gossypol has been researched along with nitrophenols in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 10 (71.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Azmi, AS; Mohammad, RM | 1 |
| Tang, Y; Wu, XM; Zhang, DY | 1 |
| Kang, MH; Reynolds, CP | 1 |
| Chen, NL; Fluchel, MN; Goldsmith, KC; Goyal, B; Hogarty, MD; Lestini, BJ; Liu, X; Pawel, BR | 1 |
| Bhumbla, A; Goldsmith, KC; Gross, M; Hogarty, MD; Ip, L; Lestini, BJ; Liu, X; Zhang, X; Zhao, H | 1 |
| Al-Harbi, S; Almasan, A; Choudhary, GS; Mazumder, S | 1 |
| Figg, WD; Hall, C; Kang, MH; Price, DK; Troutman, SM | 1 |
| Bates, DJ; Danilov, AV; Eastman, A; Soderquist, R | 1 |
| Das, SK; Dash, R; Fisher, PB; Maji, S; Panda, S; Pattanaik, L; Pellecchia, M; Quinn, BA; Samal, SK; Sarkar, D | 1 |
| Andreeff, M; Konopleva, M; Pan, R; Pellecchia, M; Reed, JC; Ruvolo, PP; Ruvolo, VR; Wei, J | 1 |
| Bello, M; Correa-Basurto, J; Zacarías-Lara, OJ | 1 |
| Antonietti, P; Burger, MC; Fulda, S; Gessler, F; Hehlgans, S; Kögel, D; Linder, B; Mildenberger, IC; Mittelbronn, M; Rödel, F; Steinbach, JP | 1 |
| Carroll, SL; Gibson, LM; Graham, CD; Kaza, N; Klocke, BJ; Pruitt, HC; Roth, KA; Shevde, LA | 1 |
| Han, Z; He, J; Li, Y; Liang, J | 1 |
5 review(s) available for gossypol and nitrophenols
| Article | Year |
|---|---|
Non-peptidic small molecule inhibitors against Bcl-2 for cancer therapy.
Topics: Aniline Compounds; Animals; Apoptosis; Benzamides; Binding Sites; Biphenyl Compounds; Gossypol; Humans; Indoles; Lymphoma; Models, Molecular; Neoplasms; Nitrophenols; Piperazines; Protein Structure, Tertiary; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Sulfonamides; Sulfones | 2009 |
[Progress in small-molecule inhibitors of Bcl-2 family proteins].
Topics: Antimycin A; Antineoplastic Agents; Apoptosis; bcl-X Protein; Benzopyrans; Biphenyl Compounds; Cell Line, Tumor; Drug Design; Drugs, Chinese Herbal; Gossypol; Humans; Nitriles; Nitrophenols; Piperazines; Proto-Oncogene Proteins c-bcl-2; Structure-Activity Relationship; Sulfonamides; Thiazoles; Thiazolidinediones | 2008 |
Bcl-2 inhibitors: targeting mitochondrial apoptotic pathways in cancer therapy.
Topics: Aniline Compounds; Animals; Antineoplastic Agents; Apoptosis; Biphenyl Compounds; Gossypol; Humans; Indoles; Mitochondria; Neoplasms; Nitrophenols; Piperazines; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Sulfonamides; Thionucleotides | 2009 |
Bcl-2 family of proteins as therapeutic targets in genitourinary neoplasms.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biphenyl Compounds; Clinical Trials as Topic; Gossypol; Humans; Molecular Targeted Therapy; Nitrophenols; Piperazines; Proto-Oncogene Proteins c-bcl-2; Sulfonamides; Thionucleotides; Urogenital Neoplasms | 2013 |
Drugs and Clinical Approaches Targeting the Antiapoptotic Protein: A Review.
Topics: Aniline Compounds; Antineoplastic Agents; Apoptosis; Biphenyl Compounds; Cell Line, Tumor; Gossypol; Humans; Lymphoma, B-Cell; Nitrophenols; Piperazines; Proto-Oncogene Proteins c-bcl-2; Sulfonamides; Thionucleotides | 2019 |
9 other study(ies) available for gossypol and nitrophenols
| Article | Year |
|---|---|
Mcl1 downregulation sensitizes neuroblastoma to cytotoxic chemotherapy and small molecule Bcl2-family antagonists.
Topics: Biphenyl Compounds; Cell Line, Tumor; Cell Proliferation; Combined Modality Therapy; Down-Regulation; Gene Silencing; Gossypol; Humans; Microscopy, Phase-Contrast; Myeloid Cell Leukemia Sequence 1 Protein; Neuroblastoma; Nitrophenols; Piperazines; Proto-Oncogene Proteins c-bcl-2; RNA Interference; Sulfonamides; Transfection | 2009 |
BH3 response profiles from neuroblastoma mitochondria predict activity of small molecule Bcl-2 family antagonists.
Topics: Apoptosis; Biphenyl Compounds; Cell Line; Cell Line, Tumor; Cytochromes c; Gossypol; Humans; Immunoblotting; Immunoprecipitation; Mitochondria; Neuroblastoma; Nitrophenols; Peptide Fragments; Piperazines; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Sulfonamides | 2010 |
Mcl-1 Phosphorylation defines ABT-737 resistance that can be overcome by increased NOXA expression in leukemic B cells.
Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Biphenyl Compounds; Cell Line, Tumor; Drug Resistance, Neoplasm; Gossypol; Humans; Indoles; Leukemia, B-Cell; Membrane Proteins; Myeloid Cell Leukemia Sequence 1 Protein; Nitrophenols; Phosphorylation; Piperazines; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyrroles; RNA Interference; RNA, Small Interfering; Sulfonamides | 2012 |
Gossypol overcomes stroma-mediated resistance to the BCL2 inhibitor ABT-737 in chronic lymphocytic leukemia cells ex vivo.
Topics: Biphenyl Compounds; Contraceptive Agents, Male; Drug Resistance, Neoplasm; Gossypol; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Nitrophenols; Piperazines; Proto-Oncogene Proteins c-bcl-2; Stromal Cells; Sulfonamides; Tumor Cells, Cultured | 2013 |
Mcl-1 is an important therapeutic target for oral squamous cell carcinomas.
Topics: 4-Nitroquinoline-1-oxide; Animals; Apoptosis; Apoptosis Regulatory Proteins; Autophagy-Related Protein 5; Autophagy-Related Protein 7; bcl-X Protein; Beclin-1; Biphenyl Compounds; Carcinoma, Squamous Cell; Celecoxib; Cell Line, Tumor; Cyclooxygenase 2 Inhibitors; Female; Gossypol; Humans; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Microtubule-Associated Proteins; Mitophagy; Mouth Neoplasms; Myeloid Cell Leukemia Sequence 1 Protein; Nitrophenols; Piperazines; Proto-Oncogene Proteins; Quinolones; Random Allocation; RNA Interference; RNA, Small Interfering; Sulfonamides; Ubiquitin-Activating Enzymes; Xenograft Model Antitumor Assays | 2015 |
Inhibition of Mcl-1 with the pan-Bcl-2 family inhibitor (-)BI97D6 overcomes ABT-737 resistance in acute myeloid leukemia.
Topics: Animals; Apoptosis; Biphenyl Compounds; Blotting, Western; Cell Proliferation; Drug Resistance, Neoplasm; Female; Flow Cytometry; Gossypol; Humans; Immunoenzyme Techniques; Immunoprecipitation; Leukemia, Myeloid, Acute; Mesenchymal Stem Cells; Mice; Mice, Inbred NOD; Mice, SCID; Myeloid Cell Leukemia Sequence 1 Protein; Naphthoquinones; Neoplastic Stem Cells; Nitrophenols; Piperazines; Proto-Oncogene Proteins c-bcl-2; Stem Cells; Sulfonamides; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2015 |
Exploring the conformational and binding properties of unphosphorylated/phosphorylated monomeric and trimeric Bcl-2 through docking and molecular dynamics simulations.
Topics: Aniline Compounds; Binding Sites; Biphenyl Compounds; Gossypol; Humans; Ligands; Molecular Docking Simulation; Molecular Dynamics Simulation; Nitrophenols; Paclitaxel; Phosphorylation; Piperazines; Principal Component Analysis; Protein Binding; Protein Domains; Protein Multimerization; Protein Structure, Secondary; Proto-Oncogene Proteins c-bcl-2; Sulfonamides; Thermodynamics | 2016 |
Interference with the HSF1/HSP70/BAG3 Pathway Primes Glioma Cells to Matrix Detachment and BH3 Mimetic-Induced Apoptosis.
Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; Apoptosis Regulatory Proteins; bcl-X Protein; Biomarkers, Tumor; Biphenyl Compounds; Cell Adhesion; Cell Line, Tumor; DNA-Binding Proteins; Drug Resistance, Neoplasm; Gene Expression; Gene Knockdown Techniques; Glioma; Gossypol; Heat Shock Transcription Factors; HSP70 Heat-Shock Proteins; Humans; Inhibitor of Apoptosis Proteins; Mice; Molecular Mimicry; NF-kappa B; Nitrophenols; Piperazines; Protein Binding; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering; Signal Transduction; Sulfonamides; Survivin; Transcription Factors | 2017 |
BH3 mimetics suppress CXCL12 expression in human malignant peripheral nerve sheath tumor cells.
Topics: Antineoplastic Agents; Biphenyl Compounds; Cell Line, Tumor; Chemokine CXCL12; Down-Regulation; Gene Expression Regulation, Neoplastic; Gossypol; Humans; Indoles; Molecular Mimicry; Neurilemmoma; Nitrophenols; Piperazines; Poly (ADP-Ribose) Polymerase-1; Protein Binding; Protein Interaction Domains and Motifs; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Sulfonamides | 2017 |