Page last updated: 2024-08-25

grepafloxacin and sparfloxacin

grepafloxacin has been researched along with sparfloxacin in 28 studies

Research

Studies (28)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	10 (35.71)	18.2507
2000's	16 (57.14)	29.6817
2010's	2 (7.14)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Sasabe, H; Sugiyama, Y; Tsuji, A	1
Nezu, JI; Ohashi, R; Oku, A; Sai, Y; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H	1
Kido, Y; Koizumi, S; Naruhashi, K; Ohnari, A; Sai, Y; Shima, Y; Tamai, I; Tsuji, A; Yamashita, J	1
Inoue, N; Muraoka, H; Naruhashi, K; Sai, Y; Suzuki, N; Tamai, I; Tsuji, A	1
Cai, SH; Hasegawa, T; Kitaichi, K; Nadai, M; Takagi, K; Tatsumi, Y; Wang, L; Yoshizumi, H; Zhao, YL	1
Cavalli, A; De Ponti, F; Poluzzi, E; Recanatini, M	1
Keserü, GM	1
Li, J; Rajamani, R; Reynolds, CH; Tounge, BA	1
Nagashima, R; Nishikawa, T; Tobita, M	1
Morgan-Linnell, SK; Zechiedrich, L	1
Jia, L; Sun, H	1
Caron, G; Ermondi, G; Visentin, S	1
Imai, YN; Oiki, S; Ryu, S	1
Blaskovich, MAT; Pham, TDM; Ziora, ZM	1
Hammerschlag, MR; Montalban, G; Roblin, PM	1
Cartwright, FD; Kenny, GE	1
Hecht, DW; Wexler, HM	1
Goldstein, EJ	1
Barry, AL; Brown, SD; Fuchs, PC	1
Heisig, P; Jones, ME; Klootwijk, M; Schmitz, FJ; Verhoef, J; Visser, MR	1
Bébéar, C; Bébéar, CM; Leblanc, F; Renaudin, H; Schaeverbeke, T	1
Hajime, N; Kamberi, M; Kamberi, P; Nakamura, K; Nakano, S; Uemura, N	1
Hooper, DC	2
Amsterdam, D; Hardy, D; Mandell, LA; Rotstein, C	1
Fraser, S; Mair, D; Patmore, L; Templeton, A	1
Anderson, ME; Mazur, A; Roden, DM; Yang, T	1
Bermejo, MV; Garrigues, TM; Merino, V; Montalar-Montero, M; Nalda-Molina, R; Rodríguez-Ibáñez, M	1

Reviews

4 review(s) available for grepafloxacin and sparfloxacin

Article	Year
Quinolone antibiotics. MedChemComm, 2019, Oct-01, Volume: 10, Issue:10 Topics:	2019
Possible role for the new fluoroquinolones (levofloxacin, grepafloxacin, trovafloxacin, clinafloxacin, sparfloxacin, and DU-6859a) in the treatment of anaerobic infections: review of current information on efficacy and safety. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1996, Volume: 23 Suppl 1 Topics: Anti-Infective Agents; Bacteria, Anaerobic; Bacterial Infections; Fluoroquinolones; Humans; Levofloxacin; Naphthyridines; Ofloxacin; Piperazines; Quinolones; Safety; Syndrome	1996
New uses for new and old quinolones and the challenge of resistance. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2000, Volume: 30, Issue:2 Topics: Anti-Infective Agents; Bacterial Infections; Drug Resistance, Microbial; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Piperazines; Respiratory Tract Infections; Sensitivity and Specificity; Sexually Transmitted Diseases; Urinary Tract Infections	2000
The fluoroquinolones after ciprofloxacin and ofloxacin. Current clinical topics in infectious diseases, 2000, Volume: 20 Topics: Anti-Infective Agents; Bacterial Infections; Fluoroquinolones; Humans; Naphthyridines; Ofloxacin; Piperazines; Respiratory Tract Infections; Sexually Transmitted Diseases, Bacterial; Skin Diseases, Bacterial; Urinary Tract Infections	2000

Other Studies

24 other study(ies) available for grepafloxacin and sparfloxacin

Article	Year
Carrier-mediated mechanism for the biliary excretion of the quinolone antibiotic grepafloxacin and its glucuronide in rats. The Journal of pharmacology and experimental therapeutics, 1998, Volume: 284, Issue:3 Topics: Animals; Anti-Infective Agents; Bile; Biological Transport, Active; Fluoroquinolones; Glucuronates; Glutathione; Hyperbilirubinemia; Male; Piperazines; Quinolones; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley	1998
Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:2 Topics: Biological Transport, Active; Carnitine; Carrier Proteins; Cations; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Humans; Hydrogen-Ion Concentration; Kidney; Membrane Proteins; Organic Cation Transport Proteins; Sodium; Solute Carrier Family 22 Member 5; Stereoisomerism	1999
Limited distribution of new quinolone antibacterial agents into brain caused by multiple efflux transporters at the blood-brain barrier. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 295, Issue:1 Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Anti-Infective Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Bicarbonates; Blood-Brain Barrier; Brain; Fluoroquinolones; HL-60 Cells; Humans; Mice; Multidrug Resistance-Associated Proteins; Perfusion; Piperazines; Rats	2000
Active intestinal secretion of new quinolone antimicrobials and the partial contribution of P-glycoprotein. The Journal of pharmacy and pharmacology, 2001, Volume: 53, Issue:5 Topics: Animals; Anti-Infective Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Cell Line; Fluoroquinolones; Humans; Intestinal Absorption; Male; Mice; Rats; Rats, Sprague-Dawley	2001
Possible involvement of P-glycoprotein in the biliary excretion of grepafloxacin. Clinical and experimental pharmacology & physiology, 2002, Volume: 29, Issue:3 Topics: Animals; Anti-Infective Agents; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile; Biliary Tract; Doxorubicin; Drug Resistance, Neoplasm; Fluoroquinolones; Leukemia P388; Male; Mice; Piperazines; Quinolones; Rats; Rats, Wistar; Tumor Cells, Cultured	2002
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers. Journal of medicinal chemistry, 2002, Aug-29, Volume: 45, Issue:18 Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go-Go Potassium Channels; Long QT Syndrome; Models, Molecular; Molecular Conformation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship	2002
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship	2003
A two-state homology model of the hERG K+ channel: application to ligand binding. Bioorganic & medicinal chemistry letters, 2005, Mar-15, Volume: 15, Issue:6 Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Ligands; Models, Biological; Models, Molecular; Potassium Channels, Voltage-Gated; Protein Binding; Protein Conformation	2005
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors. Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11 Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated	2005
Contributions of the combined effects of topoisomerase mutations toward fluoroquinolone resistance in Escherichia coli. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:11 Topics: DNA Topoisomerases; Drug Resistance, Bacterial; Escherichia coli; Fluoroquinolones; Microbial Sensitivity Tests; Mutation	2007
Support vector machines classification of hERG liabilities based on atom types. Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11 Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve	2008
GRIND-based 3D-QSAR and CoMFA to investigate topics dominated by hydrophobic interactions: the case of hERG K+ channel blockers. European journal of medicinal chemistry, 2009, Volume: 44, Issue:5 Topics: Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Potassium Channel Blockers; Quantitative Structure-Activity Relationship	2009
The synergic modeling for the binding of fluoroquinolone antibiotics to the hERG potassium channel. Bioorganic & medicinal chemistry letters, 2013, Jul-01, Volume: 23, Issue:13 Topics: Anti-Bacterial Agents; Binding Sites; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fluoroquinolones; Humans; Models, Molecular; Potassium Channel Blockers; Structure-Activity Relationship	2013
In vitro activities of OPC-17116, a new quinolone; ofloxacin; and sparfloxacin against Chlamydia pneumoniae. Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:6 Topics: Anti-Infective Agents; Chlamydophila pneumoniae; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Piperazines; Quinolones	1994
Susceptibilities of Mycoplasma hominis, Mycoplasma pneumoniae, and Ureaplasma urealyticum to a new quinolone, OPC 17116. Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:8 Topics: Anti-Infective Agents; Fluoroquinolones; Microbial Sensitivity Tests; Mycoplasma; Mycoplasma pneumoniae; Ofloxacin; Piperazines; Quinolones; Ureaplasma urealyticum	1993
In vitro susceptibility of anaerobes to quinolones in the United States. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1996, Volume: 23 Suppl 1 Topics: Anti-Infective Agents; Bacteria, Anaerobic; Culture Media; Drug Resistance, Microbial; Evaluation Studies as Topic; Fluoroquinolones; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Piperazines; Quinolones; United States	1996
Is Escherichia coli ATCC 25922 useful for monitoring broth microdilution tests of fluoroquinolones? The Journal of antimicrobial chemotherapy, 1997, Volume: 39, Issue:4 Topics: Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Escherichia coli; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Piperazines; Quinolones; Reproducibility of Results	1997
Comparative activities of clinafloxacin, grepafloxacin, levofloxacin, moxifloxacin, ofloxacin, sparfloxacin, and trovafloxacin and nonquinolones linozelid, quinupristin-dalfopristin, gentamicin, and vancomycin against clinical isolates of ciprofloxacin-re Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:2 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gentamicins; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Piperazines; Quinolines; Quinolones; Staphylococcus aureus; Vancomycin; Virginiamycin	1999
In-vitro activity of grepafloxacin, a new fluoroquinolone, against mycoplasmas. The Journal of antimicrobial chemotherapy, 1999, Volume: 43, Issue:5 Topics: Anti-Infective Agents; Ciprofloxacin; Doxycycline; Erythromycin; Fluoroquinolones; Microbial Sensitivity Tests; Mycoplasma; Ofloxacin; Piperazines; Ureaplasma urealyticum	1999
Determination of sparfloxacin in plasma and urine by a simple and rapid liquid chromatographic method. Therapeutic drug monitoring, 1999, Volume: 21, Issue:4 Topics: Anti-Infective Agents; Antitubercular Agents; Chromatography, High Pressure Liquid; Chromatography, Liquid; Drug Monitoring; Fluoroquinolones; Humans; Piperazines; Spectrophotometry, Ultraviolet	1999
Comparative in vitro activities of ciprofloxacin, gemifloxacin, grepafloxacin, moxifloxacin, ofloxacin, sparfloxacin, trovafloxacin, and other antimicrobial agents against bloodstream isolates of gram-positive cocci. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:3 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Bacteremia; Ciprofloxacin; Fluoroquinolones; Gemifloxacin; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Humans; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Piperazines; Quinolines	2000
Effects of sparfloxacin, grepafloxacin, moxifloxacin, and ciprofloxacin on cardiac action potential duration. European journal of pharmacology, 2000, Oct-20, Volume: 406, Issue:3 Topics: Action Potentials; Animals; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Dogs; Female; Fluoroquinolones; Heart; Male; Moxifloxacin; Piperazines; Quinolines; Time Factors	2000
Potassium current antagonist properties and proarrhythmic consequences of quinolone antibiotics. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 296, Issue:3 Topics: 4-Quinolones; Animals; Anti-Infective Agents; Arrhythmias, Cardiac; Aza Compounds; Cation Transport Proteins; DNA-Binding Proteins; Electrocardiography; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fluoroquinolones; Gatifloxacin; Long QT Syndrome; Mice; Models, Animal; Moxifloxacin; Patch-Clamp Techniques; Piperazines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quinolines; Rabbits; Trans-Activators; Tumor Cells, Cultured	2001
Transintestinal secretion of ciprofloxacin, grepafloxacin and sparfloxacin: in vitro and in situ inhibition studies. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2003, Volume: 55, Issue:2 Topics: Animals; Anti-Infective Agents; Biological Availability; Caco-2 Cells; Chromatography, High Pressure Liquid; Ciprofloxacin; Drug Carriers; Fluoroquinolones; Humans; In Vitro Techniques; Intestinal Absorption; Male; Models, Biological; Piperazines; Rats; Rats, Wistar	2003