Compounds > gpa 1734

Page last updated: 2024-09-04

gpa 1734 and 2h-benzo(a)quinolizin-2-ol, 2-ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-

gpa 1734 has been researched along with 2h-benzo(a)quinolizin-2-ol, 2-ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy- in 9 studies

Compound Research Comparison

Studies (gpa 1734)	Trials (gpa 1734)	Recent Studies (post-2010) (gpa 1734)	Studies (2h-benzo(a)quinolizin-2-ol, 2-ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-)	Trials (2h-benzo(a)quinolizin-2-ol, 2-ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-)	Recent Studies (post-2010) (2h-benzo(a)quinolizin-2-ol, 2-ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-)
9	0	0	97	0	8

Protein Interaction Comparison

Protein	Taxonomy	gpa 1734 (IC50)	2h-benzo(a)quinolizin-2-ol, 2-ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy- (IC50)
Synaptic vesicular amine transporter	Homo sapiens (human)		0.154

Research

Studies (9)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (44.44)	18.7374
1990's	5 (55.56)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Dunn, MA; Hait, PK; Maragoudakis, ME	1
Kalinsky, HJ; Maragoudakis, ME; Wasvary, J	1
Karakiulakis, G; Maragoudakis, ME; Missirlis, E	1
Maragoudakis, ME; Panoutsacopoulou, M; Sarmonika, M	2
Grant, DS; Haralabopoulos, GC; Kleinman, HK; Lelkes, PI; Maragoudakis, ME; Papaioannou, SP	1
Bastakis, M; Karakiulakis, GD; Maragoudakis, ME; Missirlis, E; Sarmonica, M; Tsopanoglou, N	1
Karakiulakis, G; Maragoudakis, ME; Misevic, GN; Papakonstantinou, E	1
Haralabopoulos, GC; Maragoudakis, ME; Pipili-Synetos, E; Tsopanoglou, NE	1

Other Studies

9 other study(ies) available for gpa 1734 and 2h-benzo(a)quinolizin-2-ol, 2-ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-

Article	Year
Liver collagen hydroxylation in murine schistosomiasis. Biochimica et biophysica acta, 1978, Jan-18, Volume: 538, Issue:2 Topics: 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-; Animals; Iron Chelating Agents; Liver Cirrhosis; Mice; Procollagen; Procollagen-Proline Dioxygenase; Schistosoma mansoni; Schistosomiasis	1978
Effects of L-dopa, GPA 1734 and other agents on basement membrane biosynthesis. The Journal of pharmacology and experimental therapeutics, 1978, Volume: 204, Issue:2 Topics: 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-; Animals; Basement Membrane; Collagen; Diabetes Mellitus; Female; Hormones; In Vitro Techniques; Levodopa; Microtubules; Pregnancy; Procollagen-Proline Dioxygenase; Prostaglandins; Quinolizines; Rats; Skin	1978
Antitumor effect of GPA1734 in rat Walker 256 carcinoma. Investigational new drugs, 1990, Volume: 8, Issue:2 Topics: 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-; Animals; Antineoplastic Agents; Basement Membrane; Body Weight; Carcinoma 256, Walker; Collagen; Injections, Intraperitoneal; Male; Neoplasm Transplantation; Quinolizines; Rats; Rats, Inbred Strains	1990
Inhibition of basement membrane biosynthesis prevents angiogenesis. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 244, Issue:2 Topics: 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-; Allantois; Animals; Basement Membrane; Chick Embryo; Chorion; Collagen; In Vitro Techniques; Iron; Neovascularization, Pathologic; Protein Biosynthesis	1988
Rate of basement membrane biosynthesis as an index to angiogenesis. Tissue & cell, 1988, Volume: 20, Issue:4 Topics: 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-; Allantois; Animals; Basement Membrane; Chick Embryo; Chorion; Collagen; DNA; Hyaluronic Acid; Neovascularization, Pathologic; Protein Biosynthesis	1988
Inhibitors of basement membrane collagen synthesis prevent endothelial cell alignment in matrigel in vitro and angiogenesis in vivo. Laboratory investigation; a journal of technical methods and pathology, 1994, Volume: 71, Issue:4 Topics: 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-; Animals; Antineoplastic Agents; Basement Membrane; Bridged-Ring Compounds; Cell Adhesion; Cell Division; Cell Survival; Cells, Cultured; Collagen; Dose-Response Relationship, Drug; Drug Combinations; Endothelium, Vascular; Female; Humans; Laminin; Mice; Neovascularization, Pathologic; Norbornanes; Phenotype; Proteoglycans; Thiocarbamates; Thiones	1994
Basement membrane biosynthesis as a target for developing inhibitors of angiogenesis with anti-tumor properties. Kidney international, 1993, Volume: 43, Issue:1 Topics: 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-; Allantois; Animals; Antineoplastic Agents; Basement Membrane; Bridged-Ring Compounds; Carcinoma 256, Walker; Chick Embryo; Chorion; Collagen; In Vitro Techniques; Male; Neovascularization, Pathologic; Norbornanes; Rats; Thiocarbamates; Thiones; Tumor Cells, Cultured	1993
Expression of type IV collagen-degrading activity during early embryonal development in the sea urchin and the arresting effects of collagen synthesis inhibitors on embryogenesis. Journal of cellular biochemistry, 1993, Volume: 52, Issue:1 Topics: 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-; Animals; Blastocyst; Bridged-Ring Compounds; Chromatography, Gel; Collagen; Embryo, Nonmammalian; Gastrula; Norbornanes; Sea Urchins; Thiocarbamates; Thiones	1993
Validation of collagenous protein synthesis as an index for angiogenesis with the use of morphological methods. Microvascular research, 1995, Volume: 50, Issue:2 Topics: 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-; Animals; Antineoplastic Agents; Biomarkers; Bridged-Ring Compounds; Chick Embryo; Chorion; Collagen; Neovascularization, Physiologic; Norbornanes; Phorbol Esters; Thiocarbamates; Thiones; Thrombin	1995