Page last updated: 2024-09-03

guan-fu base a and dextromethorphan

guan-fu base a has been researched along with dextromethorphan in 1 studies

Compound Research Comparison

Studies
(guan-fu base a)
Trials
(guan-fu base a)
Recent Studies (post-2010)
(guan-fu base a)
Studies
(dextromethorphan)
Trials
(dextromethorphan)
Recent Studies (post-2010) (dextromethorphan)
362102,020342593

Protein Interaction Comparison

ProteinTaxonomyguan-fu base a (IC50)dextromethorphan (IC50)
Sodium channel protein type 1 subunit alphaRattus norvegicus (Norway rat)1.3
Sodium channel protein type 2 subunit alphaRattus norvegicus (Norway rat)1.3
Sodium channel protein type 3 subunit alphaRattus norvegicus (Norway rat)1.3
Cytochrome P450 2D26Rattus norvegicus (Norway rat)5.6
Cytochrome P450 2D6Homo sapiens (human)2.1768
Sodium-dependent serotonin transporterHomo sapiens (human)0.0027
Sigma non-opioid intracellular receptor 1Cavia porcellus (domestic guinea pig)0.1236

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
A, J; Ho, RJ; Liu, J; Liu, K; Peng, Y; Qi, H; Shang, L; Sun, J; Sun, Y; Wang, G; Wu, H; Xiao, Y; Zhang, F; Zhang, X; Zhong, Y; Zhu, J1

Other Studies

1 other study(ies) available for guan-fu base a and dextromethorphan

ArticleYear
Guanfu base A, an antiarrhythmic alkaloid of Aconitum coreanum, Is a CYP2D6 inhibitor of human, monkey, and dog isoforms.
    Drug metabolism and disposition: the biological fate of chemicals, 2015, Volume: 43, Issue:5

    Topics: Aconitum; Alkaloids; Animals; Anti-Arrhythmia Agents; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Dextromethorphan; Dextrorphan; Dogs; Drug Interactions; Female; Haplorhini; Heterocyclic Compounds, 4 or More Rings; Humans; Male; Mice; Microsomes, Liver; Protein Isoforms; Quinidine; Rats

2015