gossypol and phenformin

gossypol has been researched along with phenformin in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (71.43)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Hong, KM; Jang, H; Kang, JH; Kim, SY; Lee, C; Lee, JS; Lee, SH; Nam, B; Seong, TW; Son, J1
Chang, JH; Choi, J; Kang, JH; Kang, SG; Kim, SY; Park, J; Shim, JK1
Kang, JH; Kim, SY; Lee, JS; Lee, S; Lee, SH; Seo, J; Song, J1
Cheong, JH; Kang, JH; Kim, SH; Kim, SY; Lee, JS; Lee, S; Lee, SH1
Jang, H; Kang, JH; Kim, HY; Kim, SY; Lee, H; Lee, JS; Lee, SH; Park, JB; Song, J; Woo, SM1
Han, SS; Hong, EK; Jang, H; Jeon, Y; Kim, HY; Kim, SY; Lee, H; Lee, JS; Lee, WJ; Park, SJ; Song, J; Woo, SM1

Other Studies

7 other study(ies) available for gossypol and phenformin

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Aldehyde dehydrogenase inhibition combined with phenformin treatment reversed NSCLC through ATP depletion.
    Oncotarget, 2016, Aug-02, Volume: 7, Issue:31

    Topics: Action Potentials; Adenosine Triphosphate; Aldehyde Dehydrogenase; Animals; Aspartic Acid; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cytosol; Female; Gossypol; Humans; Lung Neoplasms; Malates; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; NAD; NADP; Neoplasm Transplantation; Oxidative Phosphorylation; Oxidoreductases Acting on CH-NH Group Donors; Phenformin; RNA, Small Interfering

2016
Regulation of bioenergetics through dual inhibition of aldehyde dehydrogenase and mitochondrial complex I suppresses glioblastoma tumorspheres.
    Neuro-oncology, 2018, 06-18, Volume: 20, Issue:7

    Topics: Adenosine Triphosphate; Aldehyde Dehydrogenase; Animals; Biomarkers, Tumor; Brain Neoplasms; Cell Proliferation; Contraceptive Agents, Male; Electron Transport Complex I; Energy Metabolism; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioblastoma; Gossypol; Humans; Hypoglycemic Agents; Male; Mice; Mice, Nude; Mitochondria; Neoplasm Invasiveness; Neoplastic Stem Cells; Oxidative Phosphorylation; Phenformin; Prognosis; Survival Rate; Xenograft Model Antitumor Assays

2018
Targeting Mitochondrial Oxidative Phosphorylation Abrogated Irinotecan Resistance in NSCLC.
    Scientific reports, 2018, 10-24, Volume: 8, Issue:1

    Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Death; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; Gossypol; Heterografts; Humans; Irinotecan; Mice; Mitochondria; Oxidative Phosphorylation; Phenformin

2018
Gastric cancer depends on aldehyde dehydrogenase 3A1 for fatty acid oxidation.
    Scientific reports, 2019, 11-08, Volume: 9, Issue:1

    Topics: Adenosine Triphosphate; Aldehyde Dehydrogenase; Animals; Cell Line, Tumor; Cell Proliferation; Fatty Acids; Female; Gene Knockdown Techniques; Gossypol; Humans; Male; Mice; Oxidation-Reduction; Phenformin; Stomach Neoplasms

2019
Targeting Oxidative Phosphorylation Reverses Drug Resistance in Cancer Cells by Blocking Autophagy Recycling.
    Cells, 2020, 09-01, Volume: 9, Issue:9

    Topics: Aldehyde Dehydrogenase; Animals; Antineoplastic Agents; Autophagy; Drug Resistance, Neoplasm; Drug Synergism; Electron Transport Complex I; Gossypol; HT29 Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Neoplasms; Oxidative Phosphorylation; Phenformin; Xenograft Model Antitumor Assays

2020
Overall survival of pancreatic ductal adenocarcinoma is doubled by
    Theranostics, 2021, Volume: 11, Issue:7

    Topics: Aldehyde Dehydrogenase; Aldehydes; Animals; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation, Neoplastic; Gossypol; Homeodomain Proteins; Humans; Lipid Peroxidation; Mice; Mice, Knockout; Mice, Nude; Oxidative Phosphorylation; Pancreatic Neoplasms; Phenformin; Proto-Oncogene Proteins p21(ras); Signal Transduction; Survival Analysis; Trans-Activators; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays

2021