guanabenz has been researched along with guanoxabenz in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (35.29) | 18.7374 |
| 1990's | 10 (58.82) | 18.2507 |
| 2000's | 1 (5.88) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Uhlén, S; Wikberg, JE | 1 |
| Dugarin, J; Gorceix, A; Pommier, F | 1 |
| Berridge, TL; Gadie, B; Roach, AG; Tulloch, IF | 1 |
| Dettmar, PW; Lynn, AG; Tulloch, IF | 1 |
| Cavero, I; Doxey, JC; Roach, AG; Strachan, DA | 1 |
| Bourdon, R; Hoffelt, J | 1 |
| Cavellat, M; Chapillon, M; Delhumeau, A; Leboulanger, J | 1 |
| García-Sevilla, JA; Sastre, M | 1 |
| Cloix, JF; Dausse, JP; Le Jossec, M | 1 |
| Clement, B; Demesmaeker, M; Linne, S | 1 |
| Clement, B; Demesmaeker, M | 1 |
| Dambrova, M; Uhlén, S; Welch, CJ; Wikberg, JE | 1 |
| Dambrova, M; Oliver, DW; Tiger, G; Uhlén, S; Wikberg, JE | 1 |
| Dambrova, M; Prusis, P; Uhlén, S; Welch, CJ; Wikberg, JE | 1 |
| Dambrova, M; Uhlén, S; Wikberg, JE | 1 |
| Cirule, H; Dambrova, M; Kalvinsh, I; Meirena, D; Veveris, M; Wikberg, JE | 1 |
| Clement, B; Deters, S; Havemeyer, A; Mau, S | 1 |
17 other study(ies) available for guanabenz and guanoxabenz
| Article | Year |
|---|---|
Delineation of three pharmacological subtypes of alpha 2-adrenoceptor in the rat kidney.
Topics: Animals; Binding, Competitive; Computer Simulation; Dioxanes; Guanabenz; Idazoxan; In Vitro Techniques; Kidney; Male; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1991 |
[Use of presynaptic alpha-mimetics for withdrawal in heroin addicts].
Topics: Adrenergic alpha-Agonists; Adult; Female; Guanabenz; Guanfacine; Guanidines; Heroin Dependence; Hospitalization; Humans; Length of Stay; Male; Phenylacetates; Recurrence; Substance Withdrawal Syndrome; Time Factors | 1985 |
alpha 2-Adrenoceptor agonists induced mydriasis in the rat by an action within the central nervous system.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Atropine; Brain; Dioxins; Epinephrine; Guanabenz; Idazoxan; Injections, Intraventricular; Male; Mydriatics; Physostigmine; Pupil; Rats; Rats, Inbred Strains | 1983 |
Neuropharmacological studies in rodents on the action of RX 781094, a new selective alpha 2-adrenoceptor antagonist.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Cerebral Cortex; Clonidine; Dioxins; Drug Antagonism; Electroencephalography; Guanabenz; Idazoxan; Male; Parietal Lobe; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Sleep; Wakefulness | 1983 |
Sleeping times evoked by alpha adrenoceptor agonists in two-day-old chicks: an experimental model to evaluate full and partial agonists at central alpha-2 adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brain; Brimonidine Tartrate; Chickens; Clonidine; Guanabenz; Guanfacine; Guanidines; Imidazoles; Phenylacetates; Quinoxalines; Receptors, Adrenergic, alpha; Sleep; Thiophenes; Time Factors; Xylazine | 1983 |
[Estimation of guanoxabenz in biological fluids (author's transl)].
Topics: Body Fluids; Chromatography, Gas; Guanabenz; Guanidines; Humans | 1980 |
[Single dose of thiopental or fentanyl. Hemodynamic effects after treatment by an anti-hypertensive drug: guanoxabenz (author's transl)].
Topics: Aged; Antihypertensive Agents; Craniocerebral Trauma; Drug Interactions; Fentanyl; Guanabenz; Guanidines; Hemodynamics; Humans; Hypertension; Middle Aged; Thiopental | 1981 |
Alpha 2-adrenoceptor subtypes identified by [3H]RX821002 binding in the human brain: the agonist guanoxabenz does not discriminate different forms of the predominant alpha 2A subtype.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Binding, Competitive; Brain; Dioxanes; Edetic Acid; Female; Guanabenz; Guanylyl Imidodiphosphate; Humans; Idazoxan; Imidazoles; Indoles; Isoindoles; Isoquinolines; Male; Piperazines; Receptors, Adrenergic, alpha; Sodium Chloride; Tritium | 1994 |
[Evidence for two alpha 2B-adrenoreceptor isoforms in the renal cortex of salt-sensitive and salt resistant Sabra rats. Effect of salt loading].
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Binding, Competitive; Guanabenz; Hypertension; Kidney Cortex; Male; Oxymetazoline; Prazosin; Rats; Receptors, Adrenergic, alpha-2; Sodium, Dietary; Yohimbine | 1995 |
Microsomal catalyzed N-hydroxylation of guanabenz and reduction of the N-hydroxylated metabolite: characterization of the two reactions and genotoxic potential of guanoxabenz.
Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Female; Guanabenz; Humans; Hydroxylation; Inactivation, Metabolic; Male; Mass Spectrometry; Microsomes, Liver; Mutagenicity Tests; NAD; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Rabbits; Spectrophotometry, Ultraviolet; Swine | 1996 |
Formation of guanoxabenz from guanabenz in human liver. A new metabolic marker for CYP1A2.
Topics: Antihypertensive Agents; Biomarkers; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Guanabenz; Humans; Hydroxylation; In Vitro Techniques; Liver; Microsomes, Liver | 1997 |
Identification of an N-hydroxyguanidine reducing activity of xanthine oxidase.
Topics: Animals; Catalysis; Cattle; Guanabenz; Guanidines; Hydroxylamines; Kinetics; Milk; NAD; Oxidation-Reduction; Oxygen; Rats; Xanthine Oxidase | 1998 |
Characterization of the enzymatic activity for biphasic competition by guanoxabenz (1-(2,6-dichlorobenzylidene-amino)-3-hydroxyguanidine) at alpha2-adrenoceptors. I. Description of an enzymatic activity in spleen membranes.
Topics: Animals; Antihypertensive Agents; Binding, Competitive; Cerebral Cortex; Guanabenz; Idazoxan; Magnesium; Male; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Spleen; Xanthine Oxidase | 1998 |
Characterization of the enzymatic activity for biphasic competition by guanoxabenz (1-(2,6-dichlorobenzylidene-amino)-3-hydroxyguanidine) at alpha2-adrenoceptors. II. Description of a xanthine-dependent enzymatic activity in spleen cytosol.
Topics: Allopurinol; Animals; Antihypertensive Agents; Binding, Competitive; Cytosol; Guanabenz; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Spleen; Xanthine; Xanthine Oxidase | 1998 |
Characterization of guanoxabenz reducing activity in rat brain.
Topics: Allopurinol; Animals; Antihypertensive Agents; Binding, Competitive; Cerebral Cortex; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Guanabenz; Male; NAD; NADP; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Synaptic Membranes; Xanthine | 1998 |
Cardioprotective effects of N-hydroxyguanidine PR5 in myocardial ischaemia and reperfusion in rats.
Topics: Animals; Antihypertensive Agents; Arrhythmias, Cardiac; Cardiovascular Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanabenz; Guanidines; Hydroxylamines; Male; Malondialdehyde; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Oxidation-Reduction; Rats; Rats, Wistar; Reperfusion Injury; Xanthine Oxidase | 1999 |
Hepatic, extrahepatic, microsomal, and mitochondrial activation of the N-hydroxylated prodrugs benzamidoxime, guanoxabenz, and Ro 48-3656 ([[1-[(2s)-2-[[4-[(hydroxyamino)iminomethyl]benzoyl]amino]-1-oxopropyl]-4-piperidinyl]oxy]-acetic acid).
Topics: Animals; Benzamidines; Cytochrome P-450 Enzyme System; Cytochrome-B(5) Reductase; Cytochromes b5; Guanabenz; Heterocyclic Compounds; Humans; In Vitro Techniques; Kidney; Kinetics; Liver; Microsomes, Liver; Mitochondria; Oximes; Prodrugs; Swine | 2005 |