denaturation; Protein Folding; Saccharomyces cerevisiae Proteins; Temperature; Thermodynamics

2005
Denaturant-assisted formation of a stabilizing disulfide bridge from engineered cysteines in nonideal conformations.
    Biochemistry, 2005, Mar-08, Volume: 44, Issue:9

    Topics: Alanine; Carbonic Anhydrase II; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Entropy; Enzyme Stability; Guanidine; Humans; Leucine; Models, Molecular; Mutagenesis, Site-Directed; Neisseria gonorrhoeae; Protein Conformation; Protein Denaturation; Protein Engineering; Protein Folding; Software; Structure-Activity Relationship

2005
Interface mutation in heptameric co-chaperonin protein 10 destabilizes subunits but not interfaces.
    Archives of biochemistry and biophysics, 2005, Jul-15, Volume: 439, Issue:2

    Topics: Amino Acid Sequence; Amino Acid Substitution; Chaperonin 10; Circular Dichroism; Conserved Sequence; Cross-Linking Reagents; Dimerization; Fluorescence; Glycine; Guanidine; Humans; Leucine; Models, Molecular; Mutation; Protein Conformation; Protein Denaturation; Protein Folding; Protein Subunits; Ultracentrifugation; Urea

2005
Chirality transfer from guanidinium ylides to 3-alkenyl (or 3-alkynyl) aziridine-2-carboxylates and application to the syntheses of (2R,3S)-3-hydroxyleucinate and D-erythro-sphingosine.
    The Journal of organic chemistry, 2005, Nov-11, Volume: 70, Issue:23

    Topics: Aldehydes; Aziridines; Guanidine; Leucine; Sphingosine

2005
The effect of disulfide bond on the conformational stability and catalytic activity of beta-propeller phytase.
    Protein and peptide letters, 2007, Volume: 14, Issue:2

    Topics: 6-Phytase; Amino Acid Sequence; Bacillus subtilis; Catalysis; Circular Dichroism; Disulfides; Guanidine; Leucine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Protein Denaturation; Sequence Alignment; Serine; Temperature

2007
Four-helix bundle cavitein reveals middle leucine as linchpin.
    Biopolymers, 2007, Volume: 88, Issue:5

    Topics: Amides; Amino Acid Sequence; Circular Dichroism; Deuterium Exchange Measurement; Ethers, Cyclic; Guanidine; Hydrophobic and Hydrophilic Interactions; Leucine; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Peptides; Protein Denaturation; Protein Structure, Secondary; Resorcinols; Thermodynamics; Water

2007