gossypol has been researched along with zidovudine in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, G; Li, J; Ouyang, W; Pan, W; Tien, P; Wu, S; Yang, J; Yu, R; Zhang, F | 1 |
| Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ | 1 |
| Chen, G; Li, JR; Li, LL; Ouyang, WJ; Wu, SW; Yang, J; Yang, JX; Yu, R; Zhang, F | 1 |
| August, EM; Eriksson, BF; Griffith, BP; Huang, LA; Lin, TS; Prusoff, WH; Schinazi, R; Zheng, DK | 1 |
| Mills, RG; Royer, RE; Vander Jagt, DL; Young, SA | 1 |
| Birks, E; Lin, TS; Pivazyan, A; Prusoff, W; Sun, AS | 1 |
| Deng, JP; Fang, ZZ; Hu, CM; Li, G; Li, HR; Tu, YY; Wang, L; Yao, JJ; Yuan, J; Zhang, YS | 1 |
1 review(s) available for gossypol and zidovudine
| Article | Year |
|---|---|
Empirical and rational approaches for development of inhibitors of the human immunodeficiency virus--HIV-1.
Topics: Amino Acid Sequence; Animals; Antiviral Agents; Drug Design; Gossypol; HIV Infections; HIV-1; Humans; Hydrocarbons, Halogenated; Molecular Sequence Data; Protease Inhibitors; Pyrimidine Nucleosides; Stereoisomerism; Structure-Activity Relationship; Virus Replication; Zidovudine | 1993 |
7 other study(ies) available for gossypol and zidovudine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Synthesis and antiviral activities of novel gossypol derivatives.
Topics: Anti-HIV Agents; Antiviral Agents; Gossypol; HIV-1; Humans; Influenza A Virus, H5N1 Subtype; Inhibitory Concentration 50; Models, Molecular; Molecular Structure | 2012 |
Identification of potent Yes1 kinase inhibitors using a library screening approach.
Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
Synthesis and biological evaluation of water-soluble derivatives of chiral gossypol as HIV fusion inhibitors targeting gp41.
Topics: Binding Sites; Drug Design; Gossypol; HIV Envelope Protein gp41; HIV Fusion Inhibitors; HIV-1; Humans; Hydrogen Bonding; Inhibitory Concentration 50; Molecular Docking Simulation; Protein Structure, Tertiary; Solubility; Stereoisomerism; Virus Replication; Water | 2018 |
Selective inhibition of human immunodeficiency virus type 1 replication by the (-) but not the (+) enantiomer of gossypol.
Topics: Cells, Cultured; Gossypol; HIV-1; Humans; Neutrophils; Stereoisomerism; Virus Replication; Zidovudine | 1989 |
Comparison of the antiviral activities of 3'-azido-3'-deoxythymidine (AZT) and gossylic iminolactone (GIL) against clinical isolates of HIV-1.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Dose-Response Relationship, Drug; Gossypol; HIV Reverse Transcriptase; HIV-1; Humans; Reverse Transcriptase Inhibitors; Zidovudine | 1995 |
Gossypol exhibits a strong influence towards UDP-glucuronosyltransferase (UGT) 1A1, 1A9 and 2B7-mediated metabolism of xenobiotics and endogenous substances.
Topics: Enzyme Inhibitors; Estradiol; Glucuronides; Glucuronosyltransferase; Gossypol; Humans; Isoenzymes; Kinetics; Microsomes, Liver; Propofol; Substrate Specificity; Uridine Diphosphate Glucuronic Acid; Xenobiotics; Zidovudine | 2012 |