Page last updated: 2024-09-03

gr 65630 and tropisetron

gr 65630 has been researched along with tropisetron in 3 studies

Compound Research Comparison

Studies
(gr 65630)
Trials
(gr 65630)
Recent Studies (post-2010)
(gr 65630)
Studies
(tropisetron)
Trials
(tropisetron)
Recent Studies (post-2010) (tropisetron)
5704944218150

Protein Interaction Comparison

ProteinTaxonomygr 65630 (IC50)tropisetron (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)3.1623
Muscarinic acetylcholine receptor M2Homo sapiens (human)3.1623
Muscarinic acetylcholine receptor M5Homo sapiens (human)3.45
Neuronal acetylcholine receptor subunit beta-4Homo sapiens (human)1.8
Sodium-dependent serotonin transporterHomo sapiens (human)0.488
Neuronal acetylcholine receptor subunit alpha-3Homo sapiens (human)1.8

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Higgins, GA; Jones, BJ; Oakley, NR; Tyers, MB1
Abdel-Aziz, H; Ploch, M; Verspohl, EJ; Windeck, T1
Hauk, F; Heimes, K; Verspohl, EJ1

Other Studies

3 other study(ies) available for gr 65630 and tropisetron

ArticleYear
Evidence that the amygdala is involved in the disinhibitory effects of 5-HT3 receptor antagonists.
    Psychopharmacology, 1991, Volume: 104, Issue:4

    Topics: Amygdala; Animals; Anxiety; Conflict, Psychological; Granisetron; Imidazoles; Indazoles; Indoles; Lighting; Male; Ondansetron; Raphe Nuclei; Rats; Serotonin; Serotonin Antagonists; Social Behavior; Tropanes; Tropisetron

1991
Mode of action of gingerols and shogaols on 5-HT3 receptors: binding studies, cation uptake by the receptor channel and contraction of isolated guinea-pig ileum.
    European journal of pharmacology, 2006, Jan-13, Volume: 530, Issue:1-2

    Topics: Animals; Binding, Competitive; Carbon Radioisotopes; Catechols; Cations; Cell Line, Tumor; Dose-Response Relationship, Drug; Fatty Alcohols; Guanidine; Guinea Pigs; Humans; Ileum; Imidazoles; In Vitro Techniques; Indoles; Ion Channels; Isotonic Contraction; Male; Mice; Organic Cation Transport Proteins; Piperidines; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Sodium Channels; Substance P; Tritium; Tropisetron; Veratridine; Zingiber officinale

2006
Mode of action of peppermint oil and (-)-menthol with respect to 5-HT3 receptor subtypes: binding studies, cation uptake by receptor channels and contraction of isolated rat ileum.
    Phytotherapy research : PTR, 2011, Volume: 25, Issue:5

    Topics: Animals; Antiemetics; Binding, Competitive; Cell Line, Tumor; Dose-Response Relationship, Drug; Female; Guanidine; Humans; Ileum; Imidazoles; Indoles; Ion Channels; Isotonic Contraction; Male; Mentha piperita; Menthol; Mice; Plant Oils; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin 5-HT3 Receptor Antagonists; Tropisetron

2011