Compounds > gossypol

gossypol and cytochrome c-t

gossypol has been researched along with cytochrome c-t in 11 studies

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	8 (72.73)	29.6817
2010's	3 (27.27)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Fujii, M; Hou, DX; Imamura, I; Ose, T; Takeshita, T; Tanigawa, S; Tong, X; Uto, T	1
Aboukameel, A; Al-Katib, A; Chen, B; Chen, J; Mohammad, RM; Wang, S; Wu, X	1
Banerjee, S; Chen, J; Mohammad, RM; Sarkar, FH; Wang, S; Wu, X	1
Chen, Q; Chen, Y; Du, G; Hao, X; He, H; Lei, X; Liao, X; Mao, J; Mehrpour, M; Qu, H; Wang, X; Xia, B; Yu, W; Zong, W	1
Chen, YC; Ko, CH; Lin, CW; Shen, SC; Yang, LY	1
Chen, X; Fu, J; Li, H; Li, J; Li, Y; Liu, H; Liu, Y; Meng, Y	1
Hu, ZY; Jiang, WQ; Li, ZM; Lin, XB; Sun, J; Xian, LJ; Yang, DJ; Zhou, NN	1
Hu, ZY; Jiang, WQ; Li, ZM; Sun, J; Yang, DJ; Zeng, ZL	1
Bhumbla, A; Goldsmith, KC; Gross, M; Hogarty, MD; Ip, L; Lestini, BJ; Liu, X; Zhang, X; Zhao, H	1
Hsiao, WT; Jow, GM; Lee, YJ; Tien, LT; Tsai, MD	1
Cohen, GM; Milani, M; Varadarajan, S; Yedida, G	1

Other Studies

11 other study(ies) available for gossypol and cytochrome c-t

Article	Year
Involvement of reactive oxygen species-independent mitochondrial pathway in gossypol-induced apoptosis. Archives of biochemistry and biophysics, 2004, Aug-15, Volume: 428, Issue:2 Topics: Acetylcysteine; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Blotting, Western; Carrier Proteins; Caspase 3; Caspase 8; Caspase 9; Caspases; Catalase; Cell Survival; Contraceptive Agents, Male; Cytochromes c; Cytosol; DNA Fragmentation; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Flow Cytometry; Gossypol; HL-60 Cells; Humans; Membrane Potentials; Mitochondria; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Subcellular Fractions; Time Factors	2004
Preclinical studies of a nonpeptidic small-molecule inhibitor of Bcl-2 and Bcl-X(L) [(-)-gossypol] against diffuse large cell lymphoma. Molecular cancer therapeutics, 2005, Volume: 4, Issue:1 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-X Protein; Caspase 3; Caspase 9; Caspases; Cell Division; Cell Line, Tumor; Cyclophosphamide; Cytochromes c; Doxorubicin; Gossypol; Humans; Lymphoma, Large B-Cell, Diffuse; Mice; Mice, SCID; Prednisone; Proto-Oncogene Proteins c-bcl-2; Transplantation, Heterologous; Vincristine	2005
Nonpeptidic small-molecule inhibitor of Bcl-2 and Bcl-XL, (-)-Gossypol, enhances biological effect of genistein against BxPC-3 human pancreatic cancer cell line. Pancreas, 2005, Volume: 31, Issue:4 Topics: Apoptosis; bcl-X Protein; Cell Line, Tumor; Cytochromes c; Drug Synergism; Genistein; Gossypol; Humans; NF-kappa B; Pancreatic Neoplasms; Proto-Oncogene Proteins c-bcl-2	2005
Gossypol induces Bax/Bak-independent activation of apoptosis and cytochrome c release via a conformational change in Bcl-2. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2006, Volume: 20, Issue:12 Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Cytochromes c; Gossypol; Liposomes; Mice; Mice, Inbred BALB C; Mice, Knockout; Mice, Nude; Neoplasms, Experimental; Protein Conformation; Proto-Oncogene Proteins c-bcl-2; Tumor Burden	2006
Gossypol reduction of tumor growth through ROS-dependent mitochondria pathway in human colorectal carcinoma cells. International journal of cancer, 2007, Oct-15, Volume: 121, Issue:8 Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Inducing Factor; bcl-Associated Death Protein; bcl-X Protein; Blotting, Western; Caspases; Cell Line, Tumor; Cell Survival; Collagen Type XI; Colorectal Neoplasms; Cytochromes c; Enzyme Activation; Ethidium; Flow Cytometry; Gossypol; Humans; Mice; Mice, Nude; Mitochondria; Reactive Oxygen Species; Signal Transduction	2007
(-)Gossypol and its combination with imatinib induce apoptosis in human chronic myeloid leukemic cells. Leukemia & lymphoma, 2007, Volume: 48, Issue:11 Topics: Apoptosis; bcl-X Protein; Benzamides; Caspase 3; Cell Proliferation; Cytochromes c; Down-Regulation; Drug Evaluation, Preclinical; Enzyme Activation; Fusion Proteins, bcr-abl; Gossypol; Humans; Imatinib Mesylate; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Membrane Potential, Mitochondrial; Mitochondria; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Piperazines; Proto-Oncogene Proteins c-bcl-2; Pyrimidines	2007
ApoG2 inhibits antiapoptotic Bcl-2 family proteins and induces mitochondria-dependent apoptosis in human lymphoma U937 cells. Anti-cancer drugs, 2008, Volume: 19, Issue:10 Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Caspase 3; Caspase 9; Cytochromes c; DNA Fragmentation; Gossypol; Humans; Mitochondria; Myeloid Cell Leukemia Sequence 1 Protein; Proto-Oncogene Proteins c-bcl-2; U937 Cells	2008
Apogossypolone inhibits cell growth by inducing cell cycle arrest in U937 cells. Oncology reports, 2009, Volume: 22, Issue:1 Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Cell Cycle; Cell Proliferation; Cell Survival; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p21; Cytochromes c; Dose-Response Relationship, Drug; Gossypol; Humans; Lymphoma; Mitochondria; Proto-Oncogene Proteins c-myc; Time Factors; U937 Cells	2009
BH3 response profiles from neuroblastoma mitochondria predict activity of small molecule Bcl-2 family antagonists. Cell death and differentiation, 2010, Volume: 17, Issue:5 Topics: Apoptosis; Biphenyl Compounds; Cell Line; Cell Line, Tumor; Cytochromes c; Gossypol; Humans; Immunoblotting; Immunoprecipitation; Mitochondria; Neuroblastoma; Nitrophenols; Peptide Fragments; Piperazines; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Sulfonamides	2010
Involvement of Smac, p53, and caspase pathways in induction of apoptosis by gossypol in human retinoblastoma cells. Molecular vision, 2012, Volume: 18 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Caspases; Cell Line, Tumor; Cell Nucleus; Cell Survival; Cytochromes c; Dose-Response Relationship, Drug; Flow Cytometry; Gene Expression Regulation, Neoplastic; Gossypol; Humans; Intracellular Signaling Peptides and Proteins; Mitochondrial Proteins; Receptors, TNF-Related Apoptosis-Inducing Ligand; Retinal Neoplasms; Retinoblastoma; Signal Transduction; Tumor Suppressor Protein p53	2012
Apogossypol-mediated reorganisation of the endoplasmic reticulum antagonises mitochondrial fission and apoptosis. Cell death & disease, 2019, 07-08, Volume: 10, Issue:7 Topics: Apoptosis; bcl-2-Associated X Protein; Crotonates; Cytochromes c; Endoplasmic Reticulum; Gossypol; HeLa Cells; Humans; Hydroxybutyrates; Intracellular Membranes; Leflunomide; Mitochondria; Mitochondrial Dynamics; Models, Biological; Nitriles; Protein Transport; Toluidines	2019