guanidine and alanine

guanidine has been researched along with alanine in 65 studies

Research

Studies (65)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (6.15)	18.7374
1990's	13 (20.00)	18.2507
2000's	39 (60.00)	29.6817
2010's	9 (13.85)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Green, SM; Meeker, AK; Shortle, D	1
Hayashi, S; Ogasahara, K; Sugisaki, Y; Yutani, K	1
Kelley, RF; Richards, FM	1
Ikehara, M; Kanaya, S; Nakamura, H; Oobatake, M	1
Dodge, RW; Laity, JH; Rothwarf, DM; Scheraga, HA; Shimotakahara, S	1
Fothergill-Gilmore, LA; Kelly, SM; Price, NC; White, MF	1
Hahn, U; Landt, O; Mayr, LM; Schmid, FX	1
Manning, JM; Peisach, D; Petsko, G; Pospischil, MA; Ringe, D; Soda, K; Van Ophem, PW	1
Dodge, RW; Scheraga, HA	1
Buehler, FU; Chen, HM; Ford, C; Li, Y; Panda, T; Reilly, PJ	1
Gehrig, P; Gervasoni, P; Plückthun, A	1
Birolo, L; Capitani, G; De Luca, F; Jansonius, JN; Malashkevich, VN; Marino, G; Moretta, A	1
Brown, BM; Sauer, RT	1
Geeves, MA; Holtermann, G; Jacob, M; Perl, D; Reinstein, J; Schindler, T; Schmid, FX	1
Kallenbach, NR; Taudte, S; Xin, H	1
Ferguson, SJ; Tomlinson, EJ	1
Allocati, N; Casalone, E; Di Ilio, C; Masulli, M; Parker, MW; Polekhina, G; Rossjohn, J	1
Ablooglu, AJ; Bishop, SM; Frankel, M; Hubbard, SR; Kohanski, RA; Till, JH	1
Dominguez, MA; Dupureur, CM	1
Sode, K; Witarto, AB	1
Chu, YC; Hua, QX; Jia, W; Katsoyannis, PG; Nakagawa, SH; Weiss, MA; Xu, B	1
Goodman, M; Rew, Y; Zapf, C	1
Bottomley, SP; Cabrita, LD; Whisstock, JC	1
Fairman, R; Ratia, K; Solan, A	1
Kallenbach, NR; Olson, CA; Shi, Z; Sosnick, TR	1
Berndt, KD; Chiaraluce, R; Consalvi, V; Ladenstein, R; Lebbink, JH	1
Carlsson, U; Karlsson, M; Mårtensson, LG	1
Blaber, M; Brych, SR; Kim, J; Lee, J; Logan, TM	1
Clary, WM; Fields, SL; Mackay, DQ; Miller, GT; Standley, MS; Timkovich, R	1
Feng, YM; Guo, ZY; Tang, YH; Wang, S	1
Cheng, H; Golemis, EA; Gould, KL; Roder, H; Zhang, YZ	1
GERATZ, JD	1
BENGTSSON, S; DINTER, Z	1
DUDEL, J	1
Andreotti, G; Motta, A	1
Schmittschmitt, JP; Scholtz, JM	1
Bai, Y; Feng, H; Vu, ND	1
Benzaghou, I; Bisaillon, M; Bougie, I	1
Chan, H; Gjerstad, E; Ho, JD; Janc, JW; Katz, BA; Luong, C; Mackman, RL; McGrath, ME; Mortara, K; Somoza, JR; Sprengeler, PA; Tang, J; Verner, E; Williams, SR; Young, WB	1
Carlsson, U; Karlsson, C; Karlsson, M; Mårtensson, LG	1
Falick, AM; Hu, X; Jones, PR; Kohler, K; Moore, AM; Sparkman, OD; Vierra, C	1
Baddam, S; Bowler, BE	1
Guillén Schlippe, YV; Hedstrom, L	1
Apiyo, D; Wilson, CJ; Wittung-Stafshede, P	1
Muralidhara, BK; Rathinakumar, R; Wittung-Stafshede, P	1
Donadelli, M; Gotte, G; Laurents, DV; Libonati, M; Morbio, M; Vottariello, F	1
Buschauer, A; Dove, S; Ghorai, P; Kraus, A; Preuss, H; Seifert, R	1
Bhardwaj, A; Cingolani, G; Olia, AS; Walker-Kopp, N	1
Ealick, SE; Kurinov, I; Pradeep, L; Scheraga, HA	1
Bolon, D; Deshaies, RJ; Fushman, D; Haririnia, A; Purohit, N; Twarog, MZ; Verma, R	1
Gröhn, F; Klein, K; Rehm, T; Schmuck, C; Stepanenko, V; Würthner, F; Zhang, X	1
Becker, K; Bülow, L; Kvassman, JO; Palmén, LG	1
Amar, M; Brewer, HB; D'Souza, W; Davidson, WS; Demosky, SJ; Neufeld, E; Remaley, AT; Sethi, AA; Stonik, JA; Sviridov, D; Thomas, F	1
Banerjee, R; Fisher, SK; Foster, DJ; Heacock, AM; Vitvitsky, VM	1
Bowler, BE; Kurchan, E; Roder, H; Tzul, FO	1
Afrin, R; Ikai, A; Shiga, K; Takahashi, I	1
Amyes, TL; Barnett, SA; Gerlt, JA; Richard, JP; Wood, BM	1
Draelos, ZD	1
Hongo, K; Iwasa, H; Kawata, Y; Meshitsuka, S; Mizobata, T	1
Ito, T; Kurokawa, T; Mastui, H; Shintani, Y; Tsuji, I	1
Bowler, BE; Khan, MK; Miller, AL	1
Bowler, BE; Khan, MK	1
Cheng, RP; Hsu, HC; Kuo, HT; Kuo, LH; Ting, YT; Wang, WR; Weng, MH; Wu, CH; Yang, PA	1
Armstrong, FA; Brooke, EJ; Carr, SB; Evans, RM; Nomerotskaia, E; Phillips, SE; Sargent, F; Wehlin, SA	1
Chen, J; Ding, B; Gai, F; Mukherjee, D	1

Reviews

1 review(s) available for guanidine and alanine

Article	Year
New reagents, reactions, and peptidomimetics for drug design. Biopolymers, 2001, Volume: 60, Issue:3 Topics: Alanine; Amines; Amino Acids; Drug Design; Enkephalins; Guanidine; Indicators and Reagents; Models, Chemical; Organophosphates; Peptides; Sulfides; Triazines	2001

Other Studies

64 other study(ies) available for guanidine and alanine

Article	Year
Contributions of the polar, uncharged amino acids to the stability of staphylococcal nuclease: evidence for mutational effects on the free energy of the denatured state. Biochemistry, 1992, Jun-30, Volume: 31, Issue:25 Topics: Alanine; Amino Acid Sequence; Amino Acids; Enzyme Stability; Escherichia coli; Glycine; Guanidine; Guanidines; Micrococcal Nuclease; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Denaturation; Thermodynamics	1992
Role of conserved proline residues in stabilizing tryptophan synthase alpha subunit: analysis by mutants with alanine or glycine. Proteins, 1991, Volume: 9, Issue:2 Topics: Alanine; Calorimetry; Circular Dichroism; Enzyme Stability; Glycine; Guanidine; Guanidines; Mutagenesis, Site-Directed; Proline; Protein Conformation; Protein Denaturation; Thermodynamics; Tryptophan Synthase	1991
Replacement of proline-76 with alanine eliminates the slowest kinetic phase in thioredoxin folding. Biochemistry, 1987, Oct-20, Volume: 26, Issue:21 Topics: Alanine; Bacterial Proteins; Escherichia coli; Guanidine; Guanidines; Kinetics; Models, Molecular; Mutation; Proline; Protein Conformation; Protein Denaturation; Thioredoxins	1987
pH-dependent thermostabilization of Escherichia coli ribonuclease HI by histidine to alanine substitutions. Journal of biotechnology, 1993, Volume: 28, Issue:1 Topics: Alanine; Base Sequence; DNA, Bacterial; Enzyme Stability; Escherichia coli; Guanidine; Guanidines; Histidine; Hydrogen-Ion Concentration; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Denaturation; Ribonuclease H; Temperature	1993
Folding pathway of guanidine-denatured disulfide-intact wild-type and mutant bovine pancreatic ribonuclease A. Journal of protein chemistry, 1994, Volume: 13, Issue:4 Topics: Alanine; Animals; Binding Sites; Cattle; Cytidine Monophosphate; Disulfides; Guanidine; Guanidines; Kinetics; Mutagenesis, Site-Directed; Point Mutation; Proline; Protein Denaturation; Protein Folding; Recombinant Proteins; Ribonuclease, Pancreatic; Tyrosine	1994
Substitution of His-181 by alanine in yeast phosphoglycerate mutase leads to cofactor-induced dissociation of the tetrameric structure. The Biochemical journal, 1993, Apr-15, Volume: 291 ( Pt 2) Topics: 2,3-Diphosphoglycerate; Alanine; Bisphosphoglycerate Mutase; Diphosphoglyceric Acids; Enzyme Stability; Guanidine; Guanidines; Histidine; Macromolecular Substances; Protein Denaturation; Saccharomyces cerevisiae; Structure-Activity Relationship	1993
Stability and folding kinetics of ribonuclease T1 are strongly altered by the replacement of cis-proline 39 with alanine. Journal of molecular biology, 1993, Jun-05, Volume: 231, Issue:3 Topics: Alanine; Base Sequence; Circular Dichroism; DNA; Enzyme Stability; Guanidine; Guanidines; Kinetics; Molecular Sequence Data; Proline; Protein Denaturation; Protein Folding; Ribonuclease T1	1993
Catalytic ability and stability of two recombinant mutants of D-amino acid transaminase involved in coenzyme binding. Protein science : a publication of the Protein Society, 1995, Volume: 4, Issue:12 Topics: Alanine; Base Sequence; beta-Alanine; Binding Sites; Catalysis; D-Alanine Transaminase; Enzyme Inhibitors; Enzyme Stability; Guanidine; Guanidines; Hot Temperature; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Denaturation; Pyridoxal Phosphate; Recombinant Proteins; Spectrophotometry; Structure-Activity Relationship; Substrate Specificity; Sulfhydryl Compounds; Transaminases; Urea	1995
Folding and unfolding kinetics of the proline-to-alanine mutants of bovine pancreatic ribonuclease A. Biochemistry, 1996, Feb-06, Volume: 35, Issue:5 Topics: Alanine; Animals; Cattle; Genes, Synthetic; Guanidine; Guanidines; Isomerism; Kinetics; Models, Chemical; Mutation; Pancreas; Proline; Protein Denaturation; Protein Folding; Recombinant Proteins; Ribonuclease, Pancreatic	1996
Effect of replacing helical glycine residues with alanines on reversible and irreversible stability and production of Aspergillus awamori glucoamylase. Protein engineering, 1996, Volume: 9, Issue:6 Topics: Alanine; Aspergillus; Circular Dichroism; Fungal Proteins; Glucan 1,4-alpha-Glucosidase; Glycine; Guanidine; Guanidines; Hot Temperature; Mutagenesis, Site-Directed; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Recombinant Fusion Proteins	1996
Two conformational states of beta-lactamase bound to GroEL: a biophysical characterization. Journal of molecular biology, 1998, Jan-30, Volume: 275, Issue:4 Topics: Alanine; beta-Lactamases; Chaperonin 60; Cysteine; Guanidine; Kinetics; Macromolecular Substances; Mass Spectrometry; Protein Conformation; Protein Denaturation; Protein Folding; Temperature	1998
Functional and structural analysis of cis-proline mutants of Escherichia coli aspartate aminotransferase. Biochemistry, 1999, Jan-19, Volume: 38, Issue:3 Topics: Alanine; Amino Acid Substitution; Aspartate Aminotransferases; Crystallography, X-Ray; Enzyme Activation; Escherichia coli; Guanidine; Hot Temperature; Kinetics; Ligands; Mutagenesis, Site-Directed; Proline; Protein Conformation; Protein Denaturation; Protein Folding; Spectrophotometry; Structure-Activity Relationship	1999
Tolerance of Arc repressor to multiple-alanine substitutions. Proceedings of the National Academy of Sciences of the United States of America, 1999, Mar-02, Volume: 96, Issue:5 Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Circular Dichroism; Dimerization; DNA-Binding Proteins; Guanidine; Hot Temperature; Kinetics; Macromolecular Substances; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Repressor Proteins; Thermodynamics; Urea; Viral Proteins; Viral Regulatory and Accessory Proteins	1999
Microsecond folding of the cold shock protein measured by a pressure-jump technique. Biochemistry, 1999, Mar-09, Volume: 38, Issue:10 Topics: Alanine; Amino Acid Substitution; Bacillus subtilis; Bacterial Proteins; Carrier Proteins; Guanidine; Heat-Shock Proteins; Kinetics; Phenylalanine; Pressure; Protein Folding; Thermodynamics; Time Factors; Viscosity	1999
Alanine mutagenesis of high-mobility-group-protein-1 box B (HMG1-B). The Biochemical journal, 2000, May-01, Volume: 347 Pt 3 Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Animals; Carrier Proteins; Circular Dichroism; DNA; DNA-Binding Proteins; Fluorescence; Guanidine; High Mobility Group Proteins; HMGB1 Protein; Models, Molecular; Molecular Sequence Data; Mutation; Phenylalanine; Protein Binding; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Temperature; Thermodynamics; Tryptophan	2000
Conversion of a c type cytochrome to a b type that spontaneously forms in vitro from apo protein and heme: implications for c type cytochrome biogenesis and folding. Proceedings of the National Academy of Sciences of the United States of America, 2000, May-09, Volume: 97, Issue:10 Topics: Alanine; Amino Acid Substitution; Apoproteins; Cystine; Cytochrome b Group; Cytochrome c Group; Escherichia coli; Genetic Variation; Guanidine; Heme; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Oxidation-Reduction; Protein Denaturation; Protein Folding; Recombinant Proteins; Thermodynamics	2000
Evaluation of the role of two conserved active-site residues in beta class glutathione S-transferases. The Biochemical journal, 2000, Oct-15, Volume: 351 Pt 2 Topics: Alanine; Amino Acid Sequence; Anti-Bacterial Agents; Arginine; Asparagine; Binding Sites; Catalysis; Conserved Sequence; Dose-Response Relationship, Drug; Escherichia coli; Glutathione Transferase; Guanidine; Histidine; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Secondary; Proteus mirabilis; Rifamycins; Spectrometry, Fluorescence; Temperature; Time Factors	2000
Crystallographic and solution studies of an activation loop mutant of the insulin receptor tyrosine kinase: insights into kinase mechanism. The Journal of biological chemistry, 2001, Mar-30, Volume: 276, Issue:13 Topics: Adenosine Triphosphate; Alanine; Amino Acid Motifs; Animals; Aspartic Acid; Binding Sites; Catalysis; Crystallography, X-Ray; Enzyme Activation; Guanidine; Hydrogen Bonding; Kinetics; Models, Molecular; Mutation; Phenylalanine; Phosphorylation; Protein Binding; Protein Conformation; Protein Denaturation; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Receptor, Insulin; Spectrometry, Fluorescence	2001
The PD...(D/E)XK motif in restriction enzymes: a link between function and conformation. Biochemistry, 2001, Jan-16, Volume: 40, Issue:2 Topics: Alanine; Amino Acid Motifs; Binding Sites; Conserved Sequence; Deoxyribonucleases, Type II Site-Specific; Enzyme Stability; Fluorine; Guanidine; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Protein Denaturation; Spectrometry, Fluorescence; Structure-Activity Relationship; Thermodynamics	2001
Increasing the hydrophobic interaction between terminal W-motifs enhances the stability of Salmonella typhimurium sialidase. A general strategy for the stabilization of beta-propeller protein fold. Protein engineering, 2001, Volume: 14, Issue:11 Topics: Alanine; Amino Acid Motifs; Circular Dichroism; Cloning, Molecular; Guanidine; Kinetics; Leucine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Neuraminidase; Protein Conformation; Protein Folding; Protein Structure, Tertiary; Salmonella typhimurium; Thermodynamics	2001
A cavity-forming mutation in insulin induces segmental unfolding of a surrounding alpha-helix. Protein science : a publication of the Protein Society, 2002, Volume: 11, Issue:1 Topics: Alanine; Amino Acid Sequence; Circular Dichroism; Guanidine; Insulin; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Mutation; Peptide Biosynthesis; Peptides; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Temperature; Thermodynamics	2002
Probing the role of the F-helix in serpin stability through a single tryptophan substitution. Biochemistry, 2002, Apr-09, Volume: 41, Issue:14 Topics: Alanine; alpha 1-Antitrypsin; Amino Acid Sequence; Amino Acid Substitution; Drug Stability; Guanidine; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Protein Denaturation; Protein Structure, Secondary; Recombinant Proteins; Serpins; Spectrometry, Fluorescence; Tryptophan	2002
Exploring the role of alanine in the structure of the Lac repressor tetramerization domain, a ferritin-like Alacoil. Journal of molecular biology, 2002, Apr-05, Volume: 317, Issue:4 Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Circular Dichroism; Escherichia coli Proteins; Ferritins; Guanidine; Lac Repressors; Models, Molecular; Molecular Sequence Data; Mutation; Protein Denaturation; Protein Structure, Quaternary; Protein Structure, Tertiary; Repressor Proteins; Sequence Alignment; Sodium Chloride; Temperature; Thermodynamics; Ultracentrifugation; Urea	2002
D/H amide isotope effect in model alpha-helical peptides. Journal of the American Chemical Society, 2002, Nov-27, Volume: 124, Issue:47 Topics: Alanine; Amides; Amino Acid Sequence; Circular Dichroism; Deuterium; DNA-Binding Proteins; Guanidine; Kinetics; Molecular Sequence Data; Peptides; Protein Kinases; Protein Structure, Secondary; Saccharomyces cerevisiae Proteins	2002
Structural and thermodynamic studies on a salt-bridge triad in the NADP-binding domain of glutamate dehydrogenase from Thermotoga maritima: cooperativity and electrostatic contribution to stability. Biochemistry, 2002, Dec-31, Volume: 41, Issue:52 Topics: Alanine; Arginine; Binding Sites; Crystallography, X-Ray; Cysteine; Enzyme Stability; Glutamate Dehydrogenase; Glutamic Acid; Guanidine; Lysine; Mutagenesis, Site-Directed; NADP; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Recombinant Proteins; Salts; Serine; Static Electricity; Structure-Activity Relationship; Thermodynamics; Thermotoga maritima; Urea	2002
Dramatic stabilization of the native state of human carbonic anhydrase II by an engineered disulfide bond. Biochemistry, 2002, Dec-31, Volume: 41, Issue:52 Topics: Alanine; Amino Acid Substitution; Carbonic Anhydrase II; Circular Dichroism; Cysteine; Disulfides; Enzyme Activation; Enzyme Stability; Genetic Variation; Guanidine; Humans; Leucine; Mutagenesis, Site-Directed; Neisseria gonorrhoeae; Protein Denaturation; Protein Folding	2002
Identification of a key structural element for protein folding within beta-hairpin turns. Journal of molecular biology, 2003, May-09, Volume: 328, Issue:4 Topics: Alanine; Amino Acid Sequence; Asparagine; Dose-Response Relationship, Drug; Fibroblast Growth Factor 1; Fibroblast Growth Factors; Glycine; Guanidine; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; Protein Conformation; Protein Folding; Protein Structure, Secondary; Thermodynamics; Time Factors	2003
Expression of Pseudomonas stutzeri Zobell cytochrome c-551 and its H47A variant in Escherichia coli. Protein expression and purification, 2003, Volume: 29, Issue:2 Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Bacterial Proteins; Cytochrome c Group; Enzyme Stability; Escherichia coli; Guanidine; Histidine; Hot Temperature; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Oxidation-Reduction; Pseudomonas; Recombinant Proteins	2003
Contribution of the absolutely conserved B8Gly to the foldability of insulin. Biological chemistry, 2003, Volume: 384, Issue:5 Topics: Alanine; Amino Acid Substitution; Circular Dichroism; Disulfides; Glycine; Guanidine; Insulin; Insulin Secretion; Protein Folding; Recombinant Proteins; Saccharomyces cerevisiae	2003
Structure, stability, and function of hDim1 investigated by NMR, circular dichroism, and mutational analysis. Biochemistry, 2003, Aug-19, Volume: 42, Issue:32 Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Circular Dichroism; DNA Mutational Analysis; Guanidine; Humans; Methyltransferases; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Protein Denaturation; Protein Structure, Secondary; Recombinant Proteins; Saccharomyces cerevisiae Proteins; Sequence Deletion; Structure-Activity Relationship; Thermodynamics	2003
THE INHIBITORY EFFECT OF OMEGA-AMINO ACIDS AND GUANIDINO ACIDS ON THE ACTIVATION OF ALPHA-CHYMOTRYPSINOGEN AND TRYPSINOGEN. Archives of biochemistry and biophysics, 1963, Volume: 102 Topics: Alanine; Amidines; Amino Acids; Aminobutyrates; Aminocaproates; Aminocaproic Acid; Caseins; Chymotrypsin; Chymotrypsinogen; Enzyme Inhibitors; Enzyme Precursors; Guanidine; Guanidines; Levulinic Acids; Pharmacology; Research; Trypsin; Trypsinogen	1963
SUPPRESSION OF THE INHIBITORY ACTION OF GUANIDINE ON VIRUS MULTIPLICATION BY SOME AMINO ACIDS. Virology, 1964, Volume: 24 Topics: Alanine; Albumins; Amino Acids; Animals; Cattle; Enterovirus; Foot-and-Mouth Disease Virus; Guanidine; Guanidines; Kidney; Leucine; Methionine; Pharmacology; Protein Hydrolysates; Research; Serine; Threonine; Valine	1964
PRESYNAPTIC AND POSTSYNAPTIC EFFECTS OF INHIBITORY DRUGS ON THE CRAYFISH NEUROMUSCULAR JUNCTION. Pflugers Archiv fur die gesamte Physiologie des Menschen und der Tiere, 1965, Mar-18, Volume: 283 Topics: Alanine; Animals; Astacoidea; Butyrates; Cell Membrane; Crustacea; Guanidine; Guanidines; Neuromuscular Junction; Pharmacology; Propionates; Research; Synapses	1965
Modulating calcitonin fibrillogenesis: an antiparallel alpha-helical dimer inhibits fibrillation of salmon calcitonin. The Journal of biological chemistry, 2004, Feb-20, Volume: 279, Issue:8 Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Animals; Arginine; Calcitonin; Chromatography, Gel; Circular Dichroism; Dimerization; Dose-Response Relationship, Drug; Guanidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Leucine; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Peptides; Proline; Protein Folding; Protein Structure, Secondary; Salmon; Sequence Homology, Amino Acid	2004
The side chain of aspartic acid 69 dictates the folding mechanism of Bacillus subtilis HPr. Biochemistry, 2004, Feb-10, Volume: 43, Issue:5 Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Bacillus subtilis; Bacterial Proteins; Calorimetry, Differential Scanning; Circular Dichroism; Deuterium Exchange Measurement; Guanidine; Kinetics; Protein Denaturation; Protein Folding; Salts; Sodium Chloride; Solvents; Thermodynamics; Transcription Factors; Urea	2004
The folding pathway of barnase: the rate-limiting transition state and a hidden intermediate under native conditions. Biochemistry, 2004, Mar-30, Volume: 43, Issue:12 Topics: Alanine; Amino Acid Substitution; Bacillus; Bacterial Proteins; Deuterium Exchange Measurement; Glycine; Guanidine; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Nonlinear Dynamics; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Protons; Ribonucleases; Signal Transduction	2004
Effect of metal ion binding on the structural stability of the hepatitis C virus RNA polymerase. The Journal of biological chemistry, 2004, Nov-26, Volume: 279, Issue:48 Topics: Alanine; DNA-Directed RNA Polymerases; Enzyme Stability; Guanidine; Hepacivirus; Metals; Mutation; Protein Denaturation; Spectrometry, Fluorescence; Temperature; Thermodynamics; Urea; Viral Proteins	2004
Dissecting and designing inhibitor selectivity determinants at the S1 site using an artificial Ala190 protease (Ala190 uPA). Journal of molecular biology, 2004, Nov-19, Volume: 344, Issue:2 Topics: Alanine; Amidines; Benzimidazoles; Binding Sites; Crystallography, X-Ray; Drug Design; Guanidine; Humans; Hydrogen Bonding; Indoles; Molecular Structure; Mutagenesis, Site-Directed; Mutation; Protease Inhibitors; Protein Binding; Serine; Structure-Activity Relationship; Substrate Specificity; Thermodynamics; Urokinase-Type Plasminogen Activator; Water	2004
Denaturant-assisted formation of a stabilizing disulfide bridge from engineered cysteines in nonideal conformations. Biochemistry, 2005, Mar-08, Volume: 44, Issue:9 Topics: Alanine; Carbonic Anhydrase II; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Entropy; Enzyme Stability; Guanidine; Humans; Leucine; Models, Molecular; Mutagenesis, Site-Directed; Neisseria gonorrhoeae; Protein Conformation; Protein Denaturation; Protein Engineering; Protein Folding; Software; Structure-Activity Relationship	2005
Egg case protein-1. A new class of silk proteins with fibroin-like properties from the spider Latrodectus hesperus. The Journal of biological chemistry, 2005, Jun-03, Volume: 280, Issue:22 Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Animals; Black Widow Spider; Cloning, Molecular; Codon; Databases as Topic; Disulfides; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Fibroins; Gene Library; Genetic Techniques; Guanidine; Mass Spectrometry; Microscopy, Electron, Scanning; Molecular Sequence Data; Open Reading Frames; Peptides; Protein Binding; Protein Conformation; Protein Denaturation; Protein Isoforms; Reverse Transcriptase Polymerase Chain Reaction; Silk; Silver Staining; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spiders; Trypsin	2005
Thermodynamics and kinetics of formation of the alkaline state of a Lys 79-->Ala/Lys 73-->His variant of iso-1-cytochrome c. Biochemistry, 2005, Nov-15, Volume: 44, Issue:45 Topics: Alanine; Cytochromes c; Guanidine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Mutagenesis, Site-Directed; Proline; Protein Denaturation; Saccharomyces cerevisiae Proteins; Static Electricity; Thermodynamics	2005
Guanidine derivatives rescue the Arg418Ala mutation of Tritrichomonas foetus IMP dehydrogenase. Biochemistry, 2005, Dec-20, Volume: 44, Issue:50 Topics: Alanine; Animals; Arginine; Guanidine; IMP Dehydrogenase; Kinetics; Mutagenesis, Site-Directed; Tritrichomonas foetus	2005
Solvation of the folding-transition state in Pseudomonas aeruginosa azurin is modulated by metal: Solvation of azurin's folding nucleus. Protein science : a publication of the Protein Society, 2006, Volume: 15, Issue:4 Topics: Alanine; Azurin; Cell Nucleus; Guanidine; Metals; Point Mutation; Protein Conformation; Protein Engineering; Protein Folding; Pseudomonas aeruginosa; Solvents; Threonine; Valine; Water; Zinc	2006
Folding of Desulfovibrio desulfuricans flavodoxin is accelerated by cofactor fly-casting. Archives of biochemistry and biophysics, 2006, Jul-01, Volume: 451, Issue:1 Topics: Alanine; Desulfovibrio desulfuricans; Flavin Mononucleotide; Flavodoxin; Guanidine; Kinetics; Ligands; Molecular Structure; Protein Binding; Protein Denaturation; Protein Folding; Tyrosine	2006
Increase of RNase a N-terminus polarity or C-terminus apolarity changes the two domains' propensity to swap and form the two dimeric conformers of the protein. Biochemistry, 2006, Sep-12, Volume: 45, Issue:36 Topics: Alanine; Amino Acid Substitution; Animals; Cattle; Circular Dichroism; Dimerization; Enzyme Stability; Guanidine; Mutagenesis, Site-Directed; Protein Conformation; Protein Folding; Protein Structure, Tertiary; Recombinant Proteins; Ribonuclease, Pancreatic; Serine	2006
Mutations of Cys-17 and Ala-271 in the human histamine H2 receptor determine the species selectivity of guanidine-type agonists and increase constitutive activity. The Journal of pharmacology and experimental therapeutics, 2007, Volume: 321, Issue:3 Topics: Adenylyl Cyclases; Alanine; Animals; Baculoviridae; Cell Line; Cell Membrane; Cysteine; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunits, Gs; Guanidine; Guanosine Triphosphate; Guinea Pigs; Histamine; Histamine Agonists; Histamine H2 Antagonists; Humans; Mutation, Missense; Receptors, Histamine H2; Recombinant Fusion Proteins; Species Specificity; Spodoptera; Transfection	2007
Domain organization and polarity of tail needle GP26 in the portal vertex structure of bacteriophage P22. Journal of molecular biology, 2007, Aug-10, Volume: 371, Issue:2 Topics: Alanine; Bacteriophage P22; Guanidine; Hydrophobic and Hydrophilic Interactions; Mutation; Open Reading Frames; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Transition Temperature; Tryptophan; Viral Proteins	2007
Implementation of a k/k(0) method to identify long-range structure in transition states during conformational folding/unfolding of proteins. Structure (London, England : 1993), 2007, Volume: 15, Issue:10 Topics: Alanine; Animals; Arginine; Cattle; Crystallography, X-Ray; Guanidine; Hydrogen-Ion Concentration; Kinetics; Protein Conformation; Protein Denaturation; Protein Folding; Ribonuclease, Pancreatic; Structure-Activity Relationship; Thermodynamics; Valine	2007
Mutations in the hydrophobic core of ubiquitin differentially affect its recognition by receptor proteins. Journal of molecular biology, 2008, Jan-25, Volume: 375, Issue:4 Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Carrier Proteins; Deuterium; DNA-Binding Proteins; Dose-Response Relationship, Drug; Glutathione Transferase; Glycine; Guanidine; Humans; Hydrogen; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Ligands; Lysine; Models, Molecular; Mutation; Proteasome Endopeptidase Complex; Protein Binding; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Saccharomyces cerevisiae Proteins; Structure-Activity Relationship; Substrate Specificity; Temperature; Thermodynamics; Ubiquitin; Ubiquitination	2008
A new type of soft vesicle-forming molecule: an amino acid derived guanidiniocarbonyl pyrrole carboxylate zwitterion. Organic letters, 2008, Apr-03, Volume: 10, Issue:7 Topics: Alanine; Carboxylic Acids; Guanidine; Models, Molecular; Molecular Structure; Pyrroles; Stereoisomerism	2008
A double role for a strictly conserved serine: further insights into the dUTPase catalytic mechanism. Biochemistry, 2008, Jul-29, Volume: 47, Issue:30 Topics: Alanine; Catalysis; Dimerization; Enzyme Stability; Escherichia coli; Guanidine; Hydrogen Bonding; Hydrolysis; Kinetics; Magnesium; Mutation; Protein Binding; Protein Structure, Secondary; Pyrophosphatases; Serine; Substrate Specificity; Thermodynamics	2008
Asymmetry in the lipid affinity of bihelical amphipathic peptides. A structural determinant for the specificity of ABCA1-dependent cholesterol efflux by peptides. The Journal of biological chemistry, 2008, Nov-21, Volume: 283, Issue:47 Topics: Alanine; Amino Acid Sequence; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Biological Transport; Cholesterol; Circular Dichroism; Erythrocytes; Guanidine; Humans; Lipids; Molecular Sequence Data; Peptides; Phospholipids; Protein Conformation; Time Factors	2008
Muscarinic receptor regulation of osmosensitive taurine transport in human SH-SY5Y neuroblastoma cells. Journal of neurochemistry, 2009, Volume: 108, Issue:2 Topics: Alanine; Antioxidants; Biological Transport; Calcium; Cell Line, Tumor; Cyclopentanes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidine; Humans; Indans; Lysophospholipids; Muscarinic Agonists; Neuroblastoma; Osmolar Concentration; Oxotremorine; Receptors, Muscarinic; Saline Solution, Hypertonic; Sphingosine; Taurine; Thapsigargin; Thrombin; Tritium	2009
Competition between reversible aggregation and loop formation in denatured iso-1-cytochrome c. Biochemistry, 2009, Jan-20, Volume: 48, Issue:2 Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Cytochromes c; Enzyme Stability; Guanidine; Heme; Histidine; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Ligands; Models, Chemical; Molecular Sequence Data; Mutation; Protein Binding; Protein Denaturation; Protein Multimerization; Protein Renaturation; Protein Structure, Secondary; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Temperature	2009
Tensile mechanics of alanine-based helical polypeptide: force spectroscopy versus computer simulations. Biophysical journal, 2009, Volume: 96, Issue:3 Topics: Alanine; Amino Acid Sequence; Biomechanical Phenomena; Circular Dichroism; Computer Simulation; Dose-Response Relationship, Drug; Guanidine; Microscopy, Atomic Force; Models, Molecular; Molecular Sequence Data; Organic Chemicals; Peptides; Protein Denaturation; Protein Structure, Secondary; Sodium Chloride; Solvents; Spectrum Analysis; Tensile Strength	2009
Activation of R235A mutant orotidine 5'-monophosphate decarboxylase by the guanidinium cation: effective molarity of the cationic side chain of Arg-235. Biochemistry, 2010, Feb-09, Volume: 49, Issue:5 Topics: Alanine; Amino Acid Substitution; Arginine; Catalysis; Cations, Monovalent; Enzyme Activation; Enzyme Stability; Fungal Proteins; Guanidine; Orotidine-5'-Phosphate Decarboxylase; Protein Binding; Protein Subunits	2010
Commentary: healthy hair and protein loss. Journal of the American Academy of Dermatology, 2010, Volume: 62, Issue:3 Topics: Alanine; Carbonates; Cystine; Guanidine; Hair; Hair Diseases; Hair Preparations; Lye; Proteins; Scalp Dermatoses; Sulfides	2010
Covalent structural changes in unfolded GroES that lead to amyloid fibril formation detected by NMR: insight into intrinsically disordered proteins. The Journal of biological chemistry, 2011, Jun-17, Volume: 286, Issue:24 Topics: Alanine; Amino Acid Sequence; Amyloid; Asparagine; Aspartic Acid; Chaperonin 10; Escherichia coli; Guanidine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Sequence Data; Mutation; Peptides; Protein Binding; Protein Conformation	2011
L-cysteine-enhanced renaturation of bioactive soluble tumor necrosis factor ligand family member LIGHT from inclusion bodies in Escherichia coli. Protein expression and purification, 2011, Volume: 80, Issue:2 Topics: Alanine; Apoptosis; Biological Assay; Buffers; Cell Line, Tumor; Chromatography, High Pressure Liquid; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Guanidine; Humans; Inclusion Bodies; Plasmids; Protein Renaturation; Recombinant Proteins; Tumor Necrosis Factor Ligand Superfamily Member 14	2011
Tryptophan stabilizes His-heme loops in the denatured state only when it is near a loop end. Biochemistry, 2012, May-01, Volume: 51, Issue:17 Topics: Alanine; Guanidine; Hemeproteins; Histidine; Protein Denaturation; Protein Stability; Protein Structure, Secondary; Tryptophan	2012
Conformational properties of polyglutamine sequences in guanidine hydrochloride solutions. Biophysical journal, 2012, Nov-07, Volume: 103, Issue:9 Topics: Alanine; Amino Acid Sequence; Cytochromes c; Guanidine; Heme; Histidine; Lysine; Molecular Sequence Data; Mutagenesis, Insertional; Peptides; Protein Denaturation; Protein Stability; Protein Structure, Tertiary	2012
Effect of side chain length on intrahelical interactions between carboxylate- and guanidinium-containing amino acids. Amino acids, 2014, Volume: 46, Issue:8 Topics: 2-Aminoadipic Acid; Alanine; Amino Acid Sequence; Amino Acids; Arginine; Aspartic Acid; Carboxylic Acids; Circular Dichroism; Glutamic Acid; Guanidine; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Molecular Conformation; Peptides; Protein Structure, Secondary; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Static Electricity; Thermodynamics	2014
Mechanism of hydrogen activation by [NiFe] hydrogenases. Nature chemical biology, 2016, Volume: 12, Issue:1 Topics: Alanine; Amino Acid Substitution; Asparagine; Crystallography, X-Ray; Escherichia coli Proteins; Guanidine; Hydrogen; Hydrogenase; Iron; Lysine; Mutation; Nickel; Protein Conformation	2016
Do guanidinium and tetrapropylammonium ions specifically interact with aromatic amino acid side chains? Proceedings of the National Academy of Sciences of the United States of America, 2017, 01-31, Volume: 114, Issue:5 Topics: Alanine; Amino Acids, Aromatic; Antimicrobial Cationic Peptides; Circular Dichroism; Guanidine; Hydrophobic and Hydrophilic Interactions; Nitriles; Peptides; Protein Denaturation; Protein Stability; Protein Structure, Secondary; Quaternary Ammonium Compounds; Solvents; Spectrometry, Fluorescence; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared	2017