Compounds > gr 127935
Page last updated: 2024-09-02

gr 127935 and guanosine 5'-o-(3-thiotriphosphate)

gr 127935 has been researched along with guanosine 5'-o-(3-thiotriphosphate) in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (50.00)18.2507
2000's3 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Burton, MJ; Jones, BJ; Middlemiss, DN; Price, GW; Watson, JM1
Beer, MS; Heald, MA; McAllister, G; Stanton, JA1
Gaster, LM; Hagan, JJ; Ham, P; Joiner, GF; King, FD; Middlemiss, DN; Mulholland, KR; Price, GW; Roberts, C; Routledge, C; Selkirk, J; Slade, PD; Wyman, PA1
Beaufour, C; Evrard, A; Fabre, V; Hamon, M; Hanoun, N; Lanfumey, L; Lesch, KP; Martres, MP; Murphy, DL; Rioux, A1
Castro, ME; Mostany, R; Pazos, A1
Clarke, KL; Dawson, LA; Hagan, JJ; Langmead, CJ; Price, GW; Scott, C; Smith, PW; Starr, KR; Watson, J; Wyman, P1

Other Studies

6 other study(ies) available for gr 127935 and guanosine 5'-o-(3-thiotriphosphate)

ArticleYear
GR127935 acts as a partial agonist at recombinant human 5-HT1D alpha and 5-HT1D beta receptors.
    European journal of pharmacology, 1996, Oct-31, Volume: 314, Issue:3

    Topics: Adenylyl Cyclases; Alkylating Agents; Animals; CHO Cells; Cricetinae; Cyclic AMP; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Logistic Models; Oxadiazoles; Piperazines; Quinolines; Receptors, Serotonin; Recombinant Proteins; Serotonin Antagonists; Serotonin Receptor Agonists

1996
Pharmacological characterisation of a cloned dog 5-HT1B receptor cell line.
    European journal of pharmacology, 1998, Oct-30, Volume: 360, Issue:1

    Topics: Animals; Binding, Competitive; CHO Cells; Clone Cells; Cricetinae; Dogs; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Methiothepin; Oxadiazoles; Piperazines; Radioligand Assay; Rats; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Recombinant Fusion Proteins; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfur Radioisotopes; Tritium

1998
The selective 5-HT1B receptor inverse agonist SB-224289, potently blocks terminal 5-HT autoreceptor function both in vitro and in vivo.
    Annals of the New York Academy of Sciences, 1998, Dec-15, Volume: 861

    Topics: Animals; Body Temperature Regulation; Cerebral Cortex; CHO Cells; Cricetinae; Dentate Gyrus; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Humans; Oxadiazoles; Piperazines; Piperidones; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Recombinant Proteins; Serotonin; Serotonin Antagonists; Spiro Compounds; Sumatriptan; Transfection

1998
Altered expression and functions of serotonin 5-HT1A and 5-HT1B receptors in knock-out mice lacking the 5-HT transporter.
    The European journal of neuroscience, 2000, Volume: 12, Issue:7

    Topics: Animals; Autoreceptors; Binding, Competitive; Brain Chemistry; Carrier Proteins; Citalopram; Dipeptides; Down-Regulation; Gene Expression; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hydroxyindoleacetic Acid; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Oxadiazoles; Piperazines; Pyridines; Pyrimidines; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Spiro Compounds; Substantia Nigra; Sulfur Radioisotopes; Synaptic Transmission; Tritium

2000
Autoradiographic characterisation of [35S]GTPgammaS binding stimulation mediated by 5-HT1B receptor in postmortem human brain.
    Neuropharmacology, 2005, Volume: 48, Issue:1

    Topics: Aged; Autoradiography; Binding, Competitive; Biphenyl Compounds; Brain; Dipeptides; Drug Interactions; Female; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Male; Middle Aged; Oxadiazoles; Piperazines; Piperidones; Postmortem Changes; Protein Binding; Pyridines; Pyrroles; Receptor, Serotonin, 5-HT1B; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Sulfur Isotopes

2005
SB-616234-A (1-[6-(cis-3,5-dimethylpiperazin-1-yl)-2,3-dihydro-5-methoxyindol-1-yl]-1-[2'methyl-4'-(5-methyl-1,2,3-oxadiazol-3-yl)biphenyl-4-yl]methanone hydrochloride): a novel, potent and selective 5-HT1B receptor antagonist.
    Neuropharmacology, 2006, Volume: 50, Issue:8

    Topics: Analysis of Variance; Animals; Binding, Competitive; Cerebral Cortex; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Humans; In Vitro Techniques; Indoles; Membrane Potentials; Neurons; Oxadiazoles; Patch-Clamp Techniques; Piperazines; Protein Binding; Rats; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Serotonin Antagonists; Sulfur Isotopes; Tritium

2006