gold has been researched along with methotrexate in 134 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (24.63) | 18.7374 |
| 1990's | 48 (35.82) | 18.2507 |
| 2000's | 5 (3.73) | 29.6817 |
| 2010's | 34 (25.37) | 24.3611 |
| 2020's | 14 (10.45) | 2.80 |
| Authors | Studies |
|---|---|
| Müller, AE; Thiele, HG | 1 |
| Gallego, RE; Lynch, PJ; Saied, NK | 1 |
| Lorenzen, I | 1 |
| Callahan, LF; Marcum, SB; Pincus, T | 1 |
| Murphy, NG | 1 |
| Rooney, M | 1 |
| Delaney, SG; Taylor, DR | 1 |
| Menninger, H | 1 |
| Clough, JD; Reardon, EV | 1 |
| Alvarez, J; Szefler, SJ | 1 |
| DiSilvestro, RA; Marten, J; Skehan, M | 1 |
| Bloch, DA; Fries, JF; Singh, G; Spitz, P; Williams, CA; Zatarain, E | 1 |
| Herborn, G; Karger, T; Rau, R; Werdier, D | 1 |
| Bahremand, M; Schumacher, HR | 1 |
| Paulus, HE | 1 |
| Calin, A; Elswood, J | 1 |
| Anderson, JJ; Felson, DT; Meenan, RF | 1 |
| Anderson, L; Block, S; Germain, BF; Irby, R; Kaplan, H; Merriman, RC; Solomon, SD; Wall, B; Weinblatt, ME; Wolfe, F | 1 |
| McDuffie, FC | 1 |
| Ward, MJ; White, JP | 1 |
| Andreu, JL; Angeles Trujillo, M; Isasi, C; López-Martín, JA; Mulero, J; Palacio, S | 1 |
| Rosenberg, AM | 1 |
| Hardin, JG | 1 |
| Brooks, PM; O'Callaghan, JW | 1 |
| Clegg, DO; Ward, JR | 1 |
| Cloutier, JM; Martel-Pelletier, J; Pelletier, JP | 1 |
| Høyeraal, HM | 1 |
| Galivan, J; Kerwar, SS; Oronsky, AL; Rath, N; Ridge, SC; Zabriske, J | 1 |
| Rau, R | 1 |
| Docken, WP; Warfield, CA | 1 |
| Pugh, CB; Pugh, MC | 1 |
| Karger, T; Rau, R | 1 |
| Dugowson, CE; Gilliland, BC | 1 |
| Polisson, RP; St Clair, EW | 1 |
| Bloch, DA; Fries, JF; Mitchell, DM; Roth, SH; Spitz, PW; Wolfe, F | 1 |
| Willkens, RF | 1 |
| Kremer, JM | 1 |
| Kovarsky, J | 1 |
| Caspi, D; Tishler, M; Yaron, M | 1 |
| Braunsteiner, H; Günther, R; Huber, C; Huber, H; Michlmayr, G | 1 |
| Kölle, G | 1 |
| Maggioni, G | 1 |
| Buchman, VM; Kozlova, MD; Levin, VJ; Mikaelian, SE; Radzichovskaya, RM; Svet-Moldavsky, GJ | 1 |
| Brooks, PM; Buchanan, WW; Kassam, Y; Kean, WF | 1 |
| Muller, SA; Perry, HO; Poulin, Y | 1 |
| Krall, PL; Wilke, WS | 1 |
| Hill, JM; Tattersfield, AE | 1 |
| Brooks, P; Conaghan, PG | 3 |
| Klama, K; Lacki, JK; Mackiewicz, SH; Mackiewicz, U; Müller, W | 1 |
| Bijlsma, JW; Jacobs, JW; Schenk, Y; van der Heide, A | 1 |
| Megyeri, A; Merétey, K; Schmidt, Z; Szilágyi, M | 1 |
| Bensen, W; Gent, M; Grace, E; Ludwin, D; Roberts, RM; Ross, H; Tugwell, P | 1 |
| Moss, RB | 1 |
| Meenan, RF; Prashker, MJ | 1 |
| Bijlsma, JW; Geertzen, RG; van den Brink, HR; van Wijk, MJ | 1 |
| Brooks, P; Conaghan, PG; Girgis, L | 1 |
| Bruno, M; Cosseddu, D; Linari, F; Manganaro, M; Pellerito, R; Ravarino, N; Torchio, B; Urbano, D | 1 |
| Braig, K; Furuya, F; Hainfeld, JF; Horwich, AL; Simon, M | 1 |
| Clemmey, P; Culbertson, AL; Lewis, C; Nicassio, PM; Radojevic, V; Weisman, MH | 1 |
| McGuire, JL; Ridgway, WM | 1 |
| Edmonds, JP; Furst, DE; Paulus, HE; Scott, DL | 1 |
| Herborn, G; Rau, R; Wassenberg, S | 1 |
| Criswell, LA; Henke, CJ | 1 |
| Lombard, MG; O'Toole, PA; Phelan, M; Sykes, H; Thompson, RN | 1 |
| Cush, J; Heudebert, G; Jain, R; Kavanaugh, A | 1 |
| Capell, HA; Duncan, MR | 1 |
| Georgou, TA; Hunninghake, GW; Koehnke, RK; Kolluri, S; Rachow, JW; Saag, KG; Schwartz, DA | 1 |
| Barnes, PJ | 1 |
| Avina-Zubieta, JA; Fitzgerald, A; Galindo-Rodriguez, G; LeClerq, SA; Russell, AS; Suarez-Almazor, ME | 1 |
| Fries, JF; Ramey, DR; Singh, G; Williams, CA | 1 |
| Brooks, P; Conaghan, PG; Lehmann, T | 1 |
| Criswell, LA; Such, CL; Yelin, EH | 1 |
| Hannonen, PJ; Kautiainen, HJ; Sokka, TM | 1 |
| Ali, AA; Beg, JA; Hussain, MA; Iqbal, MP; Mehboobali, N; Rahbar, MH | 1 |
| Herborn, G; Karger, T; Rau, R; Schleusser, B | 1 |
| Scarpa, R | 1 |
| Cintero, MI; Mateo, L; Romera, M; Rozadilla, A | 1 |
| Argyros, G; Niven, AS | 1 |
| ARIEL, IM; GALEY, D; RESNICK, MI | 1 |
| Canvin, J; Esdaile, JM; Fitzgerald, A; Grant, E; Klinkhoff, AV; Lehman, AJ | 1 |
| Bieber, T; Tüting, T; Uerlich, M; Wenzel, J | 1 |
| Kean, IR; Kean, WF | 1 |
| Afif, N; Chatelus, E; Goetz, J; Lipsker, D; Sibilia, J; Sordet, C; Sparsa, L | 1 |
| Cortie, MB; Niidome, T; Pissuwan, D | 1 |
| Ditzler, LR; Gannon, MJ; Kohen, A; Sen, A; Tivanski, AV | 1 |
| Chen, X; Chen, Z; Gao, W; Lin, Y; Qian, S | 1 |
| Bichelberger, MA; Colin, DY; Masson, JF; Pelletier, JN; Robitaille, R; Zhao, SS | 1 |
| Ha, YJ; Kim, HJ; Lee, SK; Lee, SM; Park, YB; Park, YN; Yoo, KH | 1 |
| Huang, C; Kang, ET; Lu, S; Neoh, KG; Shi, Z | 1 |
| Murawala, P; Prasad, BL; Shiras, A; Tirmale, A | 1 |
| Bukar, N; Charbonneau, DM; Masson, JF; Pelletier, JN; Zhao, SS | 1 |
| Costa Lima, SA; Reis, S | 1 |
| Kim, HJ; Lee, SM; Mun, CH; Park, KH; Park, YB; Yoo, KH | 1 |
| Bukar, N; Masson, JF; Pelletier, JN; Toulouse, JL; Yockell-Lelièvre, H | 1 |
| Dai, C; Huo, X; Li, S; Li, X; Tian, D | 1 |
| Dey, S; Rekha, MR; Sherly, MC; Sreenivasan, K | 1 |
| Azzoni, P; Benassi, L; Bessar, H; Botti, E; Casagrande, V; Costanzo, A; Federici, M; Fontana, L; Fratoddi, I; Ibrahim, SA; Magnoni, C; Mostafa, FF; Pellacani, G; Russo, MV; Testa, G; Vaschieri, C; Venditti, I | 1 |
| Li, SP; Li, XD; Sha, ZL; Tian, DY; Wang, WY | 1 |
| Christoforou, N; Lee, S; Rizk, N | 1 |
| Bonifacio, A; Fornasaro, S; Marta, SD; Rabusin, M; Sergo, V | 1 |
| Arsalani, N; Entezami, AA; Ghorbani, M; Hamishehkar, H | 1 |
| Ju, XH; Li, SP; Li, XD; Wang, L; Wang, WY; Wang, Y; Zhao, XF | 1 |
| Ghorbani, M; Hamishehkar, H | 1 |
| Cong, VT; Joo, SW; Ly, NH; Min, J; Son, SJ | 1 |
| Geladi, P; Lindholm-Sethson, B; Phal, S; Shchukarev, A; Tesfalidet, S | 1 |
| Ju, XH; Li, J; Li, SP; Li, XD; Liu, P; Song, FG; Tang, YW; Wang, WY; Zhao, XF | 1 |
| Chatterjee, B; Ghosh, SS; Raza, A | 1 |
| Gowthaman, MK; Gunadharini, DN; Hemalatha, T; Prabu, P | 1 |
| Abbasian, M; Fallah Iri Sofla, S; Mirzaei, M | 1 |
| Chung, RJ; Dhawan, U; Li, YQ; Lin, C; Liu, WC; Liu, XR; Wu, KT; Wu, YC; Xu, M; Zhao, G | 1 |
| Luo, F; Wu, S; Wu, T; Xu, P; Yan, J; Yang, X; Zou, M | 1 |
| Azzoni, P; Benassi, L; Bessar, H; Bianchi, L; Botti, E; Casagrande, V; Costanzo, A; Federici, M; Fratoddi, I; Magnoni, C; Pellacani, G; Samir, MA; Vaschieri, C; Venditti, I | 1 |
| Gondaliya, P; Kalia, K; Maheshwari, R; Pandey, PK; Raval, N; Tekade, RK | 1 |
| Gan, F; Meng, F; Ye, G | 1 |
| Koul, V; Kumar Dinda, A; Kumar, A; Naz, F | 1 |
| Capocefalo, A; Domenici, F; Fasolato, C; Giantulli, S; Mazzarda, F; Notariello, D; Postorino, P; Silvestri, I; Toumia, Y | 1 |
| Akdis, CA; Boyman, O; Hafner, J; Impellizzieri, D; Kolios, AGA; Kurzbach, D; Nguyen, TT; Nilsson, J; Özcan, A; Sahin, D; Tan, G; Yawalkar, N | 1 |
| Arda, N; Emik, S; Gürdağ, G; Önay-Uçar, E; Şengelen, A; Yücel, O | 1 |
| Cheng, Z; Chin, FT; Ding, B; Klockow, JL; Lau, K; Liu, H; Zhang, Y; Zhao, N | 1 |
| Kaur, G; Matai, I; Mishra, S; Sachdev, A; Soni, S | 1 |
| Battocchio, C; Beltrán, AM; Cerra, S; Del Giudice, A; Familiari, G; Fratoddi, I; Matassa, R; Pis, I; Scaramuzzo, FA; Sciubba, F | 1 |
| Álvarez, MA; Álvarez-González, B; Fernández-Perales, M; Rozalen, M; Sánchez-Polo, M | 1 |
| Cao, Z; Huang, Q; Li, W; Liu, Y; Lu, A; Lu, C; Yu, L; Zhu, D | 1 |
| Acosta, G; Albericio, F; Araya, E; Bolaños, K; Giralt, E; Kogan, MJ; Sánchez-Navarro, M | 1 |
| Li, C; Li, X; Su, H; Wang, H; Zou, X | 1 |
| Boisen, A; Dumont, E; Göksel, Y; Rajendran, ST; Rindzevicius, T; Sarikaya, S; Schmiegelow, K; Slipets, R; Thamdrup, LHE; Zor, K | 1 |
| Barakat, MK; Ismail, CA; Rafik, ST; Shalaby, TI; Zeitoun, TM | 1 |
| Agostinelli, E; Battocchio, C; Canettieri, G; Cerra, S; Chumakov, A; Davydok, A; Del Giudice, A; Fratoddi, I; Grigorian, S; Marsotto, M; Matassa, R; Nottola, S; Pennacchi, B; Rutigliano, L; Salamone, TA; Sciubba, F | 1 |
| Al-Rejaie, SS; Baker, A; Elgorban, AM; Khan, MS; Mohany, M; Syed, A | 1 |
| Khan, MR; Sen Sarma, N; Sultana, N; Thanil Singh, C | 1 |
34 review(s) available for gold and methotrexate
| Article | Year |
|---|---|
Treatment of rheumatoid arthritis with cytostatic drugs.
Topics: Antineoplastic Agents; Arthritis, Rheumatoid; Azathioprine; Chlorambucil; Cyclophosphamide; Gold; Humans; Immunosuppression Therapy; Methotrexate; Time Factors | 1975 |
Current concepts in the management of rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Aged; Antibiotics, Antineoplastic; Antirheumatic Agents; Arthritis, Rheumatoid; Drug Combinations; Female; Gold; Humans; Male; Methotrexate; Middle Aged; Penicillamine; Research Design; Sulfasalazine | 1992 |
Is there a disease-modifying drug for juvenile chronic arthritis?
Topics: Administration, Oral; Antimalarials; Arthritis, Juvenile; Child; Forecasting; Gold; Humans; Immunization, Passive; Methotrexate; Penicillamine; Rheumatology; Sulfasalazine | 1992 |
Steroid-sparing agents in the treatment of asthma.
Topics: Asthma; Gold; Humans; Methotrexate; Troleandomycin | 1992 |
Alternative therapy in severe asthma.
Topics: Anti-Inflammatory Agents; Asthma; Auranofin; Gold; Humans; Immunoglobulins, Intravenous; Methotrexate; Troleandomycin | 1992 |
The use of combinations of disease-modifying antirheumatic agents in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Arthritis, Rheumatoid; Clinical Trials as Topic; Cyclophosphamide; Drug Combinations; Gold; Humans; Methotrexate; Penicillamine; Sulfasalazine | 1990 |
The comparative efficacy and toxicity of second-line drugs in rheumatoid arthritis. Results of two metaanalyses.
Topics: Antimalarials; Arthritis, Rheumatoid; Auranofin; Gold; Humans; Meta-Analysis as Topic; Methotrexate; Penicillamine; Sulfasalazine | 1990 |
Drug-induced adverse pulmonary reactions.
Topics: Amiodarone; Asthma; Bleomycin; Carmustine; Drug-Related Side Effects and Adverse Reactions; Gold; Humans; Hydrochlorothiazide; Hypertension, Pulmonary; Lung Diseases; Lupus Erythematosus, Systemic; Lymphatic Diseases; Mediastinum; Methotrexate; Nitrofurantoin; Penicillamine; Pleural Effusion; Pulmonary Edema; Pulmonary Eosinophilia; Pulmonary Fibrosis; Ritodrine | 1985 |
Advanced drug therapy for juvenile rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Antimalarials; Arthritis, Juvenile; Child; Gold; Humans; Immunosuppressive Agents; Methotrexate; Penicillamine; Sulfasalazine | 1989 |
Rheumatoid arthritis therapy: the slow-acting agents.
Topics: Age Factors; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Arthritis, Rheumatoid; Auranofin; Aurothioglucose; Azathioprine; Cyclophosphamide; Gold; Gold Sodium Thiomalate; Humans; Methotrexate; Penicillamine; Prognosis; Steroids; Sulfasalazine; Time Factors | 1989 |
Disease-modifying agents and immunosuppressive drugs in the elderly.
Topics: Adrenal Cortex Hormones; Aged; Anti-Inflammatory Agents; Antimalarials; Azathioprine; Cyclophosphamide; Gold; Humans; Immunosuppressive Agents; Kinetics; Methotrexate; Penicillamine; Rheumatic Diseases; Sulfasalazine | 1986 |
Immunoregulatory drugs in the treatment of juvenile rheumatoid arthritis (JRA).
Topics: Adjuvants, Immunologic; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Clinical Trials as Topic; Cyclosporins; Gold; Humans; Hydroxychloroquine; Methotrexate | 1988 |
Rheumatologic causes of pain: rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Gold; Hip Prosthesis; Humans; Methotrexate; Pain; Steroids | 1988 |
Current concepts in clinical therapeutics: disease-modifying drugs for rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Arthritis, Rheumatoid; Azathioprine; Bone Marrow; Cyclophosphamide; Digestive System; Female; Gold; HLA Antigens; Humans; Joints; Male; Methotrexate; Penicillamine; Prognosis; Synovitis | 1987 |
Management of rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Azathioprine; Chloroquine; Cyclophosphamide; Drug Therapy, Combination; Felty Syndrome; Gold; Humans; Hydroxychloroquine; Immunosuppressive Agents; Leukapheresis; Lung Diseases; Lymphoid Tissue; Methotrexate; Penicillamine; Plasmapheresis; Radiotherapy; Rheumatic Diseases; Salicylates; Sjogren's Syndrome; Spinal Diseases; Vasculitis | 1986 |
Therapeutic approaches to the treatment of rheumatoid disease.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Azathioprine; Blood Component Removal; Cyclophosphamide; Exercise Therapy; Gold; Humans; Injections; Methotrexate; Patient Education as Topic; Penicillamine; Rest; Salicylates; Self-Help Devices | 1986 |
Short term efficacy of methotrexate in the treatment of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Double-Blind Method; Drug Resistance; Gold; Humans; Immunosuppression Therapy; Methotrexate; Pancytopenia; Penicillamine; Placebos; Psoriasis | 1985 |
Longterm methotrexate therapy in rheumatoid arthritis: a review.
Topics: Arthritis, Rheumatoid; Biopsy; Chemical and Drug Induced Liver Injury; Drug Resistance; Gold; Humans; Hydroxychloroquine; Liver Diseases; Liver Function Tests; Methotrexate; Penicillamine; Prednisone; Psoriasis; Risk | 1985 |
Problems of antiarthritic therapy in the elderly.
Topics: Adrenal Cortex Hormones; Age Factors; Aged; Allopurinol; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Chloroquine; Female; Gold; Gout; Humans; Male; Methotrexate; Middle Aged; Osteoarthritis; Penicillamine; Probenecid | 1984 |
Corticosteroid sparing agents in asthma.
Topics: Adrenal Cortex Hormones; Asthma; Cyclosporine; Gold; Humans; Hydroxychloroquine; Methotrexate | 1995 |
Disease-modifying antirheumatic drugs, including methotrexate, gold, antimalarials, and D-penicillamine.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Antirheumatic Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Cysteine; Drug Therapy, Combination; Gold; Humans; Methotrexate; Penicillamine; Sulfasalazine | 1995 |
Alternative pharmacotherapies for steroid-dependent asthma.
Topics: Adrenal Cortex Hormones; Asthma; Clinical Trials as Topic; Cyclosporine; Dapsone; Furosemide; Gold; Humans; Hydroxychloroquine; Magnesium Sulfate; Methotrexate; Treatment Outcome; Troleandomycin | 1995 |
Disease-modifying antirheumatic drugs, including methotrexate, sulfasalazine, gold, antimalarials, and penicillamine.
Topics: Age Factors; Antimalarials; Arthritis, Rheumatoid; Clinical Trials as Topic; Cysteine; Digestive System; Gold; Humans; Liver; Methotrexate; Penicillamine; Sulfasalazine | 1994 |
[Renal damage in rheumatoid arthritis].
Topics: Adult; Amyloidosis; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cyclosporine; Female; Glomerulonephritis; Gold; Humans; Kidney Diseases; Kidney Failure, Chronic; Male; Methotrexate; Middle Aged; Penicillamine; Vasculitis | 1994 |
Disease-modifying antirheumatic drugs, including methotrexate, sulfasalazine, gold, antimalarials, and D-penicillamine.
Topics: Anti-Inflammatory Agents; Antimalarials; Drug Therapy, Combination; Gold; Humans; Methotrexate; Penicillamine; Rheumatic Diseases; Sulfasalazine | 1993 |
Disease-modifying antirheumatic drugs, including methotrexate, gold, sulfasalazine, antimalarials, and D-penicillamine.
Topics: Antimalarials; Antirheumatic Agents; Gold; Humans; Methotrexate; Penicillamine; Sulfasalazine | 1996 |
The use of antimalarials in combination with other disease modifying agents in RA--the British experience.
Topics: Antimalarials; Antineoplastic Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Drug Therapy, Combination; Gold; Humans; Methotrexate; Penicillamine; Retina; Sulfasalazine; United Kingdom | 1996 |
Immunomodulation as asthma therapy: where do we stand?
Topics: Adjuvants, Immunologic; Administration, Inhalation; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Anti-Bacterial Agents; Antibodies, Monoclonal; Asthma; Bronchodilator Agents; Cell Adhesion; Cromolyn Sodium; Cyclosporine; Cytokines; Gold; Humans; Immunoglobulin G; Immunosuppressive Agents; Macrolides; Methotrexate; Nedocromil; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Theophylline | 1996 |
Disease-modifying antirheumatic drugs.
Topics: Antimalarials; Antirheumatic Agents; Arthritis, Rheumatoid; Drug Therapy, Combination; Gold; Humans; Methotrexate; Penicillamine; Sulfasalazine | 1997 |
Psoriatic arthritis. Is something changing?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis; Arthritis, Psoriatic; Cyclosporine; Gold; Humans; Methotrexate; Spondylitis, Ankylosing; Sulfasalazine | 1999 |
Alternate treatments in asthma.
Topics: Anti-Asthmatic Agents; Anticoagulants; Asthma; Cyclosporine; Diuretics; Folic Acid Antagonists; Furosemide; Gold; Heparin; Humans; Immunoglobulins, Intravenous; Immunosuppressive Agents; Methotrexate; T-Lymphocytes; Troleandomycin | 2003 |
[Systemic treatment of cutaneous lupus erythematosus].
Topics: Acute Disease; Administration, Oral; Adrenal Cortex Hormones; Adult; Antibodies, Monoclonal; Antimalarials; Azathioprine; Clinical Trials as Topic; Cyclophosphamide; Dapsone; Dermatologic Agents; Female; Gold; Humans; Immunologic Factors; Immunosuppressive Agents; Interferon-alpha; Lupus Erythematosus, Cutaneous; Male; Methotrexate; Plasmapheresis; Pregnancy; Retinoids; Thalidomide; Time Factors | 2003 |
Clinical pharmacology of gold.
Topics: Auranofin; Gold; Humans; Methotrexate; Rheumatic Diseases | 2008 |
The forthcoming applications of gold nanoparticles in drug and gene delivery systems.
Topics: Animals; Drug Carriers; Gene Transfer Techniques; Gold; Humans; Metal Nanoparticles; Methotrexate; Pharmaceutical Preparations; Polyethylene Glycols; Solubility; Surface Properties | 2011 |
15 trial(s) available for gold and methotrexate
| Article | Year |
|---|---|
Steroid-sparing agents in the treatment of asthma.
Topics: Asthma; Gold; Humans; Methotrexate; Troleandomycin | 1992 |
Toxicity profiles of disease modifying antirheumatic drugs in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; Cyclophosphamide; Female; Follow-Up Studies; Gold; Humans; Hydroxychloroquine; Male; Methotrexate; Middle Aged; Penicillamine | 1991 |
The use of combinations of disease-modifying antirheumatic agents in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Arthritis, Rheumatoid; Clinical Trials as Topic; Cyclophosphamide; Drug Combinations; Gold; Humans; Methotrexate; Penicillamine; Sulfasalazine | 1990 |
The comparative efficacy and toxicity of second-line drugs in rheumatoid arthritis. Results of two metaanalyses.
Topics: Antimalarials; Arthritis, Rheumatoid; Auranofin; Gold; Humans; Meta-Analysis as Topic; Methotrexate; Penicillamine; Sulfasalazine | 1990 |
Low-dose methotrexate compared with auranofin in adult rheumatoid arthritis. A thirty-six-week, double-blind trial.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Auranofin; Dose-Response Relationship, Drug; Double-Blind Method; Female; Gold; Humans; Male; Methotrexate; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic | 1990 |
Immunoregulatory drugs in the treatment of juvenile rheumatoid arthritis (JRA).
Topics: Adjuvants, Immunologic; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Clinical Trials as Topic; Cyclosporins; Gold; Humans; Hydroxychloroquine; Methotrexate | 1988 |
Short term efficacy of methotrexate in the treatment of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Double-Blind Method; Drug Resistance; Gold; Humans; Immunosuppression Therapy; Methotrexate; Pancytopenia; Penicillamine; Placebos; Psoriasis | 1985 |
Circulating interleukin 10 and interleukin-6 serum levels in rheumatoid arthritis patients treated with methotrexate or gold salts: preliminary report.
Topics: Adult; Aged; Arthritis, Rheumatoid; Enzyme-Linked Immunosorbent Assay; Female; Gold; Humans; Injections, Intramuscular; Interleukin-10; Interleukin-6; Male; Methotrexate; Middle Aged | 1995 |
Endpoint measures in rheumatoid arthritis clinical trials: group summary and individual patient analysis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Data Interpretation, Statistical; Disability Evaluation; Disease Progression; Female; Gold; Humans; Hydroxychloroquine; Male; Methotrexate; Middle Aged; Penicillamine; Prospective Studies; Surveys and Questionnaires; Treatment Outcome | 1994 |
[Low-dose methotrexate therapy of rheumatoid arthritis in the elderly].
Topics: Age Factors; Aged; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Female; Gold; Humans; Male; Methotrexate; Prednisolone | 1995 |
Combination therapy of cyclosporine with methotrexate and gold in rheumatoid arthritis (2 pilot studies).
Topics: Adult; Arthritis, Rheumatoid; Blood Pressure; Blood Urea Nitrogen; Creatinine; Cyclosporine; Drug Therapy, Combination; Female; Gold; Humans; Liver Function Tests; Male; Methotrexate; Middle Aged; Pilot Projects | 1994 |
The role of helplessness in the response to disease modifying drugs in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Behavior; Cognition; Disability Evaluation; Female; Gold; Helplessness, Learned; Humans; Joints; Male; Methotrexate; Middle Aged; Outcome Assessment, Health Care; Pain; Self Disclosure; Severity of Illness Index; Sulfasalazine; Time Factors | 1993 |
Duodenal mucosal ferritin in rheumatoid arthritis: implications for anaemia of chronic disease.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Duodenum; Female; Ferritins; Gastric Mucosa; Gold; Humans; Intestinal Absorption; Intestinal Mucosa; Male; Methotrexate; Middle Aged | 1996 |
Longterm combination therapy of refractory and destructive rheumatoid arthritis with methotrexate (MTX) and intramuscular gold or other disease modifying antirheumatic drugs compared to MTX monotherapy.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cohort Studies; Drug Therapy, Combination; Female; Gold; Humans; Male; Methotrexate; Middle Aged; Prospective Studies; Treatment Outcome | 1998 |
A 48-week, randomized, double-blind, double-observer, placebo-controlled multicenter trial of combination methotrexate and intramuscular gold therapy in rheumatoid arthritis: results of the METGO study.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Double-Blind Method; Drug Therapy, Combination; Female; Gold; Humans; Injections, Intramuscular; Male; Methotrexate; Middle Aged; Time Factors | 2005 |
90 other study(ies) available for gold and methotrexate
| Article | Year |
|---|---|
[On the mode of action of antirheumatic drugs (author's transl)].
Topics: Antibiotics, Antineoplastic; Arthritis, Rheumatoid; Azathioprine; Chloroquine; Gold; Gold Sodium Thiosulfate; Humans; Methotrexate; Microsomes, Liver; Penicillamine | 1976 |
Pemphigus -- a review.
Topics: Adrenal Cortex Hormones; Adult; Age Factors; Aged; Autoimmune Diseases; Azathioprine; Blister; Cyclophosphamide; Ethnicity; Female; Gold; Humans; Male; Methotrexate; Middle Aged; Pemphigus; Prognosis | 1976 |
Longterm drug therapy for rheumatoid arthritis in seven rheumatology private practices: II. Second line drugs and prednisone.
Topics: Age Factors; Arthritis, Rheumatoid; Azathioprine; Drug Therapy, Combination; Gold; Humans; Hydroxychloroquine; Long-Term Care; Methotrexate; Middle Aged; Penicillamine; Prednisone; Private Practice | 1992 |
[Gold therapy in chronic polyarthritis].
Topics: Arthritis, Rheumatoid; Gold; Humans; Injections, Intramuscular; Methotrexate; Prospective Studies; Randomized Controlled Trials as Topic; Time Factors | 1992 |
Drug therapy in the rheumatic diseases.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Gold; Humans; Hydroxychloroquine; Lupus Erythematosus, Systemic; Methotrexate; Osteoarthritis; Penicillamine; Rheumatic Diseases | 1992 |
Effects of copper supplementation on ceruloplasmin and copper-zinc superoxide dismutase in free-living rheumatoid arthritis patients.
Topics: Adult; Arthritis, Rheumatoid; Ceruloplasmin; Copper; Drug Therapy, Combination; Erythrocytes; Female; Gold; Humans; Male; Methotrexate; Middle Aged; Orosomucoid; Superoxide Dismutase | 1992 |
Retardation of radiologic progression in rheumatoid arthritis with methotrexate therapy. A controlled study.
Topics: Adult; Aged; Arthritis, Rheumatoid; Arthrography; Female; Gold; Humans; Male; Methotrexate; Middle Aged; Prospective Studies | 1991 |
Effect of medication on synovial fluid leukocyte differentials in patients with rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Female; Gold; Humans; Hydroxychloroquine; Leukocytes; Male; Methotrexate; Synovial Fluid | 1991 |
A prospective nationwide cross-sectional study of NSAID usage in 1331 patients with ankylosing spondylitis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Cross-Sectional Studies; Diclofenac; Female; Gold; Humans; Ibuprofen; Male; Methotrexate; Middle Aged; Naproxen; Penicillamine; Piroxicam; Prednisolone; Prospective Studies; Spondylitis, Ankylosing; Sulfasalazine; United Kingdom | 1990 |
How we got to be where we are.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Europe; Gold; History, 20th Century; Humans; Methotrexate; Rheumatology; United States | 1990 |
Felty's syndrome: response to low dose oral methotrexate.
Topics: Administration, Oral; Arthritis, Rheumatoid; Drug Resistance; Felty Syndrome; Female; Gold; Humans; Lithium; Lithium Carbonate; Methotrexate; Middle Aged | 1989 |
Drugs for rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Azathioprine; Cyclophosphamide; Gold; Humans; Hydroxychloroquine; Methotrexate; Penicillamine; Salicylates; Sulfasalazine | 1989 |
Slow-acting anti-rheumatic drug therapy for rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Azathioprine; Cyclophosphamide; Gold; Humans; Hydroxychloroquine; Methotrexate; Penicillamine; Sulfasalazine | 1987 |
In vivo effects of antirheumatic drugs on neutral collagenolytic proteases in human rheumatoid arthritis cartilage and synovium.
Topics: Adult; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cartilage, Articular; Collagen; DNA; Gold; Humans; Methotrexate; Middle Aged; Peptide Hydrolases; Serine Endopeptidases; Steroids; Synovial Membrane | 1988 |
Studies on the effect of D-penicillamine, gold thioglucose and methotrexate on streptococcal cell wall arthritis.
Topics: Animals; Arthritis, Infectious; Aurothioglucose; Cell Wall; Concanavalin A; Disease Models, Animal; Female; Gold; Interleukin-2; Methotrexate; Penicillamine; Rats; Rats, Inbred Lew; Spleen; Streptococcal Infections | 1986 |
[Long-term course of chronic polyarthritis under basic medication].
Topics: Arthritis, Rheumatoid; Follow-Up Studies; Gold; Humans; Methotrexate; Radiography; Time Factors | 1988 |
[Treatment of chronic polyarthritis with low-dose methotrexate].
Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents; Arthritis, Rheumatoid; Chloroquine; Drug Evaluation; Drug Therapy, Combination; Female; Gold; Humans; Male; Methotrexate; Middle Aged; Penicillamine; Time Factors | 1988 |
Impact of specific therapy upon rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Drug Evaluation; Drug Therapy; Female; Gold; Humans; Male; Methotrexate; Middle Aged; Office Visits; Outcome and Process Assessment, Health Care; Penicillamine; Prospective Studies | 1986 |
Slow acting anti-rheumatic drugs in the treatment of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Aurothioglucose; Azathioprine; Cyclophosphamide; Gold; Gold Sodium Thiomalate; Humans; Hydroxychloroquine; Methotrexate; Penicillamine | 1985 |
C-reactive protein levels in patients with rheumatoid arthritis: the impact of therapy.
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Blood Sedimentation; C-Reactive Protein; Female; Gold; Humans; Male; Methotrexate; Middle Aged; Penicillamine; Prednisone | 1985 |
[DNA-synthesizing lymphocytes in the blood of patients with disseminated lupus erythematosus, rheumatoid arthritis, and panarteritis nodosa (author's transl)].
Topics: Adult; Aged; Arthritis, Rheumatoid; Azathioprine; Chloroquine; DNA; Female; Gold; Humans; Indomethacin; Leukocyte Count; Lupus Erythematosus, Systemic; Lymphocytes; Male; Methotrexate; Methylprednisolone; Middle Aged; Penicillamine; Polyarteritis Nodosa | 1973 |
[Long term therapy of rheumatoid arthritis in children].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Arthritis, Juvenile; Azathioprine; Child; Chloroquine; Gold; Humans; Indomethacin; Long-Term Care; Manipulation, Orthopedic; Methotrexate; Phenylbutazone; Physical Therapy Modalities; Pyrazoles; Salicylates; Synovectomy; Uveitis, Anterior | 1970 |
[Therapy of rheumatoid disease in the child].
Topics: Arthritis, Juvenile; Aspirin; Child; Chlorambucil; Diet Therapy; Gold; Humans; Methotrexate; Prednisone | 1972 |
Psoriatic arthritis.
Topics: Arthritis; Aspirin; Glucocorticoids; Gold; Humans; Methotrexate; Psoriasis | 1973 |
Loading of the reticuloendothelial system: effect on the induction, development and chemotherapy of Rauscher virus leukemia.
Topics: Animals; Gold; Injections, Intraperitoneal; Leukemia, Experimental; Methotrexate; Mice; Mice, Inbred BALB C; Mononuclear Phagocyte System; Organ Size; Rauscher Virus; Spleen | 1973 |
Pemphigus vulgaris: results of treatment with gold as a steroid-sparing agent in a series of thirteen patients.
Topics: Adult; Aged; Aurothioglucose; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorescent Antibody Technique; Gold; Gold Sodium Thiomalate; Humans; Male; Methotrexate; Middle Aged; Pemphigus; Prednisone; Skin | 1984 |
Resistant rheumatoid arthritis. What to do when conservative therapy doesn't work.
Topics: Antimalarials; Arthritis, Rheumatoid; Cytotoxins; Drug Resistance; Glucocorticoids; Gold; Humans; Immunosuppressive Agents; Infusions, Parenteral; Methotrexate; Penicillamine | 1984 |
The total costs of drug therapy for rheumatoid arthritis. A model based on costs of drug, monitoring, and toxicity.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; Boston; Decision Trees; Diagnosis-Related Groups; Drug Costs; Drug Monitoring; Gold; Health Care Costs; Hospitals, University; Humans; Hydroxychloroquine; Massachusetts; Methotrexate; Models, Economic; New Hampshire; Penicillamine; Sensitivity and Specificity | 1995 |
Influence of corticosteroid pulse therapy on the serum levels of soluble interleukin 2 receptor, interleukin 6 and interleukin 8 in patients with rheumatoid arthritis.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dexamethasone; Drug Administration Schedule; Drug Therapy, Combination; Female; Gold; HLA-DR Antigens; Humans; Hydrocortisone; Infusions, Intravenous; Interleukin-6; Interleukin-8; Lymphocyte Subsets; Male; Methotrexate; Middle Aged; Receptors, Interleukin-2; Rheumatoid Factor; Sex Hormone-Binding Globulin; Sulfasalazine | 1994 |
A polypeptide bound by the chaperonin groEL is localized within a central cavity.
Topics: Bacterial Proteins; Chaperonin 60; Chromatography, Affinity; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gold; Heat-Shock Proteins; Methotrexate; Microscopy, Electron, Scanning Transmission; Protein Binding; Protein Conformation; Tetrahydrofolate Dehydrogenase | 1993 |
Aggressive drug therapy for rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Female; Gold; Humans; Life Expectancy; Male; Methotrexate; T-Lymphocytes | 1993 |
New classification of antirheumatic drugs. The evolution of a concept.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Clinical Protocols; Drug Evaluation; Gold; Humans; Methotrexate; Rheumatic Diseases; Terminology as Topic; World Health Organization | 1993 |
Can methotrexate reduce the renal toxicity of parenteral gold?
Topics: Arthritis, Rheumatoid; Female; Gold; Humans; Infusions, Parenteral; Kidney; Methotrexate; Middle Aged | 1993 |
What explains the variation among rheumatologists in their use of prednisone and second line agents for the treatment of rheumatoid arthritis?
Topics: Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Gold; Humans; Hydroxychloroquine; Male; Methotrexate; Practice Patterns, Physicians'; Prednisone; Rheumatology | 1995 |
Cost evaluation of novel therapeutics in rheumatoid arthritis (CENTRA): a decision analysis model.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cost-Benefit Analysis; Decision Support Techniques; Gold; Humans; Immunosuppressive Agents; Methotrexate; Sensitivity and Specificity | 1996 |
Rheumatoid arthritis lung disease. Determinants of radiographic and physiologic abnormalities.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Cohort Studies; Female; Gold; Humans; Lung Diseases, Interstitial; Male; Methotrexate; Middle Aged; Multivariate Analysis; Penicillamine; Prevalence; Radiography; Respiratory Function Tests; Smoking | 1996 |
Variations and trends in the prescription of initial second line therapy for patients with rheumatoid arthritis.
Topics: Antimalarials; Antirheumatic Agents; Arthritis, Rheumatoid; Auranofin; Female; Gold; Humans; Male; Methotrexate; Penicillamine; Practice Patterns, Physicians'; Rheumatology; Sulfasalazine | 1997 |
Response to therapy in rheumatoid arthritis is influenced by immediately prior therapy.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Auranofin; Disability Evaluation; Drug Administration Schedule; Female; Gold; Humans; Hydroxychloroquine; Male; Methotrexate; Middle Aged; Pain Measurement; Penicillamine; Prednisone; Retrospective Studies; Surveys and Questionnaires; Treatment Outcome | 1997 |
Differences in the use of second-line agents and prednisone for treatment of rheumatoid arthritis by rheumatologists and non-rheumatologists.
Topics: Aged; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Gold; Humans; Hydroxychloroquine; Male; Methotrexate; Middle Aged; Practice Patterns, Physicians'; Prednisone; Retrospective Studies; Rheumatology | 1997 |
A retrospective study of treating RA patients with various combinations of slow-acting antirheumatic drugs in a county hospital.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Child; Drug Therapy, Combination; Gold; Hospitals, County; Humans; Hydroxychloroquine; Methotrexate; Middle Aged; Retrospective Studies; Sulfasalazine | 1997 |
Methotrexate in rheumatoid arthritis: a 2 year experience at a university hospital in Pakistan.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Drug Therapy, Combination; Female; Follow-Up Studies; Gold; Hospitals, University; Humans; Male; Methotrexate; Middle Aged; Penicillamine; Retrospective Studies; Sulfasalazine; Treatment Outcome | 1998 |
Evaluating the safety of self-injection of gold and methotrexate in patients with inflammatory arthritis.
Topics: Antirheumatic Agents; Arthritis; Evaluation Studies as Topic; Gold; Humans; Injections; Methotrexate; Safety; Self Administration | 2000 |
THE INTRALYMPHATIC ADMINISTRATION OF RADIOACTIVE ISOTOPES AND CANCER CHEMOTHERAPEUTIC DRUGS.
Topics: Abdominal Neoplasms; Angiography; Breast Neoplasms; Geriatrics; Gold; Humans; Injections; Iodine Isotopes; Leukemia; Lymphatic Metastasis; Lymphatic System; Lymphography; Lymphoma; Lymphoma, Non-Hodgkin; Melanoma; Melphalan; Methotrexate; Neoplasms; Radioisotopes; Radionuclide Imaging; Retroperitoneal Neoplasms; Scandium; Thiotepa; Yttrium | 1964 |
Jessner-Kanof disease induced by leflunomide: a dermal variant of cutaneous lupus?
Topics: Antibodies, Antinuclear; Antirheumatic Agents; Chloroquine; Female; Gold; Humans; Interleukin 1 Receptor Antagonist Protein; Isoxazoles; Leflunomide; Lupus Erythematosus, Cutaneous; Methotrexate; Middle Aged; Treatment Outcome | 2011 |
Self-assembled enzymatic monolayer directly bound to a gold surface: activity and molecular recognition force spectroscopy studies.
Topics: Enzymes, Immobilized; Escherichia coli; Gold; Methotrexate; Microscopy, Atomic Force; Molecular Dynamics Simulation; Surface Properties; Tetrahydrofolate Dehydrogenase | 2011 |
Protein-templated gold nanoclusters as fluorescence probes for the detection of methotrexate.
Topics: Gold; Metal Nanoparticles; Methotrexate; Nanoconjugates; Optical Imaging; Serum Albumin, Bovine | 2012 |
Monitoring methotrexate in clinical samples from cancer patients during chemotherapy with a LSPR-based competitive sensor.
Topics: Antimetabolites, Antineoplastic; Chromatography, High Pressure Liquid; Drug Monitoring; Fluorescence Polarization Immunoassay; Folic Acid; Gold; Humans; Metal Nanoparticles; Methotrexate; Neoplasms; Solid Phase Extraction; Surface Plasmon Resonance; Tandem Mass Spectrometry; Tetrahydrofolate Dehydrogenase | 2012 |
Targeted chemo-photothermal treatments of rheumatoid arthritis using gold half-shell multifunctional nanoparticles.
Topics: Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Combined Modality Therapy; Gold; Hyperthermia, Induced; Metal Nanoparticles; Methotrexate; Mice; Nanocapsules; Phototherapy; Treatment Outcome | 2013 |
Polyacrylamide hybrid nanogels for targeted cancer chemotherapy via co-delivery of gold nanoparticles and MTX.
Topics: Acrylic Resins; Antimetabolites, Antineoplastic; Gels; Gold; Humans; Metal Nanoparticles; Methotrexate; Microscopy, Electron, Transmission; Neoplasms | 2013 |
In situ synthesized BSA capped gold nanoparticles: effective carrier of anticancer drug methotrexate to MCF-7 breast cancer cells.
Topics: Antineoplastic Agents; Breast Neoplasms; Caspase 3; Cell Cycle; Drug Carriers; Electrophoresis, Agar Gel; Female; Gold; Humans; Ki-67 Antigen; MCF-7 Cells; Metal Nanoparticles; Methotrexate; Serum Albumin, Bovine; Spectrophotometry, Atomic; Spectroscopy, Fourier Transform Infrared | 2014 |
Influence of the Debye length on the interaction of a small molecule-modified Au nanoparticle with a surface-bound bioreceptor.
Topics: Binding Sites; Biosensing Techniques; Folic Acid; Gold; Humans; Hydrogen-Ion Concentration; Metal Nanoparticles; Methotrexate; Osmolar Concentration; Protein Binding; Protein Structure, Tertiary; Surface Plasmon Resonance; Tetrahydrofolate Dehydrogenase | 2014 |
Temperature-responsive polymeric nanospheres containing methotrexate and gold nanoparticles: A multi-drug system for theranostic in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Gold; Humans; Metal Nanoparticles; Methotrexate; Nanospheres; Polymers; Temperature; Theranostic Nanomedicine | 2015 |
Drug-loaded gold/iron/gold plasmonic nanoparticles for magnetic targeted chemo-photothermal treatment of rheumatoid arthritis.
Topics: Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Combined Modality Therapy; Contrast Media; Delayed-Action Preparations; Diffusion; Gold; Iron; Light; Magnetic Fields; Male; Metal Nanoparticles; Methotrexate; Mice; Mice, Inbred DBA; Molecular Imaging; Nanocapsules; Particle Size; Photochemotherapy; Photosensitizing Agents; Surface Plasmon Resonance; Theranostic Nanomedicine; Treatment Outcome | 2015 |
Naked-eye nanobiosensor for therapeutic drug monitoring of methotrexate.
Topics: Colorimetry; Drug Monitoring; Enzymes, Immobilized; Gold; Humans; Metal Nanoparticles; Methotrexate; Models, Molecular; Nanotechnology; Particle Size; Protein Conformation; Surface Plasmon Resonance; Tetrahydrofolate Dehydrogenase | 2016 |
Au@SiO2 core-shell structure involved with methotrexate: Fabrication, biodegradation process and bioassay explore.
Topics: Antineoplastic Agents; Biological Assay; Cell Survival; Drug Delivery Systems; Gold; Metal Nanoparticles; Methotrexate; Silicon Dioxide | 2015 |
Alginate stabilized gold nanoparticle as multidrug carrier: Evaluation of cellular interactions and hemolytic potential.
Topics: Alginates; Animals; Biological Transport; Curcumin; Drug Carriers; Drug Stability; Glucuronic Acid; Gold; Hemolysis; Hexuronic Acids; Humans; MCF-7 Cells; Metal Nanoparticles; Methotrexate; Rats | 2016 |
Functionalized gold nanoparticles for topical delivery of methotrexate for the possible treatment of psoriasis.
Topics: Administration, Cutaneous; Animals; Cell Survival; Cells, Cultured; Dermatologic Agents; Drug Liberation; Gold; Humans; Hydrophobic and Hydrophilic Interactions; Keratinocytes; Metal Nanoparticles; Methotrexate; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Psoriasis; Skin; Skin Absorption; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Sulfhydryl Compounds | 2016 |
A novel platform designed by Au core/inorganic shell structure conjugated onto MTX/LDH for chemo-photothermal therapy.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Cell Line, Tumor; Combined Modality Therapy; Drug Delivery Systems; Drug Liberation; Gold; Humans; Hydrogen-Ion Concentration; Hyperthermia, Induced; Lung Neoplasms; Metal Nanoparticles; Methotrexate; Polyethylenes; Quaternary Ammonium Compounds | 2016 |
Optimization of anti-cancer drugs and a targeting molecule on multifunctional gold nanoparticles.
Topics: Antibodies; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Female; Folic Acid; Gold; Humans; Metal Nanoparticles; Methotrexate; Particle Size; Transforming Growth Factor beta1 | 2016 |
Toward SERS-based point-of-care approaches for therapeutic drug monitoring: the case of methotrexate.
Topics: Drug Monitoring; Gold; Humans; Metal Nanoparticles; Methotrexate; Point-of-Care Systems; Spectrum Analysis, Raman | 2016 |
A novel dual-responsive core-crosslinked magnetic-gold nanogel for triggered drug release.
Topics: Drug Carriers; Female; Gels; Gold; Humans; Magnetite Nanoparticles; MCF-7 Cells; Methacrylates; Methotrexate; Neoplasms; Polyethylene Glycols | 2016 |
Novel morphology change of Au-Methotrexate conjugates: From nanochains to discrete nanoparticles.
Topics: A549 Cells; Antineoplastic Agents; Cell Line, Tumor; Drug Delivery Systems; Drug Liberation; Ethylenediamines; Gold; Humans; Metal Nanoparticles; Methotrexate; Nanospheres; Static Electricity | 2016 |
Redox and pH-responsive gold nanoparticles as a new platform for simultaneous triple anti-cancer drugs targeting.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Doxorubicin; Drug Carriers; Drug Liberation; Drug Screening Assays, Antitumor; Gold; Humans; Hydrogen-Ion Concentration; Mercaptopurine; Metal Nanoparticles; Methotrexate; Oxidation-Reduction; Polyethylene Glycols | 2017 |
Silica-encapsulated gold nanoparticle dimers for organelle-targeted cellular delivery.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dimerization; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Screening Assays, Antitumor; Gold; HeLa Cells; Humans; Metal Nanoparticles; Methotrexate; Mice; Microscopy, Electron, Transmission; Mitochondria; Molecular Conformation; Neoplasms, Experimental; Organelles; Particle Size; Silicon Dioxide; Structure-Activity Relationship | 2017 |
Determination of methotrexate in spiked human blood serum using multi-frequency electrochemical immittance spectroscopy and multivariate data analysis.
Topics: Biosensing Techniques; Dielectric Spectroscopy; Electrochemical Techniques; Electrodes; Gold; Humans; Methotrexate; Serum | 2017 |
Induction of Au-methotrexate conjugates by sugar molecules: production, assembly mechanism, and bioassay studies.
Topics: Antimetabolites, Antineoplastic; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Dextrans; Drug Carriers; Drug Delivery Systems; Glucose; Gold; Humans; Methotrexate; Sucrose; Surface Plasmon Resonance; Time Factors | 2018 |
Developing single-entity theranostic: drug-based fluorescent nanoclusters with augmented cytotoxicity.
Topics: Apoptosis; Cell Proliferation; Cell Survival; Chitosan; Drug Delivery Systems; Gold; HeLa Cells; Humans; Metal Nanoparticles; Methotrexate; Neoplasms; Theranostic Nanomedicine | 2018 |
Fabrication and characterization of dual acting oleyl chitosan functionalised iron oxide/gold hybrid nanoparticles for MRI and CT imaging.
Topics: Animals; Cell Line, Tumor; Chitosan; Diagnostic Imaging; Drug Delivery Systems; Ferric Compounds; Gold; Humans; Magnetic Resonance Angiography; Magnetite Nanoparticles; Methotrexate; Mice; Tomography, X-Ray Computed | 2018 |
A novel gold nanorods-based pH-sensitive thiol-ended triblock copolymer for chemo-photothermo therapy of cancer cells.
Topics: Antineoplastic Agents; Combined Modality Therapy; Drug Carriers; Gold; Humans; Hyperthermia, Induced; MCF-7 Cells; Methotrexate; Nanocomposites; Nanotubes; Phototherapy; Polymers; Sulfhydryl Compounds | 2019 |
Iron-gold alloy nanoparticles serve as a cornerstone in hyperthermia-mediated controlled drug release for cancer therapy.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Survival; Delayed-Action Preparations; Drug Liberation; Gold; Gold Alloys; Hep G2 Cells; Humans; Hyperthermia, Induced; Iron; Magnetic Fields; Metal Nanoparticles; Methotrexate; Mice; Neoplasms; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction | 2018 |
Biosynthesis of flower-shaped Au nanoclusters with EGCG and their application for drug delivery.
Topics: Animals; Antineoplastic Agents; Catechin; Cell Survival; Delayed-Action Preparations; Doxorubicin; Drug Carriers; Drug Liberation; Gold; HeLa Cells; Hep G2 Cells; Humans; Metal Nanoparticles; Methotrexate; Mice, Inbred BALB C; Particle Size; Surface Properties | 2018 |
Effects of topical methotrexate loaded gold nanoparticle in cutaneous inflammatory mouse model.
Topics: Administration, Topical; Animals; Disease Models, Animal; Drug Carriers; Gold; Immunosuppressive Agents; Metal Nanoparticles; Methotrexate; Mice; Mice, Inbred C57BL; Psoriasis; Sulfhydryl Compounds | 2019 |
Nanogold-core multifunctional dendrimer for pulsatile chemo-, photothermal- and photodynamic- therapy of rheumatoid arthritis.
Topics: Animals; Arthritis, Rheumatoid; Biocompatible Materials; Biological Transport; Cell Survival; Combined Modality Therapy; Dendrimers; Drug Liberation; Gold; Hyperthermia, Induced; Indoles; Infrared Rays; Metal Nanoparticles; Methotrexate; Mice; Molecular Docking Simulation; Particle Size; Phototherapy; RAW 264.7 Cells; Reactive Oxygen Species; Surface Properties | 2019 |
Bimetallic gold/silver nanoclusters as a fluorescent probe for detection of methotrexate and doxorubicin in serum.
Topics: Antineoplastic Agents; Doxorubicin; Fluorescent Dyes; Gold; Humans; Limit of Detection; Metal Nanoparticles; Methotrexate; Silver; Spectrometry, Fluorescence; Tryptophan | 2019 |
Investigation of ultrafine gold nanoparticles (AuNPs) based nanoformulation as single conjugates target delivery for improved methotrexate chemotherapy in breast cancer.
Topics: Animals; Antimetabolites, Antineoplastic; Blood Coagulation; Breast Neoplasms; Carcinoma, Ehrlich Tumor; Cell Survival; Drug Carriers; Erythrocytes; Female; Gold; Hemolysis; Hep G2 Cells; Humans; MCF-7 Cells; Metal Nanoparticles; Methotrexate; Mice; Tumor Burden | 2019 |
Antifolate SERS-active nanovectors: quantitative drug nanostructuring and selective cell targeting for effective theranostics.
Topics: Aminopterin; Cell Line; Cell Survival; Folic Acid; Folic Acid Antagonists; Gold; Humans; Metal Nanoparticles; Methotrexate; Nanostructures; Spectrum Analysis, Raman; Theranostic Nanomedicine | 2019 |
Nanoparticle-Coupled Topical Methotrexate Can Normalize Immune Responses and Induce Tissue Remodeling in Psoriasis.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Apoptosis; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Female; Gold; Humans; Imiquimod; Immunity; Methotrexate; Mice; Mice, Inbred C57BL; Nanoparticles; Psoriasis; Skin; Th17 Cells; Xenograft Model Antitumor Assays | 2020 |
Folic acid-modified methotrexate-conjugated gold nanoparticles as nano-sized trojans for drug delivery to folate receptor-positive cancer cells.
Topics: A549 Cells; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Synergism; Folic Acid; Glutathione; Gold; HEK293 Cells; HeLa Cells; Humans; Metal Nanoparticles; Methotrexate; Particle Size; PC-3 Cells | 2020 |
Reactive oxygen species and enzyme dual-responsive biocompatible drug delivery system for targeted tumor therapy.
Topics: Drug Delivery Systems; Gold; Humans; Metal Nanoparticles; Methotrexate; Neoplasms; Reactive Oxygen Species | 2020 |
Near-infrared stimulated hydrogel patch for photothermal therapeutics and thermoresponsive drug delivery.
Topics: Alginates; Drug Carriers; Drug Liberation; Drug Stability; Gold; Graphite; Hydrogels; Infrared Rays; Methotrexate; Nanostructures; Nanotubes; Povidone; Rheology; Rhodamines; Temperature | 2020 |
Insights about the interaction of methotrexate loaded hydrophilic gold nanoparticles: Spectroscopic, morphological and structural characterizations.
Topics: Gold; Metal Nanoparticles; Methotrexate; Nanoparticles; Particle Size; Scattering, Small Angle; X-Ray Diffraction | 2020 |
Methotrexate Gold Nanocarriers: Loading and Release Study: Its Activity in Colon and Lung Cancer Cells.
Topics: A549 Cells; Annexin A5; Antineoplastic Agents; Apoptosis; Cell Death; Cell Line, Tumor; Colon; Colonic Neoplasms; Drug Delivery Systems; Drug Liberation; Folic Acid; Gold; HCT116 Cells; Humans; Hydrogen-Ion Concentration; Lung; Lung Neoplasms; Metal Nanoparticles; Methotrexate; Tumor Microenvironment | 2020 |
Hierarchical drug release designed Au @PDA-PEG-MTX NPs for targeted delivery to breast cancer with combined photothermal-chemotherapy.
Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Death; Cell Line, Tumor; Drug Liberation; Female; Gold; Humans; Metal Nanoparticles; Methotrexate; Mice, Inbred BALB C; Photothermal Therapy; Xenograft Model Antitumor Assays | 2021 |
NIR and glutathione trigger the surface release of methotrexate linked by Diels-Alder adducts to anisotropic gold nanoparticles.
Topics: Glutathione; Gold; Metal Nanoparticles; Methotrexate; Nanotubes | 2021 |
Methotrexate-loaded folic acid of solid-phase synthesis conjugated gold nanoparticles targeted treatment for rheumatoid arthritis.
Topics: Animals; Arthritis, Rheumatoid; Folic Acid; Gold; Metal Nanoparticles; Methotrexate; Mice; Nanoparticles; Rats; Solid-Phase Synthesis Techniques; Tissue Distribution | 2022 |
Methotrexate Detection in Serum at Clinically Relevant Levels with Electrochemically Assisted SERS on a Benchtop, Custom Built Raman Spectrometer.
Topics: Biological Assay; Drug Monitoring; Gold; Humans; Methotrexate; Spectrum Analysis, Raman | 2022 |
Methotrexate conjugated gold nanoparticles improve rheumatoid vascular dysfunction in rat adjuvant-induced arthritis: gold revival.
Topics: Animals; Antirheumatic Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Gold; Inflammation; Metal Nanoparticles; Methotrexate; Rats | 2023 |
Thiol functionalised gold nanoparticles loaded with methotrexate for cancer treatment: From synthesis to in vitro studies on neuroblastoma cell lines.
Topics: Drug Carriers; Gold; Humans; MCF-7 Cells; Metal Nanoparticles; Methotrexate; Nanoconjugates; Neuroblastoma; Scattering, Small Angle; Sulfhydryl Compounds; X-Ray Diffraction | 2023 |
IgG antibodies mediated gold nanoparticles conjugated to methotrexate as targeted chemotherapy for lung cancer.
Topics: Gold; Humans; Immunoglobulin G; Lung Neoplasms; Metal Nanoparticles; Methotrexate | 2023 |
An optical sensing platform for the detection of anti-cancer drugs and their cytotoxicity screening using a highly selective phosphorene-based composite.
Topics: Antineoplastic Agents; Caco-2 Cells; Cystine; Gold; Humans; Methotrexate | 2023 |