Compounds > guanidine

guanidine and crambescidin 800

guanidine has been researched along with crambescidin 800 in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (50.00)29.6817
2010's5 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aron, ZD; Cuevas, C; Overman, LE; Pietraszkiewicz, H; Valeriote, F1
Overman, LE; Rhee, YH1
Black, GP; Concepcion, GP; Diquet, B; Howard-Jones, AG; Ibana, JA; Ireland, CM; Lazaro, JE; Mahmoudi, N; Mangalindan, GC; Mazier, D; Moore, CG; Murphy, PJ; Nitcheu, J; Thomas, DA1
Morris, JC; Nicholas, GM; Phillips, AJ1
Bock, JE; Cotton, N; Crews, P; Davis, RW; Gassner, NC; Giaever, G; Holman, TR; Lokey, RS; Nislow, C; Proctor, MJ; St Onge, RP; Tamble, CM; Tenney, K; White, KN1
Botana, LM; López-Alonso, H; Rubiolo, JA; Ternon, E; Thomas, OP; Vega, FV; Vieytes, MR1
Botana, LM; Cabezas-Sainz, P; Guerra-Varela, J; López, R; Roel, M; Rubiolo, JA; Sánchez, L; Silva, SB; Thomas, OP1
Al-Mourabit, A; Bordignon, A; Campos, PE; De Voogd, N; Frederich, M; Gauvin-Bialecki, A; Illien, B; Marcourt, L; Queiroz, EF; Wolfender, JL1
Denisenko, VA; Dyshlovoy, SA; Makarieva, TN; Popov, RS; Shubina, LK; von Amsberg, G1
Blancafort, P; Flematti, GR; Fromont, J; Shrestha, S; Sorolla, A1

Reviews

1 review(s) available for guanidine and crambescidin 800

ArticleYear
Marine natural products: synthetic aspects.
    Natural product reports, 2007, Volume: 24, Issue:1

    Topics: Alkaloids; Alkanes; Biological Products; Carbamates; Ethers; Guanidine; Guanidines; Lactones; Macrolides; Marine Biology; Molecular Structure; Pyrones; Spiro Compounds

2007

Other Studies

9 other study(ies) available for guanidine and crambescidin 800

ArticleYear
Synthesis and anticancer activity of side chain analogs of the crambescidin alkaloids.
    Bioorganic & medicinal chemistry letters, 2004, Jul-05, Volume: 14, Issue:13

    Topics: Alkaloids; Animals; Antineoplastic Agents; Cell Line, Tumor; Colony-Forming Units Assay; Guanidine; Humans; Rats; Spiro Compounds

2004
Total synthesis of (-)-crambidine and definition of the relative configuration of its unique tetracyclic guanidinium core.
    Journal of the American Chemical Society, 2005, Nov-09, Volume: 127, Issue:44

    Topics: Alkaloids; Guanidine; Spiro Compounds; Stereoisomerism

2005
Antimalarial activity of crambescidin 800 and synthetic analogues against liver and blood stage of Plasmodium sp.
    The Journal of antibiotics, 2006, Volume: 59, Issue:9

    Topics: Animals; Antimalarials; Cells, Cultured; Disease Models, Animal; Erythrocytes; Guanidine; Hepatocytes; Malaria; Mice; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Plasmodium yoelii; Spiro Compounds; Survival Analysis

2006
Accelerating the discovery of biologically active small molecules using a high-throughput yeast halo assay.
    Journal of natural products, 2007, Volume: 70, Issue:3

    Topics: Animals; Antifungal Agents; Combinatorial Chemistry Techniques; Drug Evaluation, Preclinical; Guanidine; Models, Biological; Molecular Structure; Porifera; Saccharomyces cerevisiae; Spiro Compounds

2007
Crambescidin-816 acts as a fungicidal with more potency than crambescidin-800 and -830, inducing cell cycle arrest, increased cell size and apoptosis in Saccharomyces cerevisiae.
    Marine drugs, 2013, Nov-08, Volume: 11, Issue:11

    Topics: Alkaloids; Apoptosis; Cell Cycle Checkpoints; Cell Death; Cell Division; Cell Size; Fungicides, Industrial; G2 Phase; Guanidine; Membrane Potential, Mitochondrial; Saccharomyces cerevisiae; Spiro Compounds

2013
Marine guanidine alkaloids crambescidins inhibit tumor growth and activate intrinsic apoptotic signaling inducing tumor regression in a colorectal carcinoma zebrafish xenograft model.
    Oncotarget, 2016, Dec-13, Volume: 7, Issue:50

    Topics: Alkaloids; Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Adhesion; Cell Cycle Proteins; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Cytoskeleton; Dose-Response Relationship, Drug; G1 Phase Cell Cycle Checkpoints; Guanidine; Hep G2 Cells; HT29 Cells; Humans; Inhibitory Concentration 50; MCF-7 Cells; Membrane Potential, Mitochondrial; Signal Transduction; Spiro Compounds; Time Factors; Tumor Burden; Xenograft Model Antitumor Assays; Zebrafish

2016
Unguiculin A and Ptilomycalins E-H, Antimalarial Guanidine Alkaloids from the Marine Sponge Monanchora unguiculata.
    Journal of natural products, 2017, 05-26, Volume: 80, Issue:5

    Topics: Alkaloids; Animals; Antimalarials; Guanidine; Guanidines; Humans; Inhibitory Concentration 50; KB Cells; Madagascar; Marine Biology; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plasmodium falciparum; Spiro Compounds

2017
Monanchoxymycalin C with anticancer properties, new analogue of crambescidin 800 from the marine sponge
    Natural product research, 2019, Volume: 33, Issue:10

    Topics: Alkaloids; Animals; Antineoplastic Agents; Apoptosis; Drug Screening Assays, Antitumor; Guanidine; HeLa Cells; Humans; Molecular Structure; Porifera; Spiro Compounds

2019
Crambescidin 800, Isolated from the Marine Sponge Monanchora viridis, Induces Cell Cycle Arrest and Apoptosis in Triple-Negative Breast Cancer Cells.
    Marine drugs, 2018, Feb-08, Volume: 16, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Cell Cycle Checkpoints; Cell Line, Tumor; Down-Regulation; Genes, cdc; Guanidine; Humans; Male; Phosphorylation; Porifera; Signal Transduction; Spiro Compounds; Triple Negative Breast Neoplasms

2018