Page last updated: 2024-08-25

gr 117289 and angiotensin ii

gr 117289 has been researched along with angiotensin ii in 9 studies

Research

Studies (9)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	7 (77.78)	18.2507
2000's	2 (22.22)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Barnes, JC; Clark, KL; Dowle, MD; Drew, GM; Marshall, FH; Michel, A; Middlemiss, D; Robertson, MJ; Ross, BC; Scopes, D	1
Drew, GM; Gardner, CJ; Hilditch, A; Hunt, AA; Middlemiss, D; Polley, J; Robertson, MJ; Ross, BC; Travers, A; Twissell, DJ	1
Barnes, JC; Clark, SA; Marshall, FH; Michel, AD	1
Clark, KL; Drew, GM; Robertson, MJ	1
Ciccocioppo, R; Cirillo, R; Massi, M; Polidori, C; Pompei, P	1
Benjamin, N; Lyons, D; Nixon, A; Smith, J; Webster, J; Young, MM	1
Broughton Pipkin, F; Pratten, MK; Tebbs, C	1
Floten, HS; Furnary, AP; He, GW; Liu, MH; Yim, AP	1
Broughton Pipkin, F; Hunter, MG; Shuttleworth, G	1

Trials

1 trial(s) available for gr 117289 and angiotensin ii

Article	Year
Effect of the non peptide angiotensin II antagonist, GR117289C on the vasoconstrictor actions of angiotensin II in the human forearm. British journal of clinical pharmacology, 1997, Volume: 43, Issue:3 Topics: Administration, Oral; Adult; Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Blood Pressure; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Forearm; Heart Rate; Humans; Male; Nicotinic Acids; Tetrazoles; Vasoconstriction; Vasoconstrictor Agents	1997

Article

Year

Effect of the non peptide angiotensin II antagonist, GR117289C on the vasoconstrictor actions of angiotensin II in the human forearm.

British journal of clinical pharmacology, 1997, Volume: 43, Issue:3

Topics: Administration, Oral; Adult; Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Blood Pressure; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Forearm; Heart Rate; Humans; Male; Nicotinic Acids; Tetrazoles; Vasoconstriction; Vasoconstrictor Agents

1997

Other Studies

8 other study(ies) available for gr 117289 and angiotensin ii

Article	Year
Pharmacological profile of GR117289 in vitro: a novel, potent and specific non-peptide angiotensin AT1 receptor antagonist. British journal of pharmacology, 1992, Volume: 107, Issue:4 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Binding Sites; Biphenyl Compounds; Cattle; Cerebellum; Dose-Response Relationship, Drug; Imidazoles; In Vitro Techniques; Liver; Losartan; Muscle Contraction; Muscle, Smooth, Vascular; Nicotinic Acids; Rabbits; Radioligand Assay; Receptors, Angiotensin; Tetrazoles; Vasoconstriction	1992
Cardiovascular effects of GR117289, a novel angiotensin AT1 receptor antagonist. British journal of pharmacology, 1994, Volume: 111, Issue:1 Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Callithrix; Dogs; Dose-Response Relationship, Drug; Hypertension; Hypertension, Renovascular; Injections, Intra-Arterial; Male; Nicotinic Acids; Rats; Rats, Inbred SHR; Tetrazoles	1994
Binding of angiotensin antagonists to rat liver and brain membranes measured ex vivo. British journal of pharmacology, 1993, Volume: 109, Issue:3 Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Biphenyl Compounds; Blood-Brain Barrier; Brain; Imidazoles; In Vitro Techniques; Iodine Radioisotopes; Liver; Losartan; Male; Membranes; Nicotinic Acids; Pyridines; Rats; Receptors, Angiotensin; Saralasin; Tetrazoles	1993
Role of angiotensin AT1 and AT2 receptors in mediating the renal effects of angiotensin II in the anaesthetized dog. British journal of pharmacology, 1993, Volume: 109, Issue:1 Topics: Anesthesia; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Dogs; Female; Glomerular Filtration Rate; Imidazoles; Kidney; Kidney Function Tests; Male; Nicotinic Acids; Pyridines; Receptors, Angiotensin; Renal Circulation; Tetrazoles	1993
Functional evidence for the ability of angiotensin AT1 receptor antagonists to cross the blood-brain barrier in rats. European journal of pharmacology, 1996, Jul-04, Volume: 307, Issue:3 Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Blood-Brain Barrier; Carbachol; Dose-Response Relationship, Drug; Drinking; Imidazoles; Injections, Intraperitoneal; Injections, Intraventricular; Losartan; Male; Nicotinic Acids; Pyrimidinones; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Tetrazoles; Thiophenes	1996
Angiotensin II is a growth factor in the peri-implantation rat embryo. Journal of anatomy, 1999, Volume: 195 ( Pt 1) Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blastocyst; Culture Techniques; Embryonic and Fetal Development; Female; Growth Substances; Imidazoles; Nicotinic Acids; Pyridines; Rats; Rats, Wistar; Statistics, Nonparametric; Tetrazoles	1999
Inhibition of vasoconstriction by angiotensin receptor antagonist GR117289C in arterial grafts. The Annals of thoracic surgery, 2000, Volume: 70, Issue:6 Topics: Aged; Angiotensin II; Coronary Artery Bypass; Culture Techniques; Dose-Response Relationship, Drug; Female; Humans; Internal Mammary-Coronary Artery Anastomosis; Male; Mammary Arteries; Middle Aged; Nicotinic Acids; Receptors, Angiotensin; Tetrazoles; Vasoconstriction; Vasoconstrictor Agents	2000
Autoradiographic determination of angiotensin II receptors in prepubertal and postpubertal pig ovarian tissue. Reproduction (Cambridge, England), 2001, Volume: 122, Issue:5 Topics: Absorptiometry, Photon; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Binding, Competitive; Female; Granulosa Cells; Image Processing, Computer-Assisted; Imidazoles; Immunohistochemistry; Nicotinic Acids; Ovary; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sexual Maturation; Swine; Tetrazoles	2001