Page last updated: 2024-08-25

grepafloxacin and moxifloxacin

grepafloxacin has been researched along with moxifloxacin in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.00)18.2507
2000's17 (68.00)29.6817
2010's6 (24.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Cavalli, A; De Ponti, F; Poluzzi, E; Recanatini, M1
Keserü, GM1
Li, J; Rajamani, R; Reynolds, CH; Tounge, BA1
Nagashima, R; Nishikawa, T; Tobita, M1
Morgan-Linnell, SK; Zechiedrich, L1
Jia, L; Sun, H1
Caron, G; Ermondi, G; Visentin, S1
Larruskain, J; Montes, M; Orden, B; Perez-Trallero, E; Tamayo, E1
Brillault, J; Couet, W; De Castro, WV1
Anquetin, G; Biot, C; Dive, D; Dubar, F; Khalife, J; Pradines, B1
Sen, S; Sinha, N1
Imai, YN; Oiki, S; Ryu, S1
Blaskovich, MAT; Pham, TDM; Ziora, ZM1
Dana, S; Dhar, SK; Gurung, SK; Kumar, S; Mondal, N; Mukhopadhyay, P; Valissery, P1
Heisig, P; Jones, ME; Klootwijk, M; Schmitz, FJ; Verhoef, J; Visser, MR1
Amsterdam, D; Hardy, D; Mandell, LA; Rotstein, C1
Bjarnason, J; Blondeau, JM; Laskowski, R; Stewart, C1
Fraser, S; Mair, D; Patmore, L; Templeton, A1
Esposito, S; Ianniello, F; Noviello, S1
Doern, GV; Ernst, EJ; Klepser, ME; Petzold, CR; Rhomberg, P1
Anderson, ME; Mazur, A; Roden, DM; Yang, T1
Cox, BF; Gintant, GA; Limberis, JT; McDermott, JS; Wegner, CD1
Johnson, AP; Livermore, DM; Warner, M1
Dalhoff, A; Shalit, I1
Brillault, J; Couet, W; Gobin, P; Gontijo, AV; Grégoire, N; Lamarche, I; Marchand, S1

Reviews

2 review(s) available for grepafloxacin and moxifloxacin

ArticleYear
Quinolone antibiotics.
    MedChemComm, 2019, Oct-01, Volume: 10, Issue:10

    Topics:

2019
Immunomodulatory effects of quinolones.
    The Lancet. Infectious diseases, 2003, Volume: 3, Issue:6

    Topics: Adjuvants, Immunologic; Animals; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Clinical Trials as Topic; Cytokines; Fluoroquinolones; Humans; Immune System; Models, Animal; Moxifloxacin; Naphthyridines; Ofloxacin; Piperazines; Quinolines

2003

Other Studies

23 other study(ies) available for grepafloxacin and moxifloxacin

ArticleYear
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers.
    Journal of medicinal chemistry, 2002, Aug-29, Volume: 45, Issue:18

    Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go-Go Potassium Channels; Long QT Syndrome; Models, Molecular; Molecular Conformation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2002
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2003
A two-state homology model of the hERG K+ channel: application to ligand binding.
    Bioorganic & medicinal chemistry letters, 2005, Mar-15, Volume: 15, Issue:6

    Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Ligands; Models, Biological; Models, Molecular; Potassium Channels, Voltage-Gated; Protein Binding; Protein Conformation

2005
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Contributions of the combined effects of topoisomerase mutations toward fluoroquinolone resistance in Escherichia coli.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:11

    Topics: DNA Topoisomerases; Drug Resistance, Bacterial; Escherichia coli; Fluoroquinolones; Microbial Sensitivity Tests; Mutation

2007
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve

2008
GRIND-based 3D-QSAR and CoMFA to investigate topics dominated by hydrophobic interactions: the case of hERG K+ channel blockers.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:5

    Topics: Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Potassium Channel Blockers; Quantitative Structure-Activity Relationship

2009
Prevalence and clonal characterization of Streptococcus pyogenes clinical isolates with reduced fluoroquinolone susceptibility in Spain.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1

    Topics: Adult; Anti-Bacterial Agents; Child; Drug Resistance, Bacterial; Female; Fluoroquinolones; Genes, Bacterial; Humans; Male; Microbial Sensitivity Tests; Mutation; Prospective Studies; Spain; Streptococcal Infections; Streptococcus pyogenes

2010
Relative contributions of active mediated transport and passive diffusion of fluoroquinolones with various lipophilicities in a Calu-3 lung epithelial cell model.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1

    Topics: Absorption; Anti-Bacterial Agents; ATP Binding Cassette Transporter, Subfamily B; Biological Transport, Active; Cell Line; Cell Membrane Permeability; Cyclosporins; Diffusion; Drug Interactions; Drug Resistance, Bacterial; Epithelial Cells; Fluoroquinolones; Kinetics; Lipids; Lung

2010
Enhancement of the antimalarial activity of ciprofloxacin using a double prodrug/bioorganometallic approach.
    Journal of medicinal chemistry, 2009, Dec-24, Volume: 52, Issue:24

    Topics: Aminoquinolines; Antimalarials; Ciprofloxacin; Ferrous Compounds; Metallocenes; Plasmodium falciparum; Prodrugs

2009
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
The synergic modeling for the binding of fluoroquinolone antibiotics to the hERG potassium channel.
    Bioorganic & medicinal chemistry letters, 2013, Jul-01, Volume: 23, Issue:13

    Topics: Anti-Bacterial Agents; Binding Sites; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fluoroquinolones; Humans; Models, Molecular; Potassium Channel Blockers; Structure-Activity Relationship

2013
Synthesis of Novel Ciprofloxacin-Based Hybrid Molecules toward Potent Antimalarial Activity.
    ACS medicinal chemistry letters, 2020, Jul-09, Volume: 11, Issue:7

    Topics:

2020
Comparative activities of clinafloxacin, grepafloxacin, levofloxacin, moxifloxacin, ofloxacin, sparfloxacin, and trovafloxacin and nonquinolones linozelid, quinupristin-dalfopristin, gentamicin, and vancomycin against clinical isolates of ciprofloxacin-re
    Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:2

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gentamicins; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Piperazines; Quinolines; Quinolones; Staphylococcus aureus; Vancomycin; Virginiamycin

1999
Comparative in vitro activities of ciprofloxacin, gemifloxacin, grepafloxacin, moxifloxacin, ofloxacin, sparfloxacin, trovafloxacin, and other antimicrobial agents against bloodstream isolates of gram-positive cocci.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:3

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Bacteremia; Ciprofloxacin; Fluoroquinolones; Gemifloxacin; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Humans; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Piperazines; Quinolines

2000
Comparative in vitro activity of gatifloxacin, grepafloxacin, levofloxacin, moxifloxacin and trovafloxacin against 4151 Gram-negative and Gram-positive organisms.
    International journal of antimicrobial agents, 2000, Volume: 14, Issue:1

    Topics: Anti-Infective Agents; Aza Compounds; Drug Resistance, Microbial; Fluoroquinolones; Gatifloxacin; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Piperazines; Quinolines

2000
Effects of sparfloxacin, grepafloxacin, moxifloxacin, and ciprofloxacin on cardiac action potential duration.
    European journal of pharmacology, 2000, Oct-20, Volume: 406, Issue:3

    Topics: Action Potentials; Animals; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Dogs; Female; Fluoroquinolones; Heart; Male; Moxifloxacin; Piperazines; Quinolines; Time Factors

2000
Bactericidal activity of moxifloxacin compared to grepafloxacin and clarithromycin against Streptococcus pneumoniae and Streptococcus pyogenes investigated using an in vitro pharmacodynamic model.
    Journal of chemotherapy (Florence, Italy), 2000, Volume: 12, Issue:6

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Clarithromycin; Erythromycin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Models, Biological; Moxifloxacin; Penicillin Resistance; Piperazines; Quinolines; Streptococcus pneumoniae; Streptococcus pyogenes; Time Factors

2000
Comparative bactericidal activities of ciprofloxacin, clinafloxacin, grepafloxacin, levofloxacin, moxifloxacin, and trovafloxacin against Streptococcus pneumoniae in a dynamic in vitro model.
    Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:3

    Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Colony Count, Microbial; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Models, Biological; Moxifloxacin; Naphthyridines; Ofloxacin; Piperazines; Quinolines; Streptococcus pneumoniae; Time Factors

2001
Potassium current antagonist properties and proarrhythmic consequences of quinolone antibiotics.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 296, Issue:3

    Topics: 4-Quinolones; Animals; Anti-Infective Agents; Arrhythmias, Cardiac; Aza Compounds; Cation Transport Proteins; DNA-Binding Proteins; Electrocardiography; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fluoroquinolones; Gatifloxacin; Long QT Syndrome; Mice; Models, Animal; Moxifloxacin; Patch-Clamp Techniques; Piperazines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quinolines; Rabbits; Trans-Activators; Tumor Cells, Cultured

2001
The canine Purkinje fiber: an in vitro model system for acquired long QT syndrome and drug-induced arrhythmogenesis.
    Journal of cardiovascular pharmacology, 2001, Volume: 37, Issue:5

    Topics: Action Potentials; Animals; Anti-Infective Agents; Arrhythmias, Cardiac; Aza Compounds; Cisapride; Dogs; Erythromycin; Female; Fluoroquinolones; Imidazoles; In Vitro Techniques; Indoles; Long QT Syndrome; Male; Models, Biological; Moxifloxacin; Perfusion; Piperazines; Purkinje Fibers; Quinolines; Sotalol; Swine; Torsades de Pointes

2001
Activity of moxifloxacin and other quinolones against pneumococci resistant to first-line agents, or with high-level ciprofloxacin resistance.
    International journal of antimicrobial agents, 2001, Volume: 17, Issue:5

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Drug Resistance, Microbial; Drug Resistance, Multiple; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Piperazines; Quinolines; Streptococcus pneumoniae

2001
Biopharmaceutical characterization of nebulized antimicrobial agents in rats: 1. Ciprofloxacin, moxifloxacin, and grepafloxacin.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:7

    Topics: Administration, Inhalation; Aerosols; Animals; Anti-Bacterial Agents; Biopharmaceutics; Bronchoalveolar Lavage Fluid; Cell Line; Ciprofloxacin; Fluoroquinolones; Humans; Macrophages, Alveolar; Male; Moxifloxacin; Piperazines; Rats; Rats, Sprague-Dawley; Urea

2014