Page last updated: 2024-09-05

gr 144053 and eptifibatide

gr 144053 has been researched along with eptifibatide in 3 studies

Compound Research Comparison

Studies (gr 144053)	Trials (gr 144053)	Recent Studies (post-2010) (gr 144053)	Studies (eptifibatide)	Trials (eptifibatide)	Recent Studies (post-2010) (eptifibatide)
21	1	2	907	220	212

Protein Interaction Comparison

Protein	Taxonomy	gr 144053 (IC50)	eptifibatide (IC50)
Integrin beta-3	Homo sapiens (human)		0.226
Integrin alpha-IIb	Homo sapiens (human)		0.226

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (33.33)	18.2507
2000's	2 (66.67)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Gretler, DD; Scarborough, RM	1
Heptinstall, S; Storey, RF; Wilcox, RG	1
Rozalski, M; Watala, C	1

Reviews

1 review(s) available for gr 144053 and eptifibatide

Article	Year
Platelet glycoprotein IIb-IIIa antagonists as prototypical integrin blockers: novel parenteral and potential oral antithrombotic agents. Journal of medicinal chemistry, 2000, Sep-21, Volume: 43, Issue:19 Topics: Administration, Oral; Animals; Antibodies, Monoclonal; Clinical Trials as Topic; Drug Design; Fibrinolytic Agents; Humans; Injections; Integrins; Molecular Mimicry; Peptides; Platelet Glycoprotein GPIIb-IIIa Complex; Snake Venoms	2000

Article

Year

Platelet glycoprotein IIb-IIIa antagonists as prototypical integrin blockers: novel parenteral and potential oral antithrombotic agents.

Journal of medicinal chemistry, 2000, Sep-21, Volume: 43, Issue:19

Topics: Administration, Oral; Animals; Antibodies, Monoclonal; Clinical Trials as Topic; Drug Design; Fibrinolytic Agents; Humans; Injections; Integrins; Molecular Mimicry; Peptides; Platelet Glycoprotein GPIIb-IIIa Complex; Snake Venoms

2000

Trials

1 trial(s) available for gr 144053 and eptifibatide

Article	Year
Differential effects of glycoprotein IIb/IIIa antagonists on platelet microaggregate and macroaggregate formation and effect of anticoagulant on antagonist potency. Implications for assay methodology and comparison of different antagonists. Circulation, 1998, Oct-20, Volume: 98, Issue:16 Topics: Adenosine Diphosphate; Anticoagulants; Citrates; Collagen; Eptifibatide; Hirudins; Humans; Nephelometry and Turbidimetry; Oligopeptides; Peptides; Peptides, Cyclic; Piperazines; Piperidines; Platelet Aggregation Inhibitors; Platelet Count; Platelet Glycoprotein GPIIb-IIIa Complex; Sodium Citrate; Thiazolidines	1998

Article

Year

Differential effects of glycoprotein IIb/IIIa antagonists on platelet microaggregate and macroaggregate formation and effect of anticoagulant on antagonist potency. Implications for assay methodology and comparison of different antagonists.

Circulation, 1998, Oct-20, Volume: 98, Issue:16

Topics: Adenosine Diphosphate; Anticoagulants; Citrates; Collagen; Eptifibatide; Hirudins; Humans; Nephelometry and Turbidimetry; Oligopeptides; Peptides; Peptides, Cyclic; Piperazines; Piperidines; Platelet Aggregation Inhibitors; Platelet Count; Platelet Glycoprotein GPIIb-IIIa Complex; Sodium Citrate; Thiazolidines

1998

Other Studies

1 other study(ies) available for gr 144053 and eptifibatide

Article	Year
Antagonists of platelet fibrinogen receptor are less effective in carriers of Pl(A2) polymorphism of beta(3) integrin. European journal of pharmacology, 2002, Nov-01, Volume: 454, Issue:1 Topics: Adult; Eptifibatide; Female; Genotype; Humans; Integrin beta3; Intercellular Signaling Peptides and Proteins; Male; Nephelometry and Turbidimetry; Peptides; Piperazines; Piperidines; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Polymorphism, Genetic; Receptors, Fibrinogen	2002

Article

Year

Antagonists of platelet fibrinogen receptor are less effective in carriers of Pl(A2) polymorphism of beta(3) integrin.

European journal of pharmacology, 2002, Nov-01, Volume: 454, Issue:1

Topics: Adult; Eptifibatide; Female; Genotype; Humans; Integrin beta3; Intercellular Signaling Peptides and Proteins; Male; Nephelometry and Turbidimetry; Peptides; Piperazines; Piperidines; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Polymorphism, Genetic; Receptors, Fibrinogen

2002