Page last updated: 2024-08-25

grepafloxacin and clarithromycin

grepafloxacin has been researched along with clarithromycin in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (30.77)18.2507
2000's7 (53.85)29.6817
2010's2 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Keserü, GM1
Nagashima, R; Nishikawa, T; Tobita, M1
Jia, L; Sun, H1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Dencer, C; Felmingham, D; Ridgway, GL; Robbins, MJ; Salman, H1
Frimpong, EK; Honda, T; Voravuthikunchai, SP; Yoh, M1
Churchyard, GA; Dylewski, JS; Hagberg, L; Moola, S; Sedani, S; Staley, H1
Langan, CE; Marr, C; McIvor, A; Peirzchala, W; Smakal, M; Staley, H; Vogel, F; Zuck, P1
Ballow, CH; Forrest, A; Hyatt, JM; Peloquin, CA; Sands, MF; Schentag, JJ; Tran, JQ1
Esposito, S; Ianniello, F; Noviello, S1
Asherov, J; Dan, M; Poch, F1
Cynamon, MH; Sklaney, M; Yeo, AE1

Trials

4 trial(s) available for grepafloxacin and clarithromycin

ArticleYear
A multicenter study of grepafloxacin and clarithromycin in the treatment of patients with community-acquired pneumonia.
    Chest, 1999, Volume: 116, Issue:4

    Topics: Adult; Aged; Anti-Infective Agents; Clarithromycin; Community-Acquired Infections; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Fluoroquinolones; Humans; Male; Middle Aged; Piperazines; Pneumonia, Bacterial; Prospective Studies; Treatment Outcome

1999
Randomized, double-blind study of short-course (5 day) grepafloxacin versus 10 day clarithromycin in patients with acute bacterial exacerbations of chronic bronchitis.
    The Journal of antimicrobial chemotherapy, 1999, Volume: 44, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Bronchitis; Clarithromycin; Double-Blind Method; Female; Fluoroquinolones; Humans; Male; Middle Aged; Piperazines

1999
Comparison of the abilities of grepafloxacin and clarithromycin to eradicate potential bacterial pathogens from the sputa of patients with chronic bronchitis: influence of pharmacokinetic and pharmacodynamic variables.
    The Journal of antimicrobial chemotherapy, 2000, Volume: 45

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Bronchitis; Chronic Disease; Clarithromycin; Female; Fluoroquinolones; Haemophilus; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Models, Biological; Piperazines; Serum Bactericidal Test; Sputum

2000
Crossover assessment of serum bactericidal activity of grepafloxacin, ofloxacin and clarithromycin against respiratory pathogens after oral administration to healthy volunteers.
    International journal of antimicrobial agents, 2001, Volume: 17, Issue:6

    Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Blood Bactericidal Activity; Clarithromycin; Cross-Over Studies; Female; Fluoroquinolones; Haemophilus influenzae; Humans; In Vitro Techniques; Klebsiella pneumoniae; Male; Moraxella catarrhalis; Ofloxacin; Penicillin Resistance; Piperazines; Respiratory Tract Infections; Streptococcus pneumoniae

2001

Other Studies

9 other study(ies) available for grepafloxacin and clarithromycin

ArticleYear
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2003
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
The in-vitro activity of grepafloxacin against Chlamydia spp., Mycoplasma spp., Ureaplasma urealyticum and Legionella spp.
    The Journal of antimicrobial chemotherapy, 1997, Volume: 40 Suppl A

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Chlamydia; Clarithromycin; Dose-Response Relationship, Drug; Doxycycline; Fluoroquinolones; Gram-Negative Bacteria; Legionella; Mycoplasma; Ofloxacin; Piperazines; Quinolones; Ureaplasma urealyticum

1997
Effect of subinhibitory concentrations of antimicrobial agents (quinolones and macrolide) on the production of verotoxin by enterohemorrhagic Escherichia coli O157:H7.
    Canadian journal of microbiology, 1999, Volume: 45, Issue:9

    Topics: Animals; Anti-Infective Agents; Azithromycin; Bacterial Toxins; Chlorocebus aethiops; Clarithromycin; Dose-Response Relationship, Drug; Enterotoxins; Erythromycin; Escherichia coli O157; Fluoroquinolones; Humans; Macrolides; Norfloxacin; Piperazines; Quinolones; Shiga Toxin 1; Time Factors; Vero Cells

1999
Bactericidal activity of moxifloxacin compared to grepafloxacin and clarithromycin against Streptococcus pneumoniae and Streptococcus pyogenes investigated using an in vitro pharmacodynamic model.
    Journal of chemotherapy (Florence, Italy), 2000, Volume: 12, Issue:6

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Clarithromycin; Erythromycin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Models, Biological; Moxifloxacin; Penicillin Resistance; Piperazines; Quinolines; Streptococcus pneumoniae; Streptococcus pyogenes; Time Factors

2000
The activity of grepafloxacin in two murine models of Mycobacterium avium infection.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2004, Volume: 10, Issue:3

    Topics: Administration, Intranasal; Animals; Clarithromycin; Disease Models, Animal; Ethambutol; Female; Fluoroquinolones; Injections, Intravenous; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Mycobacterium avium Complex; Piperazines; Random Allocation; Rifabutin

2004