gr 127935 has been researched along with sumatriptan in 43 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 30 (69.77) | 18.2507 |
| 2000's | 10 (23.26) | 29.6817 |
| 2010's | 2 (4.65) | 24.3611 |
| 2020's | 1 (2.33) | 2.80 |
| Authors | Studies |
|---|---|
| Gommeren, W; Haegeman, G; Heylen, L; Lesage, AS; Leysen, JE; Luyten, WH; Schotte, A; Van de Weyer, I; Van Gompel, P; Vanhoenacker, P; Wouters, R | 1 |
| Grånäs, C; Larhammar, D | 1 |
| Audia, JE; Krushinski, JH; Lucaites, VL; Nelson, DL; Schaus, JM; Wainscott, DB; Zgombick, JM | 1 |
| Hill, RG; Longmore, J; Razzaque, Z | 1 |
| Maura, G; Raiteri, M | 1 |
| Bobirnac, I; Schoeffter, P | 1 |
| Crick, H; Manuel, NA; Wallis, DI | 1 |
| Beattie, DT; Connor, HE; Walsh, DM | 1 |
| De Vries, P; Heiligers, JP; Saxena, PR; Villalón, CM | 2 |
| Terrón, JA | 1 |
| Bonnafous, R; John, GW; Valentin, JP | 1 |
| Centurión, D; Sánchez-López, A; Villalón, CM | 1 |
| Apaydin, S; De Vries, P; Heiligers, JP; Saxena, PR; Villalón, CM | 1 |
| Curtis, MJ; Ellwood, AJ | 2 |
| Hållbus, M; Magnusson, O; Magnusson, T | 1 |
| Cutrer, FM; Moskowitz, MA; Waeber, C; Yu, XJ | 1 |
| Beleta, J; Bernabeu, E; Bou, J; Cortijo, J; Domènech, T; Fernández, AG; Martí-Cabrera, M; Morcillo, EJ; Palacios, JM | 1 |
| John, GW; Le Grand, B; Vié, B | 1 |
| Pauwels, PJ | 1 |
| John, GW; Le Grand, B; Panissié, A; Pauwels, PJ | 1 |
| Gaster, LM; Hagan, JJ; Ham, P; Joiner, GF; King, FD; Middlemiss, DN; Mulholland, KR; Price, GW; Roberts, C; Routledge, C; Selkirk, J; Slade, PD; Wyman, PA | 1 |
| Centurión, D; Rabelo, G; Sánchez-López, A; Villalón, CM | 1 |
| Beer, MS; Heald, MA; Hill, RG; Longmore, J; Maskell, L; Pickard, JD; Razzaque, Z | 1 |
| Centurión, D; De Vries, P; Rabelo, G; Sánchez-López, A; Saxena, P; Villalón, CM | 1 |
| Cohen, ML; Hemrick-Luecke, SH; Schenck, KW | 1 |
| Li, XF; Lovren, F; Lytton, J; Triggle, C | 1 |
| De Vries, P; Heiligers, JP; Saxena, PR; Trion, M; Villalón, CM; Willems, EW | 1 |
| Bischoff, A; Diener, H; Fetscher, C; Limmroth, V; Michel, MC; Wermelskirchen, D | 1 |
| Ferrari, MD; Maassen Van Den Brink, A; Roon, KI; Saxena, PR | 1 |
| Chen, J; Purdy, RE; Yildiz, O | 1 |
| Davidson, C; Hopwood, SE; McLaughlin, DP; Stamford, JA | 1 |
| Cordi, AA; Ragonnet, C; Vayssettes-Courchay, C; Verbeuren, TJ | 1 |
| Centurión, D; Sánchez-López, A; Saxena, PR; Villalón, CM | 1 |
| Akita, H; Inoue, N; Ishida, T; Kawashima, S; Miwa, Y; Sakoda, T; Shimokawa, Y; Shiomi, M; Ueyama, T; Yokoyama, M | 1 |
| Crema, A; Crema, F; De Ponti, F; Frigo, G; Moro, E; Nardelli, G | 1 |
| Arulmani, U; Centurión, D; Sánchez-López, A; Saxena, PR; Vázquez, E; Villalón, CM | 1 |
| Jähnichen, S; Pertz, HH; Radtke, OA | 1 |
| Blanchet, JC; John, GW; Le Grand, B; Létienne, R; Sole, E | 1 |
| Afshari, K; Daneshpazhooh, M; Dehpour, AR; Foroutan, A; Haddadi, NS; Ostadhadi, S; Shakiba, S | 1 |
| Abbaszadeh-Kasbi, A; Afshari, K; Amirlak, B; Dehdashtian, A; Dehpour, AR; Haddadi, NS; Jazaeri, F; Sheikhi, M; Tavangar, SM; Zarifeh Jazaeri, S | 1 |
| Abdollahi, A; Dehpour, AR; Gharishvandi, F; Mohammad Jafari, R; Pasalar, P; Shafaroodi, H | 1 |
1 review(s) available for gr 127935 and sumatriptan
| Article | Year |
|---|---|
Control of dorsal raphé 5-HT function by multiple 5-HT(1) autoreceptors: parallel purposes or pointless plurality?
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents, Second-Generation; Autoreceptors; Dimerization; Guinea Pigs; Humans; Ion Channels; Ion Transport; Mice; Nerve Tissue Proteins; Neurons; Oxadiazoles; Piperazines; Protein Isoforms; Pyridines; Pyrimidines; Raphe Nuclei; Rats; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Second Messenger Systems; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Spiperone; Sumatriptan | 2000 |
42 other study(ies) available for gr 127935 and sumatriptan
| Article | Year |
|---|---|
Alniditan, a new 5-hydroxytryptamine1D agonist and migraine-abortive agent: ligand-binding properties of human 5-hydroxytryptamine1D alpha, human 5-hydroxytryptamine1D beta, and calf 5-hydroxytryptamine1D receptors investigated with [3H]5-hydroxytryptamin
Topics: Animals; Benzopyrans; Cattle; Cloning, Molecular; Glioma; HeLa Cells; Humans; Mice; Migraine Disorders; Propylamines; Protein Binding; Pyrimidines; Radioligand Assay; Receptors, Serotonin; Serotonin Receptor Agonists; Signal Transduction; Tritium; Tumor Cells, Cultured; Vasoconstrictor Agents | 1996 |
Identification of an amino acid residue important for binding of methiothepin and sumatriptan to the human 5-HT(1B) receptor.
Topics: Amino Acid Sequence; Amino Acids; Animals; Benzamides; Binding Sites; Binding, Competitive; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Methiothepin; Molecular Sequence Data; Mutation; Protein Binding; Pyridines; Radioligand Assay; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists; Sodium; Sumatriptan; Tritium | 1999 |
[3H]LY334370, a novel radioligand for the 5-HT1F receptor. I. In vitro characterization of binding properties.
Topics: Animals; Benzamides; Brain; Cells, Cultured; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Humans; In Vitro Techniques; Indoles; Ligands; Radioligand Assay; Rats; Receptor, Serotonin, 5-HT1F; Receptors, Serotonin; Serotonin Receptor Agonists; Transfection; Tritium | 2005 |
Differences in the effects of ketanserin and GR127935 on 5-HT-receptor mediated responses in rabbit saphenous vein and guinea-pig jugular vein.
Topics: Animals; Dose-Response Relationship, Drug; Guinea Pigs; Jugular Veins; Ketanserin; Male; Myenteric Plexus; Nifedipine; Oxadiazoles; Piperazines; Rabbits; Saphenous Vein; Serotonin; Serotonin Antagonists; Sumatriptan | 1995 |
Serotonin 5-HT1D and 5-HT1A receptors respectively mediate inhibition of glutamate release and inhibition of cyclic GMP production in rat cerebellum in vitro.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellum; Cyclic GMP; Glutamic Acid; Male; N-Methylaspartate; Oxadiazoles; Piperazines; Potassium; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1D; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Agents; Signal Transduction; Sumatriptan; Synapses; Synaptic Transmission | 1996 |
5-Hydroxytryptamine 5-HT1D receptors mediating inhibition of cyclic AMP accumulation in Madin-Darby canine kidney (MDCK) cells.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alprostadil; Animals; Cells, Cultured; Cyclic AMP; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Epithelial Cells; Epithelium; Ketanserin; Kidney Cortex; Methiothepin; Oxadiazoles; Pertussis Toxin; Piperazines; Propranolol; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Sumatriptan; Virulence Factors, Bordetella; Yohimbine | 1995 |
Ketanserin-sensitive depressant actions of 5-HT receptor agonists in the neonatal rat spinal cord.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Animals, Newborn; Depression, Chemical; Dioxanes; Dopamine Antagonists; Drug Interactions; Female; Ketanserin; Male; Motor Neurons; Oxadiazoles; Pindolol; Piperazines; Propranolol; Rats; Rats, Wistar; Receptors, Serotonin; Reflex, Monosynaptic; Serotonin; Serotonin Antagonists; Spinal Cord; Spiro Compounds; Sumatriptan | 1995 |
The activity of 5-HT1D receptor ligands at cloned human 5-HT1D alpha and 5-HT1D beta receptors.
Topics: Cyclic AMP; HeLa Cells; Humans; Metergoline; Methiothepin; Oxadiazoles; Piperazines; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan | 1995 |
Blockade of porcine carotid vascular response to sumatriptan by GR 127935, a selective 5-HT1D receptor antagonist.
Topics: Animals; Arteriovenous Anastomosis; Blood Flow Velocity; Blood Pressure; Carotid Artery, Common; Heart Rate; Oxadiazoles; Piperazines; Receptors, Serotonin; Serotonin Antagonists; Sumatriptan; Swine | 1996 |
GR127935 is a potent antagonist of the 5-HT1-like receptor mediating contraction in the canine coronary artery.
Topics: Animals; Coronary Vessels; Dogs; Drug Interactions; Ketanserin; Muscle, Smooth, Vascular; Oxadiazoles; Piperazines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Sumatriptan; Vasoconstriction | 1996 |
Influence of the endothelium and nitric oxide on the contractile responses evoked by 5-HT1D receptor agonists in the rabbit isolated saphenous vein.
Topics: Animals; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Piperazines; Rabbits; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Saphenous Vein; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan | 1996 |
Operational characteristics of the 5-HT1-like receptors mediating external carotid vasoconstriction in vagosympathectomized dogs. Close resemblance to the 5-HT1D receptor subtype.
Topics: Analysis of Variance; Animals; Blood Pressure; Carotid Artery, Common; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Male; Methysergide; Oxadiazoles; Piperazines; Receptors, Serotonin; Regional Blood Flow; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Vasoconstriction | 1996 |
Interactions of GR127935, a 5-HT(1B/D) receptor ligand, with functional 5-HT receptors.
Topics: Animals; Cats; Dose-Response Relationship, Drug; Male; Oxadiazoles; Piperazines; Rabbits; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Sumatriptan | 1997 |
Mechanism of actions of sumatriptan on coronary flow before and after endothelial dysfunction in guinea-pig isolated heart.
Topics: Animals; Coronary Circulation; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Ergolines; Guinea Pigs; Heart; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Piperazines; Saponins; Serotonin Receptor Agonists; Sumatriptan; Vasoconstrictor Agents | 1997 |
Influence of 5-HT1B/1D receptors on dopamine release in the guinea pig nucleus accumbens: a microdialysis study.
Topics: Analysis of Variance; Animals; Dopamine; Guinea Pigs; Male; Microdialysis; Nucleus Accumbens; Oxadiazoles; Piperazines; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan | 1997 |
The 5-HT1D receptor antagonist GR-127,935 prevents inhibitory effects of sumatriptan but not CP-122,288 and 5-CT on neurogenic plasma extravasation within guinea pig dura mater.
Topics: Animals; Dose-Response Relationship, Drug; Dura Mater; Electric Stimulation; Female; Guinea Pigs; Male; Oxadiazoles; Pertussis Toxin; Piperazines; Prosencephalon; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Sumatriptan; Trigeminal Nerve; Virulence Factors, Bordetella | 1997 |
Nature of 5-HT1-like receptors mediating depressor responses in vagosympathectomized rats; close resemblance to the cloned 5-ht7 receptor.
Topics: 5-Methoxytryptamine; Adrenergic beta-Agonists; Animals; Blood Pressure; Clozapine; Ergolines; Heart Rate; Isoproterenol; Lisuride; Male; Metergoline; Methiothepin; Oxadiazoles; Piperazines; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Sympathectomy | 1997 |
Involvement of 5-HT(1B/1D) and 5-HT2A receptors in 5-HT-induced contraction of endothelium-denuded rabbit epicardial coronary arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Coronary Vessels; Endothelium, Vascular; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Oxadiazoles; Pericardium; Piperazines; Rabbits; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Vasoconstrictor Agents | 1997 |
Characterization of 5-HT receptors on human pulmonary artery and vein: functional and binding studies.
Topics: Abortifacient Agents, Nonsteroidal; Adult; Aged; Benzamides; Binding Sites; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Dinoprost; Dioxanes; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Humans; Male; Middle Aged; Oxadiazoles; Piperazines; Piperidines; Pulmonary Artery; Pulmonary Veins; Pyridines; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Sumatriptan; Vasoconstrictor Agents | 1997 |
Effects of sumatriptan on coronary flow and left ventricular function in the isolated perfused guinea pig heart.
Topics: Animals; Coronary Circulation; Diastole; Dihydroergotamine; Endothelium, Vascular; Guinea Pigs; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Oxadiazoles; Oxazoles; Oxazolidinones; Perfusion; Piperazines; Rabbits; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Sumatriptan; Tryptamines; Ventricular Function, Left | 1998 |
Na(+)-dependent metabolic coupling upon 5-HT1B receptor activation by sumatriptan and related agonists.
Topics: Animals; CHO Cells; Cricetinae; Oxadiazoles; Piperazines; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Signal Transduction; Sodium; Sumatriptan; Vasoconstrictor Agents | 1998 |
Activation of recombinant h 5-HT1B and h 5-HT1D receptors stably expressed in C6 glioma cells produces increases in Ca2+-dependent K+ current.
Topics: Animals; Calcium; Cyclic AMP; Dose-Response Relationship, Drug; Glioma; Oxadiazoles; Piperazines; Potassium; Potassium Channels; Rats; Receptors, Serotonin; Recombinant Proteins; Serotonin Antagonists; Sumatriptan; Tumor Cells, Cultured | 1998 |
The selective 5-HT1B receptor inverse agonist SB-224289, potently blocks terminal 5-HT autoreceptor function both in vitro and in vivo.
Topics: Animals; Body Temperature Regulation; Cerebral Cortex; CHO Cells; Cricetinae; Dentate Gyrus; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Humans; Oxadiazoles; Piperazines; Piperidones; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Recombinant Proteins; Serotonin; Serotonin Antagonists; Spiro Compounds; Sumatriptan; Transfection | 1998 |
Pharmacological profile of the prejunctional 5-HT1 receptors mediating inhibition of sympathetic vasopressor outflow in the pithed rat.
Topics: 5-Methoxytryptamine; Animals; Blood Pressure; Central Nervous System; Oxadiazoles; Pindolol; Piperazines; Pyridines; Pyrroles; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Sympathetic Nervous System | 1998 |
Vasoconstriction in human isolated middle meningeal arteries: determining the contribution of 5-HT1B- and 5-HT1F-receptor activation.
Topics: Animals; Benzamides; Binding, Competitive; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; Humans; In Vitro Techniques; Meningeal Arteries; Oxadiazoles; Piperazines; Pyridines; Receptors, Serotonin; RNA, Messenger; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Vasoconstriction | 1999 |
Canine external carotid vasoconstriction to methysergide, ergotamine and dihydroergotamine: role of 5-HT1B/1D receptors and alpha2-adrenoceptors.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Flow Velocity; Carotid Arteries; Clonidine; Dihydroergotamine; Dogs; Ergotamine; Female; Hemodynamics; Male; Methysergide; Oxadiazoles; Phenylephrine; Piperazines; Prazosin; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Adrenergic, alpha-2; Receptors, Serotonin; Serotonin Antagonists; Sumatriptan; Vasoconstriction; Vasoconstrictor Agents; Yohimbine | 1999 |
5-Hydroxytryptamine(1A) receptor activation enhances norepinephrine release from nerves in the rabbit saphenous vein.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Adrenergic Fibers; Animals; Electric Stimulation; Ergolines; Male; Muscle Contraction; Norepinephrine; Oxadiazoles; Piperazines; Pyridines; Rabbits; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Saphenous Vein; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Synaptic Transmission | 1999 |
Functional characterization and m-RNA expression of 5-HT receptors mediating contraction in human umbilical artery.
Topics: Humans; Ketanserin; Oxadiazoles; Piperazines; Receptors, Serotonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin; Sumatriptan; Umbilical Arteries; Vasoconstriction | 1999 |
Pharmacological evidence that alpha1-and alpha2-adrenoceptors mediate vasoconstriction of carotid arteriovenous anastomoses in anaesthetized pigs.
Topics: Anesthesia; Animals; Arteriovenous Anastomosis; Azepines; Carotid Arteries; Hemodynamics; Migraine Disorders; Oxadiazoles; Phenylephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Serotonin; Sumatriptan; Swine; Vasoconstriction | 1999 |
Effects of alniditan on neurogenic oedema in the rat dura mater and on contraction of rat basilar artery.
Topics: Animals; Basilar Artery; Benzopyrans; Brain Edema; Capillary Permeability; Dose-Response Relationship, Drug; Dura Mater; Extravasation of Diagnostic and Therapeutic Materials; In Vitro Techniques; Ketanserin; Male; Oxadiazoles; Piperazines; Propylamines; Pyrimidines; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Agents; Serotonin Antagonists; Substance P; Sumatriptan; Vasoconstriction; Vasoconstrictor Agents | 1999 |
Bovine isolated middle cerebral artery contractions to antimigraine drugs.
Topics: Animals; Cattle; In Vitro Techniques; Ketanserin; Middle Cerebral Artery; Muscle Contraction; Muscle, Smooth, Vascular; Oxadiazoles; Piperazines; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Vasoconstrictor Agents | 1999 |
Phenylephrine precontraction increases the sensitivity of rabbit femoral artery to serotonin by enabling 5-HT1-like receptors.
Topics: Animals; Dose-Response Relationship, Drug; Femoral Artery; In Vitro Techniques; Oxadiazoles; Phenylephrine; Piperazines; Prazosin; Rabbits; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Specific Pathogen-Free Organisms; Sumatriptan; Vasoconstriction | 2000 |
In vivo analysis of adrenergic and serotoninergic constrictions of the rabbit saphenous vein.
Topics: Adrenergic Agents; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anesthesia; Animals; Benzazepines; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Ergolines; Imidazoles; Indoles; Injections, Intravenous; Isoindoles; Oxadiazoles; Peripheral Nervous System; Phenylephrine; Piperazines; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Receptors, Serotonin; Saphenous Vein; Serotonin; Serotonin Agents; Serotonin Receptor Agonists; Sumatriptan; Tetrahydronaphthalenes; Time Factors; Ultrasonography, Doppler; Vasoconstrictor Agents | 2000 |
Unravelling the pharmacological profile of the canine external carotid vasodilator '5-HT1-like' receptors: coexistence of sympatho-inhibitory 5-HT1B and postjunctional 5-HT7 receptors.
Topics: 5-Methoxytryptamine; Acetylcholine; Animals; Biphenyl Compounds; Blood Flow Velocity; Blood Pressure; Carotid Artery, External; Chromans; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Hemodynamics; Male; Neuromuscular Junction; Oxadiazoles; Piperazines; Piperidones; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Sumatriptan; Sympathetic Nervous System; Vasodilation | 2001 |
Serotonin-induced hypercontraction through 5-hydroxytryptamine 1B receptors in atherosclerotic rabbit coronary arteries.
Topics: Animals; Arteriosclerosis; Calcium; Coronary Vessels; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Ketanserin; Male; Oxadiazoles; Phenylephrine; Piperazines; Rabbits; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Vasoconstriction | 2001 |
Role of 5-HT1B/D receptors in canine gastric accommodation: effect of sumatriptan and 5-HT1B/D receptor antagonists.
Topics: Animals; Atropine; Benzamides; Bethanechol; Biphenyl Compounds; Dogs; Enzyme Inhibitors; Female; Gastric Emptying; NG-Nitroarginine Methyl Ester; Oxadiazoles; Parasympatholytics; Parasympathomimetics; Piperazines; Pressure; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Stomach; Sumatriptan; Vagus Nerve | 2003 |
Further characterization of the 5-HT1 receptors mediating cardiac sympatho-inhibition in pithed rats: pharmacological correlation with the 5-HT1B and 5-HT1D subtypes.
Topics: Animals; Biphenyl Compounds; Decerebrate State; Male; Norepinephrine; Oxadiazoles; Piperazines; Piperidones; Pyridines; Pyrroles; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Spiro Compounds; Sumatriptan; Sympathomimetics; Tachycardia | 2004 |
Involvement of 5-HT1B receptors in triptan-induced contractile responses in guinea-pig isolated iliac artery.
Topics: Animals; Benzamides; Brain; Carbazoles; Dinoprost; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Endothelium, Vascular; Female; Forecasting; Guinea Pigs; Iliac Artery; Indoles; Ketanserin; Male; Muscle Contraction; Muscle, Smooth; Oxadiazoles; Oxazolidinones; Piperazines; Piperidines; Pyrrolidines; Receptor, Serotonin, 5-HT1B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Sumatriptan; Triazoles; Tryptamines | 2004 |
Donitriptan decreases jugular venous oxygen saturation in rats in the absence of cranial vasoconstriction: an overlooked mechanism of antimigraine action?
Topics: Animals; Blood Gas Analysis; Cerebrovascular Circulation; Hemodynamics; Jugular Veins; Male; Migraine Disorders; Nitriles; Oxadiazoles; Oxygen; Piperazines; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Tryptamines; Vasoconstriction | 2005 |
Attenuation of serotonin-induced itch by sumatriptan: possible involvement of endogenous opioids.
Topics: Animals; Disease Models, Animal; Drug Therapy, Combination; Humans; Injections, Intradermal; Male; Mice; Naltrexone; Narcotic Antagonists; Opioid Peptides; Oxadiazoles; Piperazines; Pruritus; Quaternary Ammonium Compounds; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin Antagonists; Sumatriptan | 2018 |
Sumatriptan Increases Skin Flap Survival through Activation of 5-Hydroxytryptamine 1b/1d Receptors in Rats: The Mediating Role of the Nitric Oxide Pathway.
Topics: Animals; Graft Survival; Male; Nitric Oxide; Oxadiazoles; Piperazines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Skin Transplantation; Sumatriptan; Surgical Flaps; Vasodilator Agents | 2019 |
Involvement of 5-HT1B/1D receptors in the inflammatory response and oxidative stress in intestinal ischemia/reperfusion in rats.
Topics: Animals; Calcitonin Gene-Related Peptide; Ileum; Inflammation; Intestinal Mucosa; Male; Mesenteric Ischemia; Oxadiazoles; Oxidative Stress; Piperazines; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Reperfusion Injury; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin Antagonists; Sumatriptan | 2020 |