Compounds > griseolic acid
Page last updated: 2024-09-03

griseolic acid and 1-methyl-3-isobutylxanthine

griseolic acid has been researched along with 1-methyl-3-isobutylxanthine in 3 studies

Compound Research Comparison

Studies
(griseolic acid)		Trials
(griseolic acid)		Recent Studies (post-2010)
(griseolic acid)		Studies
(1-methyl-3-isobutylxanthine)		Trials
(1-methyl-3-isobutylxanthine)		Recent Studies (post-2010) (1-methyl-3-isobutylxanthine)
19005,1485279

Protein Interaction Comparison

ProteinTaxonomygriseolic acid (IC50)1-methyl-3-isobutylxanthine (IC50)
Chain A, High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7AHomo sapiens (human)8.1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)31
Chain A, Phosphodiesterase 9AHomo sapiens (human)500
Chain A, Class I phosphodiesterase PDEB1Leishmania major580
Chain A, High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8AHomo sapiens (human)698
Chain A, cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)40
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9AHomo sapiens (human)117.2
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9AHomo sapiens (human)117.2
Phosphodiesterase Bos taurus (cattle)9.9
cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)4
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)3.1667
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A Bos taurus (cattle)9.9
Adenosine receptor A1Rattus norvegicus (Norway rat)7
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1AHomo sapiens (human)3.4
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BBos taurus (cattle)9.9
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BHomo sapiens (human)3.4
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BRattus norvegicus (Norway rat)0.1
cGMP-inhibited 3',5'-cyclic phosphodiesterase BHomo sapiens (human)0.242
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1CHomo sapiens (human)3.4
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)7
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1CRattus norvegicus (Norway rat)0.1
Phosphodiesterase Rattus norvegicus (Norway rat)0.1

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ito, H; Kajinuma, H; Makino, H; Suzuki, T; Yamazaki, M; Yoshida, S1
Fukami, S; Iijima, Y; Kaneko, M; Kiuchi, Y; Mishima, H; Yamazaki, M; Yasumoto, T; Yokoyama, T1
Hashimoto, N; Kanatsuka, A; Makino, H; Yamazaki, M; Yoshida, S1

Other Studies

3 other study(ies) available for griseolic acid and 1-methyl-3-isobutylxanthine

ArticleYear
The role of insulin-sensitive phosphodiesterase in insulin action.
    Advances in second messenger and phosphoprotein research, 1992, Volume: 25

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adipose Tissue; Animals; Cyclic AMP; Dose-Response Relationship, Drug; Glycerol; In Vitro Techniques; Insulin; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Tritium

1992
Griseolic acid, a cAMP phosphodiesterase inhibitor, and its ester: increase in cellular cAMP levels and reduction of intraocular pressure.
    Advances in second messenger and phosphoprotein research, 1990, Volume: 24

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Animals; Cattle; Cell Line; Cyclic AMP; Esters; Fibroblasts; Intraocular Pressure; Mice; Molecular Structure; Rabbits; Structure-Activity Relationship

1990
Effects of the new phosphodiesterase inhibitor griseolic acid on insulin release in rat pancreatic islets.
    Arzneimittel-Forschung, 1990, Volume: 40, Issue:10

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Animals; Calcium; Calcium Radioisotopes; Cyclic AMP; In Vitro Techniques; Insulin; Islets of Langerhans; Male; Rats; Rats, Inbred Strains

1990