guanabenz and guanfacine

guanabenz has been researched along with guanfacine in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199012 (63.16)18.7374
1990's2 (10.53)18.2507
2000's5 (26.32)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Agbaba, D; Filipic, S; Nikolic, K1
Buccafusco, JJ; Li, W1
Elverdin, JC; Kaniucki, MD; Perec, CJ; Stefano, FJ1
Dugarin, J; Gorceix, A; Pommier, F1
Hashimoto, T; Kogure, M; Takeuchi, K1
Kobinger, W1
Blackshear, JL; Fillingim, JM; Strauss, A; Strauss, M1
Brunner, HR; Nussberger, J; Waeber, B1
Bognar, IT; Enero, MA1
Cavero, I; Doxey, JC; Roach, AG; Strachan, DA1
Jarrott, B; Louis, WJ; Summers, RJ1
Glusa, E; Markwardt, F1
Decobert, M; Depoortere, H; Honoré, L1
Shockley, DC; Wade, LH; Williams-Johnson, MM1
Choi, DH; Choi, SH; Chun, BG; Lee, JJ; Park, MS1
Takishita, S; Yamazato, M1
Sica, DA1

Reviews

4 review(s) available for guanabenz and guanfacine

ArticleYear
Rudolf Buchheim lecture. Drugs as tools in research on adrenoceptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 332, Issue:2

    Topics: Angiotensin II; Animals; Azepines; Blood Pressure; Clonidine; Guanabenz; Guanfacine; Guanidines; Heart Rate; Humans; Imidazoles; Methoxamine; Oxymetazoline; Phenylacetates; Prazosin; Propanolamines; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Thiophenes; Xylazine; Yohimbine

1986
Drug effects on the EEG of various species of laboratory animals.
    Neuropsychobiology, 1983, Volume: 9, Issue:4

    Topics: 5-Hydroxytryptophan; Amantadine; Animals; Antihypertensive Agents; Azabicyclo Compounds; Brain; Cats; Chlormethiazole; Clonidine; Diazepam; Electroencephalography; Flunitrazepam; Guanabenz; Guanfacine; Guanidines; Imidazoles; Male; Nitrazepam; Pentobarbital; Phenylacetates; Piperazines; Piracetam; Rats; Sodium Oxybate; Yohimbine

1983
[Centrally-acting antihypertensive drugs].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 3

    Topics: Antihypertensive Agents; Blood Pressure; Clonidine; Guanabenz; Guanfacine; Humans; Hypertension; Imidazoline Receptors; Kidney; Methyldopa; Norepinephrine; Pressoreceptors; Receptors, Drug; Renal Circulation; Sodium; Sympathetic Nervous System; Sympatholytics; Vascular Resistance

2004
Centrally acting antihypertensive agents: an update.
    Journal of clinical hypertension (Greenwich, Conn.), 2007, Volume: 9, Issue:5

    Topics: Adrenergic alpha-Agonists; Antihypertensive Agents; Blood Pressure; Clonidine; Contraindications; Guanabenz; Guanfacine; Humans; Hypertension; Imidazoles; Methyldopa; Oxazoles; Rilmenidine

2007

Trials

1 trial(s) available for guanabenz and guanfacine

ArticleYear
Guanfacine as monotherapy for systemic hypertension.
    The American journal of cardiology, 1986, Mar-28, Volume: 57, Issue:9

    Topics: Adult; Aged; Aldosterone; Cholesterol; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Guanabenz; Guanfacine; Guanidines; Humans; Hypertension; Lipoproteins; Middle Aged; Phenylacetates; Plasma Volume; Random Allocation; Sleep Stages

1986

Other Studies

14 other study(ies) available for guanabenz and guanfacine

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
QSAR study of imidazoline antihypertensive drugs.
    Bioorganic & medicinal chemistry, 2008, Aug-01, Volume: 16, Issue:15

    Topics: Antihypertensive Agents; Binding Sites; Imidazoline Receptors; Imidazolines; Ligands; Models, Molecular; Molecular Structure; Quantitative Structure-Activity Relationship

2008
Effectiveness of alpha 2-adrenergic receptor stimulation in reducing the central toxicity following cholinesterase inhibition.
    Research communications in chemical pathology and pharmacology, 1992, Volume: 75, Issue:1

    Topics: Adrenergic alpha-Agonists; Animals; Behavior, Animal; Cholinesterase Inhibitors; Clonidine; Diazepam; Dose-Response Relationship, Drug; Guanabenz; Guanfacine; Lethal Dose 50; Male; Motor Activity; Pyridostigmine Bromide; Rats; Rats, Inbred Strains; Soman

1992
Effects of guanabenz and guanfacine on postsynaptic alpha 2-adrenoceptors in the rat submaxillary and parotid glands.
    Naunyn-Schmiedeberg's archives of pharmacology, 1985, Volume: 329, Issue:3

    Topics: Adrenergic alpha-Agonists; Animals; Female; Guanabenz; Guanfacine; Guanidines; Parotid Gland; Phenylacetates; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Salivation; Submandibular Gland; Synapses

1985
[Use of presynaptic alpha-mimetics for withdrawal in heroin addicts].
    Annales de medecine interne, 1985, Volume: 136, Issue:5

    Topics: Adrenergic alpha-Agonists; Adult; Female; Guanabenz; Guanfacine; Guanidines; Heroin Dependence; Hospitalization; Humans; Length of Stay; Male; Phenylacetates; Recurrence; Substance Withdrawal Syndrome; Time Factors

1985
Comparison of agonistic and antagonistic actions of guanabenz and guanfacin on alpha 1 and alpha 2-adrenoceptors in isolated smooth muscles.
    Japanese journal of pharmacology, 1987, Volume: 43, Issue:3

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Clonidine; Guanabenz; Guanfacine; Guanidines; In Vitro Techniques; Male; Muscle Denervation; Muscle, Smooth; Muscle, Smooth, Vascular; Phenylacetates; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vas Deferens

1987
Effect of centrally acting antihypertensive drugs on the renin-angiotensin system and vasopressin.
    Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 5

    Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Guanabenz; Guanfacine; Guanidines; Humans; Phenylacetates; Renin; Renin-Angiotensin System; Sodium; Vasopressins

1984
alpha 1-Antagonist activity of the alpha 2-adrenoceptor agonist guanabenz in perfused mesenteric artery of the rat.
    European journal of pharmacology, 1984, Aug-03, Volume: 103, Issue:1-2

    Topics: Animals; Blood Pressure; Clonidine; Female; Guanabenz; Guanfacine; Guanidines; In Vitro Techniques; Male; Mesenteric Arteries; Perfusion; Phenylacetates; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha

1984
Sleeping times evoked by alpha adrenoceptor agonists in two-day-old chicks: an experimental model to evaluate full and partial agonists at central alpha-2 adrenoceptors.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 227, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brain; Brimonidine Tartrate; Chickens; Clonidine; Guanabenz; Guanfacine; Guanidines; Imidazoles; Phenylacetates; Quinoxalines; Receptors, Adrenergic, alpha; Sleep; Thiophenes; Time Factors; Xylazine

1983
Selectivity of a series of clonidine-like drugs for alpha 1 and alpha 2 adrenoceptors in rat brain.
    Neuroscience letters, 1980, Volume: 20, Issue:3

    Topics: Aniline Compounds; Animals; Cerebral Cortex; Clonidine; Guanabenz; Guanfacine; Guanidines; Imidazoles; In Vitro Techniques; Indoramin; Naphazoline; Oxazoles; Phenylacetates; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Structure-Activity Relationship; Thiophenes; Toluidines

1980
Influence of clonidine-like hypotensive drugs on adrenergic platelet reactions.
    Biochemical pharmacology, 1981, Jun-01, Volume: 30, Issue:11

    Topics: Antihypertensive Agents; Blood Platelets; Clonidine; Epinephrine; Guanabenz; Guanfacine; Guanidines; Humans; In Vitro Techniques; Phenylacetates; Platelet Aggregation; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Xylazine

1981
Effects of alpha-2-adrenoceptor agonists on induced diuresis in rats.
    Life sciences, 1993, Volume: 53, Issue:3

    Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Diuresis; Dose-Response Relationship, Drug; Guanabenz; Guanfacine; Male; Prazosin; Rats; Rats, Sprague-Dawley

1993
Imidazoline drugs stabilize lysosomes and inhibit oxidative cytotoxicity in astrocytes.
    Free radical biology & medicine, 2002, Mar-01, Volume: 32, Issue:5

    Topics: Acridine Orange; Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Antineoplastic Agents; Apoptosis; Astrocytes; Cathepsin D; Cell Division; Cell Line; Cerebral Cortex; Cytochrome c Group; Fish Venoms; Guanabenz; Guanfacine; HIV Protease Inhibitors; Idazoxan; Imidazoles; Indoles; Isoindoles; L-Lactate Dehydrogenase; Ligands; Lysosomes; Membrane Potentials; Mitochondria; Naphthoquinones; Neuroglia; Oxidation-Reduction; Pepstatins; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Drug

2002