guanabenz and clonidine

guanabenz has been researched along with clonidine in 106 studies

Research

Studies (106)

Timeframe	Studies, this research(%)	All Research%
pre-1990	62 (58.49)	18.7374
1990's	22 (20.75)	18.2507
2000's	17 (16.04)	29.6817
2010's	4 (3.77)	24.3611
2020's	1 (0.94)	2.80

Authors

Authors	Studies
Hargreaves, RT; Warren, JD; Woodward, DL	1
Andrews, PR; Craik, DJ; Martin, JL	1
Batink, H; de Jonge, A; Thoolen, MJ; Timmermans, PB; van Zwieten, PA; Wilffert, B	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Agbaba, D; Filipic, S; Nikolic, K	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Campillo, NE; Guerra, A; Páez, JA	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Chen, EC; Chien, HC; Giacomini, KM; Huang, Y; Khuri, N; Liang, X; Sali, A; Stecula, A; Yee, SW	1
Orth, H; Ritz, E; Tschöpe, W	1
Asmal, AC; Leary, WP; Williams, PC	1
Accarino, G; Caputi, AP; Giordano, L; Lampa, E; Marmo, E; Rossi, F	1
Di Veroli, C; Petrucci, D	1
Hamilton, CA; Howie, CA; Reid, JL; Yakubu, MA	1
Hsieh, ST; Kubota, Y; Miyajima, T; Nakajima, M; Saito, K; Saito, N; Sano, H; Tsujino, T; Yokoyama, M	1
Kumakura, K; Ohara-Imaizumi, M	1
Cheng, JT; Tsai, LH	1
Buccafusco, JJ; Li, W	1
Downie, JW; Espey, MJ; Gajewski, JB	1
Bhandare, PN; D'Souza, RS; Rataboli, PV	1
Hamilton, CA; Howie, CA; Jardine, E; Reid, JL; Yakubu, MA	1
MacLeod, SM; Manmontri, A	1
Gehr, M; Goldberg, M	1
Kaplan, NM	1
Pandhi, P; Sharma, PL	1
Dunlap, CE; Gould, RJ; Murphy, KM; Snyder, SH; Strandhoy, JW	1
Akimoto, Y; Fujiwara, M; Kurahashi, K; Sono, K	1
Enero, MA; Gutkind, JS	1
Harris, RA; Peris, J; Zahniser, NR	1
Agranat, I; Atlas, D; Cohen, S; Diamant, S; Goldblum, A	1
Hashimoto, H; Nakashima, M; Sogabe, K	1
Cohn, JN; Francis, GS	1
Bernardini, C; Del Tacca, M; Martinotti, E; Soldani, G	1
Kubo, T; Misu, Y; Nagura, J	1
Giles, TD; Quiroz, AC; Sander, GE; Thomas, MG	1
Hashimoto, T; Kogure, M; Takeuchi, K	1
Coote, JH; Lewis, DI; Shi, H	1
Carrier, GO; White, RE	1
DiBona, GF; Koepke, JP	1
Kobinger, W	1
Finberg, JP; Kopin, IJ	1
Chan, JY; Chan, SH	1
Enero, MA; Gutkind, JS; Kazanietz, M	1
Mulry, JT	1
Levadi, DI	1
Lappe, RW; Saslow, BA; Wendt, RL	1
Gehr, M; Goldberg, M; MacCarthy, EP	1
Buckalew, VM; Strandhoy, JW; Wolff, DW	2
Brunner, HR; Nussberger, J; Waeber, B	1
Drayer, JI; Weber, MA	2
Bognar, IT; Enero, MA	1
Smith, CB; Webb, RC; Weiss, RJ	1
Houston, MC	1
Hamilton, CA; Hannah, JA; Reid, JL	2
Dettmar, PW; Lynn, AG; Tulloch, IF	1
Curtis-Prior, PB; Tan, S	1
Cavero, I; Doxey, JC; Roach, AG; Strachan, DA	1
Goldstein, JA	1
Finnerty, FA	1
Jarrott, B; Louis, WJ; Summers, RJ	1
Glusa, E; Markwardt, F	1
Fujie, K; Kubo, T; Misu, Y	1
Fujiwara, M; Muramatsu, I; Nagasaka, Y; Sakakibara, Y	1
Hamilton, CA; Reid, JL	1
Decobert, M; Depoortere, H; Honoré, L	1
Chan, SH; Ong, BT	1
Bonham, AC; Brody, MJ; Portis, LR; Trapani, AJ	1
Hojo, M; Machida, K; Nagasaka, Y; Tatsumi, H; Yoshida, Y	1
Koss, MC	1
Kluyskens, Y; Snoeck, J	1
Deitch, MW; Hare, LE; Walker, BR	1
Inoue, K; Kohno, S; Murata, T; Ohata, K; Sakamoto, H	1
Inoue, K; Kasai, H; Kobayashi, M; Kohno, S; Murata, T; Nagasaka, Y; Ohata, K; Sakamoto, H	1
Kubo, T; Misu, Y	1
Hamilton, CA; Jardine, E; Reid, JL	1
Bisgard, GE; Hedrick, MS; Pizarro, J; Ryan, ML	1
Ernsberger, P; Furin, J; Liedtke, CM	1
Shockley, DC; Wade, LH; Williams-Johnson, MM	1
Edwards, G; Ibbotson, T; Weston, AH	1
Hieble, JP; Kolpak, DC	1
Bisgard, GE; Hedrick, MS; Ryan, ML	1
Colpaert, F; Marien, M; Tellez, S	1
Benedetto, N; Ferrara, C; Folgore, A; Galdiero, F; Molitierno, M	1
Gaynor, PJ; Lookingland, KJ; Tucker, HA; West, CR	1
Ernsberger, P; Kou, YR; Prabhakar, NR	1
Bartolini, A; Galeotti, N; Ghelardini, C; Vinci, MC	1
Kometani, K; Natsume, K	1
Erb, S; Hitchcott, PK; Mueller, D; Rajabi, H; Shaham, Y; Stewart, J	1
Fritz, T; Szabo, B; Wedzony, K	1
Chambless, BD; Oparil, S; Peng, N; Wyss, JM	1
Head, GA	1
Aoki, Y; Araki, T; Chonan, K; Hashimoto, J; Hozawa, A; Imai, Y; Kikuya, M; Matsubara, M; Michimata, M; Nishimura, T; Ohkubo, T; Ugajin, T; Yamaguchi, J	1
Jevtovic-Todorovic, V; Meyenburg, AP; Olney, JW; Wozniak, DF	1
Raasmaja, A; Römer, L; Savola, JM; Wurster, S	1
Takishita, S; Yamazato, M	1
Bartolini, A; Galeotti, N; Ghelardini, C	1
Cardin, JA; Schmidt, MF	1
Bourin, M; Hascoët, M; Massé, F	1
Ernsberger, P; Kossover, R; Previs, SF; Velliquette, RA	1
Sica, DA	1
Kim, SH; Kim, SW; Park, WH; Rhee, KS; Yuan, K	1
Bertolotti, A; Harding, HP; Ron, D; Tsaytler, P	1
Hara, H; Imai, T; Inoue, Y; Takahashi, K; Tanaka, M; Tanida, N	1

Reviews

10 review(s) available for guanabenz and clonidine

Article	Year
Centrally acting sympatholytic agents in the treatment of congestive heart failure. A review of the literature. Drugs, 1990, Volume: 40, Issue:2 Topics: Bromocriptine; Clinical Trials as Topic; Clonidine; Guanabenz; Heart Failure; Humans; Methyldopa; Sympatholytics	1990
The autonomic nervous system in congestive heart failure. Annual review of medicine, 1986, Volume: 37 Topics: Adrenergic beta-Antagonists; Alprazolam; Animals; Autonomic Nervous System; Benzodiazepines; Blood Vessels; Bromocriptine; Cardiovascular Agents; Catecholamines; Clonidine; Cricetinae; Dogs; Dopamine; Guanabenz; Heart; Heart Failure; Hemodynamics; Humans; Myocardium; Norepinephrine; Physical Exertion; Posture; Prognosis; Receptors, Adrenergic; Reflex; Stress, Physiological; Sympathetic Nervous System	1986
Rudolf Buchheim lecture. Drugs as tools in research on adrenoceptors. Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 332, Issue:2 Topics: Angiotensin II; Animals; Azepines; Blood Pressure; Clonidine; Guanabenz; Guanfacine; Guanidines; Heart Rate; Humans; Imidazoles; Methoxamine; Oxymetazoline; Phenylacetates; Prazosin; Propanolamines; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Thiophenes; Xylazine; Yohimbine	1986
Centrally acting antihypertensive agents: a brief overview. Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 5 Topics: Animals; Antihypertensive Agents; Central Nervous System; Clonidine; Guanabenz; Humans; Hypertension; Methyldopa; Reserpine; Sympathetic Nervous System	1984
Abrupt cessation of treatment in hypertension: consideration of clinical features, mechanisms, prevention and management of the discontinuation syndrome. American heart journal, 1981, Volume: 102, Issue:3 Pt 1 Topics: Acute Disease; Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Bethanidine; Blood Pressure; Clonidine; Guanabenz; Heart Failure; Humans; Hypertension; Methyldopa; Myocardial Infarction; Pressoreceptors; Prospective Studies; Substance Withdrawal Syndrome; Syndrome; Time Factors	1981
Central and peripheral blockade of the sympathetic nervous system. The American journal of medicine, 1984, Oct-05, Volume: 77, Issue:4A Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Clonidine; Diuretics; Drug Therapy, Combination; Guanabenz; Humans; Hypertension; Indoramin; Labetalol; Methyldopa; Prazosin; Quinazolines; Reserpine; Sympathetic Nervous System; Sympatholytics	1984
Drug effects on the EEG of various species of laboratory animals. Neuropsychobiology, 1983, Volume: 9, Issue:4 Topics: 5-Hydroxytryptophan; Amantadine; Animals; Antihypertensive Agents; Azabicyclo Compounds; Brain; Cats; Chlormethiazole; Clonidine; Diazepam; Electroencephalography; Flunitrazepam; Guanabenz; Guanfacine; Guanidines; Imidazoles; Male; Nitrazepam; Pentobarbital; Phenylacetates; Piperazines; Piracetam; Rats; Sodium Oxybate; Yohimbine	1983
Therapeutic effects of evening administration of guanabenz and clonidine on morning hypertension. Journal of hypertension, 2003, Volume: 21, Issue:4 Topics: Antihypertensive Agents; Circadian Rhythm; Clonidine; Guanabenz; Humans; Hypertension	2003
[Centrally-acting antihypertensive drugs]. Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 3 Topics: Antihypertensive Agents; Blood Pressure; Clonidine; Guanabenz; Guanfacine; Humans; Hypertension; Imidazoline Receptors; Kidney; Methyldopa; Norepinephrine; Pressoreceptors; Receptors, Drug; Renal Circulation; Sodium; Sympathetic Nervous System; Sympatholytics; Vascular Resistance	2004
Centrally acting antihypertensive agents: an update. Journal of clinical hypertension (Greenwich, Conn.), 2007, Volume: 9, Issue:5 Topics: Adrenergic alpha-Agonists; Antihypertensive Agents; Blood Pressure; Clonidine; Contraindications; Guanabenz; Guanfacine; Humans; Hypertension; Imidazoles; Methyldopa; Oxazoles; Rilmenidine	2007

Trials

7 trial(s) available for guanabenz and clonidine

Article	Year
[Clinical experiences in antihypertensive treatment with guanabenz or clonidine in combination with thiazide]. Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1978, Issue:84 Topics: Adult; Benzothiadiazines; Clinical Trials as Topic; Clonidine; Diuretics; Drug Therapy, Combination; Female; Guanabenz; Guanidines; Humans; Hypertension; Male; Middle Aged; Sodium Chloride Symporter Inhibitors	1978
Evaluation of the efficacy and safety of guanabenz versus clonidine. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1979, Jan-20, Volume: 55, Issue:3 Topics: Adult; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Clonidine; Drug Evaluation; Guanabenz; Guanidines; Humans; Hypertension; Middle Aged; Pulse	1979
[Controlled clinical trial of a new antihypertensive drug: 2,6-dichlorobenzylidene-amino-guanidine acetate]. La Clinica terapeutica, 1976, Feb-29, Volume: 76, Issue:4-3 Topics: Antihypertensive Agents; Clinical Trials as Topic; Clonidine; Guanabenz; Guanidines; Humans; Hypertension	1976
Alpha-adrenergic mechanisms in the pathophysiology of left ventricular heart failure--an analysis of their role in systolic and diastolic dysfunction. Journal of molecular and cellular cardiology, 1986, Volume: 18 Suppl 5 Topics: Adrenergic alpha-Antagonists; Autonomic Nervous System; Central Nervous System; Clinical Trials as Topic; Clonidine; Diastole; Guanabenz; Heart Failure; Heart Ventricles; Humans; Methyldopa; Myocardial Contraction; Receptors, Adrenergic, alpha; Stroke Volume; Systole	1986
Comparison of guanabenz and clonidine in hypertensive patients. Current medical research and opinion, 1980, Volume: 6, Issue:9 Topics: Adult; Blood Pressure; Clinical Trials as Topic; Clonidine; Double-Blind Method; Female; Guanabenz; Guanidines; Humans; Hypertension; Male; Middle Aged; Pulse	1980
Comparative antihypertensive effects of guanabenz and clonidine. The Journal of international medical research, 1982, Volume: 10, Issue:1 Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Body Weight; Clinical Trials as Topic; Clonidine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Guanabenz; Guanidines; Humans; Hydrochlorothiazide; Male; Middle Aged; Pulse; Sleep Stages	1982
Therapeutic effects of evening administration of guanabenz and clonidine on morning hypertension: evaluation using home-based blood pressure measurements. Journal of hypertension, 2003, Volume: 21, Issue:4 Topics: Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Circadian Rhythm; Clonidine; Female; Guanabenz; Heart Rate; Humans; Hypertension; Male; Middle Aged; Treatment Outcome	2003

Other Studies

89 other study(ies) available for guanabenz and clonidine

Article	Year
4-Substituted semicarbazones of mono- and dichlorobenzaldehydes as antihypertensive agents. Journal of medicinal chemistry, 1977, Volume: 20, Issue:11 Topics: Animals; Antihypertensive Agents; Benzaldehydes; Dogs; Hypertension; Rats; Semicarbazones; Structure-Activity Relationship	1977
Functional group contributions to drug-receptor interactions. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship	1984
Quantitative relationships between alpha-adrenergic activity and binding affinity of alpha-adrenoceptor agonists and antagonists. Journal of medicinal chemistry, 1984, Volume: 27, Issue:4 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood Pressure; Brain; Cell Membrane; Clonidine; Kinetics; Prazosin; Quinazolines; Rats; Receptors, Adrenergic, alpha; Structure-Activity Relationship; Vasoconstriction	1984
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
QSAR study of imidazoline antihypertensive drugs. Bioorganic & medicinal chemistry, 2008, Aug-01, Volume: 16, Issue:15 Topics: Antihypertensive Agents; Binding Sites; Imidazoline Receptors; Imidazolines; Ligands; Models, Molecular; Molecular Structure; Quantitative Structure-Activity Relationship	2008
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Discovery of Competitive and Noncompetitive Ligands of the Organic Cation Transporter 1 (OCT1; SLC22A1). Journal of medicinal chemistry, 2017, 04-13, Volume: 60, Issue:7 Topics: Drug Discovery; HEK293 Cells; Humans; Ligands; Molecular Docking Simulation; Organic Cation Transporter 1; Small Molecule Libraries	2017
Experimental analysis of some cardiovascular effects of St 600, clonidine (St 155) and guanabenz (BR 750). Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1977, Volume: 18, Issue:4 Topics: Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Dogs; Guanabenz; Guanidines; Heart Rate; Imidazoles; Rabbits; Rats; Receptors, Adrenergic	1977
Do centrally-acting antihypertensive drugs act at non-adrenergic as well as alpha-2 adrenoceptor sites? Clinical and experimental hypertension. Part A, Theory and practice, 1992, Volume: 14, Issue:5 Topics: Animals; Antihypertensive Agents; Binding Sites; Blood Pressure; Brain; Cisterna Magna; Clonidine; Guanabenz; Heart Rate; Infusion Pumps; Injections; Male; Osmosis; Oxazoles; Rabbits; Radioligand Assay; Receptors, Adrenergic, alpha; Receptors, Cell Surface; Rilmenidine	1992
Expression of Fos-like immunoreactivity by yohimbine and clonidine in the rat brain. European journal of pharmacology, 1992, May-12, Volume: 226, Issue:1 Topics: Animals; Brain; Clonidine; Genes, fos; Guanabenz; Immunoenzyme Techniques; Immunohistochemistry; Male; Neurons; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Yohimbine	1992
Effects of imidazole compounds on catecholamine release in adrenal chromaffin cells. Cellular and molecular neurobiology, 1992, Volume: 12, Issue:3 Topics: Adrenal Medulla; Animals; Catecholamines; Cattle; Cells, Cultured; Clonidine; Guanabenz; Imidazoles; Phenoxybenzamine; Receptors, Adrenergic, alpha; Tolazoline; Yohimbine	1992
Pharmacological characterization of alpha 2-adrenoceptors in isolated jejunum of rabbits. The Chinese journal of physiology, 1992, Volume: 35, Issue:3 Topics: Animals; Clonidine; Colforsin; GTP-Binding Proteins; Guanabenz; In Vitro Techniques; Jejunum; Muscle Contraction; Norepinephrine; Rabbits; Receptors, Adrenergic, alpha	1992
Effectiveness of alpha 2-adrenergic receptor stimulation in reducing the central toxicity following cholinesterase inhibition. Research communications in chemical pathology and pharmacology, 1992, Volume: 75, Issue:1 Topics: Adrenergic alpha-Agonists; Animals; Behavior, Animal; Cholinesterase Inhibitors; Clonidine; Diazepam; Dose-Response Relationship, Drug; Guanabenz; Guanfacine; Lethal Dose 50; Male; Motor Activity; Pyridostigmine Bromide; Rats; Rats, Inbred Strains; Soman	1992
Alpha 2-adrenoceptors not imidazole receptors mediate depression of a sacral spinal reflex in the cat. European journal of pharmacology, 1991, Mar-26, Volume: 195, Issue:2 Topics: Action Potentials; Adrenergic alpha-Antagonists; Animals; Benzazepines; Cats; Clonidine; Female; Guanabenz; Imidazoline Receptors; Male; Receptors, Adrenergic, alpha; Receptors, Drug; Reflex; Spinal Cord; Yohimbine	1991
Dual action of clonidine on ethanol-induced gastric lesions: is the imidazoline-preferring receptor involved? European journal of pharmacology, 1991, Jun-25, Volume: 199, Issue:2 Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Dose-Response Relationship, Drug; Ethanol; Guanabenz; Imidazoline Receptors; Male; Methyldopa; Oxymetazoline; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Drug; Stomach; Yohimbine	1991
Desensitization and down-regulation of brain alpha 2-adrenoceptors by centrally acting antihypertensive drugs. British journal of clinical pharmacology, 1990, Volume: 30 Suppl 1 Topics: Animals; Antihypertensive Agents; Binding, Competitive; Brain; Central Nervous System; Clonidine; Down-Regulation; Guanabenz; Hemodynamics; In Vitro Techniques; Male; Oxazoles; Rabbits; Receptors, Adrenergic, alpha; Rilmenidine; Yohimbine	1990
Effects of alpha-2 agonists on renal function in hypertensive humans. Journal of cardiovascular pharmacology, 1985, Volume: 7 Suppl 8 Topics: Adrenergic alpha-Agonists; Clonidine; Diuresis; Glomerular Filtration Rate; Guanabenz; Humans; Hypertension; Kidney; Methyldopa; Natriuresis	1985
Alpha 2-adrenoceptor agonists in the treatment of hypertension. Journal of cardiovascular pharmacology, 1985, Volume: 7 Suppl 8 Topics: Adrenergic alpha-Agonists; Clonidine; Diuretics; Drug Therapy, Combination; Guanabenz; Humans; Hypertension; Lipids; Methyldopa	1985
Progress in the treatment of essential hypertension. International journal of clinical pharmacology, therapy, and toxicology, 1985, Volume: 23 Suppl 1 Topics: Adrenergic Agents; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Clonidine; Diuretics; Drug Therapy, Combination; Guanabenz; Humans; Hypertension; Methyldopa; Vasodilator Agents	1985
Differential interaction of guanabenz with receptor binding sites in rat brain and kidney. Research communications in chemical pathology and pharmacology, 1989, Volume: 66, Issue:1 Topics: Animals; Binding, Competitive; Brain; Clonidine; Dihydroalprenolol; Guanabenz; Guanidines; Guanine Nucleotides; In Vitro Techniques; Isoproterenol; Kidney; Kinetics; Male; Membranes; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Temperature	1989
Effects of specific alpha-adrenoceptive agents on extraneuronal uptake (uptake2) of isoproterenol in perfused rat heart. Life sciences, 1989, Volume: 44, Issue:14 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Guanabenz; Isoproterenol; Male; Methoxamine; Myocardium; Neurons; Phenylephrine; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Sulfonamides; Tropolone	1989
Different pharmacological interaction of clonidine and guanabenz with antidepressive drugs. Clinical and experimental hypertension. Part A, Theory and practice, 1987, Volume: 9, Issue:10 Topics: Animals; Antidepressive Agents; Blood Pressure; Cardiovascular System; Clonidine; Drug Interactions; Female; Guanabenz; Guanidines; Heart Rate; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha	1987
Modulation of gamma-[3H]aminobutyric acid release from rat cortical slices by alpha 2-adrenoceptors. Neuroscience letters, 1987, Oct-05, Volume: 80, Issue:3 Topics: Animals; Calcium; Clonidine; gamma-Aminobutyric Acid; Guanabenz; In Vitro Techniques; Male; Norepinephrine; Occipital Lobe; Parietal Lobe; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine	1987
Beta-adrenergic activity and conformation of the antihypertensive specific alpha 2-agonist drug, guanabenz. Biochemical pharmacology, 1985, Feb-15, Volume: 34, Issue:4 Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Animals; Binding, Competitive; Clonidine; Cyclic AMP; Erythrocytes; Guanabenz; Guanidines; In Vitro Techniques; Iodocyanopindolol; Models, Molecular; Molecular Conformation; Pindolol; Quantum Theory; Receptors, Adrenergic, beta; Turkeys; X-Ray Diffraction	1985
Affinities of adrenergic drugs for alpha 2-adrenoceptors in dog saphenous vein in comparison with those in rat brain or human platelets. Blood vessels, 1985, Volume: 22, Issue:3 Topics: Adrenergic alpha-Agonists; Animals; Blood Platelets; Brain; Clonidine; Dogs; Epinephrine; Guanabenz; Humans; Naphazoline; Norepinephrine; Phentolamine; Phenylephrine; Propranolol; Rats; Receptors, Adrenergic, alpha; Saphenous Vein; Tolazoline; Tritium; Yohimbine	1985
The effects of alpha-2 agonists and antagonists on gastric acid secretion. Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 281, Issue:1 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dose-Response Relationship, Drug; Female; Gastric Juice; Guanabenz; Guinea Pigs; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Tolazoline; Xylazine; Yohimbine	1986
Pharmacological characterization of spinal alpha adrenoceptors related to blood pressure control in rats. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:1 Topics: Adrenergic alpha-Antagonists; Animals; Azepines; Blood Pressure; Brain Stem; Clonidine; Dopamine; Guanabenz; Hydroxydopamines; Injections, Spinal; Male; Norepinephrine; Oxidopamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Spinal Cord; Yohimbine	1987
Comparison of agonistic and antagonistic actions of guanabenz and guanfacin on alpha 1 and alpha 2-adrenoceptors in isolated smooth muscles. Japanese journal of pharmacology, 1987, Volume: 43, Issue:3 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Clonidine; Guanabenz; Guanfacine; Guanidines; In Vitro Techniques; Male; Muscle Denervation; Muscle, Smooth; Muscle, Smooth, Vascular; Phenylacetates; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vas Deferens	1987
Effects of activating spinal alpha-adrenoreceptors on sympathetic nerve activity in the rat. Journal of the autonomic nervous system, 1988, Volume: 23, Issue:1 Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Epinephrine; Guanabenz; Injections, Spinal; Kidney; Male; Methoxamine; Neurons; Norepinephrine; Rats; Receptors, Adrenergic, alpha; Spinal Cord; Sympathetic Nervous System	1988
Enhanced vascular alpha-adrenergic neuroeffector system in diabetes: importance of calcium. The American journal of physiology, 1988, Volume: 255, Issue:5 Pt 2 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Clonidine; Diabetes Mellitus, Experimental; Electric Stimulation; Endothelium, Vascular; Guanabenz; Male; Mesenteric Arteries; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine	1988
Central adrenergic receptor control of renal function in conscious hypertensive rats. Hypertension (Dallas, Tex. : 1979), 1986, Volume: 8, Issue:2 Topics: Animals; Blood Pressure; Clonidine; Guanabenz; Hypertension; Kidney; Male; Natriuresis; Phenoxybenzamine; Prazosin; Rats; Rats, Inbred SHR; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Urodynamics; Yohimbine	1986
Chronic clonidine treatment produces desensitisation of post- but not presynaptic alpha 2-adrenoceptors. European journal of pharmacology, 1987, Jun-12, Volume: 138, Issue:1 Topics: Animals; Blood Pressure; Body Weight; Catecholamines; Clonidine; Decerebrate State; Dose-Response Relationship, Drug; Electric Stimulation; Guanabenz; Heart Rate; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Synapses	1987
Interactions between guanabenz and clonidine in their antinociceptive effects in the rat. Experimental neurology, 1987, Volume: 96, Issue:1 Topics: Analgesics; Animals; Clonidine; Drug Interactions; Guanabenz; Guanidines; Male; Pain Measurement; Rats; Rats, Inbred Strains; Reaction Time	1987
Cardiovascular effects of alpha-adrenergic drugs: differences between clonidine and guanabenz. Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 332, Issue:4 Topics: Animals; Blood Pressure; Brain; Clonidine; Decerebrate State; Dopamine; Female; Guanabenz; Guanidines; Heart Rate; Norepinephrine; Rats; Rats, Inbred Strains	1986
Guanabenz therapy for opiate withdrawal. Drug intelligence & clinical pharmacy, 1985, Volume: 19, Issue:1 Topics: Adult; Clonidine; Codeine; Guanabenz; Guanidines; Humans; Male; Substance Withdrawal Syndrome	1985
Use of guanabenz in methadone withdrawal. The American journal of psychiatry, 1985, Volume: 142, Issue:9 Topics: Adult; Clonidine; Female; Guanabenz; Guanidines; Humans; Methadone; Opioid-Related Disorders; Substance Withdrawal Syndrome	1985
Effects of nifedipine on the hypotensive actions of alpha 2-agonists in conscious spontaneously hypertensive rats. Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 5 Topics: Administration, Oral; Adrenergic alpha-Agonists; Animals; Blood Pressure; Clonidine; Drug Interactions; Guanabenz; Hypertension; Injections, Intravenous; Injections, Intraventricular; Male; Nifedipine; Rats; Rats, Inbred SHR	1984
Natriuretic and water diuretic effects of central alpha 2-adrenoceptor agonists. Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 5 Topics: Adrenergic alpha-Agonists; Blood Pressure; Blood Volume; Clonidine; Diuresis; Guanabenz; Homeostasis; Humans; Methyldopa; Natriuresis; Sodium; Water-Electrolyte Balance	1984
Renal alpha 1- and alpha 2-adrenoceptor mediated vasoconstriction in dogs: comparison of phenylephrine, clonidine, and guanabenz. Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 5 Topics: Animals; Calcium; Clonidine; Denervation; Dogs; Drug Interactions; Female; Guanabenz; Guanidines; Kidney; Male; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Renal Circulation; Vasoconstriction; Verapamil; Yohimbine	1984
Effect of centrally acting antihypertensive drugs on the renin-angiotensin system and vasopressin. Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 5 Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Guanabenz; Guanfacine; Guanidines; Humans; Phenylacetates; Renin; Renin-Angiotensin System; Sodium; Vasopressins	1984
alpha 1-Antagonist activity of the alpha 2-adrenoceptor agonist guanabenz in perfused mesenteric artery of the rat. European journal of pharmacology, 1984, Aug-03, Volume: 103, Issue:1-2 Topics: Animals; Blood Pressure; Clonidine; Female; Guanabenz; Guanfacine; Guanidines; In Vitro Techniques; Male; Mesenteric Arteries; Perfusion; Phenylacetates; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha	1984
Comparison of alpha 2 adrenoreceptors on arterial smooth muscle and brain homogenates from spontaneously hypertensive and Wistar-Kyoto normotensive rats. Journal of hypertension, 1984, Volume: 2, Issue:3 Topics: Animals; Arteries; Brain; Clonidine; Epinephrine; Guanabenz; In Vitro Techniques; Male; Membranes; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Yohimbine	1984
Renal alpha 1- and alpha 2-adrenoceptor mediated vasoconstriction in dogs. Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1984, Volume: 2, Issue:3 Topics: Animals; Calcium; Clonidine; Dogs; Dose-Response Relationship, Drug; Guanabenz; Kidney; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Renal Circulation; Vasoconstriction; Verapamil; Yohimbine	1984
Peripheral alpha 1- and alpha 2-adrenoreceptor mechanisms in blood pressure control. Chest, 1983, Volume: 83, Issue:2 Suppl Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Blood Pressure; Clonidine; Dioxins; Guanabenz; Idazoxan; Male; Muscle, Smooth, Vascular; Norepinephrine; Phenoxybenzamine; Phentolamine; Prazosin; Pressoreceptors; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Synapses; Vascular Resistance	1983
RX781094, a new potent alpha 2 adrenoceptor antagonist. In vivo and in vitro studies in the rabbit. Naunyn-Schmiedeberg's archives of pharmacology, 1983, Volume: 322, Issue:3 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Brain; Clonidine; Dioxins; Dose-Response Relationship, Drug; Drug Interactions; Guanabenz; Heart Rate; Idazoxan; Male; Rabbits	1983
Neuropharmacological studies in rodents on the action of RX 781094, a new selective alpha 2-adrenoceptor antagonist. Neuropharmacology, 1983, Volume: 22, Issue:6 Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Cerebral Cortex; Clonidine; Dioxins; Drug Antagonism; Electroencephalography; Guanabenz; Idazoxan; Male; Parietal Lobe; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Sleep; Wakefulness	1983
Regulation of adipose tissue metabolism via adrenergic mechanisms: actions of alpha-adrenoceptor agonists on lipolysis in hamster fat cells. International journal of obesity, 1983, Volume: 7, Issue:4 Topics: Adipose Tissue; Adrenergic alpha-Agonists; Animals; Clonidine; Cricetinae; Guanabenz; Imidazoles; Lipolysis; Male; Phenylephrine	1983
Sleeping times evoked by alpha adrenoceptor agonists in two-day-old chicks: an experimental model to evaluate full and partial agonists at central alpha-2 adrenoceptors. The Journal of pharmacology and experimental therapeutics, 1983, Volume: 227, Issue:2 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brain; Brimonidine Tartrate; Chickens; Clonidine; Guanabenz; Guanfacine; Guanidines; Imidazoles; Phenylacetates; Quinoxalines; Receptors, Adrenergic, alpha; Sleep; Thiophenes; Time Factors; Xylazine	1983
Alpha-2 agonists as analgesics. The Journal of clinical psychiatry, 1984, Volume: 45, Issue:1 Topics: Adrenergic alpha-Agonists; Clonidine; Endorphins; Guanabenz; Humans; Pain	1984
Office management of hypertension. Comprehensive therapy, 1984, Volume: 10, Issue:2 Topics: Adrenergic beta-Antagonists; Aged; Ambulatory Care; Antihypertensive Agents; Benzothiadiazines; Captopril; Clonidine; Diuretics; Guanabenz; Humans; Hydralazine; Hypertension; Methyldopa; Middle Aged; Prazosin; Reserpine; Sodium Chloride Symporter Inhibitors	1984
Selectivity of a series of clonidine-like drugs for alpha 1 and alpha 2 adrenoceptors in rat brain. Neuroscience letters, 1980, Volume: 20, Issue:3 Topics: Aniline Compounds; Animals; Cerebral Cortex; Clonidine; Guanabenz; Guanfacine; Guanidines; Imidazoles; In Vitro Techniques; Indoramin; Naphazoline; Oxazoles; Phenylacetates; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Structure-Activity Relationship; Thiophenes; Toluidines	1980
Influence of clonidine-like hypotensive drugs on adrenergic platelet reactions. Biochemical pharmacology, 1981, Jun-01, Volume: 30, Issue:11 Topics: Antihypertensive Agents; Blood Platelets; Clonidine; Epinephrine; Guanabenz; Guanfacine; Guanidines; Humans; In Vitro Techniques; Phenylacetates; Platelet Aggregation; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Xylazine	1981
Presynaptic dual inhibitory actions of guanabenz on adrenergic transmission. European journal of pharmacology, 1982, Jan-22, Volume: 77, Issue:2-3 Topics: Animals; Clonidine; Electric Stimulation; Female; Guanabenz; Guanethidine; Guanidines; Heart Rate; Male; Muscle Contraction; Nerve Endings; Rabbits; Stimulation, Chemical; Sympathetic Nervous System; Synaptic Transmission	1982
Effects of guanabenz on the adrenergic mechanism in rabbit arterial strips. Japanese journal of pharmacology, 1981, Volume: 31, Issue:6 Topics: Animals; Arteries; Clonidine; Electric Stimulation; Female; Guanabenz; Guanethidine; Guanidines; In Vitro Techniques; Male; Norepinephrine; Phentolamine; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Tritium; Tyramine; Vasoconstriction	1981
The effects of intravenous 6-hydroxydopamine on peripheral alpha-adrenoreceptors. Journal of autonomic pharmacology, 1982, Volume: 2, Issue:1 Topics: Animals; Blood Pressure; Clonidine; Guanabenz; Heart Rate; Hemodynamics; Hydroxydopamines; Male; Norepinephrine; Phentolamine; Phenylephrine; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Tissue Distribution	1982
Interactions between guanabenz and clonidine in their cardiovascular effects in the rat. Experimental neurology, 1984, Volume: 86, Issue:1 Topics: Animals; Blood Pressure; Cardiovascular System; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Guanabenz; Guanidines; Heart Rate; Rats; Rats, Inbred Strains	1984
Studies on the mechanism of the central antihypertensive effect of guanabenz and clonidine. Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1984, Volume: 2, Issue:3 Topics: Animals; Blood Pressure; Cerebral Ventricles; Clonidine; Dose-Response Relationship, Drug; Guanabenz; Guanidines; Heart Rate; Injections, Intraventricular; Male; Pressoreceptors; Rats; Rats, Inbred Strains; Sinoatrial Node	1984
[Effects of guanabenz on the cardiovascular system, in comparison with clonidine and guanethidine]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1983, Volume: 81, Issue:1 Topics: Animals; Antihypertensive Agents; Autonomic Agents; Cardiovascular System; Cats; Clonidine; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Female; Guanabenz; Guanethidine; Guanidines; Hemodynamics; Injections, Intra-Arterial; Male; Myocardial Contraction; Rabbits; Rats; Vagus Nerve; Vasoconstriction	1983
Analysis of CNS sympatho-inhibition produced by guanabenz. European journal of pharmacology, 1983, May-20, Volume: 90, Issue:1 Topics: Animals; Blood Pressure; Cats; Central Nervous System; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; Female; Ganglia, Sympathetic; Guanabenz; Guanidines; Heart Rate; Hypothalamus; Male; Peripheral Nerves; Sympathetic Nervous System; Yohimbine	1983
[Studies on the antinociceptive activity of guanabenz, with particular reference to clonidine and morphine (author's transl)]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1982, Feb-01, Volume: 79, Issue:2 Topics: Analgesics; Animals; Clonidine; Dose-Response Relationship, Drug; Female; Guanabenz; Guanidines; Guinea Pigs; Ileum; In Vitro Techniques; Locomotion; Male; Mice; Morphine; Muscle Contraction; Muscle, Smooth; Rats; Rats, Inbred Strains; Yohimbine	1982
[Pharmacological studies of guanabenz: effects of the central nervous system]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1982, Volume: 80, Issue:6 Topics: Animals; Anticonvulsants; Avoidance Learning; Body Temperature; Brain; Chlorpromazine; Clonidine; Diazepam; Guanabenz; Guanidines; Male; Mice; Muscle Relaxants, Central; Psychomotor Performance; Rabbits; Rats; Rats, Inbred Strains; Sleep	1982
Central and peripheral cardiovascular responses of rats to guanabenz and clonidine. Japanese journal of pharmacology, 1982, Volume: 32, Issue:5 Topics: Animals; Blood Pressure; Catheterization; Clonidine; Guanabenz; Guanidines; Heart Rate; Male; Nervous System Physiological Phenomena; Rats; Rats, Inbred Strains	1982
Down-regulation of imidazoline sites in rabbit kidney. European journal of pharmacology, 1993, Oct-12, Volume: 243, Issue:1 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Down-Regulation; Guanabenz; Idazoxan; Imidazoline Receptors; Kidney; Male; Oxazoles; Rabbits; Receptors, Drug; Rilmenidine	1993
Modulation of respiratory rhythm by alpha 2-adrenoceptors in awake and anesthetized goats. Journal of applied physiology (Bethesda, Md. : 1985), 1994, Volume: 77, Issue:2 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Antagonists; Anesthesia; Animals; Benzazepines; Blood Gas Analysis; Blood Pressure; Carotid Body; Clonidine; Goats; Guanabenz; Heart Rate; Hypercapnia; Phrenic Nerve; Respiration, Artificial; Respiratory Mechanics; Vagotomy	1994
Alpha 2-adrenergic, but not imidazole, agonists activate NaCl cotransport in rabbit tracheal epithelial cells. The American journal of physiology, 1993, Volume: 264, Issue:3 Pt 1 Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Carrier Proteins; Cells, Cultured; Chloride-Bicarbonate Antiporters; Clonidine; Colforsin; Cyclic AMP; Drug Interactions; Epithelial Cells; Epithelium; Guanabenz; Imidazoles; Imidazoline Receptors; Iodine Radioisotopes; Isoproterenol; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Receptors, Drug; Second Messenger Systems; Sodium Chloride Symporters; Symporters; Thromboxane-A Synthase; Trachea	1993
Effects of alpha-2-adrenoceptor agonists on induced diuresis in rats. Life sciences, 1993, Volume: 53, Issue:3 Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Diuresis; Dose-Response Relationship, Drug; Guanabenz; Guanfacine; Male; Prazosin; Rats; Rats, Sprague-Dawley	1993
Antagonism of levcromakalim by imidazoline- and guanidine-derivatives in rat portal vein: involvement of the delayed rectifier. British journal of pharmacology, 1993, Volume: 110, Issue:4 Topics: Animals; Antazoline; Benzopyrans; Clonidine; Cromakalim; Glyburide; Guanabenz; Imidazoline Receptors; Male; Phentolamine; Portal Vein; Potassium Channels; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Drug	1993
Mediation of the hypotensive action of systemic clonidine in the rat by alpha 2-adrenoceptors. British journal of pharmacology, 1993, Volume: 110, Issue:4 Topics: Animals; Benzazepines; Blood Pressure; Clonidine; Guanabenz; Imidazoline Receptors; Male; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Drug	1993
Recurrent laryngeal nerve activation by alpha 2 adrenergic agonists in goats. Respiration physiology, 1995, Volume: 101, Issue:2 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Apnea; Benzazepines; Carbon Dioxide; Chemoreceptor Cells; Clonidine; Goats; Guanabenz; Partial Pressure; Phrenic Nerve; Recurrent Laryngeal Nerve; Respiration; Sodium Cyanide	1995
Acetylcholine release in the rat prefrontal cortex in vivo: modulation by alpha 2-adrenoceptor agonists and antagonists. Journal of neurochemistry, 1997, Volume: 68, Issue:2 Topics: Acetylcholine; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Guanabenz; Idazoxan; Imidazoles; Male; Microdialysis; Piperoxan; Prefrontal Cortex; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley	1997
Effects of alpha-adrenergic agonists on Toxoplasma gondii replication in human umbilical vein endothelial cells. Pathologie-biologie, 1997, Volume: 45, Issue:1 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cells, Cultured; Clonidine; Endothelium, Vascular; Guanabenz; Humans; In Vitro Techniques; Methoxamine; Nitrogen Dioxide; Toxoplasma; Umbilical Veins; Yohimbine	1997
Regulation of growth hormone-releasing hormone and somatostatin from perifused, bovine hypothalamic slices. I. Alpha 2-adrenergic receptor regulation. Domestic animal endocrinology, 1997, Volume: 14, Issue:5 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cattle; Clonidine; Growth Hormone-Releasing Hormone; Guanabenz; Homeostasis; Hypothalamus; Idazoxan; In Vitro Techniques; Potassium Chloride; Receptors, Adrenergic, alpha-2; Somatostatin	1997
Carotid body I1-imidazoline receptors: binding, visualization and modulatory function. Respiration physiology, 1998, Volume: 112, Issue:3 Topics: Adrenergic alpha-Agonists; Affinity Labels; Animals; Autoradiography; Carotid Body; Cats; Clonidine; Guanabenz; Hypoxia; Imidazoline Receptors; Iodine Radioisotopes; Membranes; Rabbits; Radioligand Assay; Receptors, Adrenergic, alpha-2; Receptors, Drug	1998
Role of potassium channels in the antinociception induced by agonists of alpha2-adrenoceptors. British journal of pharmacology, 1999, Volume: 126, Issue:5 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Analgesia; Animals; Apamin; Clonidine; Guanabenz; Kv1.1 Potassium Channel; Male; Mice; Pain Measurement; Pertussis Toxin; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Psychomotor Performance; Sulfonylurea Compounds; Virulence Factors, Bordetella	1999
Desynchronization of carbachol-induced theta-like activities by alpha-adrenergic agents in guinea pig hippocampal slices. Neuroscience research, 1999, Volume: 33, Issue:3 Topics: Adenine; Adenylyl Cyclase Inhibitors; Adrenergic alpha-Agonists; Animals; Carbachol; Clonidine; Dentate Gyrus; Enzyme Inhibitors; Epinephrine; Excitatory Postsynaptic Potentials; Guanabenz; Guinea Pigs; Hippocampus; In Vitro Techniques; Neurons; Oscillometry; Synaptic Transmission; Theta Rhythm	1999
Alpha-2 adrenergic receptor agonists block stress-induced reinstatement of cocaine seeking. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2000, Volume: 23, Issue:2 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Catheterization; Clonidine; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Electric Stimulation; Guanabenz; Infusions, Intravenous; Injections, Intraperitoneal; Male; Microdialysis; Narcotic Antagonists; Norepinephrine; Rats; Rats, Long-Evans; Self Administration; Stress, Physiological; Sucrose	2000
Effects of imidazoline antihypertensive drugs on sympathetic tone and noradrenaline release in the prefrontal cortex. British journal of pharmacology, 2001, Volume: 134, Issue:2 Topics: Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Guanabenz; Heart Rate; Imidazoles; Male; Microdialysis; Norepinephrine; Oxazoles; Prefrontal Cortex; Rats; Rats, Wistar; Rilmenidine; Sympathetic Nervous System	2001
Alpha2A-adrenergic receptors mediate sympathoinhibitory responses to atrial natriuretic peptide in the mouse anterior hypothalamic nucleus. Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:3 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Anterior Hypothalamic Nucleus; Atrial Natriuretic Factor; Blood Pressure; Clonidine; Guanabenz; Heart Rate; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neural Inhibition; Point Mutation; Receptors, Adrenergic, alpha-2; Sympathetic Nervous System	2003
Anti-parkinsonian agents procyclidine and ethopropazine alleviate thermal hyperalgesia in neuropathic rats. Neuropharmacology, 2003, Volume: 44, Issue:6 Topics: Adrenergic alpha-Agonists; Animals; Antiparkinson Agents; Clonidine; Constriction, Pathologic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Guanabenz; Hyperalgesia; Ligation; Pain Measurement; Peripheral Nervous System Diseases; Phenothiazines; Procyclidine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, N-Methyl-D-Aspartate; Sciatic Nerve	2003
Identification and characterization of the imidazoline I2b-binding sites in the hamster brown adipose tissue as a study model for imidazoline receptors. Archives of physiology and biochemistry, 2003, Volume: 111, Issue:2 Topics: Adipose Tissue, Brown; Amiloride; Animals; Binding Sites; Binding, Competitive; Cell Line, Tumor; Clonidine; Culture Techniques; Dose-Response Relationship, Drug; Guanabenz; Humans; Idazoxan; Imidazoles; Imidazoline Receptors; Liver; Mammary Neoplasms, Animal; Mice; Protein Binding; Rats; Receptors, Drug; Species Specificity; Yohimbine	2003
Alpha-2 agonist-induced memory impairment is mediated by the alpha-2A-adrenoceptor subtype. Behavioural brain research, 2004, Aug-31, Volume: 153, Issue:2 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Avoidance Learning; Brain; Clonidine; Dose-Response Relationship, Drug; Electroshock; Fear; Guanabenz; Imidazoles; Indoles; Injections, Intraperitoneal; Isoindoles; Male; Mental Recall; Mice; Motor Activity; Motor Skills; Reaction Time; Receptors, Adrenergic, alpha-2; Yohimbine	2004
Noradrenergic inputs mediate state dependence of auditory responses in the avian song system. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Sep-01, Volume: 24, Issue:35 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adrenergic Fibers; Animals; Arousal; Auditory Perception; Clonidine; Dose-Response Relationship, Drug; Finches; Guanabenz; Idazoxan; Imidazoles; Isoproterenol; Male; Norepinephrine; Oxathiins; Phenylephrine; Propanolamines; Prosencephalon; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta-2; Vocalization, Animal; Yohimbine	2004
alpha2-Adrenergic agonists antagonise the anxiolytic-like effect of antidepressants in the four-plate test in mice. Behavioural brain research, 2005, Oct-14, Volume: 164, Issue:1 Topics: Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Citalopram; Clonidine; Cyclohexanols; Cyclopropanes; Dose-Response Relationship, Drug; Drug Antagonism; Guanabenz; Male; Mice; Milnacipran; Motor Activity; Paroxetine; Punishment; Selective Serotonin Reuptake Inhibitors; Statistics, Nonparametric; Venlafaxine Hydrochloride	2005
Lipid-lowering actions of imidazoline antihypertensive agents in metabolic syndrome X. Naunyn-Schmiedeberg's archives of pharmacology, 2006, Volume: 372, Issue:4 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Cell Membrane; Cholesterol; Clonidine; Disease Models, Animal; Female; Guanabenz; Hyperlipidemias; Imidazoles; Imidazoline Receptors; Liver; Male; Metabolic Syndrome; Oxazoles; Rats; Rats, Inbred SHR; Receptors, Drug; Rilmenidine; Triglycerides	2006
Different response of ANP secretion to adrenoceptor stimulation in renal hypertensive rat atria. Peptides, 2008, Volume: 29, Issue:7 Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Atrial Natriuretic Factor; Clonidine; Cyclic AMP; Dose-Response Relationship, Drug; Guanabenz; Heart Atria; Hypertension, Renal; Imidazoles; Isoproterenol; Male; Phenylephrine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; RNA, Messenger; Time Factors	2008
Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis. Science (New York, N.Y.), 2011, Apr-01, Volume: 332, Issue:6025 Topics: Adrenergic alpha-2 Receptor Agonists; Catalytic Domain; Cell Line; Clonidine; Endoplasmic Reticulum; Enzyme Inhibitors; Eukaryotic Initiation Factor-2; Guanabenz; HeLa Cells; Homeostasis; Humans; Molecular Chaperones; Phosphorylation; Protein Biosynthesis; Protein Folding; Protein Phosphatase 1; Protein Subunits; Proteins; Stress, Physiological; Tunicamycin	2011
Guanabenz and Clonidine, α2-Adrenergic Receptor Agonists, Inhibit Choroidal Neovascularization. Current neurovascular research, 2021, Volume: 18, Issue:1 Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Cell Movement; Cell Proliferation; Choroidal Neovascularization; Clonidine; Disease Models, Animal; Endothelial Cells; Guanabenz; Humans; Male; Mice; Retina; Treatment Outcome; Vascular Endothelial Growth Factor A	2021