Compounds > gossypol

gossypol and acetylcysteine

gossypol has been researched along with acetylcysteine in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fujii, M; Hou, DX; Imamura, I; Ose, T; Takeshita, T; Tanigawa, S; Tong, X; Uto, T1
Bauer, JA; Belbin, TJ; Bradford, CR; Brenner, JC; Carey, TE; Prystowsky, MB; Sikora, MJ; Soengas, MS; Taylor, JC; Verhaegen, M; Wang, S1
Balakrishnan, K; Gandhi, V; Keating, MJ; Wierda, WG1
Cheng, P; Dai, X; Ding, W; He, F; Lian, J; Ni, Z; Rae Smith, A; Wang, B; Wu, D; Xu, L1

Other Studies

5 other study(ies) available for gossypol and acetylcysteine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Involvement of reactive oxygen species-independent mitochondrial pathway in gossypol-induced apoptosis.
    Archives of biochemistry and biophysics, 2004, Aug-15, Volume: 428, Issue:2

    Topics: Acetylcysteine; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Blotting, Western; Carrier Proteins; Caspase 3; Caspase 8; Caspase 9; Caspases; Catalase; Cell Survival; Contraceptive Agents, Male; Cytochromes c; Cytosol; DNA Fragmentation; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Flow Cytometry; Gossypol; HL-60 Cells; Humans; Membrane Potentials; Mitochondria; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Subcellular Fractions; Time Factors

2004
Anti-oxidant treatment enhances anti-tumor cytotoxicity of (-)-gossypol.
    Cancer biology & therapy, 2008, Volume: 7, Issue:5

    Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Cell Line; Cell Line, Tumor; Cell Survival; Drug Synergism; Gene Expression Regulation, Neoplastic; Gossypol; Humans; Models, Biological; Neoplasms; Oligonucleotide Array Sequence Analysis; Oxidants; Reactive Oxygen Species

2008
Gossypol, a BH3 mimetic, induces apoptosis in chronic lymphocytic leukemia cells.
    Blood, 2008, Sep-01, Volume: 112, Issue:5

    Topics: Acetylcysteine; Adenosine Triphosphate; Amino Acid Chloromethyl Ketones; Antioxidants; Apoptosis; Apoptosis Inducing Factor; bcl-2-Associated X Protein; BH3 Interacting Domain Death Agonist Protein; Biological Transport, Active; Calpain; Caspase Inhibitors; Caspases; Cysteine Proteinase Inhibitors; Dipeptides; Gossypol; Humans; In Vitro Techniques; Leukemia, Lymphocytic, Chronic, B-Cell; Mitochondrial Membranes; Molecular Mimicry; Reactive Oxygen Species; Superoxides

2008
The novel BH-3 mimetic apogossypolone induces Beclin-1- and ROS-mediated autophagy in human hepatocellular carcinoma [corrected] cells.
    Cell death & disease, 2013, Feb-07, Volume: 4

    Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Apoptosis Regulatory Proteins; Autophagy; bcl-X Protein; Beclin-1; Carcinoma, Hepatocellular; Cell Line, Tumor; Cyclin D1; Extracellular Signal-Regulated MAP Kinases; Gossypol; Hep G2 Cells; HMGB1 Protein; Humans; JNK Mitogen-Activated Protein Kinases; Liver Neoplasms; Membrane Proteins; Microtubule-Associated Proteins; Phosphorylation; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; TOR Serine-Threonine Kinases

2013