guajavarin has been researched along with isoquercitrin* in 2 studies
2 other study(ies) available for guajavarin and isoquercitrin
Article | Year |
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One new diphenylmethane glycoside from the leaves of Psidium guajava L.
To investigate the chemical constituents of Psidium guajava L, the EtOH/H(2)O extract of the fresh leaves was subjected to various chromatography. One diphenylmethane, one benzophenone, and eight flavonoids were isolated and elucidated as 2,6-dihydroxy-3-formaldehyde-5-methyl-4-O-(6″-O-galloyl-β-D-glucopyranosyl)-diphenylmethane (1), 2,6-dihydroxy-3,5-dimethyl-4-O-(6″-O-galloyl-β-D-glucopyranosyl)-benzophenone (2), kaempferol (3), quercetin (4), quercitrin (5), isoquercitrin (6), guaijaverin (7), avicularin (8), hyperoside (9), reynoutrin (10) by spectroscopic methods, including 1D and 2D NMR and HR-ESI-MS spectrometry as well as by comparison with published data. Compounds 5 and 10 are obtained from P. guajava for the first time, and compound 1 is a new diphenylmethane compound. Topics: Benzhydryl Compounds; Benzophenones; Flavonoids; Gallic Acid; Glucosides; Glycosides; Magnetic Resonance Spectroscopy; Molecular Structure; Plant Leaves; Psidium; Quercetin; Spectrometry, Mass, Electrospray Ionization | 2012 |
Quercetin glycosides in Psidium guajava L. leaves and determination of a spasmolytic principle.
The traditional herbal remedy from Psidium guajava leaves has been medically proposed in Mexico as effective treatment of acute diarrhea. A methanolic leaf extract was subjected to a bioassay-guided isolation of spasmolytic constituents. Six fractions were separated on a polyvinylpolypyrrolidine (PVPP) column using a water methanol-gradient. The fraction containing flavonols inhibited peristalsis of guinea pig ileum in vitro. A trace of quercetin aglycone together with five glycosides was isolated from this active fraction and identified as quercetin 3-O-alpha-L-arabinoside (guajavarin); quercetin 3-O-beta-D-glucoside (isoquercetin); quercetin 3-O-beta-D-galactoside (hyperin); quercetin 3-O-beta-L-rhamnoside (quercitrin) and quercetin 3-O-gentobioside. Biological activity of each pure compound was studied in the same bioassay. Obtained results suggest that the spasmolytic activity of the Psidium guajava leaf remedy is mainly due to the aglycone quercetin, present in the leaf and in the extract mainly in the form of five flavonols, and whose effect is produced when these products are hydrolyzed by gastrointestinal fluid. Topics: Animals; Antidiarrheals; Drug Evaluation, Preclinical; Gastric Acid; Glycosides; Guinea Pigs; Hydrolysis; Ileum; Male; Methanol; Mexico; Muscle Relaxation; Muscle, Smooth; Parasympatholytics; Plant Extracts; Plants, Medicinal; Quercetin | 1994 |