gossypol and cyclin d1

gossypol has been researched along with cyclin d1 in 9 studies

Research

Studies (9)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (11.11)	18.2507
2000's	6 (66.67)	29.6817
2010's	2 (22.22)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Hochhauser, D; Jeoung, D; Ligueros, M; Reidenberg, MM; Sonenberg, M; Tang, B	1
Bacotti, D; Bloch, R; Borgen, P; Gollub, M; Hudis, C; Ligueros, M; Moasser, MM; Norton, L; Reidenberg, MM; Seidman, AD; Sklarin, N; Sonenberg, M; Van Poznak, C; Van Zee, K; Yao, TJ	1
Guo, R; Li, B; Ling, Y; Liu, H; Roller, PP; Wang, S; Wu, X; Yang, D; Zhang, M	1
Aguilar-Lemarroy, AC; Barba-Barajas, L; Barba-Barajas, M; Bravo-Cuellar, A; de Celis, R; Domínguez-Rodríguez, JR; Guevara-Barraza, MG; Hernández-Flores, G; Jave-Suarez, LF; Lerma-Díaz, JM; Ortiz-Lazareno, PC	1
Hu, ZY; Jiang, WQ; Li, ZM; Sun, J; Yang, DJ; Zeng, ZL	1
Jiang, J; Lin, YC; Ye, W	1
Jen, R; Kuo, CT; Lin, SH; Lin, YC; Xu, P; Ye, W	1
Cheng, P; Dai, X; Ding, W; He, F; Lian, J; Ni, Z; Rae Smith, A; Wang, B; Wu, D; Xu, L	1
Leong, J; Lin, SH; Lin, YC; Liu, JY; Xu, P; Ye, W; Zhong, S	1

Trials

1 trial(s) available for gossypol and cyclin d1

Article	Year
Oral gossypol in the treatment of patients with refractory metastatic breast cancer: a phase I/II clinical trial. Breast cancer research and treatment, 2001, Volume: 66, Issue:3 Topics: Administration, Oral; Adult; Aged; Breast Neoplasms; Cell Cycle; Cyclin D1; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Fatigue; Female; Gossypol; Humans; Immunohistochemistry; Middle Aged; Nausea; Retinoblastoma Protein; Taste Disorders; Treatment Outcome	2001

Article

Year

Oral gossypol in the treatment of patients with refractory metastatic breast cancer: a phase I/II clinical trial.

Breast cancer research and treatment, 2001, Volume: 66, Issue:3

Topics: Administration, Oral; Adult; Aged; Breast Neoplasms; Cell Cycle; Cyclin D1; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Fatigue; Female; Gossypol; Humans; Immunohistochemistry; Middle Aged; Nausea; Retinoblastoma Protein; Taste Disorders; Treatment Outcome

2001

Other Studies

8 other study(ies) available for gossypol and cyclin d1

Article	Year
Gossypol inhibition of mitosis, cyclin D1 and Rb protein in human mammary cancer cells and cyclin-D1 transfected human fibrosarcoma cells. British journal of cancer, 1997, Volume: 76, Issue:1 Topics: Breast Neoplasms; Cell Cycle; Cyclin D1; Cyclins; Fibrosarcoma; Gossypol; Humans; Mitosis; Oncogene Proteins; Retinoblastoma Protein; Transfection; Tumor Cells, Cultured	1997
Molecular mechanism of gossypol-induced cell growth inhibition and cell death of HT-29 human colon carcinoma cells. Biochemical pharmacology, 2003, Jul-01, Volume: 66, Issue:1 Topics: Apoptosis; Apoptosis Regulatory Proteins; bcl-X Protein; Caspases; Cell Cycle; Cell Death; Colonic Neoplasms; Cyclin D1; Cytochrome c Group; Enzyme Activation; Gossypol; HT29 Cells; Humans; Poly(ADP-ribose) Polymerases; Proteins; Proto-Oncogene Proteins c-bcl-2	2003
Gossypol induced apoptosis of polymorphonuclear leukocytes and monocytes: involvement of mitochondrial pathway and reactive oxygen species. Immunopharmacology and immunotoxicology, 2009, Volume: 31, Issue:2 Topics: Adult; Antioxidants; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; bcl-Associated Death Protein; Caspases; Chromans; Cyclin D1; Female; Gossypol; Humans; Male; Membrane Potential, Mitochondrial; Mitochondria; Monocytes; Myeloid Cell Leukemia Sequence 1 Protein; Neutrophils; Phagocytosis; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Superoxide Dismutase; Tumor Suppressor Protein p53; Young Adult	2009
Apogossypolone inhibits cell growth by inducing cell cycle arrest in U937 cells. Oncology reports, 2009, Volume: 22, Issue:1 Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Cell Cycle; Cell Proliferation; Cell Survival; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p21; Cytochromes c; Dose-Response Relationship, Drug; Gossypol; Humans; Lymphoma; Mitochondria; Proto-Oncogene Proteins c-myc; Time Factors; U937 Cells	2009
Gossypol inhibits the growth of MAT-LyLu prostate cancer cells by modulation of TGFbeta/Akt signaling. International journal of molecular medicine, 2009, Volume: 24, Issue:1 Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Contraceptive Agents, Male; Cyclin D1; Gossypol; Male; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Rats; Retinoblastoma Protein; Signal Transduction; Transforming Growth Factor beta1	2009
Mitogenic activity of zeranol in human breast cancer cells is enhanced by leptin and suppressed by gossypol. Anticancer research, 2009, Volume: 29, Issue:11 Topics: Anticarcinogenic Agents; Breast Neoplasms; Cell Growth Processes; Cell Line, Tumor; Cell Transformation, Neoplastic; Cyclin D1; Drug Synergism; Gossypol; Humans; Leptin; Recombinant Proteins; RNA, Messenger; Tumor Suppressor Protein p53; Zeranol	2009
The novel BH-3 mimetic apogossypolone induces Beclin-1- and ROS-mediated autophagy in human hepatocellular carcinoma [corrected] cells. Cell death & disease, 2013, Feb-07, Volume: 4 Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Apoptosis Regulatory Proteins; Autophagy; bcl-X Protein; Beclin-1; Carcinoma, Hepatocellular; Cell Line, Tumor; Cyclin D1; Extracellular Signal-Regulated MAP Kinases; Gossypol; Hep G2 Cells; HMGB1 Protein; Humans; JNK Mitogen-Activated Protein Kinases; Liver Neoplasms; Membrane Proteins; Microtubule-Associated Proteins; Phosphorylation; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; TOR Serine-Threonine Kinases	2013
(-)-Gossypol-enriched cottonseed oil inhibits proliferation and adipogenesis of human breast pre-adipocytes. Anticancer research, 2013, Volume: 33, Issue:3 Topics: Adipocytes; Adipogenesis; Breast; CCAAT-Enhancer-Binding Protein-alpha; Cell Proliferation; Cottonseed Oil; Cyclin D1; Female; Genes, bcl-2; Gossypol; Humans; Leptin; PPAR gamma; Stem Cells	2013