guanabenz and propranolol

guanabenz has been researched along with propranolol in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19908 (44.44)18.7374
1990's2 (11.11)18.2507
2000's3 (16.67)29.6817
2010's5 (27.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Gubernator, K; Kansy, M; Senner, F1
Faller, B; Wohnsland, F1
Caron, G; Ermondi, G1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Campillo, NE; Guerra, A; Páez, JA1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Soares-da-Silva, P; Villanueva, MM1
Colindres, RE; Strandhoy, JW; Wolff, DW1
Hashimoto, H; Nakashima, M; Sogabe, K1
Alvo, M; Espinoza, AM; Fernandez, V; Marusic, ET1
Cervenka, J; Mosley, C; O'Connor, DT; Slutsky, RA; Taylor, A1
Morgan, TO1
Krakoff, LR1
Insel, PA; Motulsky, HJ; O'Connor, DT1

Trials

1 trial(s) available for guanabenz and propranolol

ArticleYear
Comparative effects of antihypertensive therapy with guanabenz and propranolol on renal vascular resistance and left ventricular mass.
    Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 5

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Body Weight; Double-Blind Method; Guanabenz; Guanidines; Heart; Humans; Hypertension; Male; Middle Aged; Myocardial Contraction; Propranolol; Renal Circulation; Vascular Resistance

1984

Other Studies

17 other study(ies) available for guanabenz and propranolol

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Physicochemical high throughput screening: parallel artificial membrane permeation assay in the description of passive absorption processes.
    Journal of medicinal chemistry, 1998, Mar-26, Volume: 41, Issue:7

    Topics: Absorption; Adsorption; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Permeability; Pharmacokinetics; Spectrophotometry, Ultraviolet

1998
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
    Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6

    Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water

2001
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
The vascular relaxant effects of guanabenz are not mediated by alpha 2-adrenoceptors in rat aortic rings.
    The Journal of pharmacy and pharmacology, 1990, Volume: 42, Issue:3

    Topics: Animals; Aorta, Thoracic; Endothelium, Vascular; Guanabenz; Guanidines; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Serotonin; Vasodilator Agents; Yohimbine

1990
Unmasking sensitive alpha 2-adrenoceptor-mediated renal vasoconstriction in conscious rats.
    The American journal of physiology, 1989, Volume: 257, Issue:6 Pt 2

    Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Dose-Response Relationship, Drug; Guanabenz; Guanidines; Idazoxan; Male; Norepinephrine; Phenylephrine; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Renal Circulation; Vasoconstriction; Yohimbine

1989
Affinities of adrenergic drugs for alpha 2-adrenoceptors in dog saphenous vein in comparison with those in rat brain or human platelets.
    Blood vessels, 1985, Volume: 22, Issue:3

    Topics: Adrenergic alpha-Agonists; Animals; Blood Platelets; Brain; Clonidine; Dogs; Epinephrine; Guanabenz; Humans; Naphazoline; Norepinephrine; Phentolamine; Phenylephrine; Propranolol; Rats; Receptors, Adrenergic, alpha; Saphenous Vein; Tolazoline; Tritium; Yohimbine

1985
Alpha 2-agonists block ADH action in toad bladder and this inhibition is not modified by indomethacin.
    The American journal of physiology, 1988, Volume: 255, Issue:1 Pt 2

    Topics: Adrenergic alpha-Agonists; Animals; Body Water; Bufonidae; Epinephrine; Guanabenz; Indomethacin; Male; Prazosin; Propranolol; Urinary Bladder; Vasopressins; Yohimbine

1988
Comparison of a centrally acting antihypertensive agent and beta-adrenergic blocking agents for the treatment of hypertension.
    Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 5

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Female; Guanabenz; Humans; Hypertension; Male; Middle Aged; Pindolol; Potassium; Propranolol; Pulse; Time Factors

1984
Antihypertensive treatment: cardiovascular risks and monotherapy.
    Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 5

    Topics: Antihypertensive Agents; Benzothiadiazines; Cardiovascular Diseases; Cerebrovascular Disorders; Diuretics; Guanabenz; Humans; Propranolol; Risk; Sodium Chloride Symporter Inhibitors

1984
Platelet alpha 2-adrenergic receptors in treated and untreated essential hypertension.
    Clinical science (London, England : 1979), 1983, Volume: 64, Issue:3

    Topics: Adult; Blood Platelets; Guanabenz; Humans; Hypertension; Male; Middle Aged; Platelet Aggregation; Propranolol; Radioligand Assay; Receptors, Adrenergic; Receptors, Adrenergic, alpha

1983