granisetron has been researched along with quinuclidines in 50 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (2.00) | 18.2507 |
| 2000's | 11 (22.00) | 29.6817 |
| 2010's | 38 (76.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Clark, R; Eglen, RM; Hegde, SS; Johnson, LG; Lee, CH; Smith, WL; Whiting, RL | 1 |
| Furness, JB; Kumano, K; Kunze, WA; Larsson, H; Murr, E; Vogalis, F | 1 |
| Olver, IN | 1 |
| Board, R; Board, T | 1 |
| Awab, A; Chaudhary, L; Hamadani, M; Tfayli, A | 1 |
| Herrstedt, J | 1 |
| Wilkes, G | 1 |
| Bornstein, JC; Larsson, MH; Lindström, E; Sapnara, M; Sjövall, H; Svensson, DJ; Thomas, EA | 1 |
| Alt, J; Cantoreggi, S; Massuda, EB; Rojas, C; Rubenstein, E; Sebastiani, S; Slusher, B; Snyder, SH; Stathis, M; Thomas, AG; Zhang, J | 1 |
| Huang, Y; Liang, H; Liu, D; Liu, W; Si, X; Wang, L; Yu, Z; Zhang, H | 1 |
| Aogi, K; Inoue, K; Kitagawa, C; Mitsuhashi, S; Ogura, T; Saito, M; Sakai, H; Sekine, I; Yanagita, Y; Yoshizawa, H | 1 |
| Alt, J; Cantoreggi, S; Rojas, C; Rubenstein, EB; Sebastiani, S; Slusher, BS; Stathis, M; Thomas, AG; Zhang, J | 1 |
| Chen, Q; Huang, C; Huang, J; Lin, T; Pan, L; Shen, H; Tian, W; Wang, J; Wang, Z; Zhang, L; Zhang, S; Zhou, J | 1 |
| Billio, A; Clarke, MJ; Morello, E | 2 |
| Basu, A; Hembrom, BP; Naaz, A; Roy, A; Saha, D | 1 |
| Abernethy, AP; Rangwala, F; Zafar, SY | 1 |
| Dakhil, SR; Heckler, CE; Kuebler, JP; Mohile, SG; Morrow, GR; Roscoe, JA; Wade, JL | 1 |
| Connolly, CN; Hothersall, JD; Moffat, C | 1 |
| Hatake, K; Ito, Y; Nakayama, Y; Takahashi, S; Tanabe, M | 1 |
| Lummis, SC; Thompson, AJ | 1 |
| Goto, H; Myojo, T; Osawa, H | 1 |
| Ballinari, G; Barbour, SY; Cox, D; Morrow, GR; Schwartzberg, L; Thorn, MD | 1 |
| Hashimoto, H; Murakami, M; Senba, S; Siraishi, T; Yamaguchi, I; Yamaguchi, K | 1 |
| Iwase, O; Nakajima, A; Nakamura, H; Okuyama, K; Takayanagi, R; Yamada, Y; Yokoyama, H; Yoshimoto, K | 1 |
| Akashi, K; Arita, S; Ariyama, H; Baba, E; Komoda, M; Kumagai, H; Kusaba, H; Nagata, K; Nakano, M; Okumura, Y; Takaishi, S; Tamura, S; Uchida, M | 1 |
| Boccia, R; Cooper, W; Gabrail, N; Gralla, RJ; O'Boyle, E; Raftopoulos, H | 1 |
| Brygger, L; Herrstedt, J | 1 |
| Aoki, Y; Hayashi, K; Higuchi, T; Igarashi, K; Inatani, H; Kato, T; Kimura, H; Nishida, H; Shimozaki, S; Shirai, T; Takeuchi, A; Tanzawa, Y; Tsuchiya, H; Yamamoto, N | 1 |
| Doi, A; Hirayama, M; Kitayama, H; Kondo, T; Sugiyama, J; Tsuji, Y | 1 |
| Horita, H; Hotta, H; Kato, R; Kitamura, H; Kunishima, Y; Masumori, N; Takahashi, A; Takei, F | 1 |
| Fujiwara, S; Kanemura, M; Ohmichi, M; Sasaki, H; Terai, Y; Tsunetoh, S | 1 |
| Baek, JH; Choi, YJ; Chung, JS; Joo, YD; Kim, HJ; Kim, YS; Koh, SJ; Lee, EM; Lee, HG; Lee, WS; Oh, SY; Seol, YM; Yun, EY | 1 |
| Boccia, R; Cooper, W; Gralla, RJ; O'Boyle, E; Raftopoulos, H | 1 |
| Chang, YG; Lee, KB; Lee, WS; Lim, S | 1 |
| Fujimura, T; Fushida, S; Kadoya, N; Kaji, M; Kinami, S; Kinoshita, J; Nezuka, H; Ohta, T; Ohyama, S; Oyama, K; Takai, Y; Takeda, T; Tsuji, K; Tsukada, T; Tsukioka, Y; Yabushita, K | 1 |
| Hou, F; Le, Q; Li, H; Li, W; Liu, S; Shi, Q; Zheng, L; Zong, S | 1 |
| Hashizume, J; Higuchi, N; Kitahara, T; Kodama, Y; Matsunaga, N; Nakamura, T; Sakamoto, T; Sasaki, H; Sato, K; Yamaguchi, K | 1 |
| Aogi, K; Inoue, K; Kitagawa, C; Kubota, K; Ogura, T; Saito, M; Sakai, H; Sekine, I; Yanagita, Y; Yoshizawa, H | 1 |
| Ayuhara, H; Daimon, T; Hama, T; Hayashi, T; Hirai, K; Inoue, K; Itoh, K; Kogure, Y; Nakao, M; Nishio, M; Shibata, K; Suzuki, K; Takeda, K; Tsuji, D; Yokoi, M | 1 |
| Azuma, M; Higuchi, K; Ishido, K; Katada, C; Koizumi, W; Sasaki, T; Tanabe, S; Wada, T; Yano, T | 1 |
| Du, Q; Xu, XL; Yu, B; Zhai, Q; Zhu, B | 1 |
| Arata, K; Azuma, K; Fujiwara, K; Goto, K; Hashimoto, H; Hayashi, T; Kogure, Y; Matsui, R; Nagase, S; Nakao, M; Nogami, N; Ohyanagi, F; Seki, N; Shimada, T; Shimada, Y; Suzuki, K; Takeda, K; Takiguchi, T; Yamamoto, N; Yamanaka, T | 1 |
| Arora, MK; Borle, A; Gouda, D; Goudra, B; Makkar, JK; Singh, PM; Sinha, A; Trikha, A | 1 |
| Abushouk, AI; Ahmed, H; Al Nahrawi, S; Attia, A; Awad, K; Elsherbeny, MY; Mustafa, SM | 1 |
| Liu, Z; Ruan, L; Zhou, C; Zhu, Y | 1 |
| Doggrell, SA | 1 |
| Akashi, K; Kadoyama, K; Kamezaki, K; Kato, K; Miyamoto, T; Mori, Y; Nakamura, T; Shiratsuchi, M; Takenaka, K; Uchida, M | 1 |
| Boccia, R; Calcanes, G; Caruana, D; McBride, A; Mosier, M; Vacirca, J | 1 |
12 review(s) available for granisetron and quinuclidines
| Article | Year |
|---|---|
Update on anti-emetics for chemotherapy-induced emesis.
Topics: Administration, Oral; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Australia; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Granisetron; Humans; Indoles; Isoquinolines; Male; Neoplasms; Ondansetron; Palonosetron; Patient Satisfaction; Prognosis; Quality of Life; Quinolizines; Quinuclidines; Treatment Outcome; Tropisetron; Vomiting | 2005 |
The role of 5-HT3 receptor antagonists in preventing postoperative nausea and vomiting.
Topics: Adult; Algorithms; Antiemetics; Child; Dexamethasone; Drug Administration Schedule; Drug Monitoring; Drug Therapy, Combination; Evidence-Based Medicine; Granisetron; Humans; Indoles; Isoquinolines; Nurse's Role; Nursing Assessment; Ondansetron; Operating Room Nursing; Palonosetron; Patient Selection; Postoperative Nausea and Vomiting; Practice Guidelines as Topic; Quinolizines; Quinuclidines; Risk Assessment; Risk Factors; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists | 2006 |
[Medical treatment of chemotherapy-induced nausea and vomiting].
Topics: Antiemetics; Antineoplastic Agents; Aprepitant; Benzodiazepines; Dexamethasone; Drug Interactions; Drug Therapy, Combination; Evidence-Based Medicine; Ghrelin; Glucocorticoids; Granisetron; Humans; Isoquinolines; Morpholines; Nausea; Neurokinin-1 Receptor Antagonists; Olanzapine; Palonosetron; Peptide Hormones; Practice Guidelines as Topic; Quinuclidines; Serotonin Antagonists; Vomiting | 2007 |
Serotonin receptor antagonists for highly emetogenic chemotherapy in adults.
Topics: Adult; Dexamethasone; Granisetron; Humans; Isoquinolines; Nausea; Ondansetron; Palonosetron; Quinuclidines; Randomized Controlled Trials as Topic; Serotonin 5-HT3 Receptor Antagonists; Vomiting | 2010 |
Gastrointestinal symptoms in cancer patients with advanced disease: new methodologies, insights, and a proposed approach.
Topics: Antiemetics; Antineoplastic Agents; Dexamethasone; Gastrointestinal Diseases; Granisetron; Humans; Isoquinolines; Nausea; Neoplasms; Palliative Care; Palonosetron; Quinuclidines; Serotonin Antagonists; Treatment Outcome; Vomiting; Zingiber officinale | 2012 |
WITHDRAWN: Serotonin receptor antagonists for highly emetogenic chemotherapy in adults.
Topics: Adult; Dexamethasone; Granisetron; Humans; Isoquinolines; Nausea; Ondansetron; Palonosetron; Quinuclidines; Randomized Controlled Trials as Topic; Serotonin 5-HT3 Receptor Antagonists; Vomiting | 2013 |
5-Hydroxytryptamine3 receptor antagonists and cardiac side effects.
Topics: Aged; Antiemetics; Antineoplastic Agents; Cardiovascular Diseases; Granisetron; Humans; Isoquinolines; Long QT Syndrome; Nausea; Neoplasms; Ondansetron; Palonosetron; Quinuclidines; Serotonin 5-HT3 Receptor Antagonists; Vomiting | 2014 |
Prevention of cisplatin-based chemotherapy-induced delayed nausea and vomiting using triple antiemetic regimens: a mixed treatment comparison.
Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Cisplatin; Dexamethasone; Drug Therapy, Combination; Granisetron; Humans; Isoquinolines; Morpholines; Nausea; Neoplasms; Network Meta-Analysis; Ondansetron; Palonosetron; Quinuclidines; Randomized Controlled Trials as Topic; Spiro Compounds; Treatment Outcome; Vomiting | 2016 |
Efficacy of palonosetron in postoperative nausea and vomiting (PONV)-a meta-analysis.
Topics: Adult; Anesthesia, General; Antiemetics; Benzimidazoles; Granisetron; Humans; Isoquinolines; Ondansetron; Palonosetron; Postoperative Nausea and Vomiting; Quinuclidines; Randomized Controlled Trials as Topic; Serotonin Antagonists; Treatment Outcome | 2016 |
Dexamethasone combined with other antiemetics versus single antiemetics for prevention of postoperative nausea and vomiting after laparoscopic cholecystectomy: An updated systematic review and meta-analysis.
Topics: Antiemetics; Benzimidazoles; Cholecystectomy, Laparoscopic; Dexamethasone; Drug Therapy, Combination; Granisetron; Humans; Isoquinolines; Metoclopramide; Ondansetron; Palonosetron; Postoperative Nausea and Vomiting; Quinuclidines; Randomized Controlled Trials as Topic | 2016 |
5-HT3 receptor antagonists for the prevention of postoperative shivering: a meta-analysis.
Topics: Analgesics, Opioid; Granisetron; Humans; Indoles; Isoquinolines; Meperidine; Ondansetron; Palonosetron; Postoperative Complications; Postoperative Period; Quinuclidines; Randomized Controlled Trials as Topic; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Antagonists; Shivering; Surgical Procedures, Operative; Tropisetron | 2016 |
Granisetron in the treatment of chemotherapy-induced nausea and vomiting (CINV) - is there still a role after comparison with palonosetron?
Topics: Administration, Cutaneous; Antiemetics; Antineoplastic Agents; Clinical Trials as Topic; Dexamethasone; Granisetron; Humans; Isoquinolines; Nausea; Palonosetron; Quinuclidines; Vomiting | 2017 |
18 trial(s) available for granisetron and quinuclidines
| Article | Year |
|---|---|
The efficacy and safety of palonosetron compared with granisetron in preventing highly emetogenic chemotherapy-induced vomiting in the Chinese cancer patients: a phase II, multicenter, randomized, double-blind, parallel, comparative clinical trial.
Topics: Adult; Antiemetics; Antineoplastic Agents; Asian People; China; Double-Blind Method; Female; Granisetron; Humans; Isoquinolines; Male; Middle Aged; Neoplasms; Palonosetron; Quinuclidines; Serotonin Antagonists; Vomiting | 2009 |
Palonosetron plus dexamethasone versus granisetron plus dexamethasone for prevention of nausea and vomiting during chemotherapy: a double-blind, double-dummy, randomised, comparative phase III trial.
Topics: Adult; Antiemetics; Antineoplastic Agents; Dexamethasone; Double-Blind Method; Female; Granisetron; Humans; Isoquinolines; Male; Middle Aged; Nausea; Neoplasms; Palonosetron; Quinuclidines; Serotonin Antagonists; Vomiting | 2009 |
Randomized, double-blind, crossover study of palonosetron compared with granisetron for the prevention of chemotherapy-induced nausea and vomiting in a Chinese population.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Asian People; China; Cross-Over Studies; Double-Blind Method; Female; Granisetron; Humans; Isoquinolines; Male; Middle Aged; Nausea; Neoplasms; Palonosetron; Quinuclidines; Serotonin Antagonists; Survival Rate; Treatment Outcome; Vomiting; Young Adult | 2011 |
Comparison of palanosetron, granisetron and ondansetron as anti-emetics for prevention of postoperative nausea and vomiting in patients undergoing middle ear surgery.
Topics: Adult; Antiemetics; Ear, Middle; Female; Granisetron; Humans; Isoquinolines; Male; Middle Aged; Ondansetron; Palonosetron; Postoperative Nausea and Vomiting; Quinuclidines; Serotonin 5-HT3 Receptor Antagonists | 2011 |
Prevention of delayed nausea: a University of Rochester Cancer Center Community Clinical Oncology Program study of patients receiving chemotherapy.
Topics: Antiemetics; Antineoplastic Agents; Aprepitant; Dexamethasone; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Granisetron; Humans; Intention to Treat Analysis; Isoquinolines; Male; Middle Aged; Morpholines; Nausea; Neurokinin-1 Receptor Antagonists; Palonosetron; Prochlorperazine; Quinuclidines; Serotonin Antagonists | 2012 |
A combination of aprepitant, palonosetron, and dexamethasone prevents emesis associated with anthracycline-containing regimens for patients with breast cancer. A retrospective study.
Topics: Adult; Aged; Anthracyclines; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Breast Neoplasms; Dexamethasone; Female; Granisetron; Humans; Isoquinolines; Middle Aged; Morpholines; Palonosetron; Quinuclidines; Retrospective Studies; Treatment Outcome; Vomiting | 2015 |
Pooled analysis of phase III clinical studies of palonosetron versus ondansetron, dolasetron, and granisetron in the prevention of chemotherapy-induced nausea and vomiting (CINV).
Topics: Antiemetics; Antineoplastic Agents; Double-Blind Method; Female; Granisetron; Humans; Indoles; Isoquinolines; Male; Middle Aged; Nausea; Neoplasms; Ondansetron; Palonosetron; Quinolizines; Quinuclidines; Serotonin Antagonists; Treatment Outcome; Vomiting | 2014 |
Effectiveness of palonosetron for preventing delayed chemotherapy-induced nausea and vomiting following moderately emetogenic chemotherapy in patients with gastrointestinal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Agents; Female; Gastrointestinal Neoplasms; Granisetron; Humans; Isoquinolines; Male; Middle Aged; Nausea; Palonosetron; Prospective Studies; Quinuclidines; Surveys and Questionnaires; Vomiting | 2014 |
Comparison of an extended-release formulation of granisetron (APF530) versus palonosetron for the prevention of chemotherapy-induced nausea and vomiting associated with moderately or highly emetogenic chemotherapy: results of a prospective, randomized, do
Topics: Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Delayed-Action Preparations; Double-Blind Method; Female; Granisetron; Humans; Isoquinolines; Male; Middle Aged; Nausea; Neoplasms; Palonosetron; Prospective Studies; Quinuclidines; Severity of Illness Index; Treatment Outcome; Vomiting | 2015 |
Efficacy of triplet regimen antiemetic therapy for chemotherapy-induced nausea and vomiting (CINV) in bone and soft tissue sarcoma patients receiving highly emetogenic chemotherapy, and an efficacy comparison of single-shot palonosetron and consecutive-da
Topics: Adolescent; Adult; Aged; Antiemetics; Antineoplastic Agents; Aprepitant; Bone Neoplasms; Cross-Over Studies; Dexamethasone; Drug Administration Schedule; Drug Therapy, Combination; Female; Granisetron; Humans; Isoquinolines; Male; Middle Aged; Morpholines; Nausea; Neurokinin-1 Receptor Antagonists; Palonosetron; Quinuclidines; Sarcoma; Serotonin 5-HT3 Receptor Antagonists; Treatment Outcome; Vomiting; Young Adult | 2015 |
Efficacy of palonosetron and 1-day dexamethasone in moderately emetogenic chemotherapy compared with fosaprepitant, granisetron, and dexamethasone: a prospective randomized crossover study.
Topics: Aged; Antiemetics; Antineoplastic Agents; Cross-Over Studies; Dexamethasone; Drug Therapy, Combination; Female; Granisetron; Humans; Isoquinolines; Male; Middle Aged; Morpholines; Nausea; Palonosetron; Patient Preference; Prospective Studies; Quinuclidines; Single-Blind Method; Treatment Outcome; Vomiting | 2015 |
Palonosetron versus granisetron in combination with aprepitant for the prevention of chemotherapy-induced nausea and vomiting in patients with gynecologic cancer.
Topics: Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Carboplatin; Cross-Over Studies; Diet; Drug Administration Schedule; Female; Genital Neoplasms, Female; Granisetron; Humans; Isoquinolines; Middle Aged; Morpholines; Nausea; Paclitaxel; Palonosetron; Quinuclidines; Serotonin 5-HT3 Receptor Antagonists; Vomiting | 2015 |
Transdermal granisetron versus palonosetron for prevention of chemotherapy-induced nausea and vomiting following moderately emetogenic chemotherapy: a multicenter, randomized, open-label, cross-over, active-controlled, and phase IV study.
Topics: Administration, Cutaneous; Adult; Aged; Antiemetics; Antineoplastic Agents; Cross-Over Studies; Double-Blind Method; Female; Granisetron; Humans; Isoquinolines; Male; Middle Aged; Nausea; Palonosetron; Patient Satisfaction; Quinuclidines; Remission Induction; Serotonin Antagonists; Vomiting | 2016 |
Slow-release granisetron (APF530) versus palonosetron for chemotherapy-induced nausea/vomiting: analysis by American Society of Clinical Oncology emetogenicity criteria.
Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Delayed-Action Preparations; Female; Granisetron; Humans; Isoquinolines; Male; Middle Aged; Nausea; Neoplasms; Palonosetron; Quinuclidines; Serotonin Antagonists; Treatment Outcome; Vomiting | 2015 |
Comparison of palonosetron, granisetron, and ramosetron for the prevention of postoperative nausea and vomiting after laparoscopic gynecologic surgery: a prospective randomized trial.
Topics: Adult; Aged; Benzimidazoles; Double-Blind Method; Female; Granisetron; Gynecologic Surgical Procedures; Humans; Isoquinolines; Laparoscopy; Middle Aged; Palonosetron; Postoperative Nausea and Vomiting; Prospective Studies; Quinuclidines; Serotonin 5-HT3 Receptor Antagonists | 2015 |
Control of nausea with palonosetron versus granisetron, both combined with dexamethasone, in patients receiving cisplatin- or anthracycline plus cyclophosphamide-based regimens.
Topics: Anthracyclines; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Dexamethasone; Female; Granisetron; Humans; Isoquinolines; Male; Middle Aged; Nausea; Palonosetron; Quinuclidines; Vomiting | 2016 |
Aprepitant, granisetron, and dexamethasone versus palonosetron and dexamethasone for prophylaxis of cisplatin-induced nausea and vomiting in patients with upper gastrointestinal cancer: a randomized crossover phase II trial (KDOG 1002).
Topics: Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Cisplatin; Cross-Over Studies; Dexamethasone; Esophageal Neoplasms; Female; Granisetron; Humans; Isoquinolines; Male; Middle Aged; Morpholines; Nausea; Palonosetron; Quinuclidines; Serotonin Antagonists; Stomach Neoplasms; Vomiting | 2016 |
Randomized, double-blind, phase III trial of palonosetron versus granisetron in the triplet regimen for preventing chemotherapy-induced nausea and vomiting after highly emetogenic chemotherapy: TRIPLE study.
Topics: Adult; Aged; Antineoplastic Agents; Cisplatin; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Female; Granisetron; Humans; Isoquinolines; Male; Middle Aged; Nausea; Neoplasms; Palonosetron; Quinuclidines; Serotonin Antagonists; Vomiting | 2016 |
20 other study(ies) available for granisetron and quinuclidines
| Article | Year |
|---|---|
Pharmacological characterization of RS 25259-197, a novel and selective 5-HT3 receptor antagonist, in vivo.
Topics: Administration, Oral; Animals; Bradycardia; Dogs; Dose-Response Relationship, Drug; Duodenum; Female; Ferrets; Granisetron; Hemodynamics; Injections, Intravenous; Injections, Subcutaneous; Isoquinolines; Male; Ondansetron; Palonosetron; Quinuclidines; Random Allocation; Rats; Serotonin; Serotonin Antagonists; Stereoisomerism; Vomiting | 1995 |
Sensitization of enteric reflexes in the rat colon in vitro.
Topics: Animals; Area Under Curve; Carbachol; Cholinergic Agonists; Colon; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; Gastrointestinal Motility; Granisetron; Hexamethonium; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Neurons, Afferent; Nicotinic Antagonists; Piperidines; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Receptors, Tachykinin; Serotonin Antagonists; Time Factors | 2002 |
5HT3-receptor antagonists as antiemetics in cancer.
Topics: Adult; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Child; Granisetron; Humans; Indoles; Isoquinolines; Nausea; Neoplasms; Ondansetron; Palonosetron; Practice Guidelines as Topic; Quinolizines; Quinuclidines; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Tropisetron; Vomiting | 2005 |
Relative efficacy of ondansetron, granisetron, dolasetron and palonosetron in controlling acute nausea and vomiting associated with platinum-based chemotherapy.
Topics: Antiemetics; Granisetron; Humans; Indoles; Isoquinolines; Nausea; Ondansetron; Organoplatinum Compounds; Palonosetron; Quinolizines; Quinuclidines; Treatment Outcome; Vomiting | 2006 |
Antiemetic agents.
Topics: Administration, Oral; Anorexia; Antiemetics; Antineoplastic Agents; Aprepitant; Asthenia; Constipation; Diarrhea; Drug Interactions; Dyspepsia; Fatigue; Fever; Granisetron; Headache; Hiccup; Humans; Indoles; Injections, Intravenous; Isoquinolines; Morpholines; Nausea; Neoplasms; Ondansetron; Palonosetron; Quinolizines; Quinuclidines; Vomiting | 2007 |
Pharmacological analysis of components of the change in transmural potential difference evoked by distension of rat proximal small intestine in vivo.
Topics: Anesthetics, Local; Animals; Atropine; Chlorides; Colon; Duodenum; Enzyme Inhibitors; Ganglionic Blockers; Granisetron; Hexamethonium; Hormone Antagonists; Injections, Intravenous; Intestinal Secretions; Lidocaine; Male; Mechanotransduction, Cellular; Membrane Potentials; Mice; Mice, Inbred C57BL; Muscarinic Antagonists; Neurokinin-1 Receptor Antagonists; Nitric Oxide Synthase; Nitroarginine; Peripheral Nervous System Agents; Piperidines; Pressure; Quinolines; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Receptors, Serotonin, 5-HT3; Receptors, Vasoactive Intestinal Peptide; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Tetrodotoxin; Time Factors; Vasoactive Intestinal Peptide | 2008 |
Palonosetron exhibits unique molecular interactions with the 5-HT3 receptor.
Topics: Animals; Antiemetics; Binding Sites; Calcium; Cell Line; Granisetron; Isoquinolines; Ondansetron; Palonosetron; Postoperative Nausea and Vomiting; Quinuclidines; Radioligand Assay; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Antagonists; Transfection | 2008 |
Palonosetron triggers 5-HT(3) receptor internalization and causes prolonged inhibition of receptor function.
Topics: Animals; Cell Line; Cell Membrane; Cell-Free System; Granisetron; Humans; Isoquinolines; Isotope Labeling; Microscopy, Fluorescence; Palonosetron; Protein Transport; Quinuclidines; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Antagonists; Substrate Specificity; Time Factors; Tritium | 2010 |
Prolonged inhibition of 5-HT₃ receptors by palonosetron results from surface receptor inhibition rather than inducing receptor internalization.
Topics: Allosteric Regulation; Animals; Antiemetics; Cell Membrane; Chlorocebus aethiops; COS Cells; Down-Regulation; Endocytosis; Granisetron; Humans; Hydrazones; Isoquinolines; Kinetics; Nystatin; Palonosetron; Protein Transport; Quinuclidines; Radioligand Assay; Receptors, Serotonin, 5-HT3; Recombinant Proteins; Serotonin 5-HT3 Receptor Antagonists | 2013 |
Agonists and antagonists induce different palonosetron dissociation rates in 5-HT₃A and 5-HT₃AB receptors.
Topics: Granisetron; HEK293 Cells; Humans; Inhibitory Concentration 50; Isoquinolines; Palonosetron; Protein Subunits; Quinuclidines; Radioligand Assay; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists; Transfection; Tritium | 2013 |
[Comparison of antiemesis effects of granisetron, aprepitant and dexamethasone to palonosetron, aprepitant and dexamethasone in treatment of high-emetic risk chemotherapy-induced nausea and vomiting - a retrospective study for efficacy and safety in a sin
Topics: Aged; Antiemetics; Antineoplastic Agents; Aprepitant; Dexamethasone; Drug Combinations; Female; Granisetron; Humans; Isoquinolines; Male; Middle Aged; Morpholines; Nausea; Neoplasms; Palonosetron; Quinuclidines; Retrospective Studies; Risk; Vomiting | 2013 |
Theoretical evaluation of antiemetic effects of 5-HT3 receptor antagonists for prevention of vomiting induced by cisplatin.
Topics: Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Cisplatin; Constipation; Creatinine; Granisetron; Humans; Hydroxyindoleacetic Acid; Intestine, Small; Isoquinolines; Models, Biological; Nausea; Oxazines; Palonosetron; Quinuclidines; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin 5-HT3 Receptor Antagonists; Vomiting | 2015 |
Efficacy and safety of an increased-dose of dexamethasone in patients receiving fosaprepitant chemotherapy in Japan.
Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Aprepitant; Benzimidazoles; Dexamethasone; Drug Therapy, Combination; Female; Granisetron; Humans; Isoquinolines; Japan; Male; Middle Aged; Morpholines; Neoplasms; Palonosetron; Quinuclidines; Retrospective Studies; Serotonin Antagonists; Vomiting | 2014 |
Palonosetron with aprepitant plus dexamethasone to prevent chemotherapy-induced nausea and vomiting during gemcitabine/cisplatin in urothelial cancer patients.
Topics: Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Carcinoma, Transitional Cell; Cisplatin; Deoxycytidine; Dexamethasone; Drug Therapy, Combination; Female; Gemcitabine; Granisetron; Humans; Isoquinolines; Kidney Neoplasms; Male; Middle Aged; Morpholines; Nausea; Ondansetron; Palonosetron; Quinuclidines; Retrospective Studies; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Ureteral Neoplasms; Urinary Bladder Neoplasms; Urologic Neoplasms; Vomiting | 2015 |
Evaluation of the efficacy of palonosetron for prevention of chemotherapy-induced nausea and vomiting in patients with gastric cancer treated with S-1 plus cisplatin.
Topics: Aged; Aged, 80 and over; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Cisplatin; Dexamethasone; Drug Combinations; Drug Therapy, Combination; Female; Granisetron; Humans; Isoquinolines; Male; Middle Aged; Morpholines; Nausea; Oxonic Acid; Palonosetron; Prospective Studies; Quality of Life; Quinuclidines; Stomach Neoplasms; Surveys and Questionnaires; Tegafur; Vomiting | 2016 |
Evaluation of Antiemetic Therapy for Hepatic Transcatheter Arterial Infusion Chemotherapy with Cisplatin.
Topics: Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Agents; Aprepitant; Bridged Bicyclo Compounds, Heterocyclic; Catheterization, Peripheral; Cisplatin; Dexamethasone; Drug Therapy, Combination; Female; Granisetron; Humans; Isoquinolines; Liver; Liver Neoplasms; Male; Middle Aged; Morpholines; Nausea; Oxazines; Palonosetron; Quinuclidines; Serotonin 5-HT3 Receptor Antagonists; Vomiting | 2016 |
Influence of ABCB1 and ABCG2 polymorphisms on the antiemetic efficacy in patients with cancer receiving cisplatin-based chemotherapy: a TRIPLE pharmacogenomics study.
Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; Cisplatin; Female; Genotype; Granisetron; Humans; Isoquinolines; Logistic Models; Male; Middle Aged; Multivariate Analysis; Neoplasm Proteins; Palonosetron; Pharmacogenomic Testing; Polymorphism, Single Nucleotide; Quinuclidines | 2017 |
Economic evaluation of 5-HT3 receptor antagonists in combination with dexamethasone for the prevention of 'overall' nausea and vomiting following highly emetogenic chemotherapy in Chinese adult patients.
Topics: Adult; Antiemetics; Antineoplastic Agents; Asian People; Clinical Trials, Phase III as Topic; Cost-Benefit Analysis; Dexamethasone; Granisetron; Humans; Isoquinolines; Nausea; Ondansetron; Palonosetron; Quinuclidines; Randomized Controlled Trials as Topic; Receptors, Serotonin, 5-HT3; Vomiting | 2017 |
Comparison between Antiemetic Effects of Palonosetron and Granisetron on Chemotherapy-Induced Nausea and Vomiting in Japanese Patients Treated with R-CHOP.
Topics: Adult; Aged; Aging; Antibodies, Monoclonal, Murine-Derived; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Asian People; Cyclophosphamide; Doxorubicin; Female; Granisetron; Humans; Isoquinolines; Lymphoma, Non-Hodgkin; Male; Middle Aged; Nausea; Palonosetron; Prednisone; Quinuclidines; Risk Factors; Rituximab; Sex Characteristics; Treatment Outcome; Vincristine; Vomiting; Young Adult | 2017 |
Hydration requirements with emetogenic chemotherapy: granisetron extended-release subcutaneous versus palonosetron.
Topics: Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Delayed-Action Preparations; Dexamethasone; Female; Fluid Therapy; Granisetron; Humans; Injections, Subcutaneous; Isoquinolines; Male; Middle Aged; Nausea; Neoplasms; Palonosetron; Practice Guidelines as Topic; Quinuclidines; Retrospective Studies; Serotonin Antagonists; Treatment Outcome; Vomiting | 2018 |