guanabenz has been researched along with propranolol in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (44.44) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 3 (16.67) | 29.6817 |
| 2010's | 5 (27.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Gubernator, K; Kansy, M; Senner, F | 1 |
| Faller, B; Wohnsland, F | 1 |
| Caron, G; Ermondi, G | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Soares-da-Silva, P; Villanueva, MM | 1 |
| Colindres, RE; Strandhoy, JW; Wolff, DW | 1 |
| Hashimoto, H; Nakashima, M; Sogabe, K | 1 |
| Alvo, M; Espinoza, AM; Fernandez, V; Marusic, ET | 1 |
| Cervenka, J; Mosley, C; O'Connor, DT; Slutsky, RA; Taylor, A | 1 |
| Morgan, TO | 1 |
| Krakoff, LR | 1 |
| Insel, PA; Motulsky, HJ; O'Connor, DT | 1 |
1 trial(s) available for guanabenz and propranolol
| Article | Year |
|---|---|
Comparative effects of antihypertensive therapy with guanabenz and propranolol on renal vascular resistance and left ventricular mass.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Body Weight; Double-Blind Method; Guanabenz; Guanidines; Heart; Humans; Hypertension; Male; Middle Aged; Myocardial Contraction; Propranolol; Renal Circulation; Vascular Resistance | 1984 |
17 other study(ies) available for guanabenz and propranolol
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Physicochemical high throughput screening: parallel artificial membrane permeation assay in the description of passive absorption processes.
Topics: Absorption; Adsorption; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Permeability; Pharmacokinetics; Spectrophotometry, Ultraviolet | 1998 |
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water | 2001 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
The vascular relaxant effects of guanabenz are not mediated by alpha 2-adrenoceptors in rat aortic rings.
Topics: Animals; Aorta, Thoracic; Endothelium, Vascular; Guanabenz; Guanidines; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Serotonin; Vasodilator Agents; Yohimbine | 1990 |
Unmasking sensitive alpha 2-adrenoceptor-mediated renal vasoconstriction in conscious rats.
Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Dose-Response Relationship, Drug; Guanabenz; Guanidines; Idazoxan; Male; Norepinephrine; Phenylephrine; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Renal Circulation; Vasoconstriction; Yohimbine | 1989 |
Affinities of adrenergic drugs for alpha 2-adrenoceptors in dog saphenous vein in comparison with those in rat brain or human platelets.
Topics: Adrenergic alpha-Agonists; Animals; Blood Platelets; Brain; Clonidine; Dogs; Epinephrine; Guanabenz; Humans; Naphazoline; Norepinephrine; Phentolamine; Phenylephrine; Propranolol; Rats; Receptors, Adrenergic, alpha; Saphenous Vein; Tolazoline; Tritium; Yohimbine | 1985 |
Alpha 2-agonists block ADH action in toad bladder and this inhibition is not modified by indomethacin.
Topics: Adrenergic alpha-Agonists; Animals; Body Water; Bufonidae; Epinephrine; Guanabenz; Indomethacin; Male; Prazosin; Propranolol; Urinary Bladder; Vasopressins; Yohimbine | 1988 |
Comparison of a centrally acting antihypertensive agent and beta-adrenergic blocking agents for the treatment of hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Female; Guanabenz; Humans; Hypertension; Male; Middle Aged; Pindolol; Potassium; Propranolol; Pulse; Time Factors | 1984 |
Antihypertensive treatment: cardiovascular risks and monotherapy.
Topics: Antihypertensive Agents; Benzothiadiazines; Cardiovascular Diseases; Cerebrovascular Disorders; Diuretics; Guanabenz; Humans; Propranolol; Risk; Sodium Chloride Symporter Inhibitors | 1984 |
Platelet alpha 2-adrenergic receptors in treated and untreated essential hypertension.
Topics: Adult; Blood Platelets; Guanabenz; Humans; Hypertension; Male; Middle Aged; Platelet Aggregation; Propranolol; Radioligand Assay; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1983 |