Compounds > guaifenesin

guaifenesin and acetylcysteine

guaifenesin has been researched along with acetylcysteine in 129 studies

Research

Studies (129)

TimeframeStudies, this research(%)All Research%
pre-199081 (62.79)18.7374
1990's18 (13.95)18.2507
2000's6 (4.65)29.6817
2010's20 (15.50)24.3611
2020's4 (3.10)2.80

Authors

AuthorsStudies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brandon, BM; Rumrill, R; Stolley, PD; Swartz, D; West, SK1
Chodosh, S; Medici, TC1
Wynne, JW1
Blumstein, CG1
Albrecht, HH; Hill, DB; Rogers, DF; Seagrave, J; Solomon, G1
Icard, BL; Rubio, E1
Gobert, JG; Risack, LE; Vandevelde, ME1
Schmidt, OP1
Minette, A1
Horstmann, G; Iravani, J; Melville, GN1
Cobb, OM; Donaldson, JC; Hippensteel, KE; Raymond, LW; Royall, JD; Stoop, DR1
Govan, JR1
Fraunfelder, FT; Tripathi, RC; Wright, P1
Wright, P2
Dietzsch, HJ; Gottschalk, B; Heyne, K; Leupoid, W; Wunderlich, P1
Dempsey, DT; Mercer, DW; Ritchie, WP1
Grove, J; Molon-Noblot, S; Thermes, F1
Andrews, MA; Jenkins, SM; Livingstone, CR; Marriott, C1
Ingrassia, TS; Jett, JR; Keim, LW; Tazelaar, HD1
Halter, F; Haussner, V; Schürer-Maly, CC1
Bury, T; Corhay, JL; Radermecker, MF1
Tiffany, JM2
Critchley, H; Davis, SS; Farraj, NF; Fisher, AN; Illum, L; Johansen, BR; O'Hagan, DT1
Jeffery, PK; Marriott, C; Rogers, DF; Turner, NC1
Gillon, G; Mundy, AR1
Marriott, C1
Birchall, JP; FitzGerald, JE; Green, GG; Pearson, JP1
Ziment, I2
Wallace, JL; Whittle, BJ1
Fregnan, GB; Gazzani, G; Mazzone, A; Pasotti, D; Ricevuti, G1
Benderev, TV1
Cho, CH; Koo, MW; Ogle, CW1
Fantini, L; Frova, C; Mondani, P; Scuri, R1
Henagan, JM; Miller, TA; Schmidt, KL; Smith, GS1
Ayers, MM; Jeffery, PK; Rogers, DF1
Bruni, B; Fedeli, L; Iannacci, L; Palumbo, R; Polidori, R; Rossi, F; Todisco, T1
Del Donno, M; Marsico, SA; Olivieri, D1
Agnew, JE; Clarke, SW; Lauque, D; Lopez-Vidriero, MT; Millar, AB; Pavia, D1
Bender, SW; Hofmann, D; Posselt, HG; Ratjen, F; Stöver, B; Wönne, R1
Fanta, CH1
Dorow, P; Felix, R; Köhler, M; Weiss, T1
Goldstein, IM; Mercandetti, AJ; Millman, FM; Millman, M1
Comer, WT; Martin, TA1
Barrett-Bee, K; Cox, A; Davis, SS; Marriott, C; Readman, AS1
King, R1
Bürgi, H; Regli, J1
Lieberman, J1
Marriott, C; Richards, JH1
Gasset, AR; Shaw, EL1
Bobbio-Pallavicini, F; Carbonera, D; Domenichini, E1
Irwin, RS; Thomas, HM1
Caponegro, PJ; Leadbetter, GW1
Khorvat, A; Tekeresh, M1
Flores, RL; Goddard, RF; Mercer, TT; O'Neill, PX; Sanchez, R1
Taubman, J; Waddell, WR1
Lightowler, JE; Lightowler, NM1
Holley, HS1
Pesce, VD; Ricco, R1
Rocchietta, S1
Muskovitch, ZF1
Collins, B; Guarneri, JJ; Laurenzi, GA; Yin, S1
Absolon, MJ; Brown, CA1
Bláhová, O; Picková, M1
Grundon, W; Millman, M1
Galzigna, L; Reggiani, A1
Carpenter, R; Carson, S; Goldhamer, R1
Smejkal, V1
DeLong, DC; Redman, CE; Streightoff, F1
Hsia, DY; O'Flynn, M; Rowley, WF1
Quayle, G1
Denton, R; Kwart, H; Litt, M1
Lawson, D1
Docter, JM; Eidelman, S; Lillibridge, CB1
Barbieri, EJ1
Bridgman, KM; Huitson, A; Tattersall, AB1
Gargani, GF; Minicucci, L; Nantron, M; Romano, C1
Nagy, G1
Alphin, RS; Callaham, EM; Foxwell, MH; Smith, WL; Yanni, JM1
Goldstein, IM; Goodman, AH; Millman, FM; Millman, M; Van Campen, SS1
Bouchoucha, S; Lentschner, C; Marsac, J; Mayaud, C1
Litt, M; Marriott, C; Martin, R1
Bahari, HM; Ross, IN; Turnberg, LA1
Imamura, N; Misawa, M; Yanaura, S1
Lindgren, I; Mäki, J; Nevalainen, T; Söderström, KO1
Itoh, M; Joh, T; Seno, K; Yokoyama, Y1
App, EM; Coffiner, M; Fossion, J; King, M; Maes, P; Tomkiewicz, RP1
Ahonen, M; Bäck, N; Häppölä, O; Kivilaakso, E; Kiviluoto, T; Mustonen, H; Paimela, H1
App, EM; Coffiner, M; De Sanctis, GT; King, M; Maes, P; Rubin, BK; Tomkiewicz, RP1
Bakaletz, LO; Miyamoto, N1
Chen, HB; Ohno, S; Ou, B; Tanaka, Y; Tsukahara, S; Yamabayashi, S1
Anaizi, NH; Dentinger, PJ; Swenson, CF1
Anderton, P; Tragoulias, S1
Arima, S; Cho, JS; Majima, Y; Min, YG; Rhee, CS; Sakakura, Y1
Matthews, JN; N'Dow, J; Neal, DE; Pearson, JP; Robson, CN1
Aguilera, EJ; Slonimski, M1
Lichtendonk, WJ; Schrier, BP; Witjes, JA1
WEBB, WR1
SEGAL, S1
KOMET, H; SALCO, AN1
De Lisle, RC; Jansson, K; Roach, E1
Caputo, FJ; Deitch, EA; Qin, X; Xu, DZ1
Cutz, E; Mateos-Corral, D; Ratjen, F; Solomon, M1
Albuquerque, RL; de Andrade, GM; de Morais, SM; de Souza, CM; Rao, VS; Rodrigues, Pde A; Santos, FA; Silva, AR; Silva, MG1
Deitch, EA; Dong, W; Feketeova, E; Lee, MA; Lu, Q; Palange, DC; Qin, X; Reino, D; Sharpe, SM; Sheth, SU; Xu, DZ1
Goldmann, T; Hauber, HP; Sprenger, L; Steffen, A; Vollmer, E; Wollenberg, B; Zabel, P1
Johnson, DC1
Sadowska, AM1
Covert, WM; Langley, GD; Soliman, PT; Westin, SN1
Aurich, C; Heuwieser, W; Melkus, E; Schwab, S; Senge, B; Walter, I; Witte, TS1
Callaghan, J; James, S; Neale, JR; Patel, P1
Akhter, J; Chua, TC; Morris, DL; Pillai, K1
Ai, X; Ding, W; Han, X; He, Z; Kou, L; Li, L; Lian, H; Liu, X; Ren, G; Sun, J; Sun, Y; Wang, S; Wang, Y; Wu, C; Zhang, T; Zhang, Y1
Patel, A; Theokli, C1
Carrington, SD; Daniel, BM; Dunican, EM; Erzurum, SC; Fahy, JV; Ghosh, S; Hazen, SL; Hollinger, M; Huang, X; Kerr, SC; Lachowicz-Scroggins, ME; Oscarson, S; Willard, B; Yuan, S1
Lehr, CM; Murgia, X; Schaefer, UF; Schwarzkopf, K; Vukosavljevic, B; Windbergs, M1
Boucher, RC; Delion, MF; Donaldson, SH; Ehre, C; Esther, CR; Fontana, NC; Grubb, BR; Hill, DB; Hothem, LN; Kato, T; Livraghi-Butrico, A; Markovetz, MR; Morrison, CB; Rushton, ZL; Thelin, WR; Villalon, D; Wang, B1
Dahlgren, D; Hedeland, M; Lennernäs, H; Roos, C; Sjöblom, M; Sjögren, E1
Kalyuzhin, OV1
Elgaher, WAM; Haupenthal, J; Hirsch, AKH; Lababidi, N; Ofosu Kissi, E; Rades, T; Schneider, M; Schwarz, BC; Sigal, V1
Bartlett, DL; Beumer, JH; Choudry, HA; Dilly, AK; Elapavaluru, A; Foley, LM; Frederick, R; Guo, J; Hitchens, TK; Honick, BD; Lee, YJ; Makala, H; Rigatti, LH; Velankar, S1
de Souza Carvalho-Wodarz, C; Lababidi, N; Lehr, CM; Montefusco-Pereira, CV; Schneider, M1
Chen, W; Fang, J; Huang, Y; Huang, Z; Liu, Y; Luo, P; Pan, X; Pei, Q; Wang, W; Wu, C; Yan, J; Zeng, J; Zhu, C1
Chen, XB; Deng, ZP; Papi, A; Qu, JM; Tang, W; Wu, F; Xu, JF; Yang, JP; Zhu, D1

Reviews

11 review(s) available for guaifenesin and acetylcysteine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Drug treatment in bronchial asthma.
    Seminars in drug treatment, 1973,Spring, Volume: 2, Issue:4

    Topics: Acetylcysteine; Anti-Bacterial Agents; Asthma; Bronchodilator Agents; Caffeine; Drug Combinations; Ephedrine; Epinephrine; Expectorants; Glucocorticoids; Guaifenesin; Humans; Hypertension; Isoproterenol; Mucus; Sympathomimetics; Theophylline; Xanthines

1973
The role of mucoactive agents in the mechanically ventilated patient: a review of the literature.
    Expert review of respiratory medicine, 2017, Volume: 11, Issue:10

    Topics: Acetylcysteine; Ambroxol; Critical Care; Critical Illness; Deoxyribonuclease I; Expectorants; Guaifenesin; Humans; Intensive Care Units; Mannitol; Mucociliary Clearance; Potassium Dichromate; Recombinant Proteins; Respiration, Artificial; Saline Solution, Hypertonic; Sodium Bicarbonate

2017
[Drug therapy of bronchosecretolytic disorders].
    Medizinische Klinik, 1977, Feb-04, Volume: 72, Issue:5

    Topics: Acetylcysteine; Adrenal Cortex Hormones; Bromhexine; Bronchi; Bronchial Diseases; Cilia; Detergents; Expectorants; Humans; Mucous Membrane; Mucus; Parasympathomimetics; Peptide Hydrolases; Reflex; Water

1977
Plastic bronchitis: an old disease revisited.
    Mayo Clinic proceedings, 1991, Volume: 66, Issue:3

    Topics: Acetylcysteine; Adult; Blood Proteins; Bronchitis; Cough; Diagnosis, Differential; Dyspnea; Eosinophil Granule Proteins; Eosinophils; Humans; Male; Mucus; Prednisone; Ribonucleases; Trimethoprim, Sulfamethoxazole Drug Combination

1991
Acetylcysteine: a drug that is much more than a mucokinetic.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1988, Volume: 42, Issue:8

    Topics: Acetylcysteine; Administration, Oral; Aerosols; Humans; Instillation, Drug; Mucus

1988
Clinical aspects of mucus and mucous plugging in asthma.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 1985, Volume: 22, Issue:6

    Topics: Acetylcysteine; Asthma; Biological Transport; Bronchi; Cilia; Expectorants; Humans; Mucus; Pulmonary Atelectasis; Sputum; Terbutaline; Trachea; Viscosity

1985
Theory and practice of the use of expectorants reviewed from clinical aspects.
    Therapia Hungarica (English edition), 1984, Volume: 32, Issue:1

    Topics: Acetylcysteine; Bromhexine; Carbocysteine; Cilia; Cough; Expectorants; Guaiacol; Humans; Mucus; Polyethylene Glycols; Respiratory Tract Diseases; Sputum; Terpenes; Theophylline; Viscosity

1984
N-Acetylcysteine mucolysis in the management of chronic obstructive pulmonary disease.
    Therapeutic advances in respiratory disease, 2012, Volume: 6, Issue:3

    Topics: Acetylcysteine; Expectorants; Gene Expression Regulation; Humans; Inflammation; Mucins; Mucus; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Reactive Oxygen Species; Signal Transduction

2012
The role of mucoregulatory agents after continence-preserving urinary diversion surgery.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2012, Mar-15, Volume: 69, Issue:6

    Topics: Acetylcysteine; Aspirin; Expectorants; Gastrointestinal Agents; Humans; Length of Stay; Mucus; Octreotide; Ranitidine; Urea; Urinary Diversion

2012
Effect of N-acetylcysteine on mucosal immunity of respiratory tract.
    Terapevticheskii arkhiv, 2018, Apr-19, Volume: 90, Issue:3

    Topics: Acetylcysteine; Expectorants; Humans; Immunity, Mucosal; Mucociliary Clearance; Mucus

2018

Trials

13 trial(s) available for guaifenesin and acetylcysteine

ArticleYear
[Defence capacities of the respiratory tract].
    Schweizerische medizinische Wochenschrift, 1975, Aug-02, Volume: 105, Issue:31

    Topics: Acetylcysteine; Aerosols; Drug Combinations; Gases; Guaifenesin; Humans; Isoproterenol; Lung Diseases, Obstructive; Mucous Membrane; Phagocytosis; Placebos; Respiratory System; Sputum; Viscosity

1975
Serum, sputum and bronchial concentrations of erythromycin in chronic bronchitis after single and multiple treatments with either propionate-N-acetylcysteinate or stearate erythromycin.
    Chemotherapy, 1988, Volume: 34, Issue:5

    Topics: Acetylcysteine; Administration, Oral; Bronchi; Bronchitis; Chronic Disease; Double-Blind Method; Erythromycin; Female; Humans; Intestinal Absorption; Male; Middle Aged; Mucus; Sputum

1988
Effect of N-acetylcysteine in subjects with slow pulmonary mucociliary clearance.
    European journal of respiratory diseases. Supplement, 1985, Volume: 139

    Topics: Acetylcysteine; Adult; Cilia; Double-Blind Method; Female; Humans; Lung; Male; Mucus; Random Allocation; Stimulation, Chemical

1985
Improvement of mucociliary transport in smokers by mucolytics.
    European journal of respiratory diseases. Supplement, 1985, Volume: 139

    Topics: Acetylcysteine; Adult; Ambroxol; Biological Transport; Bromhexine; Bronchitis; Cilia; Double-Blind Method; Female; Humans; Male; Middle Aged; Mucus; Random Allocation; Smoking; Trachea

1985
Effect of oral N-acetylcysteine on mucus clearance.
    British journal of diseases of the chest, 1985, Volume: 79, Issue:3

    Topics: Acetylcysteine; Administration, Oral; Aged; Bronchitis; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Lung; Male; Mucus; Respiratory Function Tests

1985
A double-blind placebo controlled trial with oral ambroxol and N-acetylcysteine for mucolytic treatment in cystic fibrosis.
    European journal of pediatrics, 1985, Volume: 144, Issue:4

    Topics: Acetylcysteine; Adolescent; Adult; Ambroxol; Bromhexine; Child; Clinical Trials as Topic; Cystic Fibrosis; Double-Blind Method; Expectorants; Female; Humans; Male; Mucus; Respiratory Function Tests

1985
Influence of tasuldine and acetylcysteine on mucociliary clearance in patients with chronic airways obstruction.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:1

    Topics: Acetylcysteine; Adult; Aged; Cilia; Expectorants; Humans; Lung; Lung Diseases, Obstructive; Middle Aged; Mucus; Pyrimidines; Respiratory Function Tests

1986
[Mucolytic therapy using N-acetylcysteine in chronic obstructive bronchitis].
    Deutsche medizinische Wochenschrift (1946), 1968, Jul-12, Volume: 93, Issue:28

    Topics: Acetylcysteine; Adult; Aged; Bronchitis; Chronic Disease; DNA; Glycosaminoglycans; Humans; In Vitro Techniques; Middle Aged; Mucus; Respiratory Therapy

1968
Irish general practice study of acetylcysteine (Fabrol) in chronic bronchitis.
    The Journal of international medical research, 1984, Volume: 12, Issue:2

    Topics: Acetylcysteine; Aged; Bronchitis; Chronic Disease; Clinical Trials as Topic; Family Practice; Female; Humans; Male; Middle Aged; Mucus; Sputum; Time Factors; Viscosity

1984
[Controlled clinical study on the activity of a new mucoregulating drug in obstructive bronchial pathology with a marked hypersecretory feature. The pediatric experience].
    Minerva pediatrica, 1984, Feb-15, Volume: 36, Issue:3

    Topics: Acetylcysteine; Adolescent; Ambroxol; Bromhexine; Bronchial Diseases; Child; Child, Preschool; Clinical Trials as Topic; Cystic Fibrosis; Female; Humans; Male; Mucus

1984
Reducing mucus production after urinary reconstruction: a prospective randomized trial.
    The Journal of urology, 2001, Volume: 165, Issue:5

    Topics: Acetylcysteine; Administration, Intravesical; Administration, Oral; Aspirin; Cross-Over Studies; Double-Blind Method; Humans; Ileum; Intestinal Mucosa; Mucins; Mucus; Prospective Studies; Quality of Life; Ranitidine; Surveys and Questionnaires; Urinary Bladder; Urinary Diversion; Viscosity

2001
Premedication with N-acetylcysteine and simethicone improves mucosal visualization during gastroscopy: a randomized, controlled, endoscopist-blinded study.
    European journal of gastroenterology & hepatology, 2013, Volume: 25, Issue:7

    Topics: Acetylcysteine; Adult; Aged; Chi-Square Distribution; Duodenum; Endoscopy, Digestive System; England; Esophagogastric Junction; Expectorants; Female; Gastric Mucosa; Humans; Intestinal Mucosa; Male; Middle Aged; Mucus; Predictive Value of Tests; Premedication; Simethicone; Surface-Active Agents; Therapeutic Irrigation; Time Factors; Young Adult

2013
Intravenous N-acetylcysteine in respiratory disease with abnormal mucus secretion.
    European review for medical and pharmacological sciences, 2023, Volume: 27, Issue:11

    Topics: Acetylcysteine; Ambroxol; Double-Blind Method; Expectorants; Humans; Mucus; Respiration Disorders

2023

Other Studies

105 other study(ies) available for guaifenesin and acetylcysteine

ArticleYear
Drugs used in the treatment of asthma.
    Comprehensive therapy, 1977, Volume: 3, Issue:1

    Topics: Acetylcysteine; Adrenal Cortex Hormones; Aerosols; Asthma; Cromolyn Sodium; Dexamethasone; Drug Combinations; Ephedrine; Epinephrine; Guaifenesin; Humans; Isoproterenol; Metaproterenol; Theophylline

1977
Chronic obstructive pulmonary disease.
    Comprehensive therapy, 1975, Volume: 1, Issue:8

    Topics: Acetylcysteine; Aerosols; Anti-Bacterial Agents; Bronchodilator Agents; Chronic Disease; Expectorants; Guaifenesin; Heart Failure; Humans; Humidity; Lung Diseases, Obstructive; Patient Education as Topic; Physical Therapy Modalities; Prednisone

1975
Effects of guaifenesin, N-acetylcysteine, and ambroxol on MUC5AC and mucociliary transport in primary differentiated human tracheal-bronchial cells.
    Respiratory research, 2012, Oct-31, Volume: 13

    Topics: Acetylcysteine; Ambroxol; Cells, Cultured; Expectorants; Guaifenesin; Humans; Interleukin-13; Mucin 5AC; Mucociliary Clearance; Respiratory Mucosa

2012
Effect of thiol derivatives on mixed mucus and blood clots in vitro.
    Resuscitation, 1978, Volume: 6, Issue:1

    Topics: Acetylcysteine; Blood Coagulation; Dithiothreitol; Expectorants; Humans; In Vitro Techniques; Mercaptoethanol; Mesna; Mucus; Respiratory System; Saline Solution, Hypertonic

1978
[Conclusions of an international symposium held at Aachen on 4 and 5 May about mucolytic agents, especially oral acetylcysteine].
    Revue de l'Institut d'hygiene des mines, 1979, Volume: 34, Issue:3

    Topics: Acetylcysteine; Airway Obstruction; Bronchi; Evaluation Studies as Topic; Expectorants; Humans; Mucus

1979
N-Acetylcysteine and mucociliary activity in mammalian airways.
    Arzneimittel-Forschung, 1978, Volume: 28, Issue:2

    Topics: Acetylcysteine; Animals; Bronchi; Cilia; Female; Mucus; Orthomyxoviridae Infections; Rabbits; Rats

1978
Acetylcysteine for life-threatening acute bronchial obstruction.
    Annals of internal medicine, 1978, Volume: 88, Issue:5

    Topics: Acetylcysteine; Acute Disease; Adult; Airway Obstruction; Bronchial Diseases; Female; Humans; Male; Middle Aged; Mucus

1978
Mucoid strains of Pseudomonas aeruginosa: the influence of culture medium on the stability of mucus production.
    Journal of medical microbiology, 1975, Volume: 8, Issue:4

    Topics: Acetylcysteine; Cetrimonium Compounds; Citrates; Culture Media; Cystic Fibrosis; Deoxycholic Acid; Ferric Compounds; Humans; Lactose; Mucus; Neutral Red; Phosphatidylcholines; Polysorbates; Pseudomonas aeruginosa; Sodium Dodecyl Sulfate; Species Specificity; Surface-Active Agents; Thiosulfates

1975
Corneal mucus plaques.
    American journal of ophthalmology, 1977, Volume: 83, Issue:2

    Topics: Acetylcysteine; Adult; Aged; Cornea; Corneal Diseases; Epithelial Cells; Epithelium; Female; Humans; Keratoconjunctivitis; Male; Middle Aged; Mucus

1977
Filamentary keratitis.
    Transactions of the ophthalmological societies of the United Kingdom, 1975, Volume: 95, Issue:2

    Topics: Acetylcysteine; Binding Sites; Glycoproteins; Histocytochemistry; Humans; Keratitis; Keratoconjunctivitis; Lipids; Microscopy, Polarization; Mucus

1975
Cystic fibrosis: comparison of two mucolytic drugs for inhalation treatment (acetylcysteine and arginine hydrochloride).
    Pediatrics, 1975, Volume: 55, Issue:1

    Topics: Acetylcysteine; Aerosols; Arginine; Bronchoscopy; Carbon Dioxide; Child; Child, Preschool; Cough; Cystic Fibrosis; Drug Evaluation; Expectorants; Female; Humans; Male; Mucus; Oxygen; Radionuclide Imaging; Respiration; Respiratory Function Tests; Spirometry; Sputum

1975
The dry eye.
    The Practitioner, 1975, Volume: 214, Issue:1283

    Topics: Acetylcysteine; Anti-Bacterial Agents; Blepharitis; Conjunctivitis; Cornea; Epithelium; Expectorants; Eye Diseases; Folliculitis; Humans; Keratoconjunctivitis; Lacrimal Apparatus; Mucus; Tears; Time Factors

1975
Do sensory neurons mediate adaptive cytoprotection of gastric mucosa against bile acid injury?
    American journal of surgery, 1992, Volume: 163, Issue:1

    Topics: Acetylcysteine; Adaptation, Physiological; Animals; Bile Acids and Salts; DNA; Gastric Mucosa; Lidocaine; Mucus; Neurons, Afferent; Rats; Rats, Inbred Strains; Taurocholic Acid

1992
Effects of acetylcysteine on rabbit conjunctival and corneal surfaces. A scanning electron microscopy study.
    Investigative ophthalmology & visual science, 1991, Volume: 32, Issue:11

    Topics: Acetylcysteine; Administration, Topical; Animals; Conjunctiva; Cornea; Epithelium; Microscopy, Electron, Scanning; Mucus; Rabbits

1991
Model systems for the evaluation of mucolytic drugs: acetylcysteine and S-carboxymethylcysteine.
    The Journal of pharmacy and pharmacology, 1990, Volume: 42, Issue:2

    Topics: Acetylcysteine; Animals; Carbocysteine; Chromatography, Gel; Cysteine; Elasticity; Expectorants; In Vitro Techniques; Male; Microscopy, Electron, Scanning; Models, Biological; Mucus; Rats; Rats, Inbred Strains; Swine; Swine, Miniature; Trachea; Viscosity

1990
Effect of 16.16 dimethyl prostaglandin E2, N-acetyl-cysteine and the proton pump inhibitor BY 831-78 on hydrogen peroxide-induced mucosal damage in the rat stomach.
    Digestion, 1990, Volume: 46, Issue:2

    Topics: 16,16-Dimethylprostaglandin E2; Acetylcysteine; Adenosine Triphosphatases; Animals; Benzimidazoles; Gastric Juice; Gastric Mucosa; Gastritis; Hydrogen Peroxide; Male; Mucus; Rats; Rats, Inbred Strains

1990
[Kinetics of mucus].
    Revue medicale de Liege, 1990, Jan-01, Volume: 45, Issue:1

    Topics: Acetylcysteine; Antitussive Agents; Bromhexine; Cough; Expectorants; Humans; Lung Diseases, Obstructive; Mucus; Propiophenones

1990
Measurement of wettability of the corneal epithelium. I. Particle attachment method.
    Acta ophthalmologica, 1990, Volume: 68, Issue:2

    Topics: Acetylcysteine; Adhesiveness; Animals; Cornea; Dimethyl Sulfoxide; Epithelium; Methods; Mucus; Polystyrenes; Rabbits; Solutions; Spores, Bacterial; Surface Tension

1990
Measurement of wettability of the corneal epithelium. II. Contact angle method.
    Acta ophthalmologica, 1990, Volume: 68, Issue:2

    Topics: Acetylcysteine; Adhesiveness; Animals; Cornea; Epithelium; Female; Male; Methods; Mucus; Rabbits; Sodium Chloride; Surface Tension

1990
Nasal absorption enhancers for biosynthetic human growth hormone in rats.
    Pharmaceutical research, 1990, Volume: 7, Issue:7

    Topics: Absorption; Acetylcysteine; Animals; Enzyme-Linked Immunosorbent Assay; Growth Hormone; Humans; Leucine; Lysophosphatidylcholines; Male; Mucus; Nasal Mucosa; Palmitoylcarnitine; Rats; Rats, Inbred Strains; Viscosity

1990
Oral N-acetylcysteine or S-carboxymethylcysteine inhibit cigarette smoke-induced hypersecretion of mucus in rat larynx and trachea in situ.
    The European respiratory journal, 1989, Volume: 2, Issue:10

    Topics: Acetylcysteine; Animals; Carbocysteine; Cysteine; Fucose; Hexoses; Larynx; Male; Mucus; Nicotiana; Plants, Toxic; Rats; Rats, Inbred Strains; Serum Albumin; Smoke; Specific Pathogen-Free Organisms; Trachea

1989
The dissolution of urinary mucus after cystoplasty.
    British journal of urology, 1989, Volume: 63, Issue:4

    Topics: Acetylcysteine; Carbocysteine; Expectorants; Humans; In Vitro Techniques; Mucus; Postoperative Complications; Urea; Urinary Bladder; Urine

1989
Mucolytic agents for glue ear.
    Lancet (London, England), 1985, Nov-09, Volume: 2, Issue:8463

    Topics: Acetylcysteine; Administration, Oral; Carbocysteine; Child; Cysteine; Humans; In Vitro Techniques; Mucus; Otitis Media with Effusion

1985
Rheologic studies on middle ear effusions and their mucus glycoproteins.
    Archives of otolaryngology--head & neck surgery, 1989, Volume: 115, Issue:4

    Topics: Acetylcysteine; Carbocysteine; Child; Glycoproteins; Humans; In Vitro Techniques; Mercaptoethanol; Mucus; Otitis Media with Effusion; Rheology; Viscosity

1989
Role of mucus in the repair of gastric epithelial damage in the rat. Inhibition of epithelial recovery by mucolytic agents.
    Gastroenterology, 1986, Volume: 91, Issue:3

    Topics: Acetylcysteine; Animals; Ethanol; Gastric Mucosa; Male; Mucus; Pepsin A; Rats; Rats, Inbred Strains

1986
Acetylcysteine for urinary tract mucolysis.
    The Journal of urology, 1988, Volume: 139, Issue:2

    Topics: Acetylcysteine; Adult; Humans; Ileum; Male; Mucus; Postoperative Complications; Recurrence; Ureter; Ureteral Obstruction

1988
Effects of verapamil, carbenoxolone and N-acetylcysteine on gastric wall mucus and ulceration in stressed rats.
    Pharmacology, 1986, Volume: 32, Issue:6

    Topics: Acetylcysteine; Animals; Carbenoxolone; Cold Temperature; Drug Administration Schedule; Female; Gastric Mucosa; Glycyrrhetinic Acid; Mucus; Rats; Rats, Inbred Strains; Restraint, Physical; Stomach Ulcer; Stress, Physiological; Verapamil

1986
Nesosteine: a new mucoregulatory agent.
    Drugs under experimental and clinical research, 1986, Volume: 12, Issue:8

    Topics: Acetylcysteine; Animals; Bronchi; Expectorants; Male; Mucus; Rabbits; Terpenes; Thiazoles; Tiopronin; Trachea; Viscosity

1986
N-acetyl-cysteine and prostaglandin. Comparable protection against experimental ethanol injury in the stomach independent of mucus thickness.
    Annals of surgery, 1986, Volume: 204, Issue:6

    Topics: Acetylcysteine; Animals; Ethanol; Female; Gastric Mucosa; Mucus; Prostaglandins E, Synthetic; Random Allocation; Rats; Rats, Inbred Strains

1986
Acetylcysteine: a drug with an interesting past and a fascinating future.
    Respiration; international review of thoracic diseases, 1986, Volume: 50 Suppl 1

    Topics: Acetylcysteine; Animals; Humans; Mucus

1986
Effect of oral acetylcysteine on tobacco smoke-induced secretory cell hyperplasia.
    European journal of respiratory diseases. Supplement, 1985, Volume: 139

    Topics: Acetylcysteine; Animals; Bronchi; Germ-Free Life; Hyperplasia; Male; Mucus; Nicotiana; Plants, Toxic; Rats; Rats, Inbred Strains; Smoke

1985
Use of acetylcysteine in bronchial asthma--another look.
    Annals of allergy, 1985, Volume: 54, Issue:4

    Topics: Acetylcysteine; Asthma; Bronchoscopy; Humans; Lung; Mucus; Respiratory Therapy; Therapeutic Irrigation

1985
N-[[(Mercaptoacetyl)amino]benzoyl]glycines as mucolytic agents.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:7

    Topics: Acetylcysteine; Aminobenzoates; Animals; Chemical Phenomena; Chemistry; Drug Stability; Expectorants; Glycine; Humans; Isomerism; Lethal Dose 50; Mice; Mucus; Rats; Salts; Sputum; Water

1985
A new mucotropic agent--in vitro and in vivo evaluation of 2-alpha-thenoylthiopropionylglycine (bronchoplus).
    European journal of respiratory diseases, 1985, Volume: 67, Issue:2

    Topics: Acetylcysteine; Animals; Dithiothreitol; Expectorants; Glycine; Humans; Hydrogen-Ion Concentration; Hydrolysis; Models, Biological; Mucus; Rheology; Sulfides; Swine; Swine, Miniature; Thiophenes; Time Factors; Viscosity

1985
Acetylcysteine in airway maintenance.
    Lancet (London, England), 1967, Apr-22, Volume: 1, Issue:7495

    Topics: Acetylcysteine; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Intubation, Intratracheal; Mucus; Respiration, Artificial

1967
The appropriate use of mucolytic agents.
    The American journal of medicine, 1970, Volume: 49, Issue:1

    Topics: Acetylcysteine; Anti-Bacterial Agents; Ascorbic Acid; Bronchi; Bronchitis; Bronchodilator Agents; Deoxyribonucleases; DNA; Edetic Acid; Epithelium; Glycosaminoglycans; Humans; Mucus; Peptide Hydrolases; Respiratory Therapy; Sputum; Trachea; Urea; Viscosity

1970
The effects of storage and of potassium iodide, urea, N-acetyl-cysteine and triton X-100 on the viscosity of bronchial mucus.
    British journal of diseases of the chest, 1974, Volume: 68, Issue:0

    Topics: Acetylcysteine; Asthma; Bronchi; Bronchitis; Centrifugation; Humans; Mucus; Polyethylene Glycols; Potassium Iodide; Preservation, Biological; Specimen Handling; Sputum; Surface-Active Agents; Urea; Viscosity

1974
Management of an unusual case of keratitis mucosa with hydrophilic contact lenses and N-acetylcysteine.
    Annals of ophthalmology, 1974, Volume: 6, Issue:10

    Topics: Acetylcysteine; Adult; Contact Lenses, Hydrophilic; Epithelium; Female; Humans; Keratitis; Mucus

1974
[Mucolytic and therapeutic effects of acetylcysteine administered by the intravenous route. Experiences in resuscitation].
    Minerva anestesiologica, 1973, Volume: 39, Issue:1

    Topics: Acetylcysteine; Adolescent; Adult; Aged; Female; Humans; Injections, Intravenous; Male; Middle Aged; Mucus; Respiratory Insufficiency; Resuscitation; Viscosity

1973
Mucoid inpaction of the bronchus. Diagnosis and treatment.
    The American review of respiratory disease, 1973, Volume: 108, Issue:4

    Topics: Acetylcysteine; Adult; Airway Obstruction; Asthma; Bronchial Diseases; Bronchitis; Female; Humans; Intubation, Intratracheal; Mucus; Radiography

1973
Acute ureteral obstruction secondary to mucoid impaction in supravesical diversion. Treatment with N-acetylcysteine.
    Urology, 1974, Volume: 3, Issue:4

    Topics: Acetylcysteine; Adult; Colon, Sigmoid; Female; Humans; Hydronephrosis; Ileum; Male; Mucus; Postoperative Complications; Proteins; Radiography; Ureter; Ureteral Obstruction; Urinary Diversion

1974
[Effect of mucosolvin on the structure of mucoid mucus].
    Vestnik khirurgii imeni I. I. Grekova, 1974, Volume: 112, Issue:5

    Topics: Acetylcysteine; Bronchi; Humans; Mucus

1974
Output characteristics and clinical efficacy of ultrasonic nebulizers.
    The Journal of asthma research, 1968, Volume: 5, Issue:4

    Topics: Acetylcysteine; Aerosols; Asthma; Bronchial Diseases; Child; Cortisone; Cystic Fibrosis; Humans; Mucus; Pancreatic Diseases; Penicillin G; Positive-Pressure Respiration; Radioisotopes; Sarcina; Sputum; Ultrasonic Therapy; Ultrasonics

1968
Mechanical and chemical methods of opening occluded T tubes.
    Surgery, 1972, Volume: 71, Issue:1

    Topics: Acetylcysteine; Bile Ducts; Catheterization; Drainage; Humans; Male; Methods; Middle Aged; Mucus; Silicones

1972
Comparative mucolytic studies on dithiothreitol, N-acetyl-cysteine and L-cysteine on human respiratory mucus in vitro and their effects on the rate of flow of mucus in the exposed trachea of the rat on topical application.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 189, Issue:1

    Topics: Acetylcysteine; Animals; Bronchi; Cysteine; Dithiothreitol; Humans; In Vitro Techniques; Irritants; Models, Biological; Mucus; Rats; Rheology; Stimulation, Chemical; Trachea; Viscosity

1971
Humidification and mist therapy in chronic obstructive lung disease.
    International anesthesiology clinics, 1970,Fall, Volume: 8, Issue:3

    Topics: Acetylcysteine; Anti-Bacterial Agents; Bronchi; Bronchodilator Agents; Chronic Disease; Deoxyribonucleases; Humans; Humidity; Lung Diseases, Obstructive; Mucus; Pulmonary Diffusing Capacity; Pulmonary Surfactants; Respiratory Therapy; Sterilization; Surface-Active Agents; Trypsin; Ultrasonic Therapy; Ventilators, Mechanical

1970
[On the results of histochemical studies with mucolytic agents].
    Bollettino della Societa italiana di biologia sperimentale, 1970, Apr-15, Volume: 46, Issue:7

    Topics: Acetylcysteine; Aniline Compounds; In Vitro Techniques; Mucus; Toluene

1970
[Mucolytic agents for inhalation].
    Bollettino chimico farmaceutico, 1970, Volume: 109, Issue:12

    Topics: Acetylcysteine; Aerosols; Cystic Fibrosis; Humans; Mucus; Respiratory Therapy

1970
Mucomyst.
    Annals of allergy, 1970, Volume: 28, Issue:3

    Topics: Acetylcysteine; Humans; Mucus; Respiratory Hypersensitivity

1970
Mucus flow in the mammalian trachea.
    Aspen Emphysema Conference, 1967, Volume: 10

    Topics: Acetylcysteine; Adenosine Triphosphate; Aerosols; Air Pollution; Animals; Carbon; Cats; Cilia; Digitalis Glycosides; Epinephrine; Injections, Intravenous; Isoproterenol; Methods; Mucus; Oxygen; Rheology; Serotonin; Spores; Strophanthins; Surface-Active Agents; Trachea

1967
Acetylcysteine in kerato-conjunctivitis sicca.
    The British journal of ophthalmology, 1968, Volume: 52, Issue:4

    Topics: Acetylcysteine; Adolescent; Adult; Aged; Arthritis, Rheumatoid; Child; Child, Preschool; Cornea; Female; Humans; Keratoconjunctivitis; Lacrimal Apparatus; Male; Methylcellulose; Middle Aged; Mucus; Salivary Glands; Sarcoidosis; Tears; Xerostomia

1968
[Therapy with aerosols in infants and small children at the otorhinolaryngology departments].
    Zeitschrift fur Laryngologie, Rhinologie, Otologie und ihre Grenzgebiete, 1968, Volume: 47, Issue:8

    Topics: Acetylcysteine; Aerosols; Age Factors; Child, Preschool; Humans; Infant; Infant, Newborn; Mucus; Nasal Mucosa; Otorhinolaryngologic Diseases; Respiratory Therapy; Trachea; Viscosity

1968
Use of acetylcysteine in bronchial asthma and emphysema.
    The Journal of asthma research, 1969, Volume: 6, Issue:4

    Topics: Acetylcysteine; Adolescent; Adult; Aerosols; Aged; Asthma; Bronchitis; Child; Chronic Disease; Ethanol; Female; Humans; Isoproterenol; Male; Middle Aged; Mucus; Pulmonary Emphysema; Respiratory Function Tests; Rhinitis, Allergic, Seasonal; Surface-Active Agents

1969
[On the mechanism of the mucolytic action of N-acetyl-L-cysteine].
    Bollettino della Societa italiana di biologia sperimentale, 1965, Jan-15, Volume: 41, Issue:1

    Topics: Acetylcysteine; Bronchi; Humans; Mucoproteins; Mucous Membrane; Mucus

1965
Mucolytic agent.
    British medical journal, 1966, Sep-10, Volume: 2, Issue:5514

    Topics: Acetylcysteine; Bronchitis; Cystic Fibrosis; Humans; Mucus; Tracheotomy

1966
Responses of ciliated epithelium to irritants. Mucus transport in the respiratory tract.
    The American review of respiratory disease, 1966, Volume: 93, Issue:3

    Topics: Acetylcysteine; Animals; Cats; Epithelium; Female; Isoproterenol; Lobeline; Male; Mucus; Nicotine; Respiratory Physiological Phenomena; Smoking

1966
[The mucolytic effect of N-acetylcysteine on the secretions of the respiratory tract in vitro].
    Ceskoslovenska pediatrie, 1966, Volume: 21, Issue:12

    Topics: Acetylcysteine; Child; Child, Preschool; Humans; In Vitro Techniques; Mucus; Paranasal Sinuses

1966
In vivo antiviral chemotherapy. II. Anti-influenza action of compounds affecting mucous secretions.
    Antimicrobial agents and chemotherapy, 1966, Volume: 6

    Topics: Acetylcysteine; Animals; Cysteine; Mice; Mucus; Orthomyxoviridae Infections; Parasympatholytics; Parasympathomimetics

1966
Cystic fibrosis of the pancreas.
    Advances in cardiopulmonary diseases, 1966, Volume: 3

    Topics: Acetylcysteine; Anti-Bacterial Agents; Bronchi; Bronchial Diseases; Child; Cystic Fibrosis; Digestive System; Drainage; Fecal Impaction; Humans; Hyperglycemia; Intestinal Obstruction; Liver Cirrhosis; Lung; Lung Diseases; Meconium; Mucus; Pneumatosis Cystoides Intestinalis; Respiratory Function Tests; Respiratory Insufficiency; Respiratory Therapy; Respiratory Tract Diseases; Salivary Glands; Sweat

1966
[N-acetyl-L-cysteine (Mucofilin), a mucolytic agent, apropos of bronchial secretions].
    Masui. The Japanese journal of anesthesiology, 1966, Volume: 15, Issue:1

    Topics: Acetylcysteine; Bronchi; Humans; Intubation, Intratracheal; Masks; Mucus; Postoperative Care; Sputum; Tracheotomy

1966
N-acetylcysteine in cystic fibrosis. Mechanical and chemical factors in treatment by aerosol.
    The American review of respiratory disease, 1967, Volume: 95, Issue:4

    Topics: Acetylcysteine; Adolescent; Adult; Aerosols; Agammaglobulinemia; Bronchiectasis; Child; Child, Preschool; Cystic Fibrosis; Drug Stability; Female; Humans; Male; Masks; Mucus

1967
Penetrability of mucus by antibiotics.
    Bibliotheca paediatrica, 1967, Volume: 86

    Topics: Acetylcysteine; Anti-Bacterial Agents; In Vitro Techniques; Mucins; Mucus; Permeability

1967
Oral administration of n-acetyl cysteine in the prophylaxis of "meconium ileus equivalent".
    The Journal of pediatrics, 1967, Volume: 71, Issue:6

    Topics: Acetylcysteine; Adult; Cystic Fibrosis; Enema; Humans; Intestinal Obstruction; Male; Meconium; Mucus; Pancreas; Pharmaceutical Vehicles

1967
Mucolytics and oral acetylcysteine. A symposium of Inpharzam International, Switzerland.
    European journal of respiratory diseases. Supplement, 1980, Volume: 111

    Topics: Acetylcysteine; Administration, Oral; Animals; Congresses as Topic; Humans; Mucus; Switzerland

1980
Mucolytics.
    American family physician, 1983, Volume: 28, Issue:2

    Topics: Acetylcysteine; Carbocysteine; Humans; Mucus; Nasal Mucosa; Peptide Hydrolases

1983
A method for measuring changes in tracheal mucus gel layer thickness as an indication of an immediate hypersensitivity response.
    International archives of allergy and applied immunology, 1984, Volume: 74, Issue:4

    Topics: Acetylcysteine; Aluminum Hydroxide; Animals; Atropine; Chromones; Cimetidine; Cromolyn Sodium; Dose-Response Relationship, Immunologic; Expectorants; Hypersensitivity, Immediate; Immune Sera; Methods; Methysergide; Mucus; Ovalbumin; Pyrilamine; Rats; Rats, Inbred Strains; Trachea

1984
Status Asthmaticus: use of acetylcysteine during bronchoscopy and lavage to remove mucous plugs.
    Annals of allergy, 1983, Volume: 50, Issue:2

    Topics: Acetylcysteine; Adult; Asthma; Bronchoscopy; Child; Female; Humans; Male; Middle Aged; Mucus; Therapeutic Irrigation

1983
[Thiamphenicol glycinate acetylcysteinate in the treatment of acute respiratory infections with mucostasis].
    European journal of respiratory diseases. Supplement, 1980, Volume: 111

    Topics: Acetylcysteine; Acute Disease; Adult; Anti-Bacterial Agents; Child; Drug Combinations; Expectorants; Humans; Mucus; Respiratory Tract Infections; Thiamphenicol

1980
The effect of mucolytic agents on the rheologic and transport properties of canine tracheal mucus.
    The American review of respiratory disease, 1980, Volume: 121, Issue:3

    Topics: Acetylcysteine; Animals; Carbocysteine; Cysteine; Dithiothreitol; Dogs; Elasticity; Expectorants; In Vitro Techniques; Mucus; Potassium Iodide; Rana catesbeiana; Rheology; Trachea; Urea; Viscosity

1980
The pH gradient across mucus adherent to rat fundic mucosa in vivo and the effect of potential damaging agents.
    Gastroenterology, 1981, Volume: 81, Issue:4

    Topics: Acetylcysteine; Animals; Aspirin; Bicarbonates; Gastric Mucosa; Hydrogen-Ion Concentration; In Vitro Techniques; Mucus; Rats; Taurocholic Acid

1981
Effects of expectorants on the canine tracheal ciliated cells.
    Japanese journal of pharmacology, 1981, Volume: 31, Issue:6

    Topics: Acetylcholine; Acetylcysteine; Animals; Bromhexine; Cilia; Cysteine; Dogs; Expectorants; In Vitro Techniques; Male; Mucus; Potassium; Trachea

1981
Effect of mucolytic pretreatment on gastric mucosal coating with barium sulfate in the rat. A scanning electron microscopic investigation.
    Acta radiologica: diagnosis, 1980, Volume: 21, Issue:4

    Topics: Acetylcysteine; Animals; Barium Sulfate; Bicarbonates; Contrast Media; Female; Gastric Mucosa; Male; Microscopy, Electron, Scanning; Mucus; Rats

1980
Role of mucus in gastric mucosal injury induced by local ischemia/reperfusion.
    The Journal of laboratory and clinical medicine, 1995, Volume: 126, Issue:3

    Topics: Acetylcysteine; Alcian Blue; Animals; Chromium Radioisotopes; Diterpenes; Edetic Acid; Gastric Mucosa; Hexosamines; Ischemia; Male; Mucus; Periodic Acid-Schiff Reaction; Rats; Rats, Sprague-Dawley; Reperfusion Injury

1995
Mucolytic treatment with N-acetylcysteine L-lysinate metered dose inhaler in dogs: airway epithelial function changes.
    The European respiratory journal, 1994, Volume: 7, Issue:1

    Topics: Acetylcysteine; Animals; Bronchi; Dogs; Epithelium; In Vitro Techniques; Lysine; Mucociliary Clearance; Mucus; Nebulizers and Vaporizers; Rana pipiens; Rheology; Trachea

1994
Preepithelial mucus-HCO-3 layer protects against intracellular acidosis in acid-exposed gastric mucosa.
    The American journal of physiology, 1993, Volume: 264, Issue:1 Pt 1

    Topics: Acetylcysteine; Acidosis; Acids; Animals; Bicarbonates; Gastric Mucosa; Hydrogen-Ion Concentration; Intracellular Membranes; Mucus; Necturus maculosus; Pepsin A

1993
A comparison of a new mucolytic N-acetylcysteine L-lysinate with N-acetylcysteine: airway epithelial function and mucus changes in dog.
    Pulmonary pharmacology, 1995, Volume: 8, Issue:6

    Topics: Acetylcysteine; Administration, Inhalation; Animals; Bronchi; Dogs; Expectorants; Female; Lysine; Male; Mucociliary Clearance; Mucus; Trachea; Viscosity

1995
Selective adherence of non-typeable Haemophilus influenzae (NTHi) to mucus or epithelial cells in the chinchilla eustachian tube and middle ear.
    Microbial pathogenesis, 1996, Volume: 21, Issue:5

    Topics: Acetylcysteine; Animals; Bacterial Adhesion; Bacterial Outer Membrane Proteins; Bordetella pertussis; Chinchilla; Ear, Middle; Epithelium; Eustachian Tube; Expectorants; Haemophilus influenzae; Membrane Glycoproteins; Microfilament Proteins; Mucus

1996
Structure and composition of rat precorneal tear film. A study by an in vivo cryofixation.
    Investigative ophthalmology & visual science, 1997, Volume: 38, Issue:2

    Topics: Acetylcysteine; Animals; Cornea; Cryopreservation; Freeze Substitution; Lacrimal Apparatus; Microscopy, Electron; Microscopy, Electron, Scanning; Mucus; Rats; Rats, Wistar; Tears

1997
Stability of acetylcysteine in an extemporaneously compounded ophthalmic solution.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1997, Mar-01, Volume: 54, Issue:5

    Topics: Acetylcysteine; Chromatography, High Pressure Liquid; Drug Stability; Humans; Hydrogen-Ion Concentration; Mucus; Ophthalmic Solutions; Temperature

1997
Mucous contribution to rat tear-film thickness measured with a microelectrode technique.
    Advances in experimental medicine and biology, 1998, Volume: 438

    Topics: Acetylcysteine; Animals; Eye Proteins; Female; Male; Microelectrodes; Mucus; Potentiometry; Rats; Rats, Wistar; Tears

1998
Effects of mucokinetic drugs on rheological properties of reconstituted human nasal mucus.
    Archives of otolaryngology--head & neck surgery, 1999, Volume: 125, Issue:1

    Topics: Acetylcysteine; Adolescent; Adult; Child; Deoxyribonucleases; Expectorants; Female; Humans; Male; Middle Aged; Mucus; Nasal Mucosa; Polyethylene Glycols; Rheology; Sinusitis; Sodium Bicarbonate; Viscosity

1999
Atelectasis and mucus plugging in spinal cord injury: case report and therapeutic approaches.
    The journal of spinal cord medicine, 2001,Winter, Volume: 24, Issue:4

    Topics: Acetylcysteine; Airway Obstruction; Bronchodilator Agents; Bronchoscopy; Combined Modality Therapy; Follow-Up Studies; Humans; Male; Middle Aged; Mucus; Pulmonary Atelectasis; Radiography; Respiratory Therapy; Spinal Cord Injuries

2001
The effect of N-acetyl-L-cysteine on the viscosity of ileal neobladder mucus.
    World journal of urology, 2002, Volume: 20, Issue:1

    Topics: Acetylcysteine; Expectorants; Humans; Ileum; Mucus; Surgically-Created Structures; Urinary Bladder; Urine; Viscosity

2002
NEW MUCOLYTIC AGENTS FOR SPUTUM LIQUEFACTION.
    Postgraduate medicine, 1964, Volume: 36

    Topics: Acetylcysteine; Asthma; Bronchial Diseases; Cysteine; Cystic Fibrosis; Expectorants; Fibrin; Humans; Lung Diseases; Mucus; Sputum; Toxicology

1964
INHALATION THERAPY.
    Canadian Medical Association journal, 1965, Jan-09, Volume: 92

    Topics: Acetylcysteine; Anti-Bacterial Agents; Bronchial Spasm; Cysteine; Drug Therapy; Epinephrine; Equipment and Supplies; Humans; Hypoxia; Isoproterenol; Mucus; Oxygen Inhalation Therapy; Phenylephrine; Propylene Glycols; Respiratory Therapy; Respiratory Tract Diseases

1965
A NEW MUCOLYTIC AGENT AS A THERAPEUTIC ADJUNCT IN NASAL SINUSITIS.
    Eye, ear, nose & throat monthly, 1965, Volume: 44

    Topics: Acetylcysteine; Cysteine; Expectorants; Humans; Mucus; Nose; Sinusitis; Therapeutic Irrigation; Toxicology

1965
Effects of laxative and N-acetylcysteine on mucus accumulation, bacterial load, transit, and inflammation in the cystic fibrosis mouse small intestine.
    American journal of physiology. Gastrointestinal and liver physiology, 2007, Volume: 293, Issue:3

    Topics: Acetylcysteine; Animals; Bacteria; Body Weight; Cathartics; Cystic Fibrosis; Disease Models, Animal; Expectorants; Gastric Emptying; Gastrointestinal Transit; Gene Expression Regulation; Immunity, Innate; Inflammation; Intestine, Small; Mice; Mice, Inbred CFTR; Mucus; Polyethylene Glycols; RNA, Bacterial; RNA, Ribosomal, 16S

2007
Hydrophobicity of mucosal surface and its relationship to gut barrier function.
    Shock (Augusta, Ga.), 2008, Volume: 29, Issue:3

    Topics: Acetylcysteine; Animals; Expectorants; Hydrophobic and Hydrophilic Interactions; Intestinal Mucosa; Ischemia; Male; Mucus; Permeability; Rats; Rats, Sprague-Dawley

2008
Plastic bronchitis as an unusual cause of mucus plugging in cystic fibrosis.
    Pediatric pulmonology, 2009, Volume: 44, Issue:9

    Topics: Acetylcysteine; Administration, Inhalation; Bronchitis; Child, Preschool; Cystic Fibrosis; Expectorants; Humans; Male; Mucus; Pulmonary Disease, Chronic Obstructive

2009
Gastroprotective effect of barbatusin and 3-beta-hydroxy-3-deoxibarbatusin, quinonoid diterpenes isolated from Plectranthus grandis, in ethanol-induced gastric lesions in mice.
    Journal of ethnopharmacology, 2010, Feb-17, Volume: 127, Issue:3

    Topics: Acetylcysteine; Animals; Anti-Ulcer Agents; Antioxidants; Capsaicin; Disease Models, Animal; Diterpenes; Ethanol; Gastric Mucosa; Glyburide; Indomethacin; Male; Mice; Mucus; NG-Nitroarginine Methyl Ester; Phytotherapy; Plant Extracts; Plant Leaves; Plectranthus; Quinones; Stomach; Stomach Ulcer; Sulfhydryl Compounds; Thiobarbiturates

2010
Loss of the intestinal mucus layer in the normal rat causes gut injury but not toxic mesenteric lymph nor lung injury.
    Shock (Augusta, Ga.), 2010, Volume: 34, Issue:5

    Topics: Acetylcysteine; Acute Lung Injury; Animals; Bacterial Translocation; Evans Blue; Expectorants; Hydrophobic and Hydrophilic Interactions; Ileum; Intestinal Mucosa; Ligation; Lung; Lymph; Male; Mesentery; Models, Biological; Mucus; Pancreas; Peptide Hydrolases; Permeability; Rats; Rats, Sprague-Dawley; Respiratory Burst

2010
Dexamethasone and N-acetyl-cysteine attenuate Pseudomonas aeruginosa-induced mucus expression in human airways.
    Pulmonary pharmacology & therapeutics, 2011, Volume: 24, Issue:2

    Topics: Acetylcysteine; Anti-Inflammatory Agents; Cell Line; Dexamethasone; Dose-Response Relationship, Drug; Epithelial Cells; Expectorants; Gene Expression Regulation; Humans; Mucin 5AC; Mucus; Polymerase Chain Reaction; Pseudomonas aeruginosa; Respiratory Mucosa

2011
Airway mucus function and dysfunction.
    The New England journal of medicine, 2011, 03-10, Volume: 364, Issue:10

    Topics: Acetylcysteine; Humans; Insufflation; Lung Diseases; Mucus; Respiratory Physiological Phenomena; Tracheostomy

2011
Effects of oral treatment with N-acetylcysteine on the viscosity of intrauterine mucus and endometrial function in estrous mares.
    Theriogenology, 2012, Oct-01, Volume: 78, Issue:6

    Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Body Fluids; Breeding; Endometritis; Endometrium; Female; Horse Diseases; Horses; Immunohistochemistry; Ki-67 Antigen; Lectins; Mucus; Uterus; Viscosity

2012
A formulation for in situ lysis of mucin secreted in pseudomyxoma peritonei.
    International journal of cancer, 2014, Jan-15, Volume: 134, Issue:2

    Topics: Acetylcysteine; Animals; Bromelains; Drug Combinations; Expectorants; Male; Mucins; Mucus; Peritoneal Neoplasms; Pseudomyxoma Peritonei; Rats; Rats, Nude

2014
Enhanced oral delivery of paclitaxel using acetylcysteine functionalized chitosan-vitamin E succinate nanomicelles based on a mucus bioadhesion and penetration mechanism.
    Molecular pharmaceutics, 2013, Sep-03, Volume: 10, Issue:9

    Topics: Acetylcysteine; Animals; Chitosan; Drug Carriers; Micelles; Mucus; Paclitaxel; Rats; Rats, Sprague-Dawley; Spectrometry, X-Ray Emission; Thermogravimetry; Vitamin E

2013
Nebulised N-acetylcysteine used in acute tracheostoma obstruction.
    The Journal of laryngology and otology, 2014, Volume: 128, Issue:12

    Topics: Acetylcysteine; Aged; Airway Obstruction; Drug Therapy, Combination; Expectorants; Female; Humans; Laryngectomy; Mucus; Nebulizers and Vaporizers; Sodium Chloride; Tracheostomy

2014
Oxidation increases mucin polymer cross-links to stiffen airway mucus gels.
    Science translational medicine, 2015, Feb-25, Volume: 7, Issue:276

    Topics: Acetylcysteine; Animals; Biomechanical Phenomena; Cross-Linking Reagents; Cystic Fibrosis; Disulfides; DNA; Elasticity; Expectorants; Galactose; Gels; Humans; Lung; Mice, Inbred C57BL; Mucins; Mucus; Oxidation-Reduction; Oxidative Stress; Polymers; Reducing Agents; Sputum; Sulfhydryl Compounds

2015
Tracing molecular and structural changes upon mucolysis with N-acetyl cysteine in human airway mucus.
    International journal of pharmaceutics, 2017, Nov-30, Volume: 533, Issue:2

    Topics: Acetylcysteine; Freeze Drying; Humans; Microscopy, Electron, Scanning; Mucus; Respiratory Mucosa; Rheology; Spectrum Analysis, Raman

2017
An Improved Inhaled Mucolytic to Treat Airway Muco-obstructive Diseases.
    American journal of respiratory and critical care medicine, 2019, 01-15, Volume: 199, Issue:2

    Topics: Acetylcysteine; Animals; Asthma; Cystic Fibrosis; Disease Models, Animal; Dithiothreitol; Expectorants; Humans; In Vitro Techniques; Male; Mice; Mucociliary Clearance; Mucus; Pulmonary Disease, Chronic Obstructive

2019
Jejunal absorption of aprepitant from nanosuspensions: Role of particle size, prandial state and mucus layer.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2018, Volume: 132

    Topics: Acetylcysteine; Administration, Oral; Animals; Aprepitant; Biological Availability; Chemistry, Pharmaceutical; Intestinal Absorption; Intestinal Mucosa; Jejunum; Male; Mucus; Nanoparticles; Particle Size; Rats; Rats, Wistar; Solubility; Suspensions

2018
Spray-drying of inhalable, multifunctional formulations for the treatment of biofilms formed in cystic fibrosis.
    Journal of controlled release : official journal of the Controlled Release Society, 2019, 11-28, Volume: 314

    Topics: Acetylcysteine; Administration, Inhalation; Animals; Anti-Bacterial Agents; Azithromycin; Biofilms; Ciprofloxacin; Cystic Fibrosis; Drug Stability; Drug Storage; Expectorants; Horses; Mucus; Particle Size; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin

2019
Improved chemosensitivity following mucolytic therapy in patient-derived models of mucinous appendix cancer.
    Translational research : the journal of laboratory and clinical medicine, 2021, Volume: 229

    Topics: Acetylcysteine; Adenocarcinoma, Mucinous; Animals; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Bromelains; Drug Resistance, Neoplasm; Humans; Mice, Nude; Mucus; Peritoneal Neoplasms; Rats, Nude; Tissue Culture Techniques; Xenograft Model Antitumor Assays

2021
Spray-dried multidrug particles for pulmonary co-delivery of antibiotics with N-acetylcysteine and curcumin-loaded PLGA-nanoparticles.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2020, Volume: 157

    Topics: Acetylcysteine; Administration, Inhalation; Anti-Bacterial Agents; Anti-Inflammatory Agents; Azithromycin; Ciprofloxacin; Curcumin; Cytokines; Drug Carriers; Drug Combinations; Drug Compounding; Expectorants; Freeze Drying; Humans; Inflammation Mediators; Macrophages; Microbial Viability; Mucus; Nanoparticles; Permeability; Polylactic Acid-Polyglycolic Acid Copolymer; Pseudomonas aeruginosa; Pseudomonas Infections; THP-1 Cells; Tobramycin

2020
Engineered lipid liquid crystalline nanoparticles as an inhaled nanoplatform for mucus penetration enhancement.
    Drug delivery and translational research, 2023, Volume: 13, Issue:11

    Topics: Acetylcysteine; Drug Carriers; Lipids; Mucins; Mucus; Nanoparticles

2023