Page last updated: 2024-09-03

guan-fu base a and quinidine

guan-fu base a has been researched along with quinidine in 2 studies

Compound Research Comparison

Studies
(guan-fu base a)
Trials
(guan-fu base a)
Recent Studies (post-2010)
(guan-fu base a)
Studies
(quinidine)
Trials
(quinidine)
Recent Studies (post-2010) (quinidine)
362106,608387594

Protein Interaction Comparison

ProteinTaxonomyguan-fu base a (IC50)quinidine (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)6.4
CholinesteraseHomo sapiens (human)1.23
ATP-dependent translocase ABCB1Mus musculus (house mouse)10
ATP-dependent translocase ABCB1Homo sapiens (human)3.32
Cytochrome P450 2D26Rattus norvegicus (Norway rat)2.8
Cytochrome P450 2D6Homo sapiens (human)0.3532
Potassium voltage-gated channel subfamily A member 5Homo sapiens (human)7.3
CholinesteraseEquus caballus (horse)7.37
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)6.4
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.7882
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)6.4
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)6.4
Sodium channel protein type 5 subunit alphaHomo sapiens (human)6.9
Potassium voltage-gated channel subfamily D member 2Rattus norvegicus (Norway rat)2.2

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gong, GQ; Liu, JH; Su, L; Wang, YQ1
A, J; Ho, RJ; Liu, J; Liu, K; Peng, Y; Qi, H; Shang, L; Sun, J; Sun, Y; Wang, G; Wu, H; Xiao, Y; Zhang, F; Zhang, X; Zhong, Y; Zhu, J1

Other Studies

2 other study(ies) available for guan-fu base a and quinidine

ArticleYear
[Guanfu base A inhibit the post-infarction ventricular arrhythmias in dogs].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1994, Volume: 29, Issue:2

    Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dogs; Female; Heterocyclic Compounds, 4 or More Rings; Ligation; Male; Myocardial Infarction; Quinidine

1994
Guanfu base A, an antiarrhythmic alkaloid of Aconitum coreanum, Is a CYP2D6 inhibitor of human, monkey, and dog isoforms.
    Drug metabolism and disposition: the biological fate of chemicals, 2015, Volume: 43, Issue:5

    Topics: Aconitum; Alkaloids; Animals; Anti-Arrhythmia Agents; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Dextromethorphan; Dextrorphan; Dogs; Drug Interactions; Female; Haplorhini; Heterocyclic Compounds, 4 or More Rings; Humans; Male; Mice; Microsomes, Liver; Protein Isoforms; Quinidine; Rats

2015