goniothalamin has been researched along with isobutyramide* in 1 studies
1 other study(ies) available for goniothalamin and isobutyramide
Article | Year |
---|---|
Synthesis of Nitrogen-Containing Goniothalamin Analogues with Higher Cytotoxic Activity and Selectivity against Cancer Cells.
Two series of racemic goniothalamin analogues displaying nitrogen-containing groups were designed and synthesized. A total of 19 novel analogues were evaluated against a panel of four different cancer cell lines, along with the normal prostate cell line PNT2 to determine their selectivity. Among them, goniothalamin chloroacrylamide 13 e displayed the lowest IC Topics: Amides; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Nitrogen; Pyrones; Structure-Activity Relationship | 2019 |