gossylic-lactone and gossylic-nitrile-1-1--diacetate

gossylic-lactone has been researched along with gossylic-nitrile-1-1--diacetate* in 2 studies

Other Studies

2 other study(ies) available for gossylic-lactone and gossylic-nitrile-1-1--diacetate

Article	Year
A model of Plasmodium falciparum lactate dehydrogenase and its implications for the design of improved antimalarials and the enhanced detection of parasitaemia. Protein engineering, 1997, Volume: 10, Issue:4 Topics: Amino Acid Sequence; Animals; Antimalarials; Binding Sites; Crystallography, X-Ray; Drug Design; Geobacillus stearothermophilus; Gossypol; Humans; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Models, Chemical; Models, Molecular; Molecular Sequence Data; NAD; Plasmodium falciparum; Protein Structure, Tertiary; Sequence Alignment; Sequence Deletion; Stereoisomerism; Swine	1997
Inhibition of human immunodeficiency virus type I replication by derivatives of gossypol. Pharmacological research, 1991, Volume: 24, Issue:4 Gossypol (I) and its derivatives gossylic nitrile-1,1'-diacetate (II), gossylic iminolactone (III) and gossylic lactone (IV) inhibit the replication of human immunodeficiency virus type 1 in vitro in the order III greater than I greater than II,IV, indicating that derivatives of gossypol can retain antiviral activities. All of the derivatives are less cytotoxic than gossypol. Topics: Antiviral Agents; Cell Line; Cell Survival; Gossypol; HIV-1; Humans; Virus Replication	1991

Article

Year

A model of Plasmodium falciparum lactate dehydrogenase and its implications for the design of improved antimalarials and the enhanced detection of parasitaemia.

Protein engineering, 1997, Volume: 10, Issue:4

Topics: Amino Acid Sequence; Animals; Antimalarials; Binding Sites; Crystallography, X-Ray; Drug Design; Geobacillus stearothermophilus; Gossypol; Humans; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Models, Chemical; Models, Molecular; Molecular Sequence Data; NAD; Plasmodium falciparum; Protein Structure, Tertiary; Sequence Alignment; Sequence Deletion; Stereoisomerism; Swine

1997

Inhibition of human immunodeficiency virus type I replication by derivatives of gossypol.

Pharmacological research, 1991, Volume: 24, Issue:4

Gossypol (I) and its derivatives gossylic nitrile-1,1'-diacetate (II), gossylic iminolactone (III) and gossylic lactone (IV) inhibit the replication of human immunodeficiency virus type 1 in vitro in the order III greater than I greater than II,IV, indicating that derivatives of gossypol can retain antiviral activities. All of the derivatives are less cytotoxic than gossypol.

Topics: Antiviral Agents; Cell Line; Cell Survival; Gossypol; HIV-1; Humans; Virus Replication

1991