Compounds > gossypol

gossypol and temozolomide

gossypol has been researched along with temozolomide in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (62.50)24.3611
2020's3 (37.50)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Kögel, D; Lang, V; Ronellenfitsch, MW; Seifert, V; Senft, C; Steinbach, JP; Voss, V1
Li, S; Liu, Y; Sun, P; Ying, H1
Adamski, V; Adelung, R; Ceynowa, F; Hattermann, K; Held-Feindt, J; Lucius, R; Schmitt, C; Synowitz, M1
Jang, H; Jeon, JH; Kang, SG; Kang, SW; Kim, DK; Kim, HY; Kim, SY; Lee, BI; Shim, JK1
Adamski, V; Adelung, R; Hattermann, K; Held-Feindt, J; Lucius, R; Rasch, F; Schmitt, C; Synowitz, M1
Caylioglu, D; Held-Feindt, J; Hellmold, D; Kubelt, C; Meyer, RJ; Synowitz, M1
Adelung, R; Beckinger, S; Daunke, T; Haag, J; Hauck, M; Held-Feindt, J; Hellmold, D; Janssen, O; Kubelt, C; Lucius, R; Schütt, F; Sebens, S; Synowitz, M1

Other Studies

8 other study(ies) available for gossypol and temozolomide

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
The pan-Bcl-2 inhibitor (-)-gossypol triggers autophagic cell death in malignant glioma.
    Molecular cancer research : MCR, 2010, Volume: 8, Issue:7

    Topics: Animals; Apoptosis; Autophagy; Caspases; Cell Line, Tumor; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Enzyme Activation; Glioma; Gossypol; Humans; Mitochondria; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Signal Transduction; Temozolomide; Transfection; Tumor Suppressor Proteins

2010
Action of db-cAMP on the bystander effect and chemosensitivity through connexin 43 and Bcl-2-mediated pathways in medulloblastoma cells.
    Oncology reports, 2012, Volume: 28, Issue:3

    Topics: Animals; Antineoplastic Agents; Bucladesine; Bystander Effect; Cell Line, Tumor; Cell Survival; Cerebellar Neoplasms; Connexin 43; Dacarbazine; Drug Screening Assays, Antitumor; Drug Synergism; Gap Junctions; Gossypol; Humans; Medulloblastoma; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-bcl-2; Rats; Signal Transduction; Simplexvirus; Temozolomide; Teniposide; Thymidine Kinase

2012
Effects of sequentially applied single and combined temozolomide, hydroxychloroquine and AT101 treatment in a long-term stimulation glioblastoma in vitro model.
    Journal of cancer research and clinical oncology, 2018, Volume: 144, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Growth Processes; Cell Line, Tumor; Dacarbazine; Drug Administration Schedule; Drug Synergism; Glioblastoma; Gossypol; Humans; Hydroxychloroquine; Temozolomide

2018
Gossypol Suppresses Growth of Temozolomide-Resistant Glioblastoma Tumor Spheres.
    Biomolecules, 2019, 10-10, Volume: 9, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Cell Proliferation; Cell Survival; Combined Modality Therapy; Contraceptive Agents, Male; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Glioblastoma; Gossypol; Humans; Male; Membrane Potential, Mitochondrial; Molecular Docking Simulation; Temozolomide; Tumor Cells, Cultured

2019
Establishment of a glioblastoma in vitro (in)complete resection dual co-culture model suitable for drug testing.
    Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft, 2020, Volume: 228

    Topics: Analysis of Variance; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Astrocytes; Brain; Coculture Techniques; Glioblastoma; Gossypol; Humans; Microglia; Temozolomide

2020
Effects of the Anti-Tumorigenic Agent AT101 on Human Glioblastoma Cells in the Microenvironmental Glioma Stem Cell Niche.
    International journal of molecular sciences, 2021, Mar-30, Volume: 22, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Glioblastoma; Glioma; Gossypol; Humans; Neoplastic Stem Cells; Signal Transduction; Stem Cell Niche; Temozolomide; Tumor Microenvironment

2021
Sequential Treatment with Temozolomide Plus Naturally Derived AT101 as an Alternative Therapeutic Strategy: Insights into Chemoresistance Mechanisms of Surviving Glioblastoma Cells.
    International journal of molecular sciences, 2023, May-22, Volume: 24, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Gossypol; Humans; Neoplasm Recurrence, Local; Temozolomide; TOR Serine-Threonine Kinases

2023