Compounds > gr 73632
Page last updated: 2024-09-03

gr 73632 and substance p, sar(9)-met(o2)(11)-

gr 73632 has been researched along with substance p, sar(9)-met(o2)(11)- in 5 studies

Compound Research Comparison

Studies
(gr 73632)		Trials
(gr 73632)		Recent Studies (post-2010)
(gr 73632)		Studies
(substance p, sar(9)-met(o2)(11)-)		Trials
(substance p, sar(9)-met(o2)(11)-)		Recent Studies (post-2010) (substance p, sar(9)-met(o2)(11)-)
771915106

Protein Interaction Comparison

ProteinTaxonomygr 73632 (IC50)substance p, sar(9)-met(o2)(11)- (IC50)
Substance-P receptorHomo sapiens (human)0.0006

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bristow, LJ; Young, L1
Dalforno, G; Gaviraghi, G; Hagan, RM; Palea, S; Pietra, C; Trist, DG1
Huizinga, JD; Nieuwmeyer, F; Ye, J1
Asai, H; Ishii, T; Kiuchi, S; Nagasaki, M; Okamoto, M; Saito, A; Taniguchi, H; Watanabe, Y1
Bongianni, F; Cinelli, E; Mutolo, D; Pantaleo, T1

Other Studies

5 other study(ies) available for gr 73632 and substance p, sar(9)-met(o2)(11)-

ArticleYear
Chromodacryorrhea and repetitive hind paw tapping: models of peripheral and central tachykinin NK1 receptor activation in gerbils.
    European journal of pharmacology, 1994, Mar-03, Volume: 253, Issue:3

    Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Synergism; Gerbillinae; Harderian Gland; Indoles; Injections, Intravenous; Injections, Intraventricular; Isoindoles; Male; Neurokinin A; Peptide Fragments; Piperidines; Receptors, Neurokinin-1; Substance P

1994
Further studies on the effects of selective neurokinin agonists upon the activation of micturition reflex in rats. Evidence for a dual NK-1 receptor mediated excitatory and inhibitory activity.
    Neuropeptides, 1993, Volume: 24, Issue:5

    Topics: Animals; Dose-Response Relationship, Drug; Injections, Intra-Arterial; Injections, Intraventricular; Male; Neurokinin A; Peptide Fragments; Physalaemin; Rats; Rats, Wistar; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Reflex; Substance P; Urinary Bladder; Urination

1993
Ava[L-Pro9,N-MeLeu10] substance P(7-11) (GR 73632) and Sar9, Met(O2)11 increase distention-induced peristalsis through activation of neurokinin-1 receptors on smooth muscle and interstitial cells of cajal.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 317, Issue:1

    Topics: Action Potentials; Animals; Coiled Bodies; Dilatation; Female; Guinea Pigs; In Vitro Techniques; Intestine, Small; Mice; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Peristalsis; Piperidines; Quinuclidines; Receptors, Neurokinin-1; Substance P

2006
Pharmacological characterization of T-2328, 2-fluoro-4'-methoxy-3'-[[[(2S,3S)-2-phenyl-3-piperidinyl]amino]methyl]-[1,1'-biphenyl]-4-carbonitrile dihydrochloride, as a brain-penetrating antagonist of tachykinin NK1 receptor.
    Journal of pharmacological sciences, 2008, Volume: 106, Issue:1

    Topics: Animals; Antiemetics; Antineoplastic Agents; Aprepitant; Binding Sites; Brain; Cell Line, Tumor; CHO Cells; Cisplatin; Cricetinae; Cricetulus; Disease Models, Animal; Dose-Response Relationship, Drug; Ferrets; Gerbillinae; Humans; Kinetics; Male; Morpholines; Motor Activity; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Receptors, Neurokinin-1; Substance P; Transfection; Vomiting

2008
Neurokinin receptor modulation of respiratory activity in the rabbit.
    The European journal of neuroscience, 2008, Volume: 27, Issue:12

    Topics: Animals; Exhalation; Inhalation; Male; Medulla Oblongata; Microinjections; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Phrenic Nerve; Piperidines; Rabbits; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Substance P; Vagotomy

2008